Clinical trials: Immunologic Factors
HIV Infections
Safety and Acceptability of the Anti-Microbe Vaginal Gel, PMPA Gel
The purpose of this study is to evaluate the PMPA gel, which kills microbes, in HIV-infected and HIV-uninfected women. The majority of new HIV infections occur through heterosexual contact.
- Trial name
- NCT00028132
- Testing
- Tenofovir
- Where
- 5 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV/AIDS
DASH - Decision Making in Adolescent Sexual Health
This is a randomized controlled trial to contrast an intervention that relies on well-developed cognitive control systems (Motivational Interviewing; MI) to an intervention that relies on a more basic response to scheduled reward…
- Trial name
- DASH (NCT02141646)
- Testing
- Motivational Interviewing, Behavioral Skills Training
- Where
- United States
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
HIV Infections
Examining Factors That May Influence Resistance to HIV-1 Infection
Some people who are exposed to the HIV-1 virus are capable of either controlling or completely preventing viral infection. Multiple genetic factors may contribute to preventing or controlling HIV-1 infection.
- Trial name
- NCT00351442
- Where
- 3 sites in Uganda, United Kingdom
- Volunteers
- 522 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Lactational Amenorrhea, Body Weight Changes
Effects of Exercise and Yogurt on Bone Mineral Density and Immunological Factors in Human Milk: The MEEMA Study
Obesity in America has risen to epidemic levels over the past 20 years. For women, childbearing itself could be a contributing factor to this high prevalence of excess weight.
- Conditions
- Lactational Amenorrhea, Body Weight Changes, Bone Loss
- Trial name
- MEEMA (NCT03732261)
- Testing
- Exercise and dietary
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- North Carolina Agriculture & Technical State University
Virus Diseases, RNA Virus Infections
Safety, Tolerability and Immunogenicity of a Plant-made H7 Virus-like Particle (VLP) Influenza Vaccine in Adults.
A phase I trial conducted in a single centre, observer-blind, randomized, dose-ranging, placebo-controlled study to evaluate the safety, tolerability, and immunogenicity of 2 intramuscular injections of plant-based H7 VLP…
- Conditions
- Virus Diseases, RNA Virus Infections, Respiratory Tract Diseases, Respiratory Tract Infections
- Trial name
- NCT02022163
- Testing
- Low dose of H7 VLP vaccine + Alhydrogel, Med dose of H7 VLP vaccine + Alhydrogel, High dose of H7 VLP vaccine + Alhydrogel
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Medicago
HIV Infections, HIV Seronegativity
HIV Incidence and Participation Retention in Pune, India
The purpose of this study is to ensure that the HIV Prevention Trials Unit (HPTU) in Pune will be able to enroll and retain participants for 2 upcoming HPTN clinical trials.
- Trial name
- NCT00028119
- Where
- India
- Volunteers
- 1,070 people, healthy volunteers welcome
- Sponsor
- HIV Prevention Trials Network
Hereditary Angioedema
Safety and Pharmacokinetics of GNR-038 in Healthy Volunteers
It is an open-label dose-escalating study in sequential cohorts to assess safety and pharmacokinetics of GNR-038.
- Trial name
- NCT04557319
- Testing
- GNR-038, 25 МЕ/kg, GNR-038, 50 МЕ/kg, GNR-038, 100 МЕ/kg
- Where
- Russia
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- AO GENERIUM