Clinical trials: Imaging Guided
Breast Neoplasm, Lymphedema
Effectiveness of Fluoroscopy-guided MLD for Treatment of BCRL
The main scientific objective of this multicentric double-blinded randomised controlled trial entails examining the effectiveness of fluoroscopy-guided MLD versus traditional MLD versus placebo MLD, applied as part of the…
- Trial name
- EFforT-BCRL (NCT02609724)
- Testing
- Information, Skin care, Compression therapy
- Where
- 3 sites in Belgium
- Volunteers
- 194 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Breast Cancer, Sentinel Lymph Node Biopsy (SLNB)
Finding Sentinel Lymph Nodes During Mastectomy Using Indocyanine Green (INIGMA Study)
This pilot study evaluates the diagnostic value of indocyanine green (ICG) fluorescence for sentinel lymph node biopsy (SLNB) performed through the mastectomy incision in breast cancer patients.
- Conditions
- Breast Cancer, Sentinel Lymph Node Biopsy (SLNB), Sentinel Lymph Node Detection, Sentinel Lymph Node
- Trial name
- INIGMA (NCT07362485)
- Testing
- Indocyanine green (ICG)-fluorescence guided sentinel lymph node biopsy
- Where
- 2 sites in Netherlands
- Volunteers
- 90 people
- Sponsor
- Isabelle Henskens
Depression, Major Depressive Disorder
Individualized (fMRI-guided) TMS Treatment for Depression
The purpose of this study is to investigate the responses of the brain region known as the subgenual anterior cingulate cortex (sgACC) during transcranial magnetic stimulation (TMS) in individuals with depression.
- Conditions
- Depression, Major Depressive Disorder, Persistent Depressive Disorder
- Trial name
- NCT06266390
- Testing
- Transcranial Magnetic Stimulation (TMS)
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- University of Pennsylvania
Breast Cancer
Efficacy of IORT With CT-Guided HDR Brachytherapy for Treatment of Breast Cancer
The purpose of this study is to evaluate an investigational way to provide radiation therapy to treat early-stage breast cancer at the time of surgery.
- Trial name
- NCT02400658
- Testing
- IORT with CT-Guided HDR Brachytherapy
- Where
- 3 sites in United States
- Volunteers
- 358 people
- Sponsor
- Shayna Showalter, MD
Prostate Cancer
Deformable Registration of Multi-parametric MRI to Intra-operative Transrectal Ultrasound for Prostate Brachytherapy
Objective: To focus the high dose radiation to the gross tumor in the prostate while maintaining adequate dose for control of microscopic disease elsewhere in the prostate.
- Trial name
- NCT02790216
- Testing
- Brachytherapy
- Where
- Israel
- Volunteers
- 24 people
- Sponsor
- Sheba Medical Center
Ultrasound Imaging, Caudal Block
Out Of-plane Technique Against In-plane for Caudal Block
Caudal block is an easy and effective type of central neuraxial block that is widely used in subumbilical surgeries to provide intraoperative and postoperative analgesia in the pediatric population.
- Conditions
- Ultrasound Imaging, Caudal Block, Hypospadias
- Trial name
- NCT04671992
- Testing
- Out of-Plane Technique and In-Plane on
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Valvular Heart Disease Patients, Aortic Stenosis
Importance of Point-of-Care Ultrasound for Early Detection of Valvular and Cardiac Diseases (IMPROVE)
Heart valve disease and weakened heart muscle (left ventricular systolic dysfunction) are common in older adults and often go undetected until serious complications such as heart failure develop.
- Conditions
- Valvular Heart Disease Patients, Aortic Stenosis, Mitral Regurgitation, Left Ventricular Diastolic Dysfunction
- Trial name
- IMPROVE (NCT07756398)
- Testing
- Kosmos Torso-One AI-guided Point-of-Care Ultrasound (EchoNous, Inc.)
- Where
- 2 sites in United States
- Volunteers
- 1,088 people
- Sponsor
- University of Texas Southwestern Medical Center
Ischemic Heart Disease
Early Revascularization in Stable Ischemic Heart Disease Using P.E.T. Imaging
To compare the impact of revascularization and Optimal Medical Treatment (OMT) on the extent of severely reduced coronary flow capacity in stable ischemic heart disease.
- Trial name
- PETREVASC (NCT05018247)
- Testing
- Revascularization by Coronary Artery Bypass Graft or Percutaneous Coronary Intervention
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- The University of Texas Health Science Center, Houston
Colorectal Surgery, Colorectal Resection
AUGUR-AI - Indocyanine Green Fluorescence Angiography Representer
Surgery can effectively treat colorectal cancer, but it is a complex procedure with risks and complications. Surgeons often rely on cameras to visually guide their instruments during operations, especially in minimally invasive…
- Conditions
- Colorectal Surgery, Colorectal Resection, Anastomosis, Surgical, Fluorescence Guided Surgery
- Trial name
- AUGUR-AI (NCT06708819)
- Where
- Ireland
- Volunteers
- 300 people
- Sponsor
- Mater Misericordiae University Hospital
Pancreas Adenocarcinoma (MSI-H), Pancreatic Neuroendocrine Tumors (pNET)
Superb Microvascular Imaging (SMI) and Two-Dimensional Endoscopic Ultrasound Guided Shear Wave Elastography (2D-SWE-EUS) in Differential Diagnosis of Pancreatic Adenocarcinoma (PA) From Other Pancreatic Solid Lesions (PSLs) and Pancreatic neuroendocrinE Tumors (pNETs) Malignancy
Pancreatic adenocarcinoma (PA) is the most common tumor of the pancreas. Given its poor prognosis and the major therapeutic consequences, the discrimination between PA and other pancreatic solid lesions is mandatory.
- Trial name
- SMILE (NCT07274657)
- Testing
- SMI and 2D-SWE modes
- Where
- France
- Volunteers
- 150 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Retinal Detachment, Epiretinal Membrane
PIONEER: Intraoperative and Perioperative OCT Study
OCT provides high-resolution information regarding the anatomic structure of the tissues of the eye in a 2-dimensional and 3-dimensional view. Much of this information is not able to be recognized by a clinician.
- Conditions
- Retinal Detachment, Epiretinal Membrane, Macular Hole, Fuchs Endothelial Dystrophy
- Trial name
- PIONEER (NCT02423161)
- Where
- United States
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Prostate Cancer
Imaging for Significant Prostate Cancer Risk Evaluation
The incidence of prostate cancer is rising however the number of deaths from prostate cancer is stable. Meaning the investigators are diagnosing many men with prostate cancer that will not impact on their life.
- Trial name
- PICTURE (NCT01492270)
- Testing
- Prostate HistoScanning, Multi-parametric MRI, Transperineal prostate mapping biopsy
- Where
- United Kingdom
- Volunteers
- 126 people
- Sponsor
- University College London Hospitals
Imaging Guided, Percutaneous Cementoplasty
Imaging Guided Cementoplasty for Pelvic Bone Metastasis
This study aimed to summarize the immediate operative and short-term efficacy and safety outcomes of percutaneous cementoplasty for pelvic metastases
- Conditions
- Imaging Guided, Percutaneous Cementoplasty, Pelvic Bone Metstasis
- Trial name
- NCT06231628
- Testing
- Percutaneous cementoplasty
- Volunteers
- 20 people
- Sponsor
- Assiut University
Muscle-invasive Bladder Cancer, Artificial Intelligence
Multi-parametric MRI in Patients of Bladder Cancer
Accurate preoperative detection of muscle-invasive bladder cancer remains a clinical challenge. The investigators aimed to develop and validate a knowledge-guided causal diagnostic network for the detection of muscle-invasive…
- Trial name
- NCT06362330
- Testing
- magnetic resonance imaging
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Cardiac Disease, Heart Failure
Interactive Guided Ultrasound Examinations Done by Non-experts of Ultrasound Imaging
This prospective study is a pilot study for evaluating a guidance system that aims to facilitate high-quality echocardiographic acquisitions.
- Conditions
- Cardiac Disease, Heart Failure, Cardiac Ischemia
- Trial name
- EPISODE (NCT03642730)
- Testing
- TransThoracic Echocardiography imaging
- Where
- France
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Philips Healthcare
PCI, In-stent Restenosis
Intravascular Imaging-Guided Versus Angiography- Guided PCI in Patients With DES-ISR
This study aimed to compare the clinical and angiographic outcomes of patients with DES-ISR who underwent repeat PCI with intravascular imaging or angiographic guidance.
- Conditions
- PCI, In-stent Restenosis, Intravascular Imaging Device
- Trial name
- NCT07297641
- Testing
- percutaneous coronary intervention
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Leiomyoma, GIST
Detective Flow Imaging Endoscopic Ultrasonography in Subepithelial Lesions
Gastrointestinal stromal tumors (GIST) are the most common malignant subepithelial lesions (SELs) found in the gastrointestinal tract.
- Trial name
- NCT05474794
- Testing
- DFI-EUS, CE-EUS
- Where
- Ecuador
- Volunteers
- 30 people
- Sponsor
- Instituto Ecuatoriano de Enfermedades Digestivas
Prostate Neoplams, Magnetic Resonance Imaging, Laser Ablation
MRI-guided Focal Laser Ablation Prostate Cancer
Prostate cancer is the most frequent malignancy in the male population of developed countries and has a substantial socio-economic impact.
- Trial name
- NCT05370482
- Testing
- Focal laser ablation
- Where
- Netherlands
- Volunteers
- 10 people
- Sponsor
- Radboud University Medical Center
Neuropathic Pain, Magnetic Resonance Imaging
Multimodal MRI for MRgFUS Central Lateral Thalamotomy in Neuropathic Pain
To explore the pathogenesis underlying neuropathic pain as well as the mechanisms of pain relief after Magnetic resonance-guided focused ultrasound (MRgFUS) Central Lateral Thalamotomy through multi-model MRI study, and to…
- Trial name
- NCT05122403
- Testing
- MRgFUS central lateral thalamotomy
- Where
- China
- Volunteers
- 12 people
- Sponsor
- Chinese PLA General Hospital
Colorectal Cancer, Liver Metastases
A Study of Single Fraction Stereotactic Body Radiation Therapy (SBRT) Guided by Magnetic Resonance Imaging (MRI) in People With Liver Metastasis From Colorectal Cancer
The researchers are doing this study to see if one session of high-dose contrast-enhanced MRI-guided SBRT (stereotactic body radiation therapy) is effective for colorectal cancer that has spread to the liver.
- Trial name
- NCT06130280
- Testing
- MR Guided Single Fraction Stereotactic Body Radiation Therapy (SBRT)
- Where
- 7 sites in United States
- Volunteers
- 32 people
- Sponsor
- Memorial Sloan Kettering Cancer Center