Clinical trials: Immune System Function
Asthma; Status
Effects of Swedish Massage Prior Circuit Breathing Training on Asthma
The objective of this study was to determine the effects of Swedish massage prior circuit breathing training on asthma control and respiratory function in patients with asthma.
- Trial name
- NCT06407011
- Testing
- Control, Swedish massage prior circuit breathing training group (SBT), Circuit breathing training group (CBT)
- Where
- Thailand
- Volunteers
- 30 people
- Sponsor
- Chulalongkorn University
Immune Dysfunction
Fish Oils and Soybean Lecithin Supplementation Modulate Immune Function in Runners
The purpose of this study was evaluate the comparative effects of FO rich in EPA (FO-EPA) and FO rich in DHA (FO-DHA) on inflammation and neutrophil properties after a prolonged and strenuous exercise.
- Trial name
- NCT03364699
- Testing
- dietary supplementation, Exercise
- Where
- Brazil
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Asthma, Inflammation
Vascular Implications of a Naturally Occurring Asthma Exacerbation
Although asthma is a disease of the airways, research is now showing that asthmatics are more likely to develop cardiovascular disease (CVD) compared to non-asthmatics.
- Conditions
- Asthma, Inflammation, Cardiovascular Risk Factor
- Trial name
- NCT03679299
- Testing
- Observational - No intervention
- Where
- 2 sites in Canada
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Rheumatoid Arthritis (RA)
Effect of Subthreshold Stimulation on Fatigue in Rheumatoid Arthritis
The study will include 2 groups. The study group will receive subthreshold stimulation, while the control group will receive sham treatment.
- Trial name
- NCT07367438
- Testing
- Subthreshold stimulation
- Volunteers
- 84 people
- Sponsor
- Beni-Suef University
Type 1 Diabetes, Heart Disease
Haptoglobin Phenotype, Vitamin E and High-density Lipoprotein (HDL) Function in Type 1 Diabetes
The purpose of the study is to determine whether the function of the good cholesterol (HDL cholesterol) as well as its subfractions (via NMR spectroscopy) is altered among people with type 1 diabetes and a variation in the…
- Trial name
- HAP-E (NCT01098994)
- Testing
- Vitamin E, Dummy pills
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- University of Pittsburgh
Multiple Sclerosis (MS) - Relapsing-remitting
Effects of Ublituximab on Motor Functions in Multiple Sclerosis
The purpose of this study is to test if ublituximab changes walking functions and fall risk in people with relapsing multiple sclerosis (RMS). Twenty-five qualified people with RMS will undergo a 48-week ublituximab treatment.
- Trial name
- U-PACE (NCT06629428)
- Testing
- Ublituximab
- Where
- 2 sites in United States
- Volunteers
- 25 people
- Sponsor
- Georgia State University
Asthma
Small Airway Function of Fluticasone/Formoterol (Flutiform®) and Fluticasone/Salmeterol
The purpose of this study is to demonstrate superiority of Fluticasone/Formoterol (Flutiform®) to Fluticasone/salmeterol based on the small airway function by assessing the Impulse Oscillometic System (IOS) in uncontrolled asthma…
- Trial name
- RECONFFIRM (NCT02491970)
- Testing
- Fluticasone/Formoterol, Fluticasone/Salmeterol
- Volunteers
- 15 people
- Sponsor
- Mundipharma Korea Ltd
Secondary Progressive Multiple Sclerosis
Functional Electrical Stimulation for Individuals With Secondary Progressive Multiple Sclerosis
Secondary progressive multiple sclerosis (SPMS) is a subtype of multiple sclerosis (MS) for which there are no existing therapies that alter the disease course.
- Trial name
- NCT01647321
- Testing
- Active cycling, Passive cycling
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Johns Hopkins University
Multiple Sclerosis, Relapsing-Remitting
Evaluation of the Impact of Lesions of the Motor and Proprioceptive Brain and Pan-medullary Pathways on Their Clinically and Electrophysiologically Assessed Function in Multiple Sclerosis
Multiple Sclerosis (MS) is the most common acquired neurological disease leading to disability, especially ambulatory, in young adults.
- Trial name
- MS-TRACTS (NCT04220814)
- Testing
- MRI, Electrophysiology
- Where
- 2 sites in France
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Rennes University Hospital
Immune System, Stress
Impact of Peanut Consumption on Stress, Immune Function, Inflammation, and Cardiovascular Health in High-Stress Individuals
The purpose of this research is to determine whether peanut consumption improves indicators of cardiovascular disease (CVD) risk in human subjects following the consumption of study foods.
- Conditions
- Immune System, Stress, Chronic Stress, Cardiovascular Health
- Trial name
- NCT07735221
- Testing
- Peanuts, roasted, salted with skins, Isocaloric food
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- USDA, Western Human Nutrition Research Center
Multiple Sclerosis
Plantar Sensitivity Training and Aerobic Exercise Training in Patients With Multiple Sclerosis (PlaSTAcET Study)
The aim of this thesis study is to examine whether plantar sensory training given in addition to aerobic exercise training has an additional contribution to balance, functional capacity, walking and proprioception in patients…
- Trial name
- NCT05937971
- Testing
- plantar sensitivity training, aerobic exercise training
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Istanbul Arel University
Graves Disease, COVID-19
To Investigate the Effect of 2019 Novel Coronavirus Infection on the Condition of Patients With Hyperthyroidism
The goal of this observational study is to learn about the correlation between COVID-19 and hyperthyroidism in Patients with hyperthyroidism complicated with COVID-19.
- Trial name
- NCT06204393
- Testing
- Thyroid metabolic index
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Qilu Hospital of Shandong University
Hepatic Impairment, Healthy Volunteers
A Study to Evaluate ASP0367 in Participants With Mild/Moderate Hepatic Impairment Compared to Participants With Normal Hepatic Function
The purpose of this study is to evaluate the effect of ASP0367 in participants with mild and moderate hepatic impairment compared to healthy participants with normal hepatic function.
- Trial name
- NCT04942964
- Testing
- Bocidelpar
- Where
- 3 sites in United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Global Development, Inc.
Endometrial Carcinoma, Recurrent Fallopian Tube Carcinoma
An Automated Personalized Physical Activity Intervention to Improve Immune Function and Clinical Outcomes in Stage II-IV Ovarian, Primary Peritoneal or Fallopian Tube Cancer and Newly Diagnosed Endometrial Cancer, Life on the Go 3 Study
This clinical trial compares the effect of an automated personalized physical activity intervention supported by wearable technology to standard of care on physical activity levels and quality of life in patients with stage II…
- Conditions
- Endometrial Carcinoma, Recurrent Fallopian Tube Carcinoma, Recurrent Ovarian Carcinoma, Recurrent Primary Peritoneal Carcinoma
- Trial name
- NCT06855706
- Testing
- Behavioral Intervention, Best Practice, Biospecimen Collection
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Roswell Park Cancer Institute
Training Study, Multiple Sclerosis
Low-Load Blood Flow Restriction on Patients With Multiple Sclerosis
This research is being done to compare the current standard of care for strength training for patients with Multiple Sclerosis to lightweight resistance training with blood flow restriction.
- Conditions
- Training Study, Multiple Sclerosis, Blood Flow Restriction
- Trial name
- NCT05177952
- Testing
- Blood Flow Restriction, Standard of Care
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Central Florida
Multiple Sclerosis
KITAMS: Kinesio Tape and Physical Function in Persons With Multiples Sclerosis
Multiple sclerosis (MS) is a disease that causes damage within the central nervous system and results in deficits of body functions.
- Trial name
- KITAMS (NCT03804047)
- Testing
- kinesio tape
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Northern Illinois University
Multiple Sclerosis
Correlation Between Cognitive Functions and MRI in Multiple Sclerosis
The purpose of this study is to determine whether there is a correlation between cognitive functions and volume of specific brain area measured in MRI of multiple sclerosis patients.
- Trial name
- NCT00423111
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Sheba Medical Center
Asthma
Lung Function of Asthmatic Children by Nebulized MgSO4
Asthma is a common chronic respiratory illness which results in frequent wheezing, cough,reduced quality of life. Standard treatment for asthma attack includes oxygen therapy, β2-agonists (e.g.
- Trial name
- NCT01799109
- Testing
- Magnesium Sulfate & albuterol, albuterol, magnesium
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Chongqing Medical University
Juvenile Idiopathic Arthritis
PEAK Study (Physical Exercise and Activity in Kids)
The objectives of this study are to study the effect of formal exercise training on motor function and overall physical fitness in children with arthritis. A 12-week comprehensive exercise program will be used.
- Trial name
- NCT00213187
- Testing
- Aerobic and Qi gong Exercise
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- The Hospital for Sick Children
Out of Hospital Cardiac Arrest, Inflammatory Response
Hypothermia After Cardiac Arrest - Effects on Myocardial Function and Inflammatory Response.
The on-going randomized clinical trial TTM2 (Target Hypothermia Versus Targeted Normothermia After Out-of-hospital Cardiac Arrest, NCT02908308) investigates if there is a difference in mortality, neurological function or quality…
- Conditions
- Out of Hospital Cardiac Arrest, Inflammatory Response, Ischemia Reperfusion Injury, Hypothermia
- Trial name
- IH3 (NCT03743584)
- Testing
- Targeted temperature management, Standard care, early treatment of fever
- Where
- Norway
- Volunteers
- 26 people
- Sponsor
- Oslo University Hospital