Clinical trials: Imaging
Eczema, Psoriasis
Non-invasive Photoacoustic Imaging of Skin Inflammatory Disorders With Machine Learning-assisted Scoring
Inflammatory skin disorders are usually assessed by disease scoring system such as Scoring AD (SCORAD)/Eczema Area and Severity Index (EASI) and Psoriasis Area and Severity Index (PASI) for atopic eczema and psoriasis…
- Trial name
- NCT04809571
- Testing
- Photoacoustic imaging and Confocal Raman spectroscopy measurement
- Where
- Singapore
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- Institute of Bioengineering and Bioimaging (IBB)
Mild Cognitive Impairment, Dementia
Implications for Management of PET Amyloid Classification Technology
The main purpose of this study is to explore the impact of an amyloid positron emission tomography and computed tomography (PET/CT) scan on physician diagnosis and management, including drug management and care practices, for…
- Conditions
- Mild Cognitive Impairment, Dementia, Alzheimer's Disease
- Trial name
- IMPACT (NCT02778971)
- Testing
- [18F]Flutemetamol
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of Utah
Vascular Access Complication
Dual-plane Ultrasound Imaging During Vascular Access Procedures
Researchers are evaluating the clinical efficiency of utilization of a dual-plane simultaneous view ultrasound probe (Butterfly iQ+; Butterfly Network, Inc.) during arterial catheter placement in the operating room
- Trial name
- NCT05093699
- Testing
- Butterfly iQ+ ultrasound probe, Ultrasound probe
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Kawasaki Disease
The Value of Cardiovascular Imaging in Kawasaki Disease
The goal of this observational study is to assess the cardiovascular injury of Kawasaki disease with multi-modal imaging combined with clinical data.
- Trial name
- NCT06641817
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- West China Second University Hospital
Glioma, Breast Cancer
68Ga-NOTA-NFB: Radiation Dosimetry in Healthy Volunteers and Applications in Glioma Patients or Breast Cancer Patients
The purpose of this study is to assess the safety, biodistribution, dosimetric properties of the positron emission tomography (PET) radiopharmaceutical agent 68Ga-NOTA-NFB.
- Trial name
- GNNGB (NCT02327442)
- Testing
- 68Ga-NOTA-NFB
- Where
- China
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Ultrasound Imaging, Supraglottic Airway Device
Ultrasound Imaging to Validate I-gel Placement in pediatrıc Patients
For nearly half a century, supraglottic airway devices (SGA) have been used in pediatric patients, which are more practical than face masks, facilitate oxygenation and ventilation without the need for endotracheal intubation, and…
- Conditions
- Ultrasound Imaging, Supraglottic Airway Device, Fiberoptic Bronchoscopy
- Trial name
- NCT04652466
- Testing
- farukcicekci2
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Multiple Myeloma
64Cu-LLP2A for Imaging Multiple Myeloma
The investigators are performing a trial with goals to demonstrate the feasibility of imaging multiple myeloma (MM) patients with 64Cu-LLP2A-positron emission tomography (PET)/magnetic resonance (MR).
- Trial name
- NCT03804424
- Testing
- 64Cu-LLP2A, PET/MR, Blood samples for serum stability
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Major Depressive Disorder, Menopausal Staging and Vasomotor Symptoms (for Females)
Desvenlafaxine Succinate (DVS) for Major Depressive Disorder (MDD) in Midlife Men and Women
The main objective of this study is to characterize a range of brain activation symptoms associated with depression and response to treatment in midlife men and women with MDD, using MRI and functional MRI.
- Trial name
- DVS (NCT00888862)
- Testing
- Desvenlafaxine Succinate
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Hamilton Health Sciences Corporation
Frontotemporal Lobar Degeneration, Alzheimer Disease
PET Imaging Tau Accumulation in FTLD and Atypical Alzheimer's Using [18F]-PI-2620
The investigators will compare [18F]-PI-2620 tau PET scans from patients with frontotemporal lobar degeneration (FTLD), patients with non-amnestic presentations of Alzheimer's disease (naAD), and demographically matched…
- Conditions
- Frontotemporal Lobar Degeneration, Alzheimer Disease, Cognitively Normal
- Trial name
- NCT05456503
- Testing
- [18F]-PI-2620
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Fibromyalgia, Pain, Chronic
Psychobiological Mechanisms Underlying Chronic Pain
Pain is a powerful motivator of behavior and it is more than the perception of nociceptive input. It is a complex experience that comprises different components: sensory discriminative, emotional-motivational and cognitive…
- Conditions
- Fibromyalgia, Pain, Chronic, Chronic Pain, Widespread
- Trial name
- NCT04674670
- Testing
- Bromocriptine Mesylate Capsules, Amisulpride 400 MG
- Where
- Switzerland
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- susanne becker
Sickle Cell Disease
Spectralis HRA+OCT Imaging of the Retina With Autofluorescence in Sickle Cell Disease
To determine the retinal and choroidal thickness in patients with sickle cell disease compared to age, race matched population without sickle cell disease to allow a better understanding of the clinical manifestations of sickle…
- Trial name
- NCT01123369
- Where
- 2 sites in United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Liver Cirrhoses, Hepatic Encephalopathy
Role of MRI in Detection of Minimal Hepatic Encephalopathy
Introduction Liver cirrhosis (LC) is irreversible fibrosis of the liver (1) and it remains a public health problem. One of the complications of the cirrhosis is hepatic encephalopathy (HE) which is defined as brain dysfunction…
- Trial name
- NCT04131205
- Testing
- Magnetic Resonance Imaging
- Where
- Slovenia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Alzheimer's Disease, Healthy Volunteer
Evaluation of [11C]RO6924963, [11C]RO6931643, and [18F]RO6958948 as Tracers for Positron Emission Tomography (PET) Imaging of Tau in Healthy and Alzheimer's Disease (AD) Participants
This study is designed to obtain basic information on three PET imaging tracers developed to detect tau pathology in the brain. In this study, healthy control participants and participants with AD will be studied.
- Trial name
- NCT02187627
- Testing
- [11C]RO6924963, [11C]RO6931643, [18F]RO6958948
- Where
- 2 sites in United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Hoffmann-La Roche
Metastatic Breast Cancer, Benign Breast Disease
China CellSearch Study
The study is designed to confirm the current indication (below) of the CellSearch® Circulating Tumor Cell Kit in metastatic breast cancer (MBC) patients for use of the kit in China.
- Trial name
- NCT01116869
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Medical, China
Parkinson Disease
Comparison of Different Rehabilitation Protocols in Parkinson's Disease With Postural Instability and Gait Disorders
The aim of the study is to compare the effects of 2 different dosages and modalities of motor-cognitive rehabilitation in Parkinson's disease with postural instability and gait disorders (PD-PIGD) on clinical features…
- Trial name
- NCT05799690
- Testing
- Gait and balance training with dual-task + action observation and motor imagery (six weeks), Gait and balance training with dual-task (six weeks), Gait and balance training with dual-task + action observation and motor imagery (twelve weeks: 6 + 6)
- Where
- 2 sites in Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Prof. Massimo Filippi
Brain Health
Brain Imaging Study
The study is designed to evaluate the effects of the proprietary nutritional supplement on cognition, mood, and brain imaging parameters following a relatively short period of treatment.
- Trial name
- NCT02439983
- Testing
- Proprietary Nutritional Supplement
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Pharmanex
Feeding Behavior, Brain
Food Intake and the Adolescent Brain
The brain plays an integral role in how and what people eat. However, the brain's contribution to overeating is not well understood during sensitive developmental periods such as adolescence, when excessive weight gain and…
- Conditions
- Feeding Behavior, Brain, Adolescent
- Trial name
- ADOB (NCT04208256)
- Testing
- Energy Stimulus
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Healthy, Chronic Kidney Diseases
A Study of Renal Microvessel Imaging for Chronic Kidney Disease
The purpose of this research is to study the efficacy of ultrasound microvessel imaging for evaluation of Chronic Kidney Disease.
- Trial name
- NCT05764642
- Testing
- Definity, Super-resolution ultrasound imaging
- Where
- 2 sites in United States
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Breast Cancer, Lymphedema
PRELUDE Study of Lymphatic Surgery to Treat Breast Cancer Related Lymphoedema
Lymphoedema is a chronic debilitating disease that can have severe adverse effects on day-to-day life causing great physical and visual discomfort.
- Trial name
- PRELUDE (NCT04579029)
- Testing
- Lymphaticovenous anastomosis surgery combined with near infrared spectroscopy imaging
- Where
- 2 sites in United Kingdom
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Royal Marsden NHS Foundation Trust
Esophagus Cancer, Esophageal Cancer
Utility and Usability of ActivSight™ Laser Speckle Imaging in Visualization of Tissue Perfusion and Blood Flow During Esophageal Surgery in Humans
ActivSight™ combines an innovative form factor and proprietary software to deliver precise, objective, real-time visualization of blood flow and tissue perfusion intraoperatively for laparoscope-based surgery.
- Conditions
- Esophagus Cancer, Esophageal Cancer, Esophageal Neoplasms, Esophageal Diseases
- Trial name
- NCT05591053
- Testing
- ActivSight
- Where
- 2 sites in United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Activ Surgical