Clinical trials: Immune System Function
Asthma in Children
Video Game-Based and Conventional Breathing Exercises on Pulmonary and Extrapulmonary Features in Children with Asthma
Conventional breathing exercises are recommended as a support to drug therapy, which is the primary treatment modality for symptom management in asthma patients.
- Trial name
- NCT06546566
- Testing
- Video Game-Based Breathing Exercises, Conventional Breathing Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Atlas University
Type 1 Diabetes Mellitus
Psychosocial Functioning in Young Adults With Type 1 Diabetes
Background: The often studied psychosocial correlates that relate to health outcomes in adolescents with Type 1 Diabetes (T1D) are factors such as self-efficacy, depression, distress, quality of life, and adherence.
- Trial name
- NCT02874612
- Testing
- Psychosocial Survey Questionnaires
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Multiple Sclerosis
Psychometric Properties Upper Limb Function Measures Multiple Sclerosis
Current study will investigate de quality (psychometric properties) and clinical utility of several measures of upper limb function, according to disability level.
- Trial name
- MCS-III-UL (NCT02339675)
- Testing
- conventional MS rehabilitation
- Where
- Belgium
- Volunteers
- 136 people
- Sponsor
- Hasselt University
Diabetes Mellitus - Type 1, Diabetes Mellitus - Type 2
Diabetes Visual Function Supplement Study
This study will evaluate the effects of a novel multi-component dietary supplement on the visual function and retinal structure of patients with diabetes with both no diabetic retinopathy and mild to moderate diabetic…
- Conditions
- Diabetes Mellitus - Type 1, Diabetes Mellitus - Type 2, Non-proliferative Diabetic Retinopathy
- Trial name
- DiVFuSS (NCT01646047)
- Testing
- multi-component nutritional supplement capsules, multi-component dietary supplement
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- ZeaVision, LLC
Multiple Myeloma
A Safety and Efficacy of Pomalyst® Capsules Under the Actual Use in All Patients Who Are Treated With Pomalyst at a Dose of 1 mg, 2 mg, 3 mg, or 4 mg
1. Planned enrollment period One year (The planned number of patients to be enrolled is set to 400 patients.) Since all patients who are prescribed with Pomalyst are registered in RevMate®, enrollment using the Registration Form…
- Trial name
- NCT02921828
- Where
- 2 sites in United States, Japan
- Volunteers
- 1,149 people
- Sponsor
- Celgene
Diabetes Mellitus, Type 1
Prolonged Remission Induced by Phenofibrate in Children Newly Diagnosed With Type 1 Diabetes.
The goal of this clinical trial is to evaluate of the effect of phenofibrate on the functions of beta cells in children with new diagnosis of type 1 diabetes.
- Trial name
- PRIFEN (NCT05909800)
- Testing
- Phenofibrate
- Where
- 2 sites in Poland
- Volunteers
- 102 people
- Sponsor
- Medical University of Warsaw
Cognitive Disorders, HIV Infections
HIV Levels in Cerebrospinal Fluid and Brain Function in Patients Receiving Anti-HIV Drugs
The purpose of this study is to see whether anti-HIV drugs that reduce HIV in the blood also reduce HIV in the cerebrospinal fluid (CSF). CSF is the fluid found around the brain and spinal cord.
- Trial name
- NCT00001103
- Where
- 26 sites in United States, Puerto Rico
- Volunteers
- 100 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Asthma (Diagnosis)
Effects of Wet Cupping Therapy in Patients With Asthma
This study evaluated the effects of wet cupping therapy on immune modulation, pulmonary function, and quality of life in adults with asthma.
- Trial name
- WCT-ASTHMA (NCT07764042)
- Testing
- Wet Cupping Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Medipol University
Sinusitis, Nasal Polyps
Comparison of Daily Mometasone Furoate Nasal Spray Alone Versus a Combination With Montelukast for Treatment of Chronic Rhinosinusitis With Asthma After Functional Endoscopic Sinus Surgery
1. objectives. To compare the efficacy and the safety of mometasone furoate nasal spray (MFNS; Nasonex 200μg, daily) alone versus a combination with montelukast (singulair 10mg, daily) in chronic rhinosinusitis (CRS) with asthma…
- Conditions
- Sinusitis, Nasal Polyps, Asthma
- Trial name
- NCT02110654
- Testing
- Montelukast, mometasone furoate nasal spray
- Where
- China
- Volunteers
- 50 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
CAR T-cell Therapy, Autoimmune Hemolytic Anemia
Brain Function and Psychological Changes Related to Cell Therapy for Autoimmune Hemolytic Anemia
Cell therapy is an innovative treatment with significant efficacy in hematologic and certain autoimmune diseases. Although it offers potential benefits for autoimmune hemolytic anemia (AIHA), it may result in cognitive and other…
- Conditions
- CAR T-cell Therapy, Autoimmune Hemolytic Anemia, Brain Function, Psychological Well-Being
- Trial name
- NCT06921980
- Testing
- Brain function and psychological assessment
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Institute of Hematology & Blood Diseases Hospital, China
Arthritis, Rheumatoid
Long-Term Safety Follow-Up Of Subjects Previously Enrolled In Rheumatoid Arthritis Studies Of CP-690,550
The purpose of this study is to follow the health of subjects who have previously been enrolled in studies of CP-690,550 for treatment of their rheumatoid arthritis.
- Trial name
- NCT00414661
- Testing
- CP-690,550
- Where
- 72 sites in United States, Argentina and 19 more
- Volunteers
- 162 people
- Sponsor
- Pfizer
Benign Nontoxic and Toxic Goiter, Graves' Disease
rhTSH, Thyroid Size, and Radioiodine Therapy in Benign Goiter
The trials in this protocol deals with the effect of pretreatment with rhTSH on radioiodine treatment of thyroid size and function, in patients with nontoxic and toxic nodular goiter.
- Trial name
- NCT00145366
- Testing
- Recombinant human thyrotropin (Thyrogen)
- Where
- Denmark
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Low Back Pain, Mechanical, Biofeedback, Pain, Chronic, Low Back Pain
The Effects of Dynamic Neuromuscular Stabilization Exercises in Addition to Conventional Treatment on Functional Capacity, Core Stabilization Muscle Strength, and Balance in Female Patients With Chronic Low Back Pain
Low back pain, which is currently considered a public health problem, is commonly encountered. A significant proportion of low back pain cases is of mechanical origin.
- Trial name
- NCT07199842
- Testing
- Dynamic Neuromuscular Stabilization Exercises in Addition to Conventional Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Safiye Esin
Multiple Sclerosis
The Effects of Synchronous and Asynchronous Pilates Training Based on Telerehabilitation on Core Stabilization, Balance, Cognitive Functions, and Quality of Life in Individuals With Multiple Sclerosis: A Single-Blind Randomized Controlled Trial
This study will compare live video-based and prerecorded video-based Pilates programs in 38 adults aged 18-65 years with multiple sclerosis. Participants will be randomly assigned to one of two groups.
- Trial name
- NCT07893925
- Testing
- Synchronous Telerehabilitation-Based Pilates, Asynchronous Telerehabilitation-Based Pilates
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people
- Sponsor
- Yuzuncu Yil University
Type 1 Diabetes
EMERALD: Effects of Metformin on Cardiovascular Function in Adolescents With Type 1 Diabetes
Diabetes is increasingly common among youth, forecasting early complications. Type 1 (T1D) cause early heart disease, shortening lifespan despite modern improvements in control of blood sugars and other risk factors for heart…
- Trial name
- EMERALD (NCT01808690)
- Testing
- Metformin
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of Colorado, Denver
Severe, Septic
Effects of Alkaline Phosphatase on Renal Function in Septic Patients
Septic shock is the most common cause of death in patients requiring intensive care. The kidney is one of the first organs to fail, stressing the importance to search for clinical interventions that may protect the kidneys during…
- Conditions
- Severe, Septic, Shock
- Trial name
- NCT00457613
- Testing
- bolus injection, followed by a continuous infusion ( 24 h) (Alkaline phosphatase)
- Where
- Netherlands
- Volunteers
- 15 people
- Sponsor
- Radboud University Medical Center
Multiple Sclerosis
Supported Treadmill Training for Progressive Multiple Sclerosis
This study is a pilot trial to evaluate the effects of supported treadmill walking in patients with primary progressive multiple sclerosis (MS) on functional and psychosocial outcomes.
- Trial name
- NCT01339234
- Testing
- Body-weight supported treadmill training
- Where
- Canada
- Volunteers
- 6 people
- Sponsor
- Hicks, Audrey, Ph.D.
Women With Multiple Sclerosis, Multiple Sclerosis
The Effect of DNS-Based Training Combined With PFMT on LUTS and Pelvic Floor Functions in Women With MS
The goal of this randomized controlled trial is to investigate whether adding Dynamic Neuromuscular Stabilization (DNS)-based training to Pelvic Floor Muscle Training (PFMT) can improve lower urinary tract symptoms (LUTS) and…
- Conditions
- Women With Multiple Sclerosis, Multiple Sclerosis, Lower Urinary Track Symptoms, Pelvic Floor Disorder
- Trial name
- NCT07166809
- Testing
- Pelvic Floor Muscle Training (PFMT), Pelvic Floor Muscle Training combined with Dynamic Neuromuscular Stabilization (PFMT+DNS)
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Ondokuz Mayıs University
HIV Infections
Developing a Functional Cure for HIV Disease: Clinical Specimen Collection From HIV Positive Individuals
Clinical specimens are required from HIV positive individuals with viremia controlled by antiretroviral therapy to complete process development for a genetically modified autologous T cell product, AGT103-T.
- Trial name
- NCT03215004
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- American Gene Technologies International Inc.
Sarcoidosis, Pulmonary Rehabilitation
Comparison of the Effects of Yoga and Conventional Physiotherapy Programs in Sarcoidosis
Sarcoidosis is a multisystem disease, characterized by the formation of immune granulomas with various clinical symptoms depending on the involved organs, which can involve many organs and systems associated with emotional and…
- Conditions
- Sarcoidosis, Pulmonary Rehabilitation, Yoga
- Trial name
- NCT06848608
- Testing
- traditional physiotherapy group, yoga program
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Saglik Bilimleri Universitesi
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