Clinical trials: Immediate Effect
Asthma, Exercise-Induced Bronchoconstriction
Effect of a Component of Fish Oil on Exercise-Induced Bronchoconstriction and Airway Inflammation in Asthma
The primary aim of this study will be to evaluate the effects of Lyprinol® supplementation on airway inflammation and the bronchoconstrictor response to dry air hyperpnea in individuals with asthma.
- Trial name
- NCT01504646
- Testing
- Lyprinol
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Indiana University
Asthma
A Study of the Bronchodilator Effect of Formoterol Fumarate Used in Combination With Mometasone Furoate Metered Dose Inhaler in Children With Persistent Asthma (P06476 AM2)
A study to compare the bronchodilatory effect of a single dose of Mometasone Furoate/Formoterol Fumarate (MF/F) pressurized metered dose inhaler (MDI) delivered with and without an AeroChamber Plus® with Flow-Vu® Anti-Static…
- Trial name
- NCT01258803
- Testing
- Formoterol Fumarate DPI, Mometasone Furoate/Formoterol Fumarate MDI (ex-actuator) without spacer, Mometasone Furoate/Formoterol Fumarate MDI (ex-actuator) with spacer
- Volunteers
- 92 people
- Sponsor
- Organon and Co
Atopic Dermatitis
Study to Determine the Effect of an Anti-IgE Agent on Inflammatory Cells in the Skin of Atopic Dermatitis Patients
Elevated levels of immunoglobuline E in blood are said to promote the occurence of atopic dermatitis; in fact, many patients with atopic dermatitis have high IgE levels.
- Trial name
- NCT00822783
- Testing
- Omalizumab
- Where
- Austria
- Sponsor
- Medical University of Vienna
Asthma
Safety and Efficacy of QAW039 in Sputum Eosinophilia and Persistent Asthma
This study will assess the safety and efficacy of QAW039 when added to current therapy in patients that have sputum eosinophilia and persistent asthma.
- Trial name
- NCT01545726
- Testing
- QAW039
- Where
- United Kingdom
- Volunteers
- 61 people
- Sponsor
- Novartis Pharmaceuticals
Asthma, Allergic Rhinitis
Effects of Lipoic Acid on Oxidative, Inflammatory and Functional Markers in Asthmatic Patients
The aim of the study is to use the antioxidant and antiinflammatory effects of lipoic acid to improve the quality of life of patients with asthma.
- Trial name
- NCT01221350
- Testing
- Lipoic acid
- Where
- 2 sites in Mexico
- Volunteers
- 55 people
- Sponsor
- Centro Universitario de Ciencias de la Salud, Mexico
Seasonal Allergic Rhinitis
Comparison of the Effects of Desloratadine and Placebo in the Relief of Nasal Symptom Scores in Subjects With Seasonal Allergic Rhinitis to Cypress Pollen (Study P02836)
The purpose of this study was to demonstrate the efficacy (% of change from baseline) of desloratadine to improve the nasal total symptom score of SAR to cypress pollen.
- Trial name
- NCT00867191
- Testing
- Desloratadine
- Volunteers
- 233 people
- Sponsor
- Organon and Co
Allergic Rhinitis, Asthma
Allergic Inflammation in Rhinitis Patients Following Nasal Allergen Challenge
Allergic rhinitis is a common condition caused by inflammation of nasal mucosa. The study was performed to gain information on this inflammation, including effect of intranasal corticosteroid treatment hereupon and potential…
- Trial name
- NCT01657097
- Testing
- INCS
- Where
- Denmark
- Volunteers
- 24 people
- Sponsor
- University of Aarhus
Hypersensitivity, Psychologic Factors in Physical Conditions Classified Elsewhere
Interaction Effect of Asthma and Aeroallergen Category on the Psychological Status in Allergic Rhinitis Patients
Allergic rhinitis (AR) and asthma are considered as "one airway, one disease". Although there is increasing evidence for an association between allergy and depression, it remains unknown if the relationship between AR and asthma…
- Conditions
- Hypersensitivity, Psychologic Factors in Physical Conditions Classified Elsewhere, Respiratory Tract Diseases, Allergic Rhinitis
- Trial name
- NCT01295255
- Volunteers
- 524 people
- Sponsor
- Beijing Tongren Hospital
Obesity
Analysing Differences in Glycaemic Control Immediately Post Obesity SurgEry (The ADIPOSE Study)
It is well established that bariatric (weightloss) surgery affords considerable improvement in glycaemic control (control of blood sugar), and in many cases may lead to a complete resolution of type 2 diabetes.
- Trial name
- ADIPOSE (NCT01515059)
- Where
- United Kingdom
- Volunteers
- 16 people
- Sponsor
- University of Leicester
Chronic Neck Pain
Electroacupuncture on Neck Muscle Stiffness in Chronic Neck Pain
This randomized, single-blind, placebo-controlled clinical trial aims to investigate the immediate physiological effects of a single session of electroacupuncture (EA) on neck muscle stiffness in individuals with chronic neck…
- Trial name
- NCT07741227
- Testing
- Electroacupuncture
- Where
- Hong Kong
- Volunteers
- 66 people
- Sponsor
- The Hong Kong Polytechnic University
Asthma
A Two-week Study Assessing the Onset of Effect Questionnaire (OEQ) Administered Daily Versus Weekly in Adult Subjects
The purpose of this study is to demonstrate whether subjects respond similarly to the Onset of Effect Questionnaire (OEQ) using a 1 week recall period versus a 1 day recall period.
- Trial name
- NCT00449527
- Testing
- Budesonide/formoterol pMDI, Budesonide HFA pMDI
- Where
- 44 sites in United States
- Volunteers
- 123 people
- Sponsor
- AstraZeneca
Asthma
Effect of Ciclesonide on Quality of Life in Patients With Moderate Persistent Asthma (21 to 65 y) (BY9010/AR-101)
The aim of the study is to compare the effect of ciclesonide on quality of life, pulmonary function and time to first exacerbation in patients with moderate persistent asthma.
- Trial name
- NCT00305461
- Testing
- Ciclesonide
- Where
- 12 sites in Argentina
- Volunteers
- 101 people
- Sponsor
- AstraZeneca
Asthma
Analysis of Exhaled Breath by Biosensors in Adults With Asthma
The aim of this study is to investigate the pattern of organic volatile compounds (VOCs) in the exhaled breath detected by biosensors in adults with persistent mild asthma.
- Trial name
- NCT00819676
- Testing
- analysis of exhaled breath by biosensors, measurement of exhaled nitric oxide
- Where
- Italy
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Catholic University of the Sacred Heart
Atopic Dermatitis
The Therapeutic Effects of Topical Cannabidiol (CBD) Products for Atopic Dermatitis
The goal of this observational study is to learn about the potential therapeutic effects of topical CBD products produced by Phoilex Ltd., specifically the Releaf Gel, in those diagnosed with atopic dermatitis.
- Trial name
- NCT06022874
- Testing
- Phoilex Releaf Gel
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Phoilex Ltd.
Healthy
Dynamic Electrostimulation on the Abdominal Muscles in Healthy Individuals
To determine the immediate effects on the abdominal musculature, assessed by ultrasound (RUSI), due to the application of electrostimulation using whole body electrostimulation together with physical exercise in healthy people…
- Trial name
- NCT05117203
- Testing
- WB-EMS (Whole body electrostimulation), EMS, WB-EMS off
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Universidad de León
Allergic Rhinitis
Alpha-Blockers in Allergic Rhinitis (MAN 01)
Allergic rhinitis (allergic inflammation of the nose) is a common medical condition which is known to seriously decrease quality of life, aggravate preexisting conditions particularly asthma, carry significant medical treatment…
- Trial name
- MAN01 (NCT01946035)
- Testing
- Doxazosin XL
- Where
- United Kingdom
- Volunteers
- 17 people
- Sponsor
- University of Dundee
Asthma, Chronic Obstructive Pulmonary Disease
Study of ARO-MUC5AC in Healthy Subjects and Patients With Muco-Obstructive Lung Disease
The purpose of this study is to evaluate the safety, tolerability, and pharmacokinetics (PK) of ARO-MUC5AC in normal healthy volunteers (NHVs), patients with moderate-to-severe asthma and patients with moderate-to-severe chronic…
- Trial name
- NCT05292950
- Testing
- ARO-MUC5AC
- Where
- 13 sites in Australia, New Zealand and 5 more
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Arrowhead Pharmaceuticals
Eosinophilic Esophagitis
A Study to Evaluate the Efficacy and Safety of CC-93538 in Adult and Adolescent Participants With Eosinophilic Esophagitis
Study CC-93538-EE-001 is a Phase 3, multicenter, multinational, randomized, double-blind, placebo-controlled induction and maintenance study to evaluate the efficacy and safety of CC- 93538 in adult and adolescent participants…
- Trial name
- NCT04753697
- Testing
- CC-93538
- Where
- 212 sites in United States, Argentina and 13 more
- Volunteers
- 430 people
- Sponsor
- Celgene
Asthma
Mechanisms of Adverse Effects of Long-Acting Beta-Agonists in Asthma
This study aims to elucidate the pathophysiological mechanisms underlying the adverse effects associated with the use of long-acting beta-agonists (LABAs) in asthma.
- Trial name
- MAELABA (NCT04503460)
- Testing
- Salmeterol Xinafoate, Salmeterol Fluticasone
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- Imperial College London
Dermatitis, Atopic
Clinical Effect, Safety and Tolerability of GSK1070806 in Atopic Dermatitis
This study will evaluate efficacy and safety of GSK1070806 in moderate to severe atopic dermatitis (AtD) participants.
- Trial name
- NCT04975438
- Testing
- GSK1070806
- Where
- 11 sites in United States, Canada
- Volunteers
- 34 people
- Sponsor
- GlaxoSmithKline
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