Clinical trials: Illness, Critical
Critical Illness, Acute Respiratory Failure
Feasibility of Upright Bed Position in ARDS Patients
Lower lobe atelectasis of the lung is common in Acute Respiratory Distress Syndrome (ARDS) and has the potential to adversely impact lung compliance and intra-pulmonary shunt.
- Conditions
- Critical Illness, Acute Respiratory Failure, Adult Syndrome
- Trial name
- NCT02160561
- Testing
- Intervention Arm
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Wake Forest University Health Sciences
ICU Stay & Mortality
Observational, Prospective, Single-center Study: Should Body Mass Index (BMI) be Added to the Scoring Criteria of Hepatic Critically Ill Patients in Intensive Care Unit??
The purpose of the study is to evaluate the hypothesis of poor clinical outcomes in critically ill patients that are having abnormal BMI.
- Trial name
- NCT03461523
- Where
- Egypt
- Volunteers
- 517 people, healthy volunteers welcome
- Sponsor
- National Hepatology & Tropical Medicine Research Institute
Sepsis, Critical Illness
Assessment of the Anti-inflammatory Effect of Heparin Infusion Versus Subcutaneous Injection in Septic Patients
Venous thromboembolism (VTE), including pulmonary embolism (PE) and deep venous thrombosis (DVT), is a common and severe complication of critical illness.
- Trial name
- NCT04313790
- Testing
- Heparin Infusion, subcutaneous heparin
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Damanhour University
Pims-Ts
PIMS-TS in Intensive Care: Retrospective Cohort Trial
Pediatric Multisystem Inflammatory Syndrome Temporally associated with SARS-CoV-2, (PMIS-TS) represents the new unit, partially imitating the previously described Kawasaki disease.
- Trial name
- PIMS-TS INT (NCT05388396)
- Testing
- PIMS-TS diagnostic a treatment
- Where
- Czechia
- Volunteers
- 180 people
- Sponsor
- Brno University Hospital
Oliguria
Effect of Implementing Emergency Nursing Protocol About Oliguria and Anuria on Patients' Outcomes
This study is aim to evaluate the effect of implementing emergency nursing protocol of obstructive anuria and oliguria on critically ill patients' outcomes.
- Trial name
- NCT06042868
- Testing
- Nursing protocol
- Volunteers
- 60 people
- Sponsor
- Hager AbdelNasser Hussein
Critical Illness, Pneumonia, Viral
Comparison Between Different Doses of Steroids in COVID-19 Patients
aim of this study is to compare between standard dose methyl prednisolone and mega dose methyl prednisolone as regards outcome reflected by mortality rate, percentage of mechanically ventilated patients and icu length of stay of…
- Trial name
- COVID-19 (NCT05279482)
- Testing
- observation for outcome of methylprednisolone dose
- Where
- 2 sites in Egypt
- Volunteers
- 104 people
- Sponsor
- Ain Shams University
Stress Disorders, Post-Traumatic, Anxiety
Diaries for Critically Ill Patients Written by Relatives
This study will investigate the effect of diaries written by relatives for critically ill patients on the risk of posttraumatic stress symptoms.
- Conditions
- Stress Disorders, Post-Traumatic, Anxiety, Depression
- Trial name
- NCT02357680
- Testing
- Diary
- Where
- 2 sites in Denmark
- Volunteers
- 189 people
- Sponsor
- Hospitalsenheden Vest
Pulmonary Embolism, Deep Vein Thrombosis
Angel® Catheter Early Feasibility Clinical Study
The primary objective of this clinical trial is to obtain initial insights into the safety of the Angel® Catheter in critically ill subjects with high risk of venous thromboembolism (VTE) disease AND who are not receiving…
- Conditions
- Pulmonary Embolism, Deep Vein Thrombosis, Venous Thromboembolism
- Trial name
- NCT01847196
- Testing
- Angel® Catheter
- Where
- 4 sites in United States
- Volunteers
- 6 people
- Sponsor
- BiO2 Medical
Atrial Fibrillation New Onset
Use of Red Cell Distribution Width for Prediction of New-onset Atrial Fibrillation in Critically Ill Sepsis Patients
Red cell distribution width variations are increased in a variety of medical conditions such as congestive heart failure, acute myocardial infarction, pulmonary embolism, pneumonia, critical illness, and cardiac arrest , and is a…
- Trial name
- NCT03523676
- Testing
- Red Cell Distribution Width
- Volunteers
- 70 people
- Sponsor
- Ain Shams University
Mechanical Ventilation, Critical Illness
Neuromuscular Electrical Stimulation in a Patient on Invasive Mechanical Ventilation (MOVCARE)
This clinical study aims to compare the effects of conventional physical therapy alone versus conventional physical therapy combined with neuromuscular electrical stimulation (NMES) in patients admitted to the ICU and undergoing…
- Conditions
- Mechanical Ventilation, Critical Illness, Intensive Care Unit Patients, Muscle Weakness Condition
- Trial name
- MOVCARE (NCT07188350)
- Testing
- Conventional Physical Therapy, Neuromuscular Electrical Stimulation (NMES)
- Where
- Brazil
- Volunteers
- 150 people
- Sponsor
- Hospital Moinhos de Vento
Mechanical Ventilation
The Geniohyoid Muscle in Critical Illness
Many patients lose muscle due to being unwell in an intensive care unit. This muscle loss can lead to weakness of the arms and legs when they leave the unit, and when they go home.
- Trial name
- NCT07606690
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Warrington Hospital
Stress Hyperglycemia
Incidence and Course of Stress Hyperglycemia in Critically Ill Children Admitted to PICU of Assiut University Children Hospital
Detection of the prevelance of stress hyperglycemia in patients admitted to pediatric intensive care unit of Assiut university children hospital , asses its pattern ,course ,risk factors, its relation to the outcome and its…
- Trial name
- NCT04591561
- Volunteers
- 100 people
- Sponsor
- Assiut University
Transthoracic Echocardiography
Reliability of Ultrasound Examination of the Inferior Caval Vein
The purpose of this study is to compare validity of examination and measurement of inferior caval vein from different views in critically ill patients on mechanical ventilation.
- Trial name
- NCT04488627
- Testing
- Conventional transthoracic echocardiographic examination at the intensive care unit.
- Where
- Czechia
- Volunteers
- 100 people
- Sponsor
- Emergency Medical Service of the Central Bohemian Region, Czech Republic
Mortality
Effectness of Treatment With Mechanical Insufflation-Exsufflation
Patients defined with impaired cough function as maximum expiratory pressure (MEP) < 60cmH2O. Collected the patients in our surgical ICU who are able to reach 6-8CC/IBW under pressure support mode for 24 hours and MEP < 60cmH2O.
- Trial name
- NCT04149873
- Testing
- MIE
- Where
- Taiwan
- Volunteers
- 240 people
- Sponsor
- Chimei Medical Center
Systemic Inflammation
Influence of In-line Microfilters on Systemic Inflammation in Adult Critically Ill Patients
Studies showed that infusion or injection of drugs and fluids results in introduction of microparticles into the bloodstream. These microparticles may cause organ damage and stimulate the immune system thus aggravating the…
- Trial name
- NCT01534390
- Testing
- In-line microfilter (Supor IV Filter; Pall Corporation, Port Washington, New York)
- Where
- Austria
- Volunteers
- 504 people
- Sponsor
- University of Salzburg
Renal Function, Critical Illness
Evaluation of the Optimal Technique for Determination of Renal Function of Critically Ill Patients
The purpose of this study is to evaluate the optimal technique for determination of the renal function of critically ill patients.
- Trial name
- NCT00117390
- Testing
- Measurement of inulin clearance
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- University Hospital, Ghent
Critical Illness
Predictive Value of Heart Rate Variability on Outcome in Patients Admitted to the Intensive Care Department
This study is designed to evaluate the predictive value of heart rate variability on medial outcome in patients admitted to the intensive care department
- Trial name
- NCT02892669
- Testing
- non interventional study
- Volunteers
- 300 people
- Sponsor
- Rambam Health Care Campus
Acute Kidney Injury
PREVENTion With Sglt-2 Inhibition of Acute Kidney Injury in Intensive Care
Background Acute Kidney Injury (AKI) is a potentially life-threatening condition caused by unsafe levels of fluid and waste products accumulating in the body.
- Trial name
- PREVENTS-AKI (NCT05468203)
- Testing
- Dapagliflozin 10mg Tab
- Where
- 3 sites in Australia
- Volunteers
- 51 people
- Sponsor
- The George Institute
Metabolic Acidosis, Critical Illness
The Threshold of Serum Anion Gap as a Screening Tool for Organic Acidosis
Background: The serum anion gap (AG) is commonly used as a screening tool for acid-base disorders. With modern laboratory techniques using ion-selective electrodes to measure the main electrolyte components of the AG, our…
- Conditions
- Metabolic Acidosis, Critical Illness, Anion Gap Acidosis, Lactic Acidosis
- Trial name
- NCT04975906
- Where
- Singapore
- Volunteers
- 16,475 people
- Sponsor
- Changi General Hospital
COVID-19, Respiratory Failure
Compartmental Inflammation in Mechanically Ventilated Patients With COVID-19
The aim of the present study is to examine the inflammatory response in the pulmonary compartment and blood of critically ill patients admitted to the ICU with COVID-19.
- Trial name
- COV2ICU-DK (NCT04354584)
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Hvidovre University Hospital
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