Clinical trials: Immune Health
Multiple Sclerosis
Development and Evaluation of the Self-management Module in Patients With Multiple Sclerosis
Compared with other chronic disease states, MS patients feel more uncertainty and less control over illness and non-illness aspects of life, and as a result, they have poor self-management abilities.
- Trial name
- NCT05209113
- Testing
- Education
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Hacettepe University
Hiv, Medication Adherence
Development of a Silica Microparticle Taggant System to Measure ART Adherence
Developing technologies to help measure and provide tools to support medication-taking behaviors (medication adherence) is an important step to ending the human immunodeficiency virus (HIV) epidemic.
- Conditions
- Hiv, Medication Adherence, Compliance, Medication
- Trial name
- TruTag (NCT06465862)
- Testing
- TruTag System, Biktarvy Pill
- Sponsor
- Brigham and Women's Hospital
Pulmonary Disease, Chronic Obstructive
Sensor and Electronic Health Records (EHR) Integration Pilot Study
This is a pilot study that will evaluate the feasibility of collecting increasing amounts of clinical study data from subjects through sensor and web/app based methods and integrating it with data from their EHR to facilitate…
- Trial name
- NCT03357341
- Testing
- Mobile spirometer, Device sensor, Salbutamol
- Where
- United States
- Volunteers
- 194 people
- Sponsor
- GlaxoSmithKline
Asthma
Better Pediatric Asthma Outcomes Through Chronic Care
This 3-year, multi-site study focuses on the translation of cost-effective methods to bring a chronic care model to the care of poor, minority, inner-city children with asthma, at risk of the worst outcomes for the leading…
- Trial name
- NCT00355069
- Testing
- electronic (computer based) provider feedback tool
- Where
- United States
- Volunteers
- 548 people
- Sponsor
- UConn Health
Lymphoma
EFFECT OF A 16-SESSION QIGONG PROGRAM ON PHYSICAL AND MENTAL HEALTH IN PATIENTS WITH LYMPHOMA: A RANDOMIZED CONTROLLED TRIAL
The aim of the present study was to investigate in lymphoma patients the effects of a 16-session qigong programme (2 times a week) on physical and psychological parameters.
- Trial name
- NCT04701554
- Testing
- Qigong program, Information on healthy lifestyles, physical exercise and dietary recommendations.
- Where
- Spain
- Volunteers
- 39 people
- Sponsor
- Consuelo Lourdes Díaz Rodríguez
Asthma, Pulmonary Disease, Chronic Obstructive
Teaching Inhaler Use With the INCA Device in a Community Pharmacy Setting
The purpose of this trial is to discover whether providing feedback to patients from a device that records when and how well a patient uses a Seretide Diskus inhaler will lead to: Improved compliance with prescribed inhaler use…
- Trial name
- NCT02203266
- Testing
- Feedback, Education
- Where
- Ireland
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Beaumont Hospital
Type 1 Diabetes
Artificial Pancreas Technology to Reduce Glycemic Variability and Improve Cardiovascular Health in Type 1 Diabetes
This study will examine the potential cardiovascular effect(s) of artificial pancreas (AP) technology in patients with type 1 diabetes.
- Trial name
- WBH002 (NCT05653518)
- Testing
- Tandem t:slim X2 with Control-IQ Technology, Sensor augmented pump (SAP) therapy
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Virginia
HIV Infections, Sexually Transmitted Infection
PrEPwise Pilot Among Black Women in Eastern Virginia
HIV is a virus that affects many people, but Black women in the U.S. are a population at a much higher risk of getting it compared to white women-about 18 times higher.
- Trial name
- PrEPwise (NCT07398482)
- Testing
- PrEPwise, Usual care
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- Boston University
HIV Infections
PASEO Intervention for Adolescents Transitioning to Adult HIV Care in Urban Peru
This study is an evaluation of an intervention (nicknamed "PASEO") that aims to facilitate the transition to adult HIV care for adolescents living with HIV in Lima, Peru.
- Trial name
- PASEO (NCT05938803)
- Testing
- PASEO
- Where
- 4 sites in Peru
- Volunteers
- 160 people
- Sponsor
- Harvard University Faculty of Medicine
Graft Versus Host Disease, Hematopoietic and Lymphatic System Neoplasm
Evaluating the Effects of Propionate and Butyrate Supplementation on the Intestinal Health of Healthy Volunteers
This clinical trial evaluates how propionate and butyrate supplementation alters intestinal health in healthy volunteers and whether it would be feasible to administer these supplements to patients undergoing allogeneic…
- Conditions
- Graft Versus Host Disease, Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm
- Trial name
- NCT07611370
- Testing
- Biospecimen Collection, Microencapsulated Sodium Butyrate, Microencapsulated Sodium Propionate
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Cholera, Typhoid
Studies of Immune Responses to Orally Administered Vaccines in Developing Country
The efficacy and immunogenicity of enteric vaccines have generally been found to be lower in children in the developed than in the developing countries.
- Trial name
- NCT01019083
- Testing
- Control, Zinc Sulphate, Albendazole and Secnidazole
- Where
- Bangladesh
- Volunteers
- 1,016 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Psychological Well-being and Immune Health Profile
The Genomic and Well-Being Impacts of an Extraverted Behavior Intervention
8-week randomized intervention (with 3-month follow-up) that examines the impact of increased sociable behavior on emotional well-being and immune health profile
- Trial name
- NCT07690605
- Testing
- Sociable (extraverted) behavior
- Where
- United States
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- University of California, Riverside
Skin Cancer, Melanoma
Nurses' Health Study and Health Professionals Follow-Up Study (Dermatological Component)
To determine the relationships of dietary factors with the subsequent risk of dermatological diseases (such as skin cancers and inflammatory or autoimmune dermatoses) in a cohort of female registered nurses and male health…
- Conditions
- Skin Cancer, Melanoma, Non-melanoma Skin Cancer, Psoriasis
- Trial name
- NCT03253666
- Testing
- Nutrient Intake
- Volunteers
- 173,229 people
- Sponsor
- Harvard School of Public Health (HSPH)
Healthy Infants
HMOs on Infant Gut Microbiota Modulation and Development of the Immune System in Healthy Infants
The goal of this clinical trial is to learn how a mixture of human milk oligosaccharides impacts the development of the infant microbiota, the immune maturation and how the interaction between the microbiota and immune maturation…
- Trial name
- BELIEF (NCT06631937)
- Testing
- Human Milk Oligosaccharides
- Where
- 2 sites in Denmark
- Volunteers
- 334 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
HIV Infections, Smoking Cessation
BAPS in Botswana: The Thotloetso Trial
The main purpose of this research study is to compare traditional behavioral smoking cessation therapy with a different type of behavioral therapy-known as behavioral activation problem solving (BAPS)-for smoking cessation.
- Conditions
- HIV Infections, Smoking Cessation, Smoking
- Trial name
- BOTS (NCT04532970)
- Testing
- Cessation Counseling
- Where
- Botswana
- Volunteers
- 651 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Hypogonadism
Gonadal Dysfunction in Male Long-term Survivors of Malignant Lymphoma; Vitality
This study is a prospective non-randomised open label multicenter phase two study in male long-term survivors of malignant lymphoma including Hodgkin Lymphoma (HL) and Diffuse Large B-Cell Lymphoma (DLBCL).
- Trial name
- Vitality (NCT04492553)
- Testing
- AndroGel
- Where
- 3 sites in Denmark
- Volunteers
- 7 people
- Sponsor
- Lars Møller Pedersen
Cystic Fibrosis, Asthma
Measures of Respiratory Health (MRH)
The Lung Clearance Index, measured by multiple breath washout, is a measure of lung function that is considered a research tool in Canada as the device used to measure it is not approved by Health Canada.
- Conditions
- Cystic Fibrosis, Asthma, Sickle Cell Anemia, Bronchiolitis Obliterans
- Trial name
- MRH (NCT02657837)
- Where
- Canada
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Breast Neoplasm, Colorectal Neoplasm
Decision Aid Website in Helping to Make Decisions About Fertility in Participants With Cancer
This trial studies how well a decision aid website works in helping to make decisions about fertility in participants with cancer.
- Conditions
- Breast Neoplasm, Colorectal Neoplasm, Female Reproductive System Neoplasm, Health Care Provider
- Trial name
- NCT03141437
- Testing
- Best Practice, Educational Intervention, Internet-Based Intervention
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- M.D. Anderson Cancer Center
Human Immunodeficiency Virus
Medication Adherence in Human Immunodeficiency Virus (HIV)
Although effective treatments are currently available to treat human immunodeficiency virus (HIV), the retrovirus leading to acquired immune deficiency syndrome (AIDS), strict adherence to the treatment regimen is required.
- Trial name
- NCT02119390
- Testing
- Staff-delivered intervention sessions, Demographic Questionnaire, Questionnaires
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- St. Jude Children's Research Hospital
Type 1 Diabetes
School Partnered Collaborative Care (SPACE) Intervention for Children With Type 1 Diabetes
This is a pilot trial of a school-partnered collaborative care (SPACE) model for pediatric type 1 diabetes. The trial will investigate the feasibility and acceptability of SPACE for children with type 1 diabetes in the school…
- Trial name
- SPACE (NCT06420661)
- Testing
- SPACE for T1D, Enhanced usual care
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Pittsburgh
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