Clinical trials: Immediate Effect
Sleep Inertia, Caffeine
Delayed-release Bedtime Caffeine and Sleep Inertia Symptoms Immediately Upon Awakening
Sleep inertia (sometimes also referred to as sleep drunkenness) is a disabling state of increased sleepiness, impaired mood and reduced vigilance immediately upon awakening.
- Conditions
- Sleep Inertia, Caffeine, Placebo
- Trial name
- NCT04975360
- Testing
- Caffeine
- Where
- Switzerland
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Asthma (Diagnosis)
ADO-5030 in Bronchoconstriction Challenge, Phase 1b
This is a Phase 1 study to learn about the safety and pharmacokinetics of the study drug in patients with asthma and whether the study drug has effect during a respiratory challenge.
- Trial name
- NCT07281274
- Testing
- ADO-5030
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Adovate
Cervical Radiculopathy, Vertigo
Effect of Cervical Traction on Balance in Cervical Radiculopathy Patients
A cross-over randomized trial aiming to assess the immediate effect of cervical traction on balance disorders among patients with common cervical neuropathy.
- Trial name
- NCT04598113
- Testing
- Cervical Traction Device
- Where
- Tunisia
- Volunteers
- 20 people
- Sponsor
- University of Monastir
Manual Therapies, Respiratory Muscle Training
Effects of Manual Therapy and Respiratory Muscle Training on the Maximal Inspiratory Pressure in Patients With Asthma
The aim of this study is to assess if an intervention of manual therapy and motor control exercises combined with an inspiratory muscle training program is more effective than an inspiratory muscle training program alone in…
- Conditions
- Manual Therapies, Respiratory Muscle Training, Exercise Therapy, Inspiratory Capacity
- Trial name
- NCT02690831
- Testing
- Inspiratory Muscle training (IMT), IMT + Manual Therapy and Motor Control Exercise, Powerbreathe
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universidad Autonoma de Madrid
Contraception, Newborn
Effect of t of the Etonogestrel Releasing Implant on Infant Growth and Development
This study aims to assess whether there is change in the growth and development of newborns whose mothers will have a etonogestrel (ENG) releasing implant inserted in the first 24 to 48 hours of delivery compared with those with…
- Conditions
- Contraception, Newborn, Child Development, Growth
- Trial name
- NCT02469454
- Testing
- early insertion, conventional insertion
- Where
- Brazil
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Asthma
The Effect of Pranayama Breathing Technique on Asthma Control, Pulmonary Function and Quality of Life
Most of the asthma patients prefer complementary and integrative applications as they continue to experience asthma symptoms despite pharmacological treatment.
- Trial name
- NCT04110951
- Testing
- Pranayama Breathing Technique, Relaxation technique
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- TC Erciyes University
Asthma
Effect of Sex Hormone During the Menstrual Cycle on Capsaicin Evoked Cough Responses
The study aim is to investigate if changes in sex hormones during the menstrual cycle affects cough sensitivity in females and males with mild allergic asthma.
- Trial name
- CASH (NCT04233762)
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- McMaster University
Atopic Dermatitis (Eczema)
The Effects of a Botanical Moisturizer and an Unscented Soap on Eczema and Itch
The purpose of this study is to examine the effects of a botanical moisturizer and an unscented soap on eczema severity, itch, mood, and various skin measures (such as skin hydration) in those with mild to moderate eczema.
- Trial name
- NCT06804070
- Testing
- Botanical Moisturizer + Unscented Soap
- Where
- Poland
- Volunteers
- 34 people
- Sponsor
- Codex Labs Corporation
HIV Infections, AIDS-Related Opportunistic Infections
When to Start Anti-HIV Drugs in Patients With Opportunistic Infections
The purpose of this study is to evaluate the effect of starting anti-HIV drugs in HIV infected patients who are being treated for opportunistic infections (OIs).
- Trial name
- NCT00055120
- Testing
- Emtricitabine/tenofovir disoproxil fumarate, Lopinavir/ritonavir, Stavudine
- Where
- 45 sites in United States, Puerto Rico and 1 more
- Volunteers
- 283 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Allergic Rhinitis
Intralymphatic Immunotherapy for House Dust Mite, Dog, and Cat Allergy Using Tyrosine S® in Allergic Rhinitis
The investigators will perform double-blinded placebo-controlled randomized clinical trial which evaluates the efficacy and safety of allergen-specific intralymphatic immunotherapy (ILIT) for allergens including Dermatophagoides…
- Trial name
- ILIT-T (NCT02665754)
- Testing
- ILIT with extract of causal allergen, ILIT with normal saline, Rescue medication for allergic rhinitis
- Where
- South Korea
- Volunteers
- 32 people
- Sponsor
- Gachon University Gil Medical Center
Asthma
Effect of a Pharmaceutical Intervention on the Level of Control of the Asthmatic Patient
Measurement of disease control, treatment adherence and patient knowledge of his/her medication in patients that are receiving a pharmaceutical intervention compared with those patients who receive regular pharmaceutical care.
- Trial name
- NCT01085474
- Testing
- 1, 2
- Where
- 2 sites in Spain
- Volunteers
- 384 people
- Sponsor
- AstraZeneca
Asthma
Study to Evaluate Efficacy & Safety of Tralokinumab in Subjects With Asthma Inadequately Controlled on Corticosteroids
A Multicentre, Randomized, Double-blind, Parallel Group, Placebo Controlled, 12-Week, Phase 2 Study to Evaluate the Effect of Tralokinumab on Airway Inflammation in Adults with Asthma Inadequately Controlled on Inhaled…
- Trial name
- MESOS (NCT02449473)
- Testing
- Tralokinumab
- Where
- 15 sites in Canada, Denmark and 1 more
- Volunteers
- 79 people
- Sponsor
- AstraZeneca
Atopic Dermatitis, Eczema
Evaluating the Effect of Bathing Additives in Atopic Dermatitis
This proposed project will be an open-label, split-arm, randomized controlled pilot study. Up to 60 patients diagnosed with atopic dermatitis (eczema) will be enrolled in the study.
- Trial name
- NCT04001855
- Testing
- Dilute vinegar (acetic acid), Dilute bleach
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Arizona
Primary Dysmenorrhea
Immediate Effects of Kinesio Taping in Primary Dysmenorrhea
Primary dysmenorrhea is characterized by recurrent, cramping lower abdominal pain during menstruation and affects approximately 50% to 90% of women.
- Trial name
- NCT06990815
- Testing
- Kinesio Taping
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Okan University
the Augmentation of Labial Defective Wall in Fresh Extraction Socket
Augmentation of Facial Wall in Defective Fresh Extraction Site for Immediate Implant Placement
The study is performed to clinically and radiographically assess the efficacy of using enriched bone graft combined with slowly resorbable membrane on bone quality in immediate implant placement in extraction socket in cases with…
- Trial name
- NCT06867848
- Testing
- laminar bone membrane for labial bone augmentation
- Where
- Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Nuhayra Ashour Muhammed
Pulmonary Disease, Chronic Obstructive, Asthma
Tolerability of Metoprolol-Succinate-ER and Carvedilol in COPD
Use of beta-blockers has proven beneficial in patients with hypertension, heart failure, and in people who have suffered a heart attack.
- Conditions
- Pulmonary Disease, Chronic Obstructive, Asthma, Adverse Effect of Beta-adrenoreceptor Antagonists
- Trial name
- NCT03370835
- Testing
- Metoprolol succinate ER, Carvedilol
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- VA Greater Los Angeles Healthcare System
Asthma
Investigation of Intravenous (IV) Administration of an Approved Drug (MK-0476, Montelukast Sodium) for Acute Asthma (MK-0476-288)
The purpose of this study is to evaluate improved results of treatment for patients entering an emergency department with asthma attacks when given an investigational IV administration of an approved drug (MK-0476, montelukast…
- Trial name
- NCT00092989
- Testing
- montelukast sodium
- Volunteers
- 650 people
- Sponsor
- Organon and Co
Asthma
Effect of Omalizumab in Patients With Severe Persistent Non-atopic Uncontrolled Asthma
This study will assess the change in the expression of FcεRI receptors of blood basophils and dendritic cells after 16 weeks of treatment with omalizumab as compared with placebo, in adult patients with non-atopic severe…
- Trial name
- NATAIR (NCT01007149)
- Testing
- omalizumab
- Where
- 10 sites in France
- Volunteers
- 79 people
- Sponsor
- Novartis Pharmaceuticals
Allergic Rhinitis, Inflammation
Airway Inflammation in Children With Allergic Rhinitis and Intervention
The purpose of this study is to determine whether treating upper airway with intranasal corticosteroids in children with allergic rhinitis and no asthma may bring favors in reducing lower airway inflammation and improving small…
- Conditions
- Allergic Rhinitis, Inflammation, Respiratory Tract Diseases, Hypersensitivity
- Trial name
- NCT02352168
- Testing
- Budesonide nasal spray
- Where
- China
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Guangzhou Institute of Respiratory Disease
Asthma
Comparison of Anti-inflammatory Effects of Seroflo and Seretide in Patients With Asthma
The purpose of this study is to test hypothesis if Sereflo (ICS/LABA) could reduce airway inflammation in asthmatic patients in the same as Seretide.
- Trial name
- NCT01274325
- Testing
- Sereflo, Seretide
- Where
- 2 sites in Thailand
- Volunteers
- 51 people
- Sponsor
- Mahidol University
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