Clinical trials: Image Guidance
Hypertrophic Cardiomyopathy (HCM), Cardiac Imaging
ENABLE-HCM - AI-ENabled Echocardiography With Ultrasound Beyond the Echo Lab for Better HCM Imaging and Expanded Access
This study evaluates whether healthcare providers without specialized ultrasound training can use UltraSight's machine learning based Guidance Software to perform limited transthoracic echocardiography in patients with…
- Conditions
- Hypertrophic Cardiomyopathy (HCM), Cardiac Imaging, Echocardiography, Mavacamten
- Trial name
- NCT07155434
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- UltraSight
Thoracic Spine Neoplasm
Safety of MRI Compatible Hardware for MRI-based Image Guidance During Spine Surgery
This trial investigates the safety and accuracy of using 2 pieces of hardware (a clamp and a needle) that are able to be used with magnetic resonance imaging (MRI) during spinal surgery.
- Trial name
- NCT04563806
- Testing
- Magnetic Resonance Imaging, Therapeutic Conventional Surgery
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- M.D. Anderson Cancer Center
Vascular Malformations
Stereotactic MRI Based Image Guidance for the Treatment of Vascular Malformations - a Pilot Study
Treatment of vascular malformations requires the placement of a needle within anatomically non well defined, pathological vessels, which may be as small as 1 mm, with the current state of the art relying exclusively on two…
- Trial name
- SIGVaM (NCT02991352)
- Testing
- Image guided needle placement
- Where
- 3 sites in Switzerland
- Volunteers
- 10 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Pelvic Malignancies
Testing a WearabLE Artificial Intelligence-POwered Device For OPtimal DAily RaDiation Therapy Using Image Guidance
This is a device feasibility study to determine the feasibility of automatically predicting time to treatment readiness using a wearable imaging device (Fullyet) in both healthy volunteers and patients with pelvic malignancies…
- Trial name
- LEOPARD-IG (NCT06820385)
- Testing
- Fullyet Device and CT Scans, Fullyet Device and MRI Scans
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Chronic Limb-Threatening Ischemia
IVUS Guidance in BTK Interventions
Chronic limb-threatening ischemia (CLTI) is a severe form of peripheral artery disease in which very poor blood flow in the arteries below the knee can cause rest pain, non-healing wounds, and even loss of the limb.
- Trial name
- IMAGE-BTK (NCT07731997)
- Testing
- Intravascular ultrasound-guided EVT, Angiography-guided EVT
- Where
- 4 sites in Taiwan
- Volunteers
- 212 people
- Sponsor
- Shin Kong Wu Ho-Su Memorial Hospital
Systolic Heart Failure, Dysynchrony
Imaging Study of Allocation of Pacing Targets in Cardiac Resynchronization Therapy
This randomized controlled trial will assess a cardiac MRI derived 4D digital cardiac model to optimized left and right ventricular lead delivery to improve response to cardiac resynchronization therapy.
- Conditions
- Systolic Heart Failure, Dysynchrony, Image Guidance, Digital Twins
- Trial name
- NCT01640769
- Testing
- 4D Model guided delivery of cardiac pacing leads, Standard CRT lead delivery
- Where
- 5 sites in Canada
- Volunteers
- 210 people
- Sponsor
- Libin Cardiovascular Institute of Alberta
Lung Cancer
Image Guided and Breathing Adapted Radiotherapy of Early Stage Lung Cancer
The purpose of this study is to quantify the variation in tumour middle position during a course of stereotactic body radiotherapy (SBRT), and thereby be able to design radiotherapy margins that takes into account the full motion…
- Trial name
- NCT00910546
- Testing
- visicoil gold marker 0.7 x 20 mm
- Where
- Denmark
- Volunteers
- 15 people
- Sponsor
- Gitte Fredberg Persson
Lung Cancer, Thoracic Cancer
Validate the Safety and Feasibility of the CT-guided Interventional Robot in Percutaneous Lung Cryablation Procedures
This study aims to investigate whether the interventional robot can be well and safely used for percutaneous lung cryoablation in patients with lung cancer.
- Trial name
- NCT06581107
- Testing
- CT-fluoroscopy guided master-slave intervetional robot-assisted lung Cryoablation
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Liver Cancer (Primary and Metastatic), Lung Cancer (Diagnosis)
Registry of Minimally Invasive Cancer Treatment Using Spectral Angio-CT Image Guidance
This study collects data from patients undergoing minimally invasive, image-guided cancer treatments at participating hospitals in the Netherlands and France.
- Conditions
- Liver Cancer (Primary and Metastatic), Lung Cancer (Diagnosis), Bone Cancer Metastatic, Bone Cancer Tumor
- Trial name
- PreciseOnco (NCT07636148)
- Where
- 3 sites in France, Netherlands
- Volunteers
- 2,000 people
- Sponsor
- Mark C Burgmans, MD PhD
Prostate Cancer, Post-Prostatectomy
Evaluation Of Transperineal Ultrasound For Image Guidance In The Treatment Of Prostate Cancer in Men Following Prostatectomy
This study is being done to find out if transperineal ultrasound (TPUS) can help define the prostate bed for radiation treatment planning and improve upon current methods of image guidance for the treatment of prostate cancer.
- Trial name
- NCT02110667
- Testing
- Transperineal Ultrasound
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Vermont Medical Center
Prostate Cancer
Short-course Hypofractionated Radiotherapy for Localized Prostate Cancer
This study is aimed at providing further clinical evidence to support or refute the current understanding of biological sensitivity of prostate cancer to fractionated radiotherapy.
- Trial name
- NCT00126165
- Testing
- radiotherapy
- Where
- Canada
- Volunteers
- 72 people
- Sponsor
- Alberta Health services
Localized Prostate Adenocarcinoma, Stage I Prostate Cancer AJCC v8
Image-Guidance and Online Adaptation With Stereotactic Body Radiation Therapy for the Treatment of Localized Prostate Cancer, MANTICORE Trial
This clinical trial studies the side effects of image-guidance and online adaptation with stereotactic body radiation therapy (SBRT) for the treatment of patients with prostate adenocarcinoma that has not spread to other parts of…
- Conditions
- Localized Prostate Adenocarcinoma, Stage I Prostate Cancer AJCC v8, Stage II Prostate Cancer AJCC v8, Stage III Prostate Cancer AJCC v8
- Trial name
- NCT07276438
- Testing
- Biospecimen Collection, Computed Tomography, CT-guided Stereotactic Body Radiation Therapy
- Where
- United States
- Volunteers
- 186 people
- Sponsor
- Jonsson Comprehensive Cancer Center
External Ventricular Drain (EVD), Image Guidance
Image Guided EVD Placement
To determine if use of the Stryker Nav3 image guidance system offers superior results in external ventricular drain (EVD) placement compared to the standard free-hand technique.
- Trial name
- NCT05639036
- Testing
- Image Guided External Ventricular Drain Placement Using the NAV3 System, Free Hand External Ventricular Drain Placement
- Where
- Canada
- Sponsor
- Hamilton Health Sciences Corporation
Cancer
Nano-X Image Guidance: CBCT With Gravity-induced Motion
A pilot stage, device feasibility trial, to investigate the feasibility of acquiring cone beam computed tomography (CBCT) images for image guidance for radiation therapy by maintaining a fixed imaging system and rotating the…
- Trial name
- Nano-X IG (NCT04488224)
- Testing
- Nano-X Patient Rotation System, Conventional CBCT scan, Psychometrically validated questionnaires
- Sponsor
- University of Sydney
Radiation Injuries
Novel Wireless Mixed Reality Headset for Image Guidance in Cardiac Catheterization Laboratory
Our hypothesis is that improved line of sight to patient data, ergonomics, and headset lead shielding in the CCL will lead to behavioral changes in the CCL personnel that will reduce radiation exposure to all members of the team.
- Trial name
- MRCCL (NCT05063773)
- Testing
- Mixed reality heads up display
- Volunteers
- 150 people
- Sponsor
- SG Devices LLC
Pediatric Cancer
Estimating Setup Uncertainty in Pediatric Proton Therapy Using Volumetric Images
This research study establishes a repository for imaging data generated during image-guided proton therapy for various pediatric cancers.
- Trial name
- NCT04125095
- Where
- United States
- Volunteers
- 367 people
- Sponsor
- St. Jude Children's Research Hospital
Posttraumatic Stress Disorder
Multimodal Image Analysis and Guidance of Neuromodulation for Trauma-Related Symptoms
MAGNETS is a prospective, randomized, parallel-design, sham-controlled clinical trial of accelerated, functional magnetic resonance imaging (fMRI)-guided intermittent theta burst stimulation (iTBS) to the right dorsolateral…
- Trial name
- MAGNETS (NCT06449326)
- Testing
- Active Intermittent theta burst stimulation
- Where
- 2 sites in United States
- Volunteers
- 64 people
- Sponsor
- University of New Mexico
Magnetic Resonance Imaging
MR Guidance for Liver and Pancreas
This is a single centre, single arm, prospective feasibility study that aims to see whether magnetic resonance imaging (MRI) as a source of image guidance before each radiation treatment fraction is feasible, and also if it may…
- Trial name
- NCT03582189
- Testing
- MRI
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University Health Network, Toronto
CT Guided Biopsy, CT Guided Drain Placement Within the Abdomen or Pelvis
Ultrasound-CT Fusion System for Interventional Radiology Procedures
The objective of this research is to use the Clear Guide SCENERGY technology, an FDA approved Ultrasound-CT fusion imaging system, that allows the user to fuse CT images onto a real-time ultrasound that is being performed on the…
- Conditions
- CT Guided Biopsy, CT Guided Drain Placement Within the Abdomen or Pelvis, CT Guided Injection of Muscle or Nerve Within the Pelvis
- Trial name
- NCT03226535
- Testing
- Ultrasound-CT Fusion
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Clear Guide Medical
Renal Tumor, Renal Cancer
A CCafU-UroCCR Randomized Trial: 3D Image-Guided Robot-AssisTEd Partial Nephrectomy for Renal Complex Tumor (UroCCR N°99)
The goal of this clinical trial is to evaluate peri and post-operative outcomes as well as long-term survival of 3D IGRAPN compared to conventional Robot-Assisted Partial Nephrectomy (RAPN) for moderate and highly complex renal…
- Trial name
- ACCURATE (NCT05572216)
- Testing
- Robot assisted partial nephrectomy with 3D image guidance
- Where
- 2 sites in France
- Volunteers
- 694 people
- Sponsor
- University Hospital, Grenoble