Clinical trials: Immune Health
HIV Infections
Effects of Two Anti-HIV Drug Regimens on Quality of Life and Health Care Use Among SMART Study Participants
The purpose of this study is to compare the effects of two different anti-HIV drug regimens on quality of life and health care utilization among SMART study participants.
- Trial name
- NCT00385632
- Testing
- Antiretroviral Regimens
- Where
- 67 sites in United States
- Volunteers
- 1,224 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Neuromyelitis Optica Spectrum Disorder
CorEvitas SPHERES (Synergy of Prospective Health & Experimental Research for Emerging Solutions) Registry for Neuromyelitis Optica Spectrum Disorder (NMOSD)
This is a Prospective, observational research study for patients with NMOSD under the care of a licensed neurologist. Approximately 800 patients and 35 clinical sites in North America will be recruited to participate with no…
- Trial name
- NCT04886492
- Where
- United States
- Volunteers
- 800 people
- Sponsor
- CorEvitas
Rheumatoid Arthritis
RHEUPP - A Rheumatological Follow-up Management App
The purpose of this Non-inferiority Randomized Clinical Trial is to evaluate the effectiveness of RHEUPP App during telehealth follow-up in a population of Rheumatoid Arthritis patients from a Tertiary Rheumatology Service in…
- Trial name
- RHEUPP (NCT06217172)
- Testing
- RHEUPP App, Usual Follow-up
- Volunteers
- 88 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
HIV/AIDS
Changing Health Through Food Support (CHEFS) Program
UCSF and Project Open Hand (POH), a community based organization in San Francisco which provides meals and groceries to chronically ill clients in the Bay Area, have partnered to conduct an initial randomized controlled trial…
- Trial name
- CHEFS (NCT03191253)
- Testing
- Medically-appropriate meals and groceries
- Volunteers
- 191 people
- Sponsor
- University of California, San Francisco
Gut Microbiota, Gastrointestinal Symptoms
Mother-Infant Cohort Study in Malaysia and China
This mother-infant cohort study aims to determine the geographic differences in the microbial profiles in breast milk from mothers living in Malaysia and China that are potentially important determinants of infant development.
- Conditions
- Gut Microbiota, Gastrointestinal Symptoms, Temperament, Eczema
- Trial name
- NCT04919265
- Testing
- No intervention - mother-infant cohort study
- Where
- Malaysia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Substance Dependence, HIV (Human Immunodeficiency Virus)
Pre-exposure Prophylaxis (PrEP) for Health
This randomized controlled trial will test the efficacy of "PrEP for Health," a behavioral intervention to improve the use of antiretroviral pre-exposure prophylaxis (PrEP) among at-risk people who inject drugs (PWID) in two…
- Trial name
- PrEP (NCT04430257)
- Testing
- HIV and PrEP education, Motivational interviewing, Problem-solving and planning
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- Brown University
Allergy
Study of Indoor Air Pollutants and Their Impact in Children's Health and Wellbeing
The goal of this study is to identify and assess in real time the impact of the combined action of various types of air and dust pollutants within a classroom on children's health and quality of life, particularly regarding…
- Trial name
- SynAir-G2 (NCT07402200)
- Testing
- Standardized questionnaires, Lung function tests, Prick tests
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Montpellier
Autoimmune Disease
Gastrointestinal and Health-related Quality of Life Outcomes in Patients With Autoimmune Diseases Treated With Mycophenolate
Treatment with the immunosuppressive drug mycophenolate mofetil (MMF) may result in gastrointestinal (GI) complications in some patients.
- Trial name
- NCT00351377
- Testing
- Enteric-coated Mycophenolate Sodium
- Where
- Germany
- Volunteers
- 111 people
- Sponsor
- Novartis Pharmaceuticals
COVID-19, Long COVID
Using Data From a Multisensor Rapid Health Assessment Device to Predict Decompensation in Long COVID (AIDI)
We are conducting a research study at the VA hospital in Bedford, MA to learn more about how a multisensor rapid health assessment device, MouthLab, can help predict or anticipate future health complications in patients with…
- Trial name
- AIDI (NCT05713266)
- Testing
- MouthLabTM
- Where
- United States
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Edith Nourse Rogers Memorial Veterans Hospital
HIV/AIDS and Infections, Drug Abuse
Preventing HIV/STI in Urban Adolescents Via an mHealth Primary Care Intervention
The study evaluates the preliminary efficacy of an innovative mobile-health (mHealth) intervention (hereon referred to as S4E) to improve human immunodeficiency virus and sexually transmitted infection testing and reduce HIV/STI…
- Conditions
- HIV/AIDS and Infections, Drug Abuse, Adolescent Behavior, Drug Usage
- Trial name
- NCT03368456
- Testing
- S4E, Usual Care
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Michigan
HIV, AIDS
Motivating HIV+ Women: Risk Reduction and ART Adherence
The purpose of this study is to determine if a group motivational interviewing based intervention will increase adherence to antiretroviral medications and use of risk reduction behaviors.
- Trial name
- KHARMA (NCT00253045)
- Testing
- Motivational groups
- Where
- United States
- Volunteers
- 207 people
- Sponsor
- Emory University
Hiv, Alcohol Problem
Telemedicine for Unhealthy Alcohol Use in Persons Living With HIV Using CETA
This study is designed to examine the efficacy of an alcohol-focused brief intervention alone versus the brief intervention plus referral to a transdiagnostic cognitive-behavioral intervention to address unhealthy alcohol use and…
- Trial name
- TALC (NCT04955795)
- Testing
- Alcohol Brief Intervention (BI), Common Elements Treatment Approach (CETA) via Telemedicine
- Where
- United States
- Volunteers
- 308 people
- Sponsor
- University of Alabama at Birmingham
Diabetes Type 1, Diabetes Type 2 on Insulin
Performance and Safety Evaluation of the EkiYou V2 Application in Patients With Diabetes Using Multiple Daily Insulin Injections (EkiYou-Study1)
EkiYou-Study-1 is an interventional before/after clinical investigation according to EU 2017/745. It is conducted in 21 adults with diabetes and treated by multiple daily insulin injections.
- Conditions
- Diabetes Type 1, Diabetes Type 2 on Insulin, Pancreatogenous Diabetes
- Trial name
- NCT06529705
- Testing
- EkiYou V2
- Where
- France
- Volunteers
- 21 people
- Sponsor
- University Hospital, Montpellier
Multiple Sclerosis (MS)
MS PATHS COVID-19 Questionnaire Data Linkage Sub-Study
The primary objective of this sub-study is to supplement the Multiple Sclerosis Partners Advancing Technology and Health Solutions (MS PATHS) dataset with coronavirus disease 2019 (COVID-19)-related health information obtained…
- Trial name
- NCT05058729
- Where
- 6 sites in United States
- Volunteers
- 1,507 people
- Sponsor
- Biogen
Obesity, Growth
Essential Fatty Acids During Complementary Feeding
The objective of this intervention study is to examine the effect of n-3 LCPUFA on growth and body composition, intestinal health and microbiotic composition, immune function and risk markers for later diseases in 9-18 months old…
- Conditions
- Obesity, Growth, Metabolic Syndrome, Cardiovascular Disease
- Trial name
- EFiON (NCT00631046)
- Testing
- Fish Oil, Sunflower Oil
- Where
- Denmark
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Diabetes Mellitus, Arthritis, Rheumatoid
Psychosocial Treatment Intervention in Persons Newly Diagnosed With Rheumatoid Arthritis or Diabetes
The aim of this study is to evaluate the results of psychosocial treatment in patients with newly diagnosed rheumatoid arthritis and/or diabetes.
- Conditions
- Diabetes Mellitus, Arthritis, Rheumatoid, Coping Skills
- Trial name
- NCT01066130
- Testing
- Intensive individualized psychosocial treatment, Minimal treatment arm
- Where
- 2 sites in Sweden
- Volunteers
- 200 people
- Sponsor
- Karolinska Institutet
Myasthenia Gravis
Physical Activity Monitoring in Myasthenia Gravis
The goal of this observational study is to evaluate the feasibility of using wearable sensor and digital technologies to measure motor and speech function in adults with autoimmune Myasthenia Gravis (MG).
- Trial name
- NCT06277830
- Testing
- Wearable sensor
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Massachusetts General Hospital
Asthma in Children
Oral Health Status of Asthmatic Children
This study aimed to investigate the dental caries experience, periodontal health and salivary properties of asthmatic and non-asthmatic children ⁄ adolescents.
- Trial name
- NCT04388098
- Testing
- Diagnosis of caries experience and periodontal health
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Trakya University
Hepatitis C, Chronic, HIV Infection
ADHEPTA Study: Adherence Questionnaire in Hepatitis C
Main objective: To study and validate a questionnaire measuring treatment adherence in patients with Hepatitis C virus (HCV) infection.
- Trial name
- ADHEPTA (NCT00998621)
- Testing
- Adherence questionnaire
- Where
- Spain
- Volunteers
- 1,120 people
- Sponsor
- Fundacion IMIM
COPD, Asthma
Participatory Action Research to Evaluate the Delivery of the MISSION ABC Service Model and Assess Health Service and Clinical Outcomes
Innovations aimed at improving new patient identification, diagnosis, nonpharmacological treatment, supported self-management, and remote monitoring, together with new methods of clinical support could improve outcomes in…
- Conditions
- COPD, Asthma, Breathlessness
- Trial name
- NCT03096509
- Testing
- MISSION ABC Integrated Care clinic
- Where
- United Kingdom
- Volunteers
- 342 people
- Sponsor
- Portsmouth Hospitals NHS Trust
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