Clinical trials: Illness, Critical
Critical Illness
Understanding the Impact of Critical Illness on Falls Risk - a 12 Month Observational Study
Understanding the Impact of Critical Illness on Falls Risk - a 12 Month Observational Study
- Trial name
- NCT03141762
- Where
- 2 sites in United States, Australia
- Volunteers
- 100 people
- Sponsor
- University of Melbourne
Critically Ill, Muscular Atrophy
Non-sedation Versus Sedation With a Daily Wake-up Trial in Critically Ill Patients Receiving Mechanical Ventilation - Effects on Physical Function
Critically ill, ventilator-treated patients rapidly loose much of their muscle mass and strength. This can attribute to prolonged admission, prolonged mechanical ventilation, increased mortality and might have a negative impact…
- Trial name
- NCT02034942
- Testing
- Non-sedation, Sedation, control
- Where
- Denmark
- Volunteers
- 205 people
- Sponsor
- Palle Toft
Critical Illness With or Without Sepsis
TRanscriptomic Analysis of Circulating Endothelial Cells During Sepsis - TRACES Study
Vascular dysfunction is an important mechanism involved in organ failure, in the setting of sepsis condition, with different types of circulating endothelial cells.Transcriptom analysis via RNAseq in different types of…
- Trial name
- TRACES (NCT04841824)
- Testing
- Observational study
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Critical Illness
Validation of Prediction Model of Vitamin D Deficiency
Many studies have pointed out that patients with vitamin D deficiency have a longer stay in the intensive care unit and a poor prognosis.
- Trial name
- NCT05094388
- Testing
- Admitted to intensive care units
- Where
- Taiwan
- Volunteers
- 400 people
- Sponsor
- National Taiwan University Hospital
Respiratory Failure, Hypoxemia
Application of Indicator Based-electrical Impedance Tomography Method Assess Lung Regional Perfusion in ICU Patients
This study is an observational study. Investigate the relationship of oxgenation and lung regional ventilation and perfusion assessed by the indicator based-EIT method in the critically ill patients in ICU
- Conditions
- Respiratory Failure, Hypoxemia, ARDS, Human
- Trial name
- NCT04081142
- Where
- China
- Volunteers
- 119 people
- Sponsor
- Yun Long
Critical Illness, Nutritional Deficiency
Trace Element Repletion Following Severe Burn Injury
Major burn patients are characterized by large exudative losses of Cu, Se and Zn. Trace element (TE) repletion has been shown to improve clinical outcome.
- Conditions
- Critical Illness, Nutritional Deficiency, Trace Element Deficiency, Burn Injury
- Trial name
- NCT03204669
- Testing
- Trace elements replacement
- Where
- Switzerland
- Volunteers
- 139 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Acute Kidney Injury
Outcomes of Acute Kidney Injury in Critically Ill Patients
this study to evaluate the frequency of acute kidney injury in critically ill patients in intensive care units.
- Trial name
- NCT03338127
- Testing
- renal function test
- Volunteers
- 40 people
- Sponsor
- Alaa H Fahmy
Critically Ill, Intensive Care Unit
PERFormance Enhancement of the Canadian Nutrition Guidelines by a Tailored Implementation Strategy: The PERFECTIS Study
Canadian Critical Care Nutrition Guidelines assist health practitioners in identifying best practices for feeding critically ill patients.
- Trial name
- PERFECTIS (NCT01168128)
- Testing
- Tailored Change Strategy
- Where
- 5 sites in United States, Canada
- Volunteers
- 278 people
- Sponsor
- Daren K. Heyland
Renal Replacement Therapy for Acute Kidney Injury in ICU, Continuous Renal Replacement Therapy (CRRT)
Continuous Renal Replacement Therapy Doses in Critically Ill Patients With Acute Kidney Injury
Acute kidney injury in critically ill patients admitted to the ICU is a common complication associated with high mortality or long-term chronic kidney damage.
- Trial name
- CRRIT1 (NCT06901011)
- Testing
- continuous renal replacement therapy
- Volunteers
- 100 people
- Sponsor
- Fundacion Clinic per a la Recerca Biomédica
Adrenal Insufficiency
Adrenal Function in Critical Illness
An appropriate hypothalamic-pituitary-adrenal (HPA) axis response is required to survive critical illness. Primary adrenal insufficiency, relative adrenal insufficiency, tissue resistance to glucocorticoids, ACTH deficiency and…
- Trial name
- NCT00156767
- Where
- United States
- Volunteers
- 225 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Tracheostomy Complication, Critical Illness
PUSH-IT Continuing Enteral Feeds for Tracheostomy
The goal of this clinical trial is to evaluate nutrition administration in the time around the tracheostomy in patients with breathing tubes.
- Conditions
- Tracheostomy Complication, Critical Illness, Nutritional Deficiency
- Trial name
- NCT05906472
- Testing
- Feeds continued, Feeds held
- Where
- 6 sites in United States
- Volunteers
- 200 people
- Sponsor
- State University of New York at Buffalo
Injury of Diaphragm, Mechanical Ventilation Complication
Using Ultrasound to Study Respiratory Muscle Function in Critically Ill Patients
Mechanical ventilation can be life saving strategy for patients with respiratory failure due to a variety of reasons. Once the underlying illness has resolved, intensive care doctors have to take a decision on when the patient is…
- Conditions
- Injury of Diaphragm, Mechanical Ventilation Complication, Critical Illness
- Trial name
- NCT03139695
- Testing
- Ultrasound
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Delirium
Pilot Clinical Trial of an Integrative Intervention to Improve Critically Ill Patients' Delirium and Related Outcomes
Methodology: Pilot randomized controlled trial with 1 intervention and 1 parallel standard care group to assess the feasibility and treatment effect of a multimodal integrative intervention for delirium prevention and associated…
- Trial name
- REPOSE (NCT02905812)
- Testing
- RGI & Massage
- Where
- Canada
- Volunteers
- 27 people
- Sponsor
- University of Alberta
Trauma, Critical Illness
Enteral Glutamine Supplementation for the Patient With Major Torso Trauma
Glutamine is considered a conditionally essential amino acid during critical illness. After severe trauma, glutamine supplementation into the gastrointestinal tract may help maintain bowel function.
- Conditions
- Trauma, Critical Illness, Shock
- Trial name
- NCT00178581
- Testing
- Glutamine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- The University of Texas Health Science Center, Houston
Critical Illness Polyneuromyopathy (CIPNM), ICU Acquired Weakness (ICUAW)
Electrical Muscle Stimulation (EMS), a Preventive and Therapeutic Tool for Critical Illness Polyneuromyopathy (CIPNM)
The purpose of this study is to investigate the role of EMS as a preventive and therapeutic tool of CIPNM. The investigators hypothesized that EMS will prevent the development of CIPNM or have a beneficial role as a therapeutic…
- Trial name
- NCT00882830
- Testing
- EMS
- Where
- Greece
- Volunteers
- 52 people
- Sponsor
- University of Athens
Glucose Metabolism Disorders, Critical Illness
Effect of Location of Feeding on Glycemic Control in Critically Ill Patients (ELF)
The purpose of this study is to investigate the effect of location of feeding on glycemic control in critically ill patients. The investigators hypothesize that glycemic control in critically ill patients who receive enteral…
- Trial name
- ELF (NCT03566992)
- Testing
- Gastric
- Where
- United States
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Winchester Medical Center
Acute Respiratory Distress Syndrome (ARDS)
Surviving ARDS: The Influence of Quality of Care and Individual Patient Characteristics on Quality of Life
The purpose of the DACAPO study ("Surviving ARDS: the influence of quality of care and individual patient characteristics on quality of life") is to investigate the role of quality of care and individual patient characteristics…
- Trial name
- DACAPO (NCT02637011)
- Where
- 3 sites in Germany
- Volunteers
- 2,000 people
- Sponsor
- University Hospital Regensburg
Communication, Critical Illness
Improving Family Meetings in the Pediatric Cardiac Intensive Care Unit
This study aims to improve communication between medical teams, patients, and families in the pediatric cardiac intensive care unit.
- Trial name
- NCT03749330
- Testing
- CICU Team And Loved Ones Communicating (CICU TALC)
- Where
- United States
- Volunteers
- 451 people
- Sponsor
- Children's Hospital of Philadelphia
Acute Kidney Injury, ARDS, Human
Renal Doppler to Predict Acute Kidney Injury (AKI) in ARDS Patients. (RED-AKI Study)
This is a multicenter international observational prospective cohort study. The main questions it aims to answer are: PRIMARY AIM: To describe the capability of IRVF demodulation at diagnosis of ARDS to predict development of AKI…
- Trial name
- RED-AKI (NCT06302192)
- Testing
- ARDS+AKI
- Volunteers
- 164 people
- Sponsor
- Policlinico Hospital
Critical Illness, Neuropathy
Establishing Normative Data for Pupillometer Assessments in Neuro-Intensive Care
The purpose of this study is to collect a large amount of data that may assist in addressing the gap in knowledge of understanding pupillometer readings using a pupillometer device.
- Trial name
- ENDPANIC (NCT02804438)
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- University of Texas Southwestern Medical Center
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.