Clinical trials: Imaging
Magnetic Resonance Imaging, Tetralogy of Fallot
4D Velocity Mapping of the Heart in rTOF Patients
MRI with 4D flow permits to assess the hemodynamic parameters in a parent vessel and its branches inside the same sequence.
- Trial name
- CARDIOFLUX (NCT02980614)
- Testing
- 4D flow imaging
- Where
- France
- Volunteers
- 21 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Respiratory Complication, Fetal Lung Imaging
Characterization of Fetal Lung With Quantitative Ultrasound
The purpose of the study is to show if it's possible to use a special kind of ultrasound called backscatter quantitative ultrasound (bQUS) to check on a baby's lungs when the mother is 36 weeks pregnant.
- Trial name
- NCT06722365
- Testing
- Backscatter Quantitative Ultrasound
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Breast Cancer, Sentinel Lymph Node Biopsy (SLNB)
Implementation of Indocyanine Green to Identify Sentinel Lymph Nodes During Surgery for Breast Cancer
The goal of this clinical trial is to learn how to successfully introduce a new method for finding the sentinel lymph node during breast cancer surgery into routine hospital care.
- Conditions
- Breast Cancer, Sentinel Lymph Node Biopsy (SLNB), Sentinel Lymph Node Detection, Sentinel Lymph Node
- Trial name
- INFINITE (NCT07146295)
- Testing
- Technetium (99mTc), Indocyanine Green, Sentinel lymph node biopsy
- Where
- 7 sites in Netherlands
- Volunteers
- 1,760 people
- Sponsor
- Isabelle Henskens
Magnetic Resonance Imaging (MRI)
New Simulation Care Pathway for Paediatric MRI Preparation
Magnetic resonance imaging (MRI) is a common imaging procedure that is safe and non-invasive, as it relies on the use of different magnetic fields. It is the gold standard examination for a wide range of pathologies.
- Trial name
- NCT07344753
- Testing
- Realization of the immersive experience, Completion of study questionnaires, Questioning the child's emotional feelings
- Where
- France
- Volunteers
- 114 people
- Sponsor
- Nantes University Hospital
Cardiovascular Imaging, Echocardiography
Assessment of Cardiac and Carotid Ultrasound Measurements in a Cohort of Healthy Children in Italy
This observational ambispective cohort study aims to establish reference values for cardiac structure and function, coronary artery dimensions, and carotid intima-media thickness (cIMT) in a healthy pediatric population living in…
- Conditions
- Cardiovascular Imaging, Echocardiography, Carotid Intima-Media Thickness
- Trial name
- NORMECO (NCT07666451)
- Where
- Italy
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Neoplasms, Whole Body Imaging
Impact of Free Mobility on FDG Uptake in PET Scans
Positron Emission Tomography (PET) is a rather long examination (around 2 hours), involving an injection of 18F-Fluorodeoxyglucose (FDG), which requires the patient to rest for 1 hour between the injection and the start of…
- Trial name
- MOBITEP (NCT06799819)
- Testing
- Mobility group
- Where
- France
- Volunteers
- 284 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Visualization of Ureters in Gynecological Surgery, Deep Infiltrative Endometriosis
ICG for Visualization of the Ureters in DIE
Endometriosis is a common condition with an incidence of approximately 10% of all women in the fertile phase. Deep infiltrating endometriosis (DIE) has been shown to be associated with high morbidity.
- Conditions
- Visualization of Ureters in Gynecological Surgery, Deep Infiltrative Endometriosis, ICG (Indocyanine Green), Near Infrared Imaging
- Trial name
- Lavic (NCT05206279)
- Testing
- Ureteral injection of Indocyanine Green Powder (diluted)
- Where
- Switzerland
- Volunteers
- 51 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Magnetic Resonance Imaging
A Neonatal Bimodal MR-CT Head Template
This is a retrospective study based on the images contained in the database of the University Hospital of Amiens. There is no further examination. Electroencephalography (EEG) and Near-Infrared Spectroscopy (NIRS).
- Trial name
- Biomodal (NCT03674034)
- Testing
- CTscan and MRI images
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Covid19, Bronchoscopy
Narrow Band Imaging Bronchoscopy During SARS-CoV2 Infection
Vascular modifications have been described during SARS-CoV2 infection, especially a dilatation of the bronchial arteries. Within the airway wall, small branches of the bronchial arteries cross the muscle layer to develop a…
- Conditions
- Covid19, Bronchoscopy, Narrow-band Imaging
- Trial name
- SARS-CoV2-NBI (NCT04884061)
- Testing
- NBI images and/or videos
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Traumatic Brain Injury, Magnetic Resonance Imaging (MRI)
PASTRAMI : Patient-specific Statistics for Microstructure-augmented Connectomics
Traumatic brain injury (TBI) represent a major public health issue, accounting for approximately 1.5 million hospital admissions annually across the European Union and 160,000 cases in France.
- Trial name
- PASTRAMI (NCT07527949)
- Testing
- Measures of brain microstructure
- Where
- 2 sites in France
- Volunteers
- 100 people
- Sponsor
- Rennes University Hospital
Autofluorescence Imaging, Neuroimaging
Measurement of Retinal Auto Fluorescence With a Fluorescence Lifetime Imaging Ophthalmoscope
Fluorescent lifetime microscopy has emerged as a useful tool to study fluorescent lifetimes in vitro. Fluorescence lifetime represents the average amount of time a fluorophore remains in the excited state following excitation and…
- Trial name
- FLIO-Group (NCT01981148)
- Testing
- Fluorescence lifetime ophthalmoscope
- Where
- Switzerland
- Volunteers
- 892 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Metastatic Breast Cancer, Metastatic Prostate Cancer
First-in-human Diagnostic Imaging Profile of the Theranostic Pair [68Ga]Ga-DOTA-STR-17126 and Low Dose [177Lu] Lu-DOTA-STR-17126 in Patients With Advanced or Metastatic Cancer
This is an open-label, first-in-human, exploratory Phase 0 study evaluating the safety and diagnostic imaging performance of the DOTA-STR-17126 theranostic pair in patients with advanced or metastatic breast or prostate cancer.
- Conditions
- Metastatic Breast Cancer, Metastatic Prostate Cancer, GRPR-Targeted Molecular Imaging, Theranostic Radiopharmaceuticals
- Trial name
- DOTA-STR-17126 (NCT07608848)
- Testing
- [177Lu]Lu-DOTA-STR-17126, [68Ga]Ga-DOTA-STR-17126
- Where
- Australia
- Volunteers
- 20 people
- Sponsor
- Integrated Haematology and Oncology Network
Adipocytes, Autografts
3D Facial Scanning for Evaluating Autologous Fat Grafting in Craniofacial Deformities
Treatment of craniofacial deformities is a significant topic in oral and maxillofacial surgery, and autologous fat grafting has become one of the main methods for treating facial concave deformities.
- Conditions
- Adipocytes, Autografts, Imaging, Three-Dimensional / Methods
- Trial name
- NCT06306326
- Testing
- 3dMD technology
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Peking University
Breast Neoplasms, Artificial Intelligence (AI)
Non-Contrast Breast MRI Diagnosis and Risk Stratification Using DWI-Generated Synthetic Contrast Enhancement
This study is conducted under the ethics-approved project titled "Artificial Intelligence Solution for Simplifying the Diagnostic Workflow of Breast MRI''.The goal of this observational study is to develop an integrated breast…
- Conditions
- Breast Neoplasms, Artificial Intelligence (AI), Magnetic Resonance Imaging (MRI), Diffusion Magnetic Resonance Imaging
- Trial name
- NCT07598084
- Testing
- Non-contrast breast MRI diagnostic model
- Volunteers
- 12,000 people, healthy volunteers welcome
- Sponsor
- Peking University People's Hospital
Glioblastoma, Brain Tumors
Assessment of Early Post-operative Nuclear Imaging in Neurosurgery: a Safety and Feasibility Study in Patients Operated for Glioblastoma
This clinical trial aims to evaluate the feasibility and safety of early post-operative brain PET-MRI imaging in adult patients who have undergone surgery for suspected glioblastoma.
- Conditions
- Glioblastoma, Brain Tumors, Brain Imaging
- Trial name
- EARLYBRAINPET (NCT07274397)
- Testing
- Early post-operative brain PET-MRI with 18F-DOPA and Gadolinium
- Where
- France
- Volunteers
- 15 people
- Sponsor
- Beta Emitting Accurate Monitored Systems
Cardiovascular Disease Acute, Emergency Department Patient
Cardiac point-of Care Ultrasound Training Pathway for Emergency Department Advanced Practice Providers
The aim of this study is to assess emergency medicine physician and advanced practice provider (APP) knowledge and technical skill in performance of a point-of-care ultrasound simulation and just-in-time training pathway to…
- Conditions
- Cardiovascular Disease Acute, Emergency Department Patient, Heart Failure Acute, Pulmonary Embolism (Diagnosis)
- Trial name
- NCT07159269
- Testing
- Cardiac point-of-care ultrasound (POCUS) training and clinical pathway
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Duke University
Magnetic Resonance Imaging, Brain Neoplasms, Childhood
Fast Brain MRI in Children With Suspected Brain Tumor
This study aims to assess the diagnostic performance of a new fast MRI sequence named Neuromix compared to routine clinical MRI for brain tumor in pediatric patients
- Conditions
- Magnetic Resonance Imaging, Brain Neoplasms, Childhood, Brain Neoplasms, Brain Tumor
- Trial name
- Fast MRI (NCT05776602)
- Testing
- Fast MRI (Neuromix)
- Where
- Sweden
- Volunteers
- 32 people
- Sponsor
- Karolinska University Hospital
Repetitive Transcranial Magnetic Stimulation (rTMS), Functional Magnetic Resonance Imaging
Repeated Transcranial Magnetic Stimulation Relieves Maternal Care Impairment
Objective: To evaluate the overall efficacy of repetitive transcranial magnetic stimulation (rTMS) in the treatment of maternal care impairment (MCI) and to explore the central mechanism of rTMS for MCI.
- Conditions
- Repetitive Transcranial Magnetic Stimulation (rTMS), Functional Magnetic Resonance Imaging, Maternal Care Patterns
- Trial name
- NCT06743724
- Testing
- rTMS group
- Where
- 2 sites in China
- Volunteers
- 45 people
- Sponsor
- The First Affiliated Hospital of Soochow University
Depression - Major Depressive Disorder, Bipolar Disorder (BD)
Flumazenil for Benzodiazepine Reversal in Electroconvulsive Therapy
The goal of this study is to investigate whether administering flumazenil to reverse the effects of benzodiazepines and/or zopiclone during electroconvulsive therapy (ECT) can help reduce cognitive side effects without…
- Conditions
- Depression - Major Depressive Disorder, Bipolar Disorder (BD), Functional Magnetic Resonance Imaging (fMRI), Cognition
- Trial name
- FLEET (NCT07619092)
- Testing
- Flumazenil, Electroconvulsive therapy (ECT)
- Where
- Denmark
- Volunteers
- 145 people
- Sponsor
- Anders Jørgensen
Interstitial Lung Disease, Interstitial Lung Diseases
Ultrasound and Respiratory Physiological Signals in Lung Diseases
The use of lung ultrasound is instrumental in the evaluation of many chest pathologies and its ability to detect pleuro-pulmonary pathology is widely accepted.
- Conditions
- Interstitial Lung Disease, Interstitial Lung Diseases, Interstitial Pneumonia, Chronic Obstructive Pulmonary Disease
- Trial name
- SAURON (NCT06068647)
- Testing
- Lung ultrasound, computed tomographic scan and patch-based cardio-respiratory evaluations
- Where
- Italy
- Volunteers
- 25 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS