Clinical trials: Immobility
Immobilization, Tonic, Fasting
A New Model of Acute Febrile Disease
The investigators want to establish a new model of acute febrile disease by mimicking the conditions seen in hospitalized patients in regards to inflammation, immobilisation and fasting.
- Conditions
- Immobilization, Tonic, Fasting, Endotoxemia, Metabolism
- Trial name
- NCT03158363
- Testing
- LPS, 36 hour immobilization and fast
- Where
- Denmark
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Sarcopenia
Neuromuscular Electrical Stimulation Study
In this study, the investigators will use feasibility RCT design to determine whether it is justifiable to conduct a large-scale clinical trial of neuromuscular electrical stimulation with or without additional protein…
- Trial name
- IMMI (NCT04792307)
- Testing
- Neuromuscular electrical stimulation , no high protein ice cream supplementation
- Volunteers
- 66 people
- Sponsor
- Nottingham University Hospitals NHS Trust
Immobility Syndrome, Fall
Goal-directed Mobilization of Medical Inpatients
Immobilization in general internal medicine inpatients is a major contributor to morbidity and mortality. Goal-directed mobilization (GDM) may improve mobility.
- Conditions
- Immobility Syndrome, Fall, Delirium, Sarcopenia
- Trial name
- GoMob-in (NCT04760392)
- Testing
- Goal-directed mobilization
- Where
- Switzerland
- Volunteers
- 160 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
In-hospital Mobility, Geriatric
Hospital-Induced Immobility
Inactivity and bedrest during hospitalisation have numerous negative consequences, and it is especially important that older patients are mobile during hospitalisation.
- Conditions
- In-hospital Mobility, Geriatric, Immobilization
- Trial name
- NCT05926908
- Testing
- A Mobilisation Initiative, Focus Group Interviews, Formal Education
- Where
- Denmark
- Volunteers
- 596 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Fracture
Assessment of Cortical Plasticity Following Short Term Limb Immobility
The proposed project will study the consequence of short term limb immobility on the patterns of brain activity using functional imaging (fMRI)
- Trial name
- NCT00647374
- Testing
- this is an observational study
- Where
- Israel
- Sponsor
- Hadassah Medical Organization
Immobility Syndrome, Pressure Ulcer
Novel Support Surface to Alleviate Pressure Ulcer
A prototype support surface has been designed which aims to successfully redistributes the pressures exerted and provides sufficient support to human soft tissue We want to prove the effectiveness of the prototype support surface…
- Conditions
- Immobility Syndrome, Pressure Ulcer, Pressure Injury
- Trial name
- NCT04251897
- Testing
- Novel support surface
- Where
- Singapore
- Volunteers
- 10 people
- Sponsor
- Tan Tock Seng Hospital
Mobility Limitation, Exercises
Effectiveness of Mobility Exercises in Resistance-Trained Males With Shoulder Immobility in Different Age Groups
The shoulder is a dynamic and mobile joint between the arm and the trunk. The movement of the joint in three dimensions performs complex movements in almost every activity of daily life.
- Trial name
- NCT05450666
- Testing
- mobility exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Brain Injuries, Dementia
ACT-ICU Study: Activity and Cognitive Therapy in the Intensive Care Unit
Intensive care unit (ICU) hospitalization saves lives but often does so at a high personal cost to ICU survivors who frequently experience significant cognitive impairment and an array of physical and functional disabilities that…
- Conditions
- Brain Injuries, Dementia, Myopathies, Muscle Disorders
- Trial name
- ACT-ICU (NCT01270269)
- Testing
- Behavioral: Physical and functional rehabilitation, Behavioral: Cognitive, physical, & functional rehabilitation
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- Vanderbilt University
Breast Cancer, Mastectomy; Lymphedema
Myofascial Massage for Pain and Immobility Following Breast Cancer Surgery
About 25-50% of women who undergo breast cancer surgery develop persistent chest wall pain and shoulder mobility limitations following surgery.
- Conditions
- Breast Cancer, Mastectomy; Lymphedema, Pain, Shoulder, Mobility Limitation
- Trial name
- NCT04233385
- Testing
- Myofascial Massage, Light Touch
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- MetroHealth Medical Center
Ovarian Cancer, Ovarian Carcinoma
Exercise as a Preventive Agent to Combat Immobility in Patients With Ovarian or Endometrial Cancers Receiving Chemotherapy
The purpose of this research is to determine whether a 16-week virtually supervised aerobic and resistance exercise program is feasible in patients receiving first-line chemotherapy after surgery for ovarian or endometrial cancer…
- Conditions
- Ovarian Cancer, Ovarian Carcinoma, Ovarian Cancer Stage IV, Ovarian Cancer Stage III
- Trial name
- NCT04997096
- Testing
- Exercise, Attention Control
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Dana-Farber Cancer Institute
Acute Respiratory Failure, Encephalopathy
Novel Arm Restraint For Critically Ill Patients To Reduce Immobility, Sedation, Agitation and Cognitive Impairment
This study evaluates a novel arm restraint compared with traditional soft wrist restraints in older critically ill patients. The primary outcome is upper extremity mobility measured by actigraphy, and secondary outcomes include…
- Conditions
- Acute Respiratory Failure, Encephalopathy, ARDS, Sepsis
- Trial name
- NCT04067622
- Testing
- Exersides
- Where
- 3 sites in United States
- Volunteers
- 58 people
- Sponsor
- University of Vermont
Muscular Atrophy, Immobility Syndrome
Mechanisms of Disuse Atrophy in Human Skeletal Muscle (iMOB)
Loss of muscle can be caused by a variety of stimuli and results in reduced mobility and strength and also impacts whole body health. Whilst it is known that muscles waste the process by which this occurs is not well understood.
- Trial name
- iMOB (NCT04199923)
- Testing
- Single leg immobilisation
- Where
- United Kingdom
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Deglutition Disorders, Impaired Cognition
Dysphagia in Elderly Medical Patients
Dysphagia in hospitalized elders is associated with less positive outcomes in rehabilitation, increased likelihood of readmission, increased comorbidity and mortality, and increased length of hospital stay.
- Conditions
- Deglutition Disorders, Impaired Cognition, Physical Activity, Complete Immobility Due to Frailty
- Trial name
- DEM (NCT01006330)
- Where
- Denmark
- Volunteers
- 110 people
- Sponsor
- Herlev Hospital
Inferior Turbinate Hypertrophy, Chronic Rhinosinusitis (CRS)
Efficacy of Lavender Aromatherapy on Anxiety and Pain Reduction During Awake Otolaryngologic Procedures
The purpose of this study is to evaluate the efficacy of lavender aromatherapy in adult patients undergoing awake otolaryngologic procedures in the outpatient clinic setting.
- Conditions
- Inferior Turbinate Hypertrophy, Chronic Rhinosinusitis (CRS), Rhinitis, Vasomotor, Thyroid Nodules
- Trial name
- NCT07299474
- Testing
- Lavender Aromatherapy
- Where
- United States
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Head and Neck Disorder, Head and Neck Cancer
Bevonescein for Improved Intraoperative Nerve Visualization to Improve Voice Outcomes in Thyroidectomy Patients
Bevonescein (ALM-488) is a novel fluorescein-containing peptide that is intended as a visualization adjunct for the real-time enhanced structural delineation of major nerves during Head and Neck surgery to potentially improve…
- Trial name
- NCT07631650
- Testing
- Bevonescein (ALM 488) Infusion
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Matthew Spector
Stroke, Acute, Venous Thromboembolism
GEKO Venous Thromboembolism Prevention Study
This multicentre, randomised geko™ venous thromboembolism (VTE) prevention study will prospectively collect clinical data on VTE occurrences in immobile patients after stroke, who will be randomised, on a 1:1 allocation, to…
- Conditions
- Stroke, Acute, Venous Thromboembolism, Deep Vein Thrombosis, Pulmonary Embolism
- Trial name
- NCT05476913
- Testing
- geko™ device
- Where
- 18 sites in United Kingdom
- Volunteers
- 1,200 people
- Sponsor
- Firstkind Ltd
Immobility and Weakness Associated With Long Intensive Care Unit Stays
Early Progressive Mobility in the CVICU: Assessing Current Status
The current study is proposed to assess the frequency and type of progressive mobility procedures currently performed in the CVICU The study will evaluate the type and frequency of progressive mobility orders, whether or not…
- Trial name
- NCT01295541
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Hill-Rom
Critical Illness
Early Rehabilitation in Critically Ill Children Pilot Study
Critically ill patients are often confined to bedrest, because of the nature of their illness. However, it has now been shown that prolonged bedrest and immobility, particularly in critically ill adults and children, can lead to…
- Trial name
- WeeHab in PCCU (NCT01531816)
- Testing
- Early Rehabilitation intervention
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- McMaster University