Clinical trials: Immune Health
HIV Infections
Reducing HIV Risks in African American Teens
This study is developing and testing an innovative, parent education intervention, Preparing Our Sons and Daughters for Healthy Futures.
- Trial name
- NCT00963963
- Testing
- Healthy Futures parent education
- Where
- United States
- Volunteers
- 1,200 people
- Sponsor
- Education Development Center, Inc.
Hiv, Contraception
Mobile Phone Messaging to Improve Reproductive Health for Women Living With HIV in Kenya (Mobile WACh Empower)
Use of a mobile health (mHealth) intervention to provide reproductive life counseling to women living with HIV may improve delivery of integrated reproductive health/HIV services and prevent adverse reproductive health outcomes.
- Conditions
- Hiv, Contraception, Fertility Issues
- Trial name
- NCT05285670
- Testing
- Digital counseling plus interactive two-way SMS dialogue
- Where
- 10 sites in Kenya
- Volunteers
- 3,310 people, healthy volunteers welcome
- Sponsor
- University of Washington
Asthma
A Trial Monitoring Therapy Pathways of Asthma Patients Treated With an Extrafine ICS/LABA/LAMA Single-inhaler Triple Therapy in a Real-world Setting and Characterizing the Effects on Health-related Out-comes
TriMaximize, a non-interventional trial aims to collect prospective, longitudinal data from asthma patients under routine care, for whom their treating physician has decided to prescribe Trimbow®…
- Trial name
- TriMaximize (NCT04902573)
- Testing
- Non-interventional
- Where
- United Kingdom
- Volunteers
- 147 people
- Sponsor
- Chiesi UK
URTI - Viral Upper Respiratory Tract Infection
A Study to Assess the Effect Probiotic Supplement on Immune Health in Teachers Prone to Upper Respiratory Tract Infection
The present study is a randomized, placebo-controlled, double-blind, parallel-group clinical studydesigned to assess the effects of IP on immune health in teachers prone to URTI.
- Trial name
- NCT07033754
- Testing
- Propionibacterium freudenreichii P.UF1, Microcrystalline cellulose, calciumcarbonate, Mg Stearate, Sylysia
- Where
- 6 sites in India
- Volunteers
- 100 people
- Sponsor
- Vedic Lifesciences Pvt. Ltd.
Type 1 Diabetes
School Partnered Collaborative Care (SPACE) Intervention for Children With Type 1 Diabetes
This is a pilot trial of a school-partnered collaborative care (SPACE) model for pediatric type 1 diabetes. The trial will investigate the feasibility and acceptability of SPACE for children with type 1 diabetes in the school…
- Trial name
- SPACE (NCT06420661)
- Testing
- SPACE for T1D, Enhanced usual care
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Pittsburgh
Asthma, Allergy
Urban Environmental Factors and Childhood Asthma
Minority children who grow up in poor urban neighborhoods have the highest rates of asthma, and also experience greater morbidity from acute exacerbations of this disease.
- Trial name
- URECA (NCT00114881)
- Where
- 4 sites in United States
- Volunteers
- 560 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
IPV, HIV
Tu'Washindi RCT: Adolescent Girls in Kenya Taking Control of Their Health
This study will test the effectiveness of a youth-designed multilevel intervention, Tu'Washindi, to increase PrEP use and reduce intimate partner violence (IPV) among Kenyan AGYW and to identify implementation challenges and…
- Conditions
- IPV, HIV, PrEP
- Trial name
- NCT05599581
- Testing
- Tu'Washindi
- Where
- 2 sites in Kenya
- Volunteers
- 1,562 people, healthy volunteers welcome
- Sponsor
- RTI International
COPD, Asthma
Health Effects of Secondhand Smoke Exposure in Outdoor Smoking Areas in Patients With COPD and Asthma ( TackSHSWP5 )
Within the TackSHS project (H2020 project grant agreement No 681040), we will conduct a clinical research study, aiming at: i) to measure respiratory health effects when exposed to secondhand smoke (SHS) in patients with asthma…
- Conditions
- COPD, Asthma, Second Hand Tobacco Smoke
- Trial name
- TackSHSWP5 (NCT03074734)
- Testing
- Exposure to secondhand tobacco smoke
- Volunteers
- 60 people
- Sponsor
- Institut Català d'Oncologia
Arthritis, Rheumatoid, Medication Adherence
Wireless Motion Sensors for Rheumatoid Arthritis Patients - Pilot Study
This study aims to provide preliminary evidence of the validity of a sensor-based assessment of rheumatoid arthritis (RA) symptoms, and to collect structured qualitative feedback from RA Enbrel patients regarding the potential of…
- Trial name
- NCT02296632
- Testing
- Motion sensors and daily online assessments
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Cedars-Sinai Medical Center
HIV Infections
PrEP2Prevent An Online PrEP Navigation and Activation Intervention
The goal of this clinical trial entitled, PrEP2Prevent: An Online PrEP Navigation and Activation Intervention for YMSM, is to develop and test a method for supporting access to an HIV prevention medication called Pre-Exposure…
- Trial name
- P2P (NCT05281393)
- Testing
- PrEPresent
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Los Angeles
Hiv
Tele-Coaching Community-Based Exercise (CBE) Study
The primary aim of this research is to evaluate the implementation of an online tele-coaching community-based exercise (CBE) intervention with adults living with HIV.
- Trial name
- NCT05006391
- Testing
- Tele-Coaching (Online) Community-Based Exercise
- Where
- Canada
- Volunteers
- 33 people
- Sponsor
- University of Toronto
Bronchial Asthma, Adherence, Medication
Cognitive and Emotional Factors Relation to Treatment Adherence in Asthmatic Patients in Upper Egypt
Non-adherence to controller therapy is one of the main reasons of poor asthma control. Adherence to medication in different studies range between 30 and 70% .
- Trial name
- NCT06200623
- Volunteers
- 138 people
- Sponsor
- Entsar Hsanen
Suicide, Suicidal Ideation
Telehealth to Reduce Suicidality and Improve HIV Care Engagement in Tanzania
The overall objectives of the proposed research are to develop a brief telehealth counseling intervention to provide support for people living with HIV and experiencing suicidal ideation, and to support HIV care engagement.
- Conditions
- Suicide, Suicidal Ideation, HIV Infections, Adherence, Medication
- Trial name
- NCT04696861
- Testing
- IDEAS for Hope, Enhanced Standard of Care (Safety Planning)
- Where
- 2 sites in Tanzania
- Volunteers
- 60 people
- Sponsor
- Duke University
Multiple Sclerosis (MS)
Next-Gen MS: Feed-forward PRO Data for MS Research
This Next Generation learning health system for Multiple Sclerosis (Next-Gen MS) study is a sub-study of the MS-LINK™ Outcomes Study (NCT04735406).
- Trial name
- NCT04907305
- Where
- 8 sites in United States
- Volunteers
- 1,594 people
- Sponsor
- EMD Serono Research & Development Institute, Inc.
HIV Infections
Improving Health Outcomes in Young Cisgender Men and Transgender Women (mLab App)
The mLab App combines HIV prevention information with push notifications/reminders to complete HIV testing and an automated image processing feature to provide real-time feedback on home-based HIV test results.
- Trial name
- NCT03803683
- Testing
- mLab App, HIV Prevention Information, HIV Home Tests
- Where
- 2 sites in United States
- Volunteers
- 525 people, healthy volunteers welcome
- Sponsor
- Rebecca Schnall, RN, MPH, PhD
HIV Infections, Adolescent Behavior
Improving Care and Community Representation for Adolescents and Young Adults Living With HIV in West Africa
Context: HIV-positive young people aged 15 to 24 are a heterogeneous population in terms of gender, age, mode of transmission, sexual orientation and risk-taking.
- Conditions
- HIV Infections, Adolescent Behavior, Transition
- Trial name
- TRANSITIONS (NCT05405322)
- Where
- 4 sites in Burkina Faso, Senegal
- Volunteers
- 267 people
- Sponsor
- Institut de Recherche pour le Developpement
Skin Cancer, Melanoma
Nurses' Health Study and Health Professionals Follow-Up Study (Dermatological Component)
To determine the relationships of dietary factors with the subsequent risk of dermatological diseases (such as skin cancers and inflammatory or autoimmune dermatoses) in a cohort of female registered nurses and male health…
- Conditions
- Skin Cancer, Melanoma, Non-melanoma Skin Cancer, Psoriasis
- Trial name
- NCT03253666
- Testing
- Nutrient Intake
- Volunteers
- 173,229 people
- Sponsor
- Harvard School of Public Health (HSPH)
All
Project Baseline Health Study
This study is the first initiative of Project Baseline, a broader effort designed to develop a well-defined reference, or "baseline," of good health as well as a rich data platform that may be used to better understand the…
- Trial name
- NCT03154346
- Where
- 5 sites in United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Baseline Study LLC
Sleep, Fatigue
Sleep Hygiene and Relaxation Intervention to Improve Sleep and Fatigue for Children Receiving Maintenance Chemotherapy
This pilot randomized controlled trial examined the feasibility, acceptability and effectiveness of an intervention to improve sleep quality and decrease fatigue levels in children with a diagnosis of ALL, during maintenance…
- Conditions
- Sleep, Fatigue, Acute Lymphoblastic Leukemia
- Trial name
- SHARI (NCT02295839)
- Testing
- Sleep Hygiene and Relaxation Education
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- The Hospital for Sick Children
Rheumatoid Arthritis
A Multi-Center Clinical Trial to Determine the Impact of a Mobile Health Application on Rheumatoid Arthritis Shared Decision Making
The overall goal is to improve shared decision-making (SDM) about treatment options and thereby enhance disease outcomes and health-related quality of life (HRQOL) for patients with rheumatoid arthritis (RA).
- Trial name
- NCT03773471
- Testing
- Mobile Health App
- Where
- 2 sites in United States
- Volunteers
- 69 people
- Sponsor
- Mayo Clinic
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