Clinical trials: Immune System Function
Multiple Sclerosis
The Effect of High Tone Power Therapy on Fatigue and Functional Outcomes in Multiple Sclerosis
To investigate the effect of "High Tone Power Therapy" (HTPT) on fatigue and functional outcomes in multiple sclerosis (MS). BACKGROUND: Fatigue and functional limitations considered serious disorders in patients with multiple…
- Trial name
- NCT04530669
- Testing
- High Tone Power Therapy, exercise program
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Lama Saad El-Din Mahmoud
Hematologic Disorder
Lenalidomide as Immune Adjuvant in Patient's With Chronic Lymphocytic Leukemia (CLL)
The goal of this clinical research study is to learn if lenalidomide can increase the level of immunoglobulins (parts of the blood that may help to improve the immune system's function) and/or will improve the protective effect…
- Trial name
- NCT01924169
- Testing
- Lenalidomide, Influenza Vaccine, Pneumovax Vaccine
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- M.D. Anderson Cancer Center
Type 1 Diabetes (T1D)
Effect of Melatonin Supplementation on Excecutive Functions, Sleep Quality and Glycemic Metrics Among Adolescents With Type 1 Diabetes Mellitus
Cognitive impairment, poor sleep quality, Alzheimer's disease and dementia are complications of uncontrolled type 1 diabetes (T1D).
- Trial name
- MS642/2024 (NCT07592442)
- Testing
- Melatonin tablet 3 mg once daily
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Ain Shams University
Multiple Sclerosis
The Effect of Dual Task On Upper Extremity Functions In Multiple Sclerosis Patients
The primary aim of this study was to investigate the effect of dual tasking on upper extremity functions in individuals with multiple sclerosis (MS) and compare with healthy controls.
- Trial name
- NCT06270342
- Testing
- dual task assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Type 1 Diabetes Mellitus
Effects of Vitamin C and E on Endothelial Function in Adolescent Diabetes
The endothelium is the lining of the blood vessels that helps prevent damage to the vessels. The endothelium does not function as well as it should in adolescents with type 1 diabetes. This causes future diabetes complications.
- Trial name
- NCT02019186
- Testing
- Vitamin C, Vitamin E
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Nationwide Children's Hospital
Multiple Sclerosis
The Effects of Different Medical Marijuana Strains on Motor and Cognitive Function in People With Multiple Sclerosis
Over the last two years, the United States has witnessed enormous change concerning the acceptance of marijuana. The number of persons with MS (PwMS) using cannabis to treat their symptoms is expected to rise, and it is important…
- Trial name
- NCT03172741
- Testing
- Medical Marijuana
- Sponsor
- Colorado State University
Type 1 Diabetes, Basal-bolus Multiple-dily Insulin Injections
Self-management of Type 1 Diabetes Under Functional Insulin Therapy
Therapeutic education of patients is a mandatory component of intensive insulin therapy of type 1 diabetes in order to reach optimal safety and efficacy.
- Conditions
- Type 1 Diabetes, Basal-bolus Multiple-dily Insulin Injections, Insulin Pump (CSII)
- Trial name
- EVAUTODIAB (NCT02272348)
- Testing
- Training course to functional insulin therapy, Usual diabetes management.
- Where
- France
- Volunteers
- 13 people
- Sponsor
- University Hospital, Montpellier
Mild Cognitive Impairment, Idiopathic Membranous Nephropathy
the Effects of Different Treatment Schemes on Cognitive Function of Patients With Idiopathic Membranous Nephropathy
This study intends to apply prospective, open, single-center, randomized controlled study to evaluate the cognitive status of patients with Idiopathic membranous nephropathy and the influence of different treatment schemes on the…
- Trial name
- NCT06245707
- Testing
- prednisone,methylprednisone and cyclophosphamide, Rituximab
- Where
- China
- Volunteers
- 2 people
- Sponsor
- Beijing Friendship Hospital
Lupus Erythematosus, Systemic
Effects of High-intensity Interval Training in Patients With Systemic Lupus Erythematosus
The aim of this study is to evaluate the safety and effects of high-intensity interval training (HIIT) combined with resistance training in patients with systemic lupus erythematosus
- Trial name
- SLE-HIIT (NCT06166199)
- Testing
- HIIT combined with resistance training
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Karolinska Institutet
Adherence, Medication, Functional Constipation
Adherence and Outcomes in Functional Constipation With a Constipation Action Plan
We will be assessing for improvement in reported symptoms as well as reported quality of life in pediatric patients with functional constipation using a constipation action plan and an adherence log.
- Conditions
- Adherence, Medication, Functional Constipation, Pediatric ALL, Survey, Family Life
- Trial name
- NCT04614935
- Testing
- Action Plan
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Rheumatoid Arthritis
Investigation of Upper Extremity Functions in Patients With Rheumatoid Arthritis
There are limited studies in the literature evaluating upper extremity functional exercise capacity, muscle functions and daily living activities in rheumatoid arthritis patients.
- Trial name
- NCT06767618
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Kirsehir Ahi Evran Universitesi
Multiple Sclerosis, Disabilities Multiple
The Relationship of Neuropathic Pain With Incontinence, Disability and Life Quality in Multiple Sclerosis Patients
The aim of this study to evaluate the relationship of neuropathic pain with urinary and bowel incontinence, functional disability and quality of life in patients with multiple sclerosis.
- Conditions
- Multiple Sclerosis, Disabilities Multiple, Quality of Life, Incontinence, Urinary
- Trial name
- NCT05374811
- Testing
- Neuropathic Pain
- Where
- Turkey (Türkiye)
- Volunteers
- 175 people
- Sponsor
- Istanbul University - Cerrahpasa
Pain, Traumatic Brain Injury
The NRC Dataset. Developing a Minimum Dataset for Multidisciplinary Rehabilitation: a Modified E-Delphi Study
Several rehabilitation datasets are presently in use for specific patient groups in England. The 'National Clinical Audit of Specialist Rehabilitation for patients with complex needs following major injury' (NCASRI) evaluated…
- Conditions
- Pain, Traumatic Brain Injury, Major Trauma, Multiple Sclerosis
- Trial name
- NCT06726135
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- ThomasCorbett
Multiple Sclerosis
The Effects of Synchronous and Asynchronous Pilates Training Based on Telerehabilitation on Core Stabilization, Balance, Cognitive Functions, and Quality of Life in Individuals With Multiple Sclerosis: A Single-Blind Randomized Controlled Trial
This study will compare live video-based and prerecorded video-based Pilates programs in 38 adults aged 18-65 years with multiple sclerosis. Participants will be randomly assigned to one of two groups.
- Trial name
- NCT07893925
- Testing
- Synchronous Telerehabilitation-Based Pilates, Asynchronous Telerehabilitation-Based Pilates
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people
- Sponsor
- Yuzuncu Yil University
Diabetes Mellitus, Type 1
Sleep, Coping and Executive Functioning in Youth With Type 1 Diabetes
The purpose of this exploratory study is to evaluate the characteristics of sleep, perceptions of barriers and facilitators to adequate sleep, and the associations among sleep characteristics, executive functioning, coping…
- Trial name
- SleepT1D (NCT02908555)
- Testing
- No intervention
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Yale University
HIV Infections
The Use of Bacteriophage Phi X174 to Assess the Immune Competence of HIV-Infected Patients In Vivo
The objective of this study is to evaluate the safety and utility of bacteriophage phi X174 immunization as a tool to assess the immune competence of HIV-infected patients at different stages of disease in vivo, and to assess the…
- Trial name
- NCT00001540
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Multiple Sclerosis, Peripheral Neuropathy
Effects of Meditation on Multiple Sclerosis and Peripheral Neuropathy
This study will evaluate the effects of mindfulness and concentration meditation on pain, fatigue, and physical functioning in patients with either multiple sclerosis or peripheral neuropathy.
- Trial name
- NCT00981643
- Testing
- Meditation instruction and practice
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- The Cleveland Clinic
CVA (Cerebrovascular Accident)
Wearable Robotic Functional Assistance for Stroke Rehabilitation
This study aims to evaluate the effectiveness of using the myomo e100 wearable robotic rehabilitation system for increasing functional independence and long term rehabilitation of chronic stroke victims with a hemiparetic upper…
- Trial name
- NCT00396708
- Testing
- myomo e100 neurorobotic elbow brace
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Myomo
Out of Hospital Cardiac Arrest, Inflammatory Response
Hypothermia After Cardiac Arrest - Effects on Myocardial Function and Inflammatory Response.
The on-going randomized clinical trial TTM2 (Target Hypothermia Versus Targeted Normothermia After Out-of-hospital Cardiac Arrest, NCT02908308) investigates if there is a difference in mortality, neurological function or quality…
- Conditions
- Out of Hospital Cardiac Arrest, Inflammatory Response, Ischemia Reperfusion Injury, Hypothermia
- Trial name
- IH3 (NCT03743584)
- Testing
- Targeted temperature management, Standard care, early treatment of fever
- Where
- Norway
- Volunteers
- 26 people
- Sponsor
- Oslo University Hospital
Stroke, Upper Extremity Paresis
Functional Recovery in Stroke Patients With Task-Specific Robot-Aided Arm Therapy
The goal of this study is to determine whether task-oriented, robot-aided therapy is more effective than conventional physical and occupational therapy at promoting functional recovery of the affected arm in chronic hemiparetic…
- Trial name
- NCT00719433
- Testing
- robot therapy (ARMin), conventional therapy
- Where
- Switzerland
- Volunteers
- 76 people
- Sponsor
- University of Zurich
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.