Clinical trials: Immune Health
Preterm Birth, Pediatric Cancer
eHealth as an Aid for Facilitating and Supporting Self-management in Families With Long-term Childhood Illness
The overall aim is twofold: 1) to stretch the borderline regarding the present knowledge of clinical and economic cost-effectiveness of eHealth as an aid for facilitating and supporting self-management in families with long-term…
- Conditions
- Preterm Birth, Pediatric Cancer, Hirschsprung Disease, Congenital Malformation
- Trial name
- eChildHealth (NCT04150120)
- Testing
- e-health device with application, Mobile phone text messaging, early detection of cerebral palsy using a mobile phone application
- Where
- 7 sites in Denmark, Ethiopia and 1 more
- Volunteers
- 720 people
- Sponsor
- Lund University
Diabetes Mellitus, Type 1
Early Feasibility Study of Zone-MPC and HMS With DiAs in the Outpatient Setting
This is a feasibility study of an artificial pancreas (AP) system with our previously validated Zone-MPC and Health Monitoring System (HMS) algorithms (ClinicalTraisl.gov: NCT01929798) integrated into the Diabetes Assistant…
- Trial name
- NCT02463682
- Testing
- CGM and Insulin Pump, Closed-Loop Control System
- Where
- 3 sites in United States
- Volunteers
- 9 people
- Sponsor
- Sansum Diabetes Research Institute
Asthma (Diagnosis)
Optimizing a Sensor-Enabled mHealth Intervention for Adolescents With Suboptimal Asthma Control
Asthma affects nearly 1 in 10 teenagers in the United States and can seriously impact their health and daily life. Teens are expected to manage their asthma by taking medications correctly and paying attention to symptoms, but…
- Trial name
- NCT07301060
- Testing
- Sensor-Enabled mHealth Intervention for Adolescents with Suboptimal Asthma Control, mHealth standard of care control condition
- Where
- 2 sites in United States
- Volunteers
- 160 people
- Sponsor
- University of Kansas
HIV Infections, HIV Prevention and Care
HealthMpowerment Korea: Pilot Testing the Cultural Adaptation of a Digital HIV Intervention for Men Who Have Sex With Men in South Korea
This study tests a mobile application (app) designed to support sexual health and prevent human immunodeficiency virus (HIV) among young men in South Korea.
- Conditions
- HIV Infections, HIV Prevention and Care, Risk Reduction Behavior, Digital Health
- Trial name
- HMP Korea (NCT07741123)
- Testing
- Bandi Mobile Application (Full Access), Information-Only Mobile Application (Limited Access)
- Where
- South Korea
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Seul Ki Choi
Myasthenia Gravis (MG), Myasthenia Gravis, Generalized
AXIS MG Patient Registry
The goal of the AXIS Autoimmune Neurology Registry is to learn about the experiences of adults living with autoimmune neurological disorders, starting with myasthenia gravis (MG), over time.
- Conditions
- Myasthenia Gravis (MG), Myasthenia Gravis, Generalized, Myasthenia Gravis, Ocular, Myasthenia Gravis Crisis
- Trial name
- AXIS (NCT07761026)
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Autoimmune Neurology Alliance
Type 1 Diabetes, Osteoporosis
Bone Health in Youth With Type 1 Diabetes
This is an observational study of children and young adults ages 6-20 years with type 1 diabetes and age- and race-matched controls.
- Trial name
- NCT02140424
- Where
- United States
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Immune Function, Immunity
Effects of TM02® Supplementation on Immune Function in Children
This randomized, double-blind, placebo-controlled clinical study evaluated the effects of 12 weeks of TM02® supplementation on immune-related outcomes in generally healthy children aged 2 to 12 years.
- Trial name
- NCT07853573
- Testing
- TM02®
- Where
- Malaysia
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Ligno Biotech Sdn. Bhd.
JIA, Self-Evaluation
Using Self-evaluation to Increase Visit Intervals in Juvenile Idiopathic Arthritis
In the THUIS study, JIA patients in clinical remission will skip one 3-monthly hospital control visit and instead monitor their disease activity at home. Outcomes at 6 months will be compared to those from a historical cohort.
- Trial name
- THUIS (NCT05603286)
- Testing
- Home-monitoring
- Where
- Netherlands
- Volunteers
- 85 people
- Sponsor
- Joeri van Straalen
Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
AI-Predicted Disease Trajectories in Diabetes: A Retrospective Study
The study explores the utilization of artificial intelligence (AI) to predict disease progression trajectories in patients with diabetes.
- Trial name
- AI-TRYDIA (NCT06280729)
- Testing
- AI-Analyis
- Where
- Italy
- Volunteers
- 10,000 people
- Sponsor
- IRCCS San Raffaele
HIV Infections
Outcome Evaluation of Minority AIDS Initiative Programs in the New York EMA
This outcome evaluation effort provides the opportunity to learn what programmatic approaches effectively address two of the most difficult hurdles in HIV health services delivery: (1) getting people who would benefit from health…
- Trial name
- NCT00273403
- Testing
- Maintenance in Care Services, Access to Care Services
- Where
- 23 sites in United States
- Volunteers
- 5,100 people
- Sponsor
- The New York Academy of Medicine
Asthma
Better Pediatric Asthma Outcomes Through Chronic Care
This 3-year, multi-site study focuses on the translation of cost-effective methods to bring a chronic care model to the care of poor, minority, inner-city children with asthma, at risk of the worst outcomes for the leading…
- Trial name
- NCT00355069
- Testing
- electronic (computer based) provider feedback tool
- Where
- United States
- Volunteers
- 548 people
- Sponsor
- UConn Health
HIV Infections
Evaluation of an HIV Outreach Program
This study evaluates outreach to HIV-infected people living in unstable housing in New York City who are new to CitiWide Harm Reduction.
- Trial name
- NCT00300183
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Montefiore Medical Center
General Health and Wellness, Energy and Vitality
M4C Nutraceutical Intervention Human Health Effects Pilot
This 3 month pilot study will be an unblinded, convenience sampling, nutraceutical intervention trial. Twenty fasted subjects will undergo a baseline health assessment via a questionnaire, baseline clinical chemistries, blood…
- Conditions
- General Health and Wellness, Energy and Vitality, Cognitive Function and Mental Health, Weight Management
- Trial name
- M4C Pilot (NCT06476236)
- Testing
- M4C
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Concordia University Wisconsin
Relapsing Remitting Multiple Sclerosis (RRMS)
Disease Control and Safety in Patients With Relapsing Remitting Multiple Sclerosis (RRMS) Switching From Natalizumab to Fingolimod
This study evaluated disease control during different lengths of treatment transition from natalizumab to fingolimod.
- Trial name
- TOFIINGO (NCT01499667)
- Testing
- Fingolimod
- Where
- 44 sites in Australia, Austria and 9 more
- Volunteers
- 142 people
- Sponsor
- Novartis Pharmaceuticals
HIV Infections
Stigma, Social Support and Quality of Life
The primary goal of this observational study is to investigate the relationship between perceived stigma and social support in HIV+ patients.
- Trial name
- 4826 (NCT05781204)
- Testing
- Survey
- Where
- Italy
- Volunteers
- 96 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Asthma
Electronic Health Record (EHR) Decision Support to Improve Outpatient Asthma Care
To determine whether an innovative clinical decision support system embedded in an existing electronic health record (EHR) will improve provider adherence to the existing National Asthma Education and Prevention Program (NAEPP)…
- Trial name
- NCT00918944
- Testing
- Control, Intervention
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Children's Hospital of Philadelphia
Diet Intervention
Effects of Almonds on Immune Health and Responsiveness
This study has the primary objective of investigating the benefits of consuming whole almonds on immune health and immune response in adults with obesity.
- Trial name
- NCT05530499
- Testing
- Almond supplementation, Cookie supplementation
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
HIV Infections
AmbassADDOrs for Health Study
The goal of the study is to evaluate Malkia Klabu ("Queen Club") in Tanzania, a loyalty program intervention that creates adolescent girls and young women (AGYW)-friendly drug shops where AGYW can access HIV prevention services…
- Trial name
- ADDO (NCT05357144)
- Testing
- Loyalty card program at drug shops & supply of HIVST and SRH products, Comparison drug shops
- Where
- 2 sites in Tanzania
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Human Immunodeficiency Virus
Supporting Adolescents to Adhere - an Intervention Using Airtime Rewards Allocated by a Prize Drawing
This study is an extension of Reminding Adolescents to Adhere (RATA) (Unique protocol ID: 1R01HD074925-01). Participants for SATA will be recruited during the RATA month 24 exit survey.
- Trial name
- SATA (NCT02918838)
- Testing
- Own Adherence Group, Fixed Adherence Group, Control Group
- Where
- Uganda
- Volunteers
- 216 people
- Sponsor
- RAND
Diabetes Mellitus, Type 1, Type1diabetes
Group Education Trial to Improve Transition in Type 1 Diabetes
The investigators will conduct a randomized controlled trial (RCT) to examine group education visits as an innovative and potentially cost-effective approach to transition care delivery, that can be easily integrated into usual…
- Conditions
- Diabetes Mellitus, Type 1, Type1diabetes, Insulin Dependent Diabetes
- Trial name
- GET-IT-T1D (NCT03703440)
- Testing
- Active arm, Control arm
- Where
- 2 sites in Canada
- Volunteers
- 212 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
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