Clinical trials: Immunoglobulin Prophylaxis
Pregnancy Related
Human Anti-D (rh) Immunoglobulin (Rhesoglobin) Efficacy, Safety and Some Pharmacokinetics Parameters in Pregnant Women
Rhesus conflict between mother and fetus is due to the different antigenic composition of erythrocytes. During the first pregnancy, sensitization of the mother to fetal erythrocytes rhesus D (RhD) antigens is formed.
- Trial name
- NCT05245734
- Testing
- Human Anti-D (rh) immunoglobulin
- Where
- 16 sites in Ukraine
- Volunteers
- 281 people
- Sponsor
- Biopharma Plasma LLC
Immunoglobulin Prophylaxis, Cytomegalovirus Infections
Immunoglobiulin-specific Prophylaxis of Citomegalovirus Infections in Immunocompromised Children Undergoing Allogeneic Hematopoietic Stem Cell Transplantation
Human cytomegalovirus (CMV) is a globally prevalent, human-specific herpesvirus characterised by a lifelong latency after primary infection, an often asymptomatic reactivation and affecting up to 100% of adults based on region…
- Conditions
- Immunoglobulin Prophylaxis, Cytomegalovirus Infections, Allogeneic Hematopoietic Stem Cell Transplantation, Transplant-Related Disorder
- Trial name
- NCT07013370
- Testing
- Anti-CMV immunoglobulins [Megalotect (R)]
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Antonello Di Paolo, M.D., Ph.D.
Secondary Immune Deficiency Disorder
Humoral Immunodeficiency in CLL and Therapy With Subcutaneous Ig
Patients with chronic lymphocytic leukemia (CLL) are at increased risk of infections as compared to age matched controls, with infections being a major cause of morbidity and mortality.
- Trial name
- NCT03730129
- Testing
- Hizentra
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Rochester General Hospital
Acute Graft-versus-Host Disease
Anti-CD25 rhMAb for aGVHD Prevention in High-Risk Adults Using the daGOAT Model
To assess the efficacy and safety of using recombinant humanized anti-CD25 monoclonal antibody injection as a prophylactic strategy for reducing the incidence of severe acute graft-versus-host disease (aGVHD) in adult patients at…
- Trial name
- NCT06880419
- Testing
- Recombinant Humanized Anti-CD25 Monoclonal Antibody Injection
- Where
- China
- Volunteers
- 174 people
- Sponsor
- Institute of Hematology & Blood Diseases Hospital, China