Clinical trials: Immediate Effect
Muscle Weakness
The Immediate Effect of Combined Terminal Knee Extension Exercise With Audible Cues
Typically, patients perform TKE by themselves after exercise prescription. The investigators thought that a lack of attention and preferred speed of patients might not provide the best outcome.
- Trial name
- NCT06565325
- Testing
- Exercise + Audible Cues, Exercise
- Where
- Thailand
- Volunteers
- 30 people
- Sponsor
- Mahidol University
Bronchial Asthma, Signs and Symptoms, Respiratory
The Effect of Air Pollution on Lung Health Among School Children Living in Haifa Bay Region
Haifa bay region is located close to a major industrial zone. The aim of the study is to evaluate the health status of school children living in Haifa bay region.The health status will be evaluated using health questionnaires and…
- Conditions
- Bronchial Asthma, Signs and Symptoms, Respiratory, Allergy
- Trial name
- NCT00717899
- Testing
- Spirometry (Pony spirometer)
- Where
- Israel
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Carmel Medical Center
Massage, Asthma Patients
The Effect of Deep Tissue Massage on Respiratory Parameters in People With Asthma
Bronchial asthma, as a chronic inflammatory disease of the respiratory tract, significantly reduces the quality of life of patients.
- Trial name
- NCT06893445
- Testing
- Deep Tissue Massage, Classic massage
- Where
- 2 sites in Poland
- Volunteers
- 40 people
- Sponsor
- Jagiellonian University
Atopic Dermatitis
Effect of Probiotic Bifidobacterium Bifidum PRL 2010 in the Prevention of Atopic Dermatitis in Children
This study evaluates the effect of supplementation with Bifidobacterium bifidum PRL2010 during pregnancy in preventing atopic dermatitis in children.
- Trial name
- NCT06809465
- Testing
- Bactopral®, Plcebo
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Liaquat University of Medical & Health Sciences
Asthma
Study to Assess Airway Inflammation Effects of FlutiForm® pMDI Low and High Dose in Adults With Mild to Moderate Asthma
This is a dose-response study to determine how various measurements of airway inflammation respond to high and low dose FlutiForm®, and compared to placebo.
- Trial name
- FLT2503 (NCT00995800)
- Testing
- Fluticasone propionate / Formoterol fumarate
- Where
- Germany
- Volunteers
- 46 people
- Sponsor
- Mundipharma Research Limited
Hamstring Shortness
Acute Effects of Foam Roller and Mulligan Technique on Hamstring Flexibility
The hamstring muscle group is located at the back of the thigh. Due to its structure and people's habits, shortness in this muscle group is frequently observed.
- Trial name
- NCT07078734
- Testing
- Foam roller, Therapist-assisted Mulligan Straight Leg Raise
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Adverse Reaction to Drug, Allergic Reaction to Contrast Media
Assessment of Immediate Adverse Reactions From Dotarem in Children Under 2 Years of Age
Our primary outcome is to assess the safety of Dotarem in children <2 years old up to 24 hours after Dotarem injection. Patients will be monitored for any adverse events that occur for 2 hours following the completion of the MRI…
- Trial name
- NCT02609919
- Testing
- Gadoteric Acid
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- St. Louis University
Airway Obstruction, Asthma
Effects of Combined Respiratory Muscle Training and Steam Inhalation
The purpose of this investigation is to obtain more information on the efficacy and safety of respiratory training methods with WellO2 in patients with asthma and COPD.
- Conditions
- Airway Obstruction, Asthma, COPD
- Trial name
- NCT04584398
- Testing
- Respiratory muscle training with steam inhalation
- Where
- Finland
- Volunteers
- 60 people
- Sponsor
- WellO2 Oy
Patellofemoral Pain Syndrome
Immediate Effects of Ankle Mobilization on Dorsiflexion Range of Motion in Women With Patellofemoral Pain.
Anterior Knee Pain or Patellofemoral Pain (PFP) is one of the most common disorders that affecting knee in the physically active population, being a condition that typically presents as diffuse knee pain in the anterior region…
- Trial name
- Mestrado (NCT03281421)
- Testing
- Manual Therapy
- Where
- Brazil
- Volunteers
- 117 people
- Sponsor
- Universidade Federal do Ceara
Atopic Dermatitis
The Purpose of This Study is to Evaluate the Effects of Ruxolitinib Cream on Adults With Atopic Dermatitis Experiencing Sleep Disturbance.
The purpose of the study is to evaluate the effect of ruxolitinib cream on sleep disturbances with participants with Atopic Dermatitis.
- Trial name
- MORPHEUS (NCT05696392)
- Testing
- ruxolitinib cream
- Where
- 30 sites in United States
- Volunteers
- 47 people
- Sponsor
- Incyte Corporation
Rectal Cancer
Effect of a Post-operative Protocol of Early Mobilization on Functional Recovery and Postoperative Complications After Immediate Internal Pudendal Artery Perforator Flap Reconstruction for Irradiated Abdominoperineal Resection Defects: a Prospective, Randomized and Controlled Clinical Study.
Major abdominal oncology surgery is associated with substantial postoperative loss of functional capacity, and exercise may be an effective intervention to improve outcomes.
- Trial name
- NCT04795609
- Testing
- Early mobilization strategy adapted after immediate internal pudendal artery perforator flap reconstruction for abdominoperineal resection (intervention group).
- Where
- Brazil
- Volunteers
- 32 people
- Sponsor
- Instituto do Cancer do Estado de São Paulo
Obesity, Asthma
Bariatric and Obstructive Lung Disease Study II
The prevalence of obesity and asthma has significantly increased over the past two decades. The purpose of this study is to try and understand the mechanism by which obesity leads to airway hyperresponsiveness (AHR), one of the…
- Trial name
- BOLD II (NCT01127399)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Chronic Asthma
The Effect of Prasugrel on Bronchial Hyperreactivity and on Markers of Inflammation in Patients With Chronic Asthma
Cysteinyl leukotrienes (cys-LTs) are lipid inflammatory mediators that abound in mucosal inflammation and play a validated role in the pathogenesis of human asthma.
- Trial name
- PRINA (NCT01305369)
- Testing
- Prasugrel
- Where
- Italy
- Volunteers
- 26 people
- Sponsor
- University of Milan
Eczema, Atopic Dermatitis
A Clinical Trial to Evaluate the Effects of Rejuvaskin Eczema Body Wash and Skin Recovery Cream in Adults With Eczema-Prone Skin
This is a single-arm, open-label, decentralized (fully remote) clinical trial evaluating the tolerability and self-perceived skin effects of Rejuvaskin Eczema Body Wash and Skin Recovery Cream in 35 adults aged 18-65 with…
- Conditions
- Eczema, Atopic Dermatitis, Eczema-Prone Skin
- Trial name
- NCT07700745
- Testing
- Rejuvaskin Eczema Body Wash
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Rejuvaskin
Healthy Participants
Relative Bioavailability Study of a Modified-Release Formulation of PF-06865571 in Healthy Adult Participants
This study is an open-label, randomized, single-dose, 4-period, 4-sequence, crossover study in a single cohort of approximately 12 healthy adult participants.
- Trial name
- NCT04044053
- Testing
- PF-06865571 400 mg Immediate Release (IR) in Fed State, PF-06865571 50 mg Modified Release (MR) in Fed State, PF-06865571 400 mg MR in Fed State
- Where
- Belgium
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Pfizer
Muscle Fatigue, Healthy Adult
Recovery After Fatigue in Young Athletes: Comparison Between TECAR Therapy and Cycle Ergometer"
The goal of this clinical trial is to compare two recovery methods after fatigue in young athletes. It aims to find out if tecar therapy (TECAR) or cycle ergometer exercise can improve recovery after intense physical activity and…
- Trial name
- NCT07547566
- Testing
- Tecar therapy (capacitive mode), Active recovery using cycle ergometer
- Where
- Spain
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Maimónides Biomedical Research Institute of Córdoba
Asthma
Effect of Benralizumab on Airway Remodeling in Asthma
The anti-interleukin (IL)-5 receptor benralizumab inhibits eosinophilic inflammation but its potential effect on airway remodeling remains unknown.
- Trial name
- BENRAMOD (NCT04365205)
- Testing
- Endobronchial biopsy
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Asthma
A Phase 2a Study to Evaluate the Effects of Sirukumab in Subjects With Severe Poorly Controlled Asthma
Sirukumab is a fully human anti interleukin (IL)-6 immunoglobulin G1-kappa monoclonal antibody (MAb) which is in development for the treatment of rheumatoid arthritis (RA).
- Trial name
- NCT02794519
- Testing
- Sirukumab, Rescue medication
- Where
- 8 sites in United States, Spain
- Sponsor
- GlaxoSmithKline
Psoriasis Vulgaris
LP0058-1005 - A Open-Label, Four-Way Crossover and Food-Effect Study of LEO 32731 in Healthy Subjects
LEO 32731 ("Study Drug") is an investigational drug which is being developed by LEO Pharma A/S ("the Sponsor"), with an aim to help people with skin conditions called psoriasis.
- Trial name
- NCT02126371
- Testing
- LEO32731
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- LEO Pharma
Morbid Obesity
Effect of Boussignac CPAP Ventilation on PaO2 and PaO2/FiO2 Ratio in Morbidly Obese Patients Undergoing Bariatric Surgery
The purpose of this study is to determine if the application of Boussignac continuous positive airway pressure (CPAP) immediately after extubation improves PaO2 and PaO2/FiO2 ratio in morbidly obese patients undergoing gastric…
- Trial name
- NCT02297828
- Testing
- Boussignac CPAP, Venturi face mask
- Where
- Portugal
- Volunteers
- 24 people
- Sponsor
- Centro Hospitalar do Porto
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