Clinical trials: Immediate Effect
Neuromuscular Subluxation of Joint, Manual Therapy
Immediate Effect of Cervical and Sacroiliac Manipulation on the Autonomic Nervous System and Balance
The aim of this study is to investigate the immediate effects of high-velocity low-amplitude (HVLA) chiropractic manipulation on the autonomic nervous system and baropodometric parameters.
- Conditions
- Neuromuscular Subluxation of Joint, Manual Therapy, Autonomic Nervous System Activity
- Trial name
- CSMPAANS (NCT06642688)
- Testing
- Sacroiliac Joint Manipulation, Cervical Spine Manipulation
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- SEFA HAKTAN HATIK
Asthma
Study to Evaluate GSK2190915 in Subjects With Mild Asthma
This study will evaluate the safety and effect of repeat oral doses of GSK2190915 on lung function in mild asthmatics using a number of clinical and biological markers of efficacy.
- Trial name
- NCT00812773
- Testing
- GSK2190915
- Where
- 3 sites in United Kingdom
- Volunteers
- 17 people
- Sponsor
- GlaxoSmithKline
Placental Transfusion, Stem Cells
Placental Transfusion Methods and Stem Cells
To measure the levels of endothelial progenitor cells and CD34+ hematopoietic stem cells levels, and placental residual volume by delayed cord clamping, umbilical cord milking or immediate cord clamping in newborns at different…
- Trial name
- NCT03983902
- Testing
- Delayed cord clamping, Umbilical cord milking, Immediate cord clamping
- Volunteers
- 96 people
- Sponsor
- Ankara University
Vision Screening, Amblyopia
Assuring Ophthalmologic Follow up
The goal of this study is to quantify the improvement in completed ophthalmology referrals and quantify the number of children identified and treated for amblyopia or pre amblyopic strabismus resulting from the implementation of…
- Trial name
- NCT04959422
- Testing
- Active scheduling
- Where
- United States
- Sponsor
- Dartmouth-Hitchcock Medical Center
Urticaria Chronic
Mediterranean and Low-Histamine Diets for Pediatric Chronic Spontaneous Urticaria
Chronic spontaneous urticaria (CSU) is a chronic inflammatory skin disease that can substantially impair quality of life in children and adolescents.
- Trial name
- NCT07765979
- Testing
- Low-Histamine Diet, Mediterranean Diet
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people
- Sponsor
- Saglik Bilimleri Universitesi
Atopic Dermatitis
Effect of Galactooligosaccharides on Incidence of Atopic Manifestations in Infants
Addition of prebiotic galactooligosaccharides to hypoallergenic starter formula would lead to decreased allergic (atopic) symptoms in nonbreastfed infants with a positive history of allergy in family
- Trial name
- NCT02077088
- Testing
- galactooligosaccharide
- Where
- Czechia
- Volunteers
- 120 people
- Sponsor
- Humana Co.Ltd.
Atopic Dermatitis, Skin Diseases
Effect of Lipikar Baume AP+M on Quality of Life and Pain of Adults With Dryness or Severe Xerosis
This study aims at evaluating the effect of a topical product on the improvement of quality of life and pain of patients suffering from atopic dermatitis or other skin diseases with dryness or severe xerosis.
- Trial name
- NCT05765461
- Where
- 7 sites in Croatia, Germany and 5 more
- Volunteers
- 4,631 people
- Sponsor
- Cosmetique Active International
Allergic Rhinitis
Study to Assess the Absorption and Tolerability of Intranasal Ketorolac Tromethamine and to Assess the Effects of Oxymetazoline Hydrochloride and Fluticasone Propionate on the Absorption and Tolerability of Intranasal Ketorolac Tromethamine in Participants With Allergic Rhinitis
This was an open label, three way study in participants with symptomatic allergic rhinitis. The following 3 treatments were administered to each subject during dosing periods 1, 2 and 3, respectively: Treatment A: Single…
- Trial name
- NCT01365650
- Testing
- Ketorolac Tromethamine, Oxymetazoline Hydrochloride, Fluticasone Propionate
- Where
- Australia
- Volunteers
- 24 people
- Sponsor
- Egalet Ltd
Asthma, Allergic, Asthma
IL13 Signaling in Allergic Asthma
This study will investigate the role of dupilumab in the treatment of asthma with comorbid obesity. It is hypothesized that in airway epithelial cells, unique transcriptomic and proteomic expression patterns distinguish allergic…
- Conditions
- Asthma, Allergic, Asthma, Obesity
- Trial name
- NCT05478824
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Duke University
Asthma
Study to Explore the Effects of Two Hour Inhalation of Ultrafine Carbon Black Particles on Airway Inflammation in Asthmatics
The aim of the study is to test the hypothesis that the allergic airway inflammation in asthmatic patients will be enhanced after exposure to ultrafine particles (UFP).
- Trial name
- NCT00527462
- Testing
- Bronchoscopy, Exposure to ultrafine carbon black particles
- Where
- Germany
- Volunteers
- 15 people
- Sponsor
- Fraunhofer-Institute of Toxicology and Experimental Medicine
Stroke
Immediate Effects of Ankle MWM and Taping on Gait and Balance in Stroke Patients
Disorders caused by stroke may lead to significant limitations, especially in ankle range of motion, and may cause impairments in walking and balance functions.
- Trial name
- NCT06318624
- Testing
- Mobilisation with Movement and Taping
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Kutahya Health Sciences University
Chronic Spontaneous Urticaria
Phase 2, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Effects of EP262 in Subjects With Chronic Spontaneous Urticaria
Phase 2, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Effects of EP262 in Subjects with Chronic Spontaneous Urticaria
- Trial name
- CALM-CSU (NCT06077773)
- Testing
- Oral EP262
- Where
- 48 sites in United States, Canada and 4 more
- Volunteers
- 113 people
- Sponsor
- Escient Pharmaceuticals, Inc
Atopic Dermatitis
Evaluating the Effects of Tradipitant vs. Placebo in Atopic Dermatitis (EPIONE2)
This is a multicenter, randomized, double-blind, placebo-controlled study to be conducted in the United States in subjects with atopic dermatitis.
- Trial name
- NCT04140695
- Testing
- Tradipitant
- Where
- 51 sites in United States
- Volunteers
- 87 people
- Sponsor
- Vanda Pharmaceuticals
Seasonal Allergic Rhinitis
4"S" - Seasonal Symptoms Suppression Study
ASIT naïve patients sensitized to grass pollens will be recruited for the study. All of them will be instructed to treat bothersome in-season symptoms when they appear (on as needed, pro re nata basis) with rescue medication.
- Trial name
- 4"S" (NCT02557269)
- Testing
- Xylometazoline - intranasal application, Azelastine - intranasal application, Mometasone furoate - intranasal application
- Where
- Bulgaria
- Volunteers
- 60 people
- Sponsor
- Association Asthma, Bulgaria
Asthma
A Phase 4, Randomized, Double-blind, Placebo-controlled, Multicenter, Parallel-group Study of the Effect of Dupilumab on Sleep Disturbance in Patients With Uncontrolled Persistent Asthma
Primary Objective: To assess the effect of dupilumab on sleep Secondary Objectives: To evaluate the effect of dupilumab on additional participant reported sleep outcomes To evaluate the effect of dupilumab on objective sleep…
- Trial name
- MORPHEO (NCT04502862)
- Testing
- SAR231893
- Where
- 55 sites in United States, Argentina and 9 more
- Volunteers
- 202 people
- Sponsor
- Sanofi
Asthma
Effects of L-arginine Supplementation in Adults With Moderate to Severe Asthma
Nitric oxide is an important marker of airway inflammation in asthma. Nitric oxide may have a protective role in patients with moderate to severe asthma.
- Trial name
- NCT00280683
- Testing
- L-arginine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, Davis
Allergic Rhinitis, Allergic Rhinitis (AR)
Effect of Combined Probiotics and Vitamin D on Symptoms of Allergic Rhinitis
The goal of this clinical trial is to learn if taking probiotics, vitamin D, or both together can help lower symptoms of allergic rhinitis (AR) and improve quality of life in adults.
- Trial name
- NCT07115342
- Testing
- Standard Allergic Rhinitis Treatment, Combined Vitamin D and Probiotics Supplementation
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Tanta University
Prone vs Supine Effects on Respiratory Outcomes
Prone or Supine Effect After Caesarean Delivery on Respiratory Outcomes in Full Term Infants
Investigators will compare 500 full term babies delivered by SCD randomized into two groups, prone or supine position. Investigators will use a Panda warmer with built in Nellcor pulse oximeter.
- Trial name
- NCT02692573
- Testing
- positioning
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Montefiore Medical Center
Seasonal Allergic Rhinitis
Effects of Imatinib in Subjects With Seasonal Allergic Rhinitis and Who Are Sensitive to Timothy Grass Pollen
This study will assess the effects of Imatinib on allergic inflammation following repeated nasal allergen challenge in subjects with seasonal allergic rhinitis sensitive to Timothy grass pollen.
- Trial name
- NCT00426179
- Testing
- Imatinib
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Novartis
Atopic Dermatitis
Effect of Pollen Challenges on Dermal Symptoms in Patients With Atopic Dermatitis
This is a mono-center, randomized, double-blind, placebo-controlled, parallel-group study to assess the effect of challenges with dactylis glomerata pollen in an environmental challenge chamber on dermal symptoms in patients…
- Trial name
- Neurop (NCT01475994)
- Testing
- Grass pollen : Dactylis glomerata, Challenge with clean air
- Volunteers
- 18 people
- Sponsor
- Fraunhofer-Institute of Toxicology and Experimental Medicine
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