Transcranial Direct Current StimulationNCT07089056
Effects of Transcranial Direct Current Stimulation After Short-term Immobilization on Motor Learning and Hand Function in Healthy Young Adults
A study testing transcranial direct current stimulation and immobilization in people with Transcranial Direct Current Stimulation, run by Beijing Sport University.
Trial summary
The purpose of the study is to investigate the effects of short-term braking on the motor learning and fine motor skills of healthy adults, and to analyze whether transcranial direct current stimulation can alleviate the effects of braking on motor learning and fine motor skills. Read more about this study
- Who is it for?
- Ages 18 to 25 yearsHealthy volunteers can take part
- Conditions the study is for
- Transcranial Direct Current Stimulation
- What is being tested?
- transcranial direct current stimulation and immobilization
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- Yes, some participants may receive a placebo
- How many people
- 60 participants
- Where
- No sites listed yet
- Study dates
- 21 Jul 2025to 1 Oct 2025
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 25 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- (1) age between 18 and 25 years;
- (2) normal or corrected-to-normal vision;
- (3) right-handedness.
Who cannot join
- (1) with history of pregnancy, cardiovascular disease, other physical impairments or illnesses;
- (2) with personal or family history of mental illness;
- (3) implanting any internal or external medical devices;
About this study
The purpose of the study is to investigate the effects of short-term braking on the motor learning and fine motor skills of healthy adults, and to analyze whether transcranial direct current stimulation can alleviate the effects of braking on motor learning and fine motor skills.
Read the detailed description
The purpose of the study is to investigate the effects of 16-hour short-term immobilization on the motor learning and fine motor skills of healthy adults, and to analyze whether transcranial direct current stimulation intervention can alleviate the effects of immobilization on motor learning and fine motor skills.
- Conditions
- Transcranial Direct Current Stimulation
- Being tested
- transcranial direct current stimulation, sham transcranial direct current stimulation, immobilization
- Keywords
- Transcranial direct current stimulation, immobilization, motor learning
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
transcranial direct current stimulationProcedure or surgery
The intervention will be conducted using a battery-powered stimulator (TCS-E2000, Shenzhen Yingchi Technology Co., Ltd) through a pair of saline-soaked sponge electrodes (5 cm × 5 cm).The stimulation intensity will be set at 2 mA. The stimulation will last for 20 minutes, with a 10 s fade-in period at the start and a 10-s fade-out period at the end of stimulation. The anodal electrode will be placed over the primary motor cortex (M1), and the reference electrode will be positioned at the center of the forehead.
sham transcranial direct current stimulationDevice
The intervention will be conducted using a battery-powered stimulator (TCS-E2000, Shenzhen Yingchi Technology Co., Ltd) through a pair of saline-soaked sponge electrodes (5 cm × 5 cm).The stimulation intensity will be set at 2 mA. The anodal electrode will be placed over the primary motor cortex (M1), and the reference electrode will be positioned at the center of the forehead for 20 minutes. However, there will be current only during the first 10 seconds and the last 10 seconds.
immobilizationProcedure or surgery
The researchers will use an upper limb fixation splint to fix the right upper limb of the participants, with the elbow joint flexed at 90 degrees, to ensure that all movements of the wrist, metacarpophalangeal joints, proximal interphalangeal joints, and interphalangeal joints are completely restricted. To avoid discomfort caused by the splint, soft bandages will be wrapped around the hand, and the splint will be adjusted to fit the shape of the hand. Ensure that the fingertips are visible to ensure good blood circulation. The subjects need to wear the upper limb fixation splint for 16 hours. Instruct the subjects to minimize movement and use of the right upper limb as much as possible. During the immobilization process, pay attention to checking if the participants have numbness or other discomfort, as well as whether the blood flow is good. If any adverse symptoms occur, the immobilization will be immediately terminated.
| Study group | Role | What they receive |
|---|---|---|
| Immobilization and Transcranial Direct Current Stimulation | Experimental | The participants' right hands will be immobilized for 16 hours, and they will receive 20 minutes of transcranial direct current stimulation before the immobilization period ends. Receives: Device: sham transcranial direct current stimulation; Procedure: immobilization |
| Immobilization and Sham Transcranial Direct Current Stimulation | Experimental | The participants' right hands will be immobilized for 16 hours, and they will receive 20 minutes of transcranial direct current stimulation before the immobilization period ends. Receives: Procedure: transcranial direct current stimulation; Procedure: immobilization |
| Blank control group | No intervention | Not described |
What is being measured
The primary outcome is the main question the study is designed to answer.
Sequence Reaction Time Task
The participants will sit in front of the laptop and placed their four right fingers on the four keys on the keyboard. In this task, a white circle appears above one of four horizontally arranged white squares on the computer screen with black background. Participans will be instructed to press the proper button on the response pad (buttons H, J, K, L) using the corresponding finger of the right hand (index finger for button H, middle finger for button J, ring finger for button K, and small finger for button L) when the white circle appeared at the left side, middle-left side, middle-right side, or right side of the computer screen, respectively. Each session consists of eight blocks, with each block comprising 120 trials.
Measured: Baseline; after one week
Secondary outcomes (2)
Purdue Pegboard Test
The Purdue Pegboard (model 32020; Lafayette Instrument Co., Lafayette,Indiana) performed the tests. The nail jacks were arranged in two parallel columns, and the nail, washer, and collar were placed in the four cups at the top of the plate before the experiment began. Subjects will be prompted to begin the test by using a nail to jack first with their right hand, then with their left hand, and finally with both hands simultaneously. Each segment was 30 s in duration, and the number of nails transferred by the participant was recorded. Finally, participants will assemble a nail, a washer, a collar and a washer on top of it, starting with their right hand in 1 minute. Each of the above sections was repeated three times to obtain an average score.
Measured: Baseline; after one week
Reach and grasp action test
The reach and grasp test included two parts: the fine grasp test and the gross grasp test. In the fine grip test, participants will be instructed to grasp a pencil with the tips of their thumb and index finger, and in the coarse grip test, they are instructed to grasp a tennis ball with their entire hand. Participants will seat in front of a table, and the tester placed the objects on the marked points. Participants began and ended the grasp task at the same location (30cm from the marker), and all performed the same posture (index finger in contact with thumb). Participants will complete the grasp task 15 times at their own pace.
Infrared motion capture system will be used to record 3D kinematic data during the reaching and grasping movements.
Measured: Baseline; after one week
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted28 Jul 2025
- Study start21 Jul 2025 (estimated)
- Primary completion15 Sep 2025 (estimated)
- Study completion1 Oct 2025 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Transcranial Direct Current StimulationStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Quadruple blind
- Who is masked
- Participant, Care provider, Investigator, Outcomes assessor
- Enrolment
- 60 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Beijing Sport University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07089056
- Sponsor's protocol ID
- 2023145H
- Status last verified
- Jul 2025
- First submitted
- 20 Jul 2025
- Last updated
- 30 Jul 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 30 Jul 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effects of Transcranial Direct Current Stimulation After Short-term Immobilization on Motor Learning and Hand Function in Healthy Young Adults
- ClinicalTrials.gov ID
- NCT07089056
- Acronym / sponsor ID
- 2023145H
- Conditions
- Transcranial Direct Current Stimulation
- Keywords
- Transcranial direct current stimulation, immobilization, motor learning
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 60 participants (estimated)
- Lead sponsor
- Beijing Sport UniversityUniversity, hospital or other
- Study start
- 21 Jul 2025 (estimated)
- Primary completion
- 15 Sep 2025 (estimated)
- Study completion
- 1 Oct 2025 (estimated)
- First posted
- 28 Jul 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The purpose of the study is to investigate the effects of short-term braking on the motor learning and fine motor skills of healthy adults, and to analyze whether transcranial direct current stimulation can alleviate the effects of braking on motor learning and fine motor skills.
Detailed description
The purpose of the study is to investigate the effects of 16-hour short-term immobilization on the motor learning and fine motor skills of healthy adults, and to analyze whether transcranial direct current stimulation intervention can alleviate the effects of immobilization on motor learning and fine motor skills.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Quadruple blind (participant, care provider, investigator, outcomes assessor)
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| Immobilization and Transcranial Direct Current Stimulation | Experimental | Device: sham transcranial direct current stimulation, Procedure: immobilizationThe participants' right hands will be immobilized for 16 hours, and they will receive 20 minutes of transcranial direct current stimulation before the immobilization period ends. |
| Immobilization and Sham Transcranial Direct Current Stimulation | Experimental | Procedure: transcranial direct current stimulation, Procedure: immobilizationThe participants' right hands will be immobilized for 16 hours, and they will receive 20 minutes of transcranial direct current stimulation before the immobilization period ends. |
| Blank control group | No intervention | – |
Who may qualify
- Ages
- 18 to 25 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (3 listed)
- (1) age between 18 and 25 years;
- (2) normal or corrected-to-normal vision;
- (3) right-handedness.
Key exclusion criteria (3 listed)
- (1) with history of pregnancy, cardiovascular disease, other physical impairments or illnesses;
- (2) with personal or family history of mental illness;
- (3) implanting any internal or external medical devices;
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| transcranial direct current stimulationThe intervention will be conducted using a battery-powered stimulator (TCS-E2000, Shenzhen Yingchi Technology Co., Ltd) through a pair of saline-soaked sponge electrodes (5 cm × 5 cm).The stimulation intensity will be set at 2 mA. The stimulation will last for 20 minutes, with a 10 s fade-in period at the start and a 10-s fade-out period at the end of stimulation. The anodal electrode will be placed over the primary motor cortex (M1), and the reference electrode will be positioned at the center of the forehead. | Procedure or surgery | Immobilization and Sham Transcranial Direct Current Stimulation |
| sham transcranial direct current stimulationThe intervention will be conducted using a battery-powered stimulator (TCS-E2000, Shenzhen Yingchi Technology Co., Ltd) through a pair of saline-soaked sponge electrodes (5 cm × 5 cm).The stimulation intensity will be set at 2 mA. The anodal electrode will be placed over the primary motor cortex (M1), and the reference electrode will be positioned at the center of the forehead for 20 minutes. However, there will be current only during the first 10 seconds and the last 10 seconds. | Device | Immobilization and Transcranial Direct Current Stimulation |
| immobilizationThe researchers will use an upper limb fixation splint to fix the right upper limb of the participants, with the elbow joint flexed at 90 degrees, to ensure that all movements of the wrist, metacarpophalangeal joints, proximal interphalangeal joints, and interphalangeal joints are completely restricted. To avoid discomfort caused by the splint, soft bandages will be wrapped around the hand, and the splint will be adjusted to fit the shape of the hand. Ensure that the fingertips are visible to ensure good blood circulation. The subjects need to wear the upper limb fixation splint for 16 hours. Instruct the subjects to minimize movement and use of the right upper limb as much as possible. During the immobilization process, pay attention to checking if the participants have numbness or other discomfort, as well as whether the blood flow is good. If any adverse symptoms occur, the immobilization will be immediately terminated. | Procedure or surgery | Immobilization and Sham Transcranial Direct Current Stimulation, Immobilization and Transcranial Direct Current Stimulation |
Primary outcome
Sequence Reaction Time Task
Time frame: Baseline; after one week
The participants will sit in front of the laptop and placed their four right fingers on the four keys on the keyboard. In this task, a white circle appears above one of four horizontally arranged white squares on the computer screen with black background. Participans will be instructed to press the proper button on the response pad (buttons H, J, K, L) using the corresponding finger of the right hand (index finger for button H, middle finger for button J, ring finger for button K, and small finger for button L) when the white circle appeared at the left side, middle-left side, middle-right side, or right side of the computer screen, respectively. Each session consists of eight blocks, with each block comprising 120 trials.
2 secondary outcomes
Purdue Pegboard Test
Time frame: Baseline; after one week
Reach and grasp action test
Time frame: Baseline; after one week
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 30 Jul 2025.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
The record lists no contact. Use the official record to reach the sponsor.
Questions about this trial
What is this clinical trial studying?
A study testing transcranial direct current stimulation and immobilization in people with Transcranial Direct Current Stimulation, run by Beijing Sport University.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 30 Jul 2025. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Sequence Reaction Time Task (time frame: Baseline; after one week). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 30 Jul 2025.