Clinical trials: Image Reconstruction
Brest Cancer
Creation and Implementation a Method for Breast Reconstruction After Radical Surgery Using Decellularized Xenomatrix in Combination With Lymphovenous Anastomosis in Breast Cancer.
In 2020, more than 31,000 new cancer cases were reported in Kazakhstan, with breast cancer being the most common type, accounting for more than 4,200 new cases.
- Trial name
- NCT07782801
- Testing
- Radical mastectomy with axillary lymph node dissection, Immediate implant-based breast reconstruction, Acellular xenogeneic matrix (AXM)
- Where
- Kazakhstan
- Volunteers
- 60 people
- Sponsor
- National Research Oncology and Transplantology Center, Kazakhstan
Benign or Malignant Tumour of the Oral Cavity, Stage III-IV Osteonecrosis
Validation of the O-bridge Protocol: a Prospective, Multicenter Trial
Surgical reconstruction to restore oral function and aesthetics after major ablative surgery in the oral cavity forms a challenge to maxillofacial surgeons, and greatly impacts patient' quality of life (QOL).
- Conditions
- Benign or Malignant Tumour of the Oral Cavity, Stage III-IV Osteonecrosis, Mandibular Reconstruction, Fixed Dental Restoration
- Trial name
- NCT04007783
- Where
- 5 sites in Belgium
- Volunteers
- 80 people
- Sponsor
- AZ Sint-Jan AV
Anterior Cruciate Ligament Rupture, Quadriceps Muscle Atrophy
Blood Flow Restriction After Anterior Cruciate Ligament Reconstruction (ACLR)
Muscle strength and muscle volume decrease rapidly with the immobilization process after sports-related injury and surgery. Depending on the decrease in muscle strength and muscle volume, functional performance also deteriorates…
- Trial name
- ACLR (NCT05500872)
- Testing
- Cross-education and blood flow restriction training, Cross-education
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Hacettepe University
Breast Reconstruction
SERI® Surgical Scaffold Postmarket Study of Soft Tissue Support and Repair in Breast Reconstruction
Prospective, single center, postmarket clinical study to obtain clinical experience with the use of SERI® Surgical Scaffold for soft tissue support and repair in breast reconstruction.
- Trial name
- NCT01914653
- Testing
- Silk surgical mesh
- Where
- Israel
- Volunteers
- 17 people
- Sponsor
- Sofregen Medical, Inc.
LET, ACL Reconstruction
Long-term Follow up of the Stability 1 Trial
From 2014-2017, across 7 Canadian and 2 European sites, we randomized 618 patients at high-risk of re-injury, to anterior cruciate ligament reconstruction (ACLR) with or without a lateral extraarticular tenodesis (LET) and…
- Conditions
- LET, ACL Reconstruction, Osteoarthritis (OA) of the Knee
- Trial name
- STABILITY LTF (NCT06885372)
- Testing
- Lateral Extra-Articular Tenodesis (LET), ACL Reconstruction
- Where
- 8 sites in Canada, United Kingdom
- Volunteers
- 510 people
- Sponsor
- Western University, Canada
Safety and Performance, Breast Tissue Expander
Post-marketing Clinical Monitoring of Safety and Performance of Breast Tissue Expander for Breast Reconstruction
The study investigates the safety and performance of Silimed® brand breast tissue expander in women born with indication for breast reconstruction.
- Trial name
- STEPS-R (NCT06981481)
- Testing
- Breast tissue expander
- Where
- 3 sites in Brazil
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Silimed Industria de Implantes Ltda
Breast Cancer
SPY Intra-Operative Angiography & Skin Perfusion in Immediate Breast Reconstruction w/ Implants
The investigators hope to learn the value of the SPY ELITE® intra-operative angiography in reducing post-operative complications associated with low breast skin blood flow after breast reconstruction using implants.
- Trial name
- NCT01315119
- Testing
- SPY Intra-Operative Angiography
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Stanford University
Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Reconstruction
Donor Ankle Sensorimotor Recovery After ACL Reconstruction With a Peroneus Longus Tendon Autograft
This prospective longitudinal observational cohort study will characterize recovery of donor-ankle sensorimotor function in adults who have undergone primary anterior cruciate ligament reconstruction using a peroneus longus…
- Conditions
- Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Reconstruction, Donor Site Complication
- Trial name
- NCT07762989
- Testing
- Anterior Cruciate Ligament Reconstruction Using a Peroneus Longus Tendon Autograft
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Gazi University
Diaphragm Issues, Diaphragm; Paralysis, Due to Accidental Section of Phrenic Nerve During Procedure
A Chart Review to Evaluate the Safety and Efficacy of Phrenic Nerve Reconstruction for the Treatment of Diaphragmatic Paralysis
A retrospective chart review to evaluate the safety and efficacy of phrenic nerve reconstruction for diaphragmatic paralysis.
- Conditions
- Diaphragm Issues, Diaphragm; Paralysis, Due to Accidental Section of Phrenic Nerve During Procedure, Breath Shortness, Diaphragmatic Paralysis
- Trial name
- NCT06257589
- Where
- 2 sites in United States
- Volunteers
- 700 people
- Sponsor
- Advanced Reconstructive Surgery Alliance
Anterior Cruciate Ligament Reconstruction
Effectiveness of Kneehab in Strengthening Quadriceps in Rehabilitation Post Anterior Cruciate Ligament (ACL) Reconstruction
Prospective, controlled, randomized, single blind study in patients undergoing rehabilitation following anterior cruciate ligament reconstruction. 96 patients were randomly assigned to one of three groups.
- Trial name
- NMES (NCT00738010)
- Testing
- Kneehab, Poli-Stim, Control
- Where
- Germany
- Volunteers
- 131 people
- Sponsor
- Bio-Medical Research, Ltd.
Cancer, Lung, Cancer Liver
PixelShine vs. Iterative Reconstruction (IR) Processing of CT Images
This study will compare the quality of CT images acquired with very low-dose radiation and processed with commercially available software vs. PixelShine processed images.
- Conditions
- Cancer, Lung, Cancer Liver, X-rays; Effects
- Trial name
- NCT03033615
- Testing
- PixelShine, Conventional processing
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- AlgoMedica, Inc.
Rotator Cuff Tear
Arthroscopic Rotator Cuff Tear Repair: Single Versus Double Layer Fixation
Retear rates after arthroscopic rotator cuff repairs remain unsatisfactorily high. Recently, attention has been paid to restore the rotator cuff's native anatomy by reconstructing the superior joint capsule.
- Trial name
- NCT03362320
- Testing
- double layer fixation, single layer fixation
- Where
- Austria
- Volunteers
- 70 people
- Sponsor
- Austrian Research Group for Regenerative and Orthopedic Medicine
Breast Cancer Lymphedema
ILR to Prevent BRCL_MCC 23608
The goal of this clinical trial is to evaluate the effectiveness of Immediate Lymphatic Reconstruction (ILR) in preventing breast cancer-related lymphedema (BCRL) in high-risk patients.
- Trial name
- NCT07127003
- Testing
- Immediate Lymphatic Reconstruction
- Where
- 3 sites in United States
- Volunteers
- 98 people
- Sponsor
- University of South Florida
Breast Neoplasms
Does Autologous Fat Transplantation Improve Results and Reduce Complications in Breast Reconstruction With Implants?
The purpose of this study is to determine if autologous fat transplantation as a pre-treatment gives better results in breast reconstruction with implants after mastectomy and radiotherapy.
- Trial name
- NCT02637635
- Testing
- Autologous fat transplantation, Expander prosthesis
- Where
- Sweden
- Volunteers
- 45 people
- Sponsor
- Karolinska Institutet
Breast Cancer
Local and Regional Radiotherapy for Nipple Sparing Mastectomy With Implant
The prospective observational study of radiation therapy is conducted on the nipple-areola complex(close resection margin at primary tumor site) or regional lymph nodes(including axilla and supraclavicular lymph node) with a high…
- Trial name
- NCT05213962
- Where
- South Korea
- Volunteers
- 128 people
- Sponsor
- National Cancer Center, Korea
Ureteral Stenosis
An Investigation Into the Application of Preputial Grafts for the Reconstruction of Complex Ureteral Strictures
Complex ureteral stricture refers to a ureteral lumen stenosis lesion that cannot be directly treated with the traditional end-to-end anastomosis.
- Trial name
- PGU20240101 (NCT07408050)
- Testing
- Preputial graft ureteroplasty
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Ruibao chen
Breast Cancer, Breast Cancer Female
Microbiome and Association With Implant Infections
The most common tissue expander-related infections are from Staphylococcus and Pseudomonas species. In addition, from breast tissue microbiome studies, Staphylococcus and Pseudomonas show variable abundance across samples.
- Conditions
- Breast Cancer, Breast Cancer Female, Genetic Predisposition to Disease
- Trial name
- NCT05020574
- Testing
- Cephalexin
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of California, San Francisco
Prostate Cancer, Multiparametric MRI
Deep Learning Super Resolution Reconstruction for Fast and Motion Robust T2-weighted Prostate MRI
The aim of this study was therefore to investigate a new unrolled DL super resolution reconstruction of an initially low-resolution Cartesian T2 turbo spin echo sequence (T2 TSE) and compare it qualitatively and quantitatively to…
- Trial name
- NCT05820113
- Testing
- Deep learning based reconstruction of T2-TSE sequence
- Where
- Germany
- Volunteers
- 109 people
- Sponsor
- University Hospital, Bonn
Anterior Cruciate Ligament Injury, Knee Joint
ACL Prehabilitation and Functional Outcomes
Anterior cruciate ligament (ACL) rupture is a common knee injury that frequently requires surgical reconstruction and extensive postoperative rehabilitation.
- Trial name
- ACL Prehab fun (NCT07627724)
- Testing
- Preoperative Prehabilitation Program, Standard Preoperative Care
- Where
- Egypt
- Volunteers
- 76 people
- Sponsor
- Beni-Suef University
Breast Cancer, Breast Neoplasms, Breast Reconstruction
Evaluation of Wellbeing and Patient Reported Outcomes After Open vs Robotic Mastectomy With DIEP Reconstruction
Nipple-sparing mastectomy (NSM) preserves the nipple-areolar complex (NAC) and is associated with improved cosmetic outcomes, body image, and patient satisfaction compared with more ablative techniques.
- Conditions
- Breast Cancer, Breast Neoplasms, Breast Reconstruction, DIEP Flap Breast Reconstruction, Robotic Surgery
- Trial name
- REBORN (NCT07230535)
- Testing
- Robotic Assisted Nipple Sparing Mastectomy, Standarding Open Nipple Sparing Mastectomy
- Where
- Ireland
- Volunteers
- 250 people
- Sponsor
- Beaumont Hospital
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