Clinical trials: Immobilization, open to volunteers
Motion Analysis, Biomechanical Parameters
The Impact of Shoulder Immobilization by Orthoses on Human Joint Biomechanics and Inter-joint Coordination
Shoulder joint orthoses are commonly used for patients with shoulder disorders to stabilize and protect shoulder joint after injury or surgery.
- Trial name
- Biomechanics (NCT07659054)
- Testing
- Shoulder immobilization by sling
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Lower Extremity Injuries, Venous Thromboembolism (VTE)
TRiP-cast Score Validation and Evaluation of Adherence to Preventive Anticoagulant Treatment in Patients With Lower Limb Trauma Requiring Immobilization
This is a prospective, multicenter, observational cohort study designed to externally validate the Trauma-Related Immobilization-related Prophylaxis (TRiP(cast)) score in Tunisian adults with acute lower-limb trauma requiring…
- Conditions
- Lower Extremity Injuries, Venous Thromboembolism (VTE), Deep Vein Thrombosis, Pulmonary Embolism
- Trial name
- TRiP-VALID (NCT07863115)
- Testing
- Low-Molecular-Weight Heparin (LMWH), Direct Oral Anticoagulants (DOACs), No Thromboprophylaxis Cohort
- Where
- Tunisia
- Volunteers
- 1,500 people
- Sponsor
- University of Monastir
Snake Bites, Snakebite
Analysis of the Efficacy of Pressure Pad vs Pressure Bandage Immobilisation for Snake Bite First Aid in Healthy Volunteers.
Snake bite affects thousands of Australians every year, but few die as a result due to high quality first aid and timely medical care.
- Conditions
- Snake Bites, Snakebite, Snake Envenomation, Snake Bite
- Trial name
- NCT07261982
- Testing
- Pressure bandage immobilisation first aid, Pressure pad first aid, Control - no first aid
- Where
- Australia
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Townsville University Hospital
Total Knee Arthroplasty
REST-Knee: A Pilot RCT of 72-Hour Knee Immobilization and Pain Outcomes
Postoperative pain following total knee arthroplasty (TKA) is often difficult to manage, particularly with the increasing use of outpatient surgery where patients recover at home.
- Trial name
- REST-Knee (NCT07511842)
- Testing
- Knee Extension Brace (Zimmer-type), Early Mobilization (Standard Care)
- Where
- Canada
- Volunteers
- 106 people
- Sponsor
- Université de Sherbrooke
Preterm Birth, Cervical Insufficiency
Bed Rest With a Short Cervix on Preterm Birth
Maternal AR has long been used to prevent PTB. However, definitions of AR vary widely, ranging from complete bed rest to partial limitation of physical activity for one or more hours daily.
- Conditions
- Preterm Birth, Cervical Insufficiency, Bed Rest, Pregnancy Complications
- Trial name
- BEWISE (NCT07577388)
- Testing
- Activity Restriction, No Activity Restriction
- Volunteers
- 6,000 people
- Sponsor
- Julie Glavind
Acromioclavicular Joint Injury, Acromioclavicular Joint Dislocation
Contralateral Resistance Training During Immobilization in Patients With Acromioclavicular Joint Injury
This randomized controlled trial aims to compare the effects of contralateral eccentric and concentric resistance training performed during the immobilization period following acromioclavicular joint injury.
- Trial name
- CROSS-ACD (NCT07628361)
- Testing
- Contralateral Eccentric Resistance Training, Contralateral Concentric Resistance Training
- Where
- Chile
- Volunteers
- 16 people
- Sponsor
- Universidad Nacional Andres Bello
Invasive Breast Cancer Early Stages, Ductal Carcinoma In Situ, DCIS
Personalized Prone Immobilization for Accelerated Partial Breast Radiotherapy
The goal of this clinical trial is to find out whether using a personalized breast holder (called VENUS SHELL™) can improve positioning and patient comfort during prone radiotherapy (radiotherapy given while the patient lies on…
- Trial name
- SHIELD (NCT07711847)
- Testing
- VENUS SHELL™ immobilization device
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- HeroSupport SA
Transcranial Direct Current Stimulation
Effects of Transcranial Direct Current Stimulation After Short-term Immobilization on Motor Learning and Hand Function in Healthy Young Adults
The purpose of the study is to investigate the effects of short-term braking on the motor learning and fine motor skills of healthy adults, and to analyze whether transcranial direct current stimulation can alleviate the effects…
- Trial name
- NCT07089056
- Testing
- transcranial direct current stimulation, immobilization
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Beijing Sport University
Foot Ankle Injuries
Is 6 Weeks Immobilization for a Chopart Injury Still State of the Art? Comparison Between Cast Immobilization Versus Functional Treatment
Treatment Arms for Randomization 1. Restrictive treatment: Immobilization in a cast or VACOped boot (lower leg boot with ankle immobilzation) for 6 weeks. Advantage: Provides stable conditions for fracture healing.
- Trial name
- NCT07477327
- Testing
- 6 weeks cast immobilization, Rigide sole
- Volunteers
- 70 people
- Sponsor
- Hôpital Fribourgeois
Head and Neck Cancer, Claustrophobia
Comparing Radiotherapy Immobilization Systems for Anxious HNC Patients
Background: Radiotherapy is a mainstay of treatment for ENT cancers, and its indication is frequent. Patients are positioned and immobilized using a thermoplastic mask, which is attached to the treatment table for the duration of…
- Conditions
- Head and Neck Cancer, Claustrophobia, Anxiety
- Trial name
- CRISP (NCT06257121)
- Testing
- OSMS position management
- Volunteers
- 15 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Thrombocytopenia, Immune Thrombocytopenia
Contribution of Anti-platelet Antibodies Identified With MAIPA Assay in the Demonstration of the Auto-immune Character of a Thrombocytopenia at Diagnosis
Immune thrombocytopenia (ITP) is an autoimmune disease but, paradoxically, and unlike other autoimmune diseases, antiplatelet antibodies are not used either for the diagnosis of the disease or for its prognosis.
- Conditions
- Thrombocytopenia, Immune Thrombocytopenia, Myelodysplasia
- Trial name
- APAT (NCT04800458)
- Testing
- Blood samples
- Where
- France
- Volunteers
- 225 people
- Sponsor
- University Hospital, Bordeaux
Muscle Weakness
Mitigating Neural Hypoexcitability and Weakness During Disuse in Women
Clinical trial The goal of this clinical trial is to learn how muscle weakness and atrophy develop during short periods of arm immobilization and whether a type of exercise called cross-education can help reduce these effects in…
- Trial name
- MiND (NCT07166198)
- Testing
- Wrist immobilization, Resistance training, Resistance training rehabilitation
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Kansas State University
Malignant Neoplasms
Body Composition and Setup Errors in Radiotherapy
This single-center prospective cohort study investigates the association between body composition parameters and setup errors in 120-150 patients receiving radiotherapy with thermoplastic mask immobilization.
- Trial name
- BODY-SET (NCT07676032)
- Volunteers
- 150 people
- Sponsor
- Shijiazhuang People's Hospital
Mitochondrial Energetics, Dietary Nitrate
Effect of Dietary Nitrate on Immobilization-induced Changes in Skeletal Muscle in Young Healthy Men
Diminished use of skeletal muscle, such as occurs with many chronic diseases (e.g., heart failure or cancer cachexia), denervation, bedrest, immobilization (e.g., limb casting or bracing), etc., is a common clinical condition…
- Conditions
- Mitochondrial Energetics, Dietary Nitrate, Disuse Atrophy (Muscle) of Lower Leg
- Trial name
- NCT07161973
- Testing
- Beetroot Juice - Active
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Indiana University
Restless Leg Syndrome
The Suggested Immobilization Test With Exploratory Heart Rate Variability Analysis for Diagnosis of Restless Legs Syndrome
Restless leg syndrome (RLS) is not uncommon and can also affect people's health and quality of life. Mainly, RLS is diagnosed based on clinical criteria subjectively.
- Trial name
- NCT07110961
- Testing
- A suggested immobilization test (SIT)
- Where
- Thailand
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Siriraj Hospital
Ankle Osteoarthritis, Ankle - Recurrent Dislocation
Early MOtion Total Ankle Artroplasty
Evaluate the clinical and radiographic results of patients undergoing total ankle arthroplasty and treated in the post-operative period in a randomized manner with early mobilization of the ankle joint or with cast immobilization…
- Conditions
- Ankle Osteoarthritis, Ankle - Recurrent Dislocation, Cartilage Disease, Ankle Arthropathy
- Trial name
- EMOTAA (NCT06525545)
- Testing
- early mobilizzation of the ankle
- Where
- Italy
- Volunteers
- 72 people
- Sponsor
- Istituto Ortopedico Rizzoli
Metacarpal Fracture, Phalanx Fracture
Intramedullary Screw Fixation Versus Closed Reduction and Percutaneous Pinning With Cast Immobilization
Broken bones in the hand are common injuries that can make it hard to move fingers, grip objects, and return to work. When these breaks happen in the long bones of the hand (called metacarpals and phalanges), surgery is often…
- Trial name
- GRIP (NCT07616947)
- Testing
- ORIF, IMSF, CRPP
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Spencer B Chambers
Infectious; Spondylitis
Prolonged Bed Rest Versus Early Raising in Vertebral Osteomyelitis
Infectious vertebral osteomyelitis are infectious diseases of the vertebral bone, intervertebral disc and/ or adjacent tissue. Most of cases are due to hematogenous dissemination of pathogen but direct inoculation is an aetiology…
- Trial name
- SPONDYL'UP (NCT04735081)
- Volunteers
- 200 people
- Sponsor
- Central Hospital, Nancy, France
Venous Thromboembolism, Deep Vein Thrombosis
RIVAroxaban Versus Low-molecular Weight Heparin in Patients With Lower Limb Trauma Requiring Brace or CASTing
Lower limb trauma requiring immobilization is a very frequent condition that is associated with an increased risk of developing venous thromboembolism (VTE).
- Conditions
- Venous Thromboembolism, Deep Vein Thrombosis, Pulmonary Embolism, Lower Limb Trauma
- Trial name
- RIVACAST (NCT06195540)
- Testing
- Rivaroxaban 10 MG, Low Heparin Molecular Weight
- Where
- 37 sites in France
- Volunteers
- 1,424 people
- Sponsor
- University Hospital, Angers
Prostate Cancer
Feasibility Trial of Single-Dose Radiotherapy for Localized Low and Intermediate Risk Prostate Cancer
The goal of this study is to assess the feasibility of high-dose radiotherapy (Single-Dose Radiotherapy, SDRT) of 24 Gy in patients with localized low and intermediate risk prostate cancer using a special system of internal and…
- Trial name
- FAST-ONE (NCT07112781)
- Testing
- Single Dose Radiotherapy
- Where
- Russia
- Volunteers
- 30 people
- Sponsor
- Branch Office of "Hadassah Medical Ltd"