Clinical trials: Impact on Patients
Heart Failure
Impact of Blood Glucose Levels on in ICU Morbidity and Mortality in Patients With Acute Decompensated Heart Failure
To evaluate the effect of blood glucose level at admission and glucose variability during ICU admission and their effect on in-hospital morbidity and mortality in patients admitted with acute decompensated heart failure
- Trial name
- NCT06453967
- Testing
- blood glucose levels
- Volunteers
- 96 people
- Sponsor
- Assiut University
Non-small Cell Lung Cancer, Quality of Life
LIFE - Lung Cancer, Immunotherapy, Frailty, Effect
The LIFE study (Lung cancer, Immunotherapy, Frailty, Effect) is investigating the unselected 'real life' non-small cell lung cancer (NSCLC) population treated with immune checkpoint inhibition.
- Conditions
- Non-small Cell Lung Cancer, Quality of Life, Brain Metastases, Venous Thromboembolism
- Trial name
- NCT03870464
- Testing
- CT-scans extended, MRI scan of the brain, Prospective registration of irAEs
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- University of Southern Denmark
Paroxysmal Atrial Fibrillation
Quality of Life Influencing Factors
Background: quality of life is impaired in patients with paroxysmal atrial fibrillation. The purpose of this study is to explore the mediating effects of self-efficacy, coping, depression, and anxiety on the quality of life of…
- Trial name
- NCT05974098
- Testing
- Observational study
- Where
- China
- Volunteers
- 178 people
- Sponsor
- Peking University People's Hospital
Myocardial Infarction
The Impact of Text Messaging on Medication Adherence and Exercise Regimen Among Post-myocardial Infarction Patients
The purpose of this study is to assess the impact of text message reminders on adherence to medications and exercise in patients recently discharged from the hospital after a myocardial infarction (MI).
- Trial name
- NCT02783287
- Testing
- Text message reminder for medication adherence, Text message reminder for exercise regimen
- Volunteers
- 84 people
- Sponsor
- Brigham and Women's Hospital
Surgery
Evaluation of Coaching Impact on Surgical Outcomes
This two arms parallel cluster-randomized trial will evaluate the impact of a customized coaching program for surgeons on the occurrence of patient major adverse events.
- Trial name
- TopSurgeons (NCT04532658)
- Testing
- Coaching program
- Where
- France
- Volunteers
- 20,791 people
- Sponsor
- Hospices Civils de Lyon
SARS-CoV 2
Impact of Zinc and Vitamin D3 Supplementation on the Survival of Aged Patients Infected With COVID-19
Mortality from Covid-19 increases with age, reaching 14.8% from the age of 80. The severity of the infection is linked to the acute respiratory distress syndrome (ARDS) which requires intensive care.
- Trial name
- ZnD3-CoVici (NCT04351490)
- Testing
- Zinc gluconate, 25-OH cholecalciferol
- Sponsor
- University Hospital, Lille
Cystic Fibrosis in Children
Clinical Trial to Assess Influence of MyCyFAPP Use on GI Related QOL in Children With Cystic Fibrosis
Interventional trial to study the influence of the use of MyCyFAPP (mobile application) on the gastro-intestinal related quality of life.
- Trial name
- MyCyFAPP (NCT03292718)
- Testing
- MyCyFAPP
- Volunteers
- 200 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
HRAS Gene Mutation, HNSCC
Safety and Efficacy of Tipifarnib in Head and Neck Cancer With HRAS Mutations and Impact of HRAS on Response to Therapy
An international, multicenter, open-label, 2 cohort, non-comparative, pivotal study evaluating the efficacy of tipifarnib in HRAS mutant HNSCC (AIM-HN).
- Trial name
- AIM-HN/SEQ-HN (NCT03719690)
- Testing
- Tipifarnib, HRAS Detection Assay
- Where
- 102 sites in United States, Australia and 14 more
- Volunteers
- 296 people
- Sponsor
- Kura Oncology, Inc.
Pain, Satisfaction, Patient
Examining the Impact of Mindfulness on Patients' Experience of Osteopathic Manipulation
This is a single site, two-arm, parallel group pilot randomized controlled trial examining the effect of coupling a brief mindfulness-based intervention with an osteopathic manipulation session for pain patients.
- Trial name
- NCT04477278
- Testing
- Mindfulness Meditation, History of Osteopathy
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Utah
Sleep Disorders
Sleep Disorders and Their Impact on Patients With Ménière's Disease
Ménière's disease was first described by Prosper Ménière in 1861 as a balance disorder originating in the inner ear. It is diagnosed based on a characteristic clinical triad of low-frequency hearing loss, tinnitus, and vertigo…
- Trial name
- SoM (NCT07299578)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Strasbourg, France
To Explore the Influence of CRRT Nursing Team Management Plan on the Prognosis of SAKI Patients
Impact of the CRRT Management Protocol on Prognostic Outcome in Patients With Septic Acute Kidney Injury
The implementation of CRRT nursing team management program in the treatment of SAKI can significantly reduce the incidence of adverse events and complications in CRRT nursing, which has a positive role in improving the success…
- Trial name
- NCT06083285
- Testing
- Implement the CRRT specialist nursing group management program on the basis of routine care
- Where
- China
- Volunteers
- 76 people
- Sponsor
- Xinjiang Medical University
Type 2 Diabetes Mellitus
COVID-19 Lockdown Related Telemedicine for Type 2 Diabetes
At present, in order to cope with the global pandemic of the COVID-19 virus, governments have introduced corresponding measures, COVID-19 lockdown is one of the most important measures.
- Trial name
- NCT04723550
- Testing
- Hospital telemedicine management system, Usual care
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Wenwen Yin
Lupus Erythematosus, Systemic
Physical Activity in Patients With Systemic Lupus Erythematosus
Background. Systemic lupus erythematosus is a chronic autoimmune disease. Among its main clinical manifestations are musculoskeletal symptoms such as myopathies, arthritis, arthralgias or osteonecrosis.
- Trial name
- NCT06919250
- Testing
- Patients with systemic lupus erythematosus
- Where
- Spain
- Volunteers
- 63 people
- Sponsor
- University of Oviedo
Cardiovascular Injury, Prostate Carcinoma
Cardiac MRI in Measuring the Impact of Anti-androgen Treatment on Cardiac Function in Patients With Prostate Cancer
Learning about the impact of anti-androgen treatment has on cardiac function in patients with prostate cancer may help plan treatment and help patients live more comfortably.
- Trial name
- NCT02722525
- Testing
- Magnetic Resonance Imaging, Exercise Intervention, Perfusion Magnetic Resonance Imaging
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
HIV/AIDS
Pediatric Decentralization of ART in South Africa
The decentralization study will describe children taking antiretroviral therapy (ART) at a larger health facility in the Eastern Cape province of South Africa, between the years of 2004-2013.
- Trial name
- NCT03049891
- Testing
- Data abstraction, Tracing questionnaire, Tier.net
- Where
- 15 sites in South Africa
- Volunteers
- 1,583 people
- Sponsor
- Columbia University
Myocardial Infarction, Acute Coronary Syndrome
Impact at One Year of a Secondary Prevention Educational Program on Cardiovascular Risk Factors
In secondary prevention, the beneficial role of cardiac rehabilitation programs after myocardial infarction, percutaneous coronary intervention or coronary artery bypass is now well established.
- Trial name
- OLIMPIC (NCT00758810)
- Where
- 4 sites in France
- Volunteers
- 354 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Transcatheter Aortic Valve Replacement, Hemodynamic Stability
Crystalloid vs Colloid for Hemodynamics During Anesthesia Induction in TAVR Patients
The purpose of this study is to evaluate whether the administration of 5 ml/kg of colloid solution prior to anesthesia induction, compared with 5 ml/kg of lactated Ringer's solution, can reduce hemodynamic fluctuations during the…
- Conditions
- Transcatheter Aortic Valve Replacement, Hemodynamic Stability, Anesthesia Induction
- Trial name
- CHAIN-T (NCT07329660)
- Testing
- Hydroxyethyl starch 130/0.4, Lactate Ringer's Solution
- Volunteers
- 116 people
- Sponsor
- Air Force Military Medical University, China
Respiratory Insufficiency, Hematologic Malignancy
Systematic Evaluation by an Intensivist of Hematological Malignancy Patients Presenting With Acute Respiratory or Hemodynamic Failure
Over the last two decades, the number of patients with hematological malignancies (HMs) admitted to the ICU increased and their mortality has dropped sharply.
- Trial name
- CAREHEMA (NCT03399149)
- Testing
- Systematic evaluation by an intensivist
- Where
- 2 sites in France
- Volunteers
- 221 people
- Sponsor
- University Hospital, Grenoble
COVID 19
Impact of Nasal Saline Irrigations on Viral Load in Patients With COVID-19
Nasal saline irrigations are a safe and commonly used mechanism to treat a variety of sinonasal diseases including sinusitis, rhinitis, and upper respiratory tract infections.
- Trial name
- NCT04347538
- Testing
- Saline Nasal Irrigation
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- Vanderbilt University Medical Center
Cancer
Impact of Therapeutic Osteopathy-hypnosis on Cancer Patients.
Osteopathy is recognized as a beneficial complementary approach for cancer patients. By addressing tissue mobility, circulation, and muscle tension, it helps improve physical comfort, reduce musculoskeletal pain, and foster…
- Trial name
- HYPOSTEO (NCT07860476)
- Testing
- Osteopathy, Hypnosis
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Institut Rafael