Clinical trials: Image Enhancement
Coronary Artery Disease
Gadobutrol/Gadavist-enhanced Cardiac Magnetic Resonance Imaging (CMRI) to Detect Coronary Artery Disease (CAD)
Participants being evaluated for suspected or known Coronary artery Disease (CAD) based on signs and/or symptoms, will be invited to participate in the study.
- Trial name
- GadaCAD 1 (NCT01890421)
- Testing
- Gadobutrol (Gadovist, Gadavist, BAY86-4875)
- Where
- 23 sites in United States, France and 5 more
- Volunteers
- 426 people
- Sponsor
- Bayer
Prostate Cancer
Threedimensional Multiparametric Ultrasound for Prostate Cancer Detection
Rationale: Current imaging techniques for the detection and grading of prostate cancer are imperfect, leading to unnecessary biopsies, suboptimal treatment decisions and missed clinically significant cancers.
- Trial name
- 3DmpUS for PCa (NCT04605276)
- Testing
- No intervention
- Where
- 3 sites in Netherlands
- Volunteers
- 608 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Cataract, Retina Disorder
A Big Data-based Cohort Study for Cataract Patients
Cataract is an important cause of blindness and visual impairment worldwide. At present, the only effective treatment method is surgery.
- Trial name
- NCT05491798
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Sun Yat-sen University
Colonic Adenoma, Colonoscopy
Blue Laser Imaging and White Light Imaging Colonic Polyps
The adenoma detection rate by colonoscopy for asymptomatic individuals aged 50 years and older is estimated to be at least 25%. It is known that during colonoscopy, lesions may be missed.
- Trial name
- NCT03421600
- Testing
- blue laser imaging, White light imaging
- Where
- Singapore
- Volunteers
- 184 people
- Sponsor
- Changi General Hospital
MRI, MRI Image Enhancement
Optimizing Liver MRI Using Breath-Holding With and Without Oxygen
The goal of this interventional study (clinical trial) is to learn if different breath-holding techniques, with and without extra oxygen, can improve the quality of abdominal Magnetic Resonance Imaging (MRI) images in healthy…
- Trial name
- NCT07135401
- Testing
- Breath-hold conditions
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Magnetic Resonance Imaging, Image Enhancement
Drug Use Investigation of Gadovist.
The objectives of this study are to investigate the safety and effectiveness of Gadovist.
- Trial name
- NCT02540967
- Testing
- Gadobutrol (Gadavist/Gadovist, BAY86-4875)
- Where
- Japan
- Volunteers
- 3,357 people
- Sponsor
- Bayer
MRI Image Enhancement
Development of Protocols and Methods for Image Processing and Enhancement of Magnetic Resonance Imaging (MRI) Data.
The purpose of the study is to develop new methods for image processing and enhancement of MRI data. Different setting of acquisition parameters used in conventional clinical MRI protocols will be defined, to create "New…
- Trial name
- NCT04942704
- Testing
- Non interventional Imaging - MRI
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Medic Vision Imaging Solutions Ltd
Liver Cirrhosis, Carcinoma, Hepatocellular
Gadoxetic Acid-enhanced MR Evaluation of Hepatocellular Carcinoma and Dysplastic Nodules in the Cirrhotic Liver
A prospective intra-individual study to investigate the diagnostic performance of gadoxetic acid-enhanced MR for the patients with liver cirrhosis using thin-section whole-explant as standard of reference
- Trial name
- PriMPa (NCT01501240)
- Where
- 2 sites in South Korea
- Sponsor
- Jae Ho Byun
Body Image, Physical Activity
SDT-Based Intervention for Exercise Motivation in Female Students
Physical inactivity, maladaptive exercise motives, and body image concerns are highly prevalent among young adult women and are associated with reduced psychological well-being and increased risk for disordered eating.
- Trial name
- No acronym use (NCT07506343)
- Testing
- Experimental group will receive a face-to-face psychoeducational program grounded in Self-Determination Theory. Control group will no receive any psychoeducational program
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- Universidad Francisco de Vitoria
Ischemic Heart Disease
Dose Optimization for Rubidium PET Imaging in Patients With Known or Suspected Ischemic Heart Disease
Selection of the appropriate administered activity for each patient's body habitus is very important to obtain diagnostic image quality.
- Trial name
- RUBY-DOSE (NCT05037799)
- Testing
- Rb-82 Radioisotope
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Left Atrial Fibrosis
Validation of the Efficacy of the Tool GIMIAS® for the Assessment of Left Atrial Fibrosis in a Group of Healthy Volunteers (RESTORE-HV)
The purpose of this study is to validate the technique for the detection of left atrial fibrosis through segmentation of endocardial and epicardium landmarks of the images obtained with 3 Tgadobutrol-enhanced magnetic resonance…
- Trial name
- RESTORE-HV (NCT02274246)
- Testing
- gadobutrol
- Where
- Spain
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Fundacion Clinic per a la Recerca Biomédica
Prostate Cancer
Image-guided, Tumor-focused Radiotherapy Treatment in Intermediate and High-risk Prostate Cancer
This is a phase II non-blinded randomized controlled trial of image-guided, tumor-focused radiotherapy in patients with intermediate- or high-risk prostate cancer planning to undergo definitive radiotherapy with or without…
- Trial name
- RadTARGET (NCT06990542)
- Testing
- Image-guided tumor-focused radiation therapy
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of California, San Diego
Hepatic Malignant Tumors, Hepatic Perfusion Disorders
Correlation Between CEUS Identification of Nodular HPD on CE-MRI and Hepatic Malignant Lesions
Hepatic malignant tumors are a category of diseases with high incidence and mortality rates worldwide, including various types such as primary hepatocellular carcinoma (HCC), intrahepatic cholangiocarcinoma (ICC), and liver…
- Trial name
- NCT06816212
- Where
- China
- Volunteers
- 280 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Coronary Artery Disease
Gadobutrol / Gadavist-enhanced Cardiac Magnetic Resonance Imaging (CMRI) to Detect Coronary Artery Disease (CAD)
Subjects being evaluated for suspected or known Coronary artery Disease (CAD) based on signs and/or symptoms, will be invited to participate in the study.
- Trial name
- GadaCAD 2 (NCT01890434)
- Testing
- Gadobutrol (Gadavist, Gadovist, BAY86-4875)
- Where
- 24 sites in United States, Australia and 2 more
- Volunteers
- 478 people
- Sponsor
- Bayer
Contrast Agent, Medical Imaging Data
ELUDYN: Assessment of Intra-individual Variability of Vascular Dynamics of Gadopiclenol Injection Parameters in Contrast-enhanced MRI
This study aims to understand how the volumes and speeds of intravenous injection of a recent type of contrast agent can be optimized in order to improve the information provided by medical images.
- Conditions
- Contrast Agent, Medical Imaging Data, MRI Image Enhancement
- Trial name
- ELUDYN (NCT07346131)
- Testing
- contrast agent, Gadolinium
- Where
- Switzerland
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Hôpital Fribourgeois
Cancer, Prostate Cancer
Artificial Intelligence (AI)-Enhanced Pretreatment Peer-review Process to Improve Patient Safety in Radiation Oncology
This prospective study will test artificial intelligence (AI) and machine learning (ML) decision support tools. This tool is designed to help doctors, physicists and other staff during pre-treatment peer review, a step where…
- Trial name
- NCT07463833
- Testing
- The Artificial Intelligence (AI)/ Machine Learning (ML) contribution to treatment planning
- Where
- United States
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Carcinoma, Glioblastoma
MRinRT: Swansea University and SWWCC Collaboration Study.
The aim of this study is to learn whether using MRI (magnetic resonance imaging) scans to plan radiotherapy is better than using CT (computed tomography) scans alone.
- Conditions
- Carcinoma, Glioblastoma, Radiotherapy, MRI
- Trial name
- MRinRT (NCT07365124)
- Testing
- MRI
- Where
- United Kingdom
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Swansea Bay University Health Board
High Grade Glioma
Study of Convection-Enhanced, Image-Assisted Delivery of Liposomal-Irinotecan In Recurrent High Grade Glioma
This is a single center, dose-toleration study designed to investigate and determine the maximum tolerated dose of nanoliposomal irinotecan in adults with recurrent high-grade glioma when administered directly into the tumor…
- Trial name
- NCT02022644
- Testing
- nanoliposomal irinotecan
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of California, San Francisco
HCC
"Double Low-Dose" DECT for HCC Imaging
Hypothesis: double low-dose protocol provide better lesion conspicuity than standard protocol CT in patients at high-risk of HCC.
- Trial name
- NCT03045445
- Testing
- Double Low-Dose protocol CT, Standard protocol CT
- Where
- South Korea
- Volunteers
- 68 people
- Sponsor
- Seoul National University Hospital
Colorectal Neoplasm, Hepatic Neoplasm
Metastatic Colorectal Cancer: Treatment Response With Dynamic Contrast MRI
The objectives for this study include: Testing a unique way of imaging people with colorectal cancer and other cancers that has spread to the liver using magnetic resonance imaging (MRI); Seeing if the MRI process can be used…
- Trial name
- NCT00820456
- Testing
- DCE-MRI
- Where
- 5 sites in United States
- Volunteers
- 6 people
- Sponsor
- American College of Radiology