Clinical trials: Impact on Patients
Adolescent Idiopathic Scoliosis (AIS), Exercise (EX)
Effects of Lumbar Traction Combined With 3D Exercise Therapy on Adolescent Idiopathic Scoliosis
Adolescent Idiopathic Scoliosis (AIS) is a three-dimensional spinal deformity that appears during adolescence without an identifiable underlying cause.
- Trial name
- NCT07448688
- Testing
- Lumbar Mechanical Traction
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Şahide Eda ARTUÇ
Coronary Artery Disease
Impact of Health Literacy on Outcomes and Effectiveness of Shared Decision Making Programs in Patients With Chronic Diseases
Study objective was to explore the impact of health literacy on effectiveness of an educational intervention describing life-style and behavior modification for patients "Living with Coronary Artery Disease." Our hypothesis was…
- Trial name
- NCT01083862
- Testing
- Educational Intervention - Text plus DVD/VHS, Educational Intervention - Text Only
- Where
- United States
- Volunteers
- 187 people
- Sponsor
- University of Cincinnati
Sars-CoV2, Critical Illness
COVID-19 and ICU-acquired MDR Bacteria
This multicenter before-after study aimed to determine the impact of infection related to SARS-CoV-2 on the incidence of ICU-acquired multidrug resistant (MDR) bacteria.
- Trial name
- COVID-BMR (NCT04378842)
- Where
- 7 sites in France
- Volunteers
- 368 people
- Sponsor
- University Hospital, Lille
Post-COVID-19 Syndrome
Impact Of Sensory Re-Education Paradigm On Sensation And Quality Of Life In Patients Post-Covid 19 Polyneuropathy
This study will be conducted to investigate the effect of a sensory re-education paradigm on sensation and proprioception in patients with post covid-19 neuropathy.
- Trial name
- COVID (NCT05911113)
- Testing
- sensory re-education training, traditional treatment
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Urinary Tract Infections, Urinary Catheterization
Ureteral Stent Exchange Abstention in Urinary Tract Infections
The Committee of Infectiology of the French Association of Urology (CIAFU) provided, for the first time in 2020, comprehensive guidelines for ureteral stent-associated urinary tract infections (USAUTI) prevention, diagnosis and…
- Trial name
- JJ-change-UTI (NCT06503588)
- Testing
- Guidelines promoting surgical abstention
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Central Hospital, Nancy, France
Anxiety, Depressive Symptoms
Online or In-person Interventions on Anxiety and Depression Symptoms in Caregivers of Patients with Cancer
Oncological diseases are considered a family disease because when one member is diagnosed with cancer, the psycho-physical, social and economic consequences affect the entire family.
- Trial name
- CBT_ONLINE (NCT06592573)
- Testing
- CBT_ONLINE, CBT_IN PERSON
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Fondazione ANT Franco Pannuti ETS
Ventilator Associated Pneumonia, Brain Injuries
M-I/E for Preventing VAP in Post-neurosurgical Patients
Ventilator-associated pneumonia (VAP) is a common infection in critically ill patients, especially those with acute brain injuries, leading to increased mortality and longer ICU stays.
- Conditions
- Ventilator Associated Pneumonia, Brain Injuries, Mechanical Insufflation-exsufflation
- Trial name
- NCT06511986
- Where
- China
- Volunteers
- 210 people
- Sponsor
- Beijing Sanbo Brain Hospital
Mental Health Disorder, Mental Disorder
Impact of Psychological Therapies on Emergency Medical Patients
Prevalence of anxiety and depression in the general population is known, but is under researched in the acute hospital setting and there is little evidence on the prevalence of anxiety and depression within the emergency medical…
- Conditions
- Mental Health Disorder, Mental Disorder, Mental Health Wellness 1
- Trial name
- NCT05303870
- Testing
- Improving access to psychological therapies (IAPT)
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- East Suffolk and North Essex NHS Foundation Trust
Chronic Obstructive Pulmonary Disease
Randomized Controlled Study to Investigate the Impact of Different Intensities Training on ADL and BODE Index in COPD
The local and systemic manifestations that affect patients with Chronic Obstructive Pulmonary Disease (COPD) cause severe dyspnoea and limitation of functional capacity, leading to impairment in the performance of activities of…
- Trial name
- NCT01977469
- Testing
- Low intensity resistance training, High intensity resistance training, Aerobic training
- Where
- Brazil
- Volunteers
- 45 people
- Sponsor
- Universidade Federal de Sao Carlos
Obstructive Sleep Apnea
The Impact of Fluid Volume Shifts on Upper Airway Collapse and Obstructive Sleep Apnea in Surgical Patients
The objective of this study is to examine the contribution of intravenous (IV) fluid administration and rostral fluid shift from the legs to the neck thereby leading to worsening of sleep apnea following surgery.
- Trial name
- NCT03850041
- Where
- 2 sites in Canada
- Volunteers
- 50 people
- Sponsor
- University Health Network, Toronto
Sleep Apnea, Obstructive, Acute Myocardial Infarction
The Impact of Obstructive Sleep Apnea on the Outcomes in Patients of First-Time Acute Myocardial Infarction
Objective: Untreated OSA is associated with three fold risk of fetal and non-fetal cardiovascular events than control subjects in the long-term follow up.
- Trial name
- NCT00854997
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- National Taiwan University Hospital
COVID-19, Stress Disorders, Post-Traumatic
Psychological Impact of Medical Evacuations on Families of Patients Admitted to Intensive Care Unit for Severe COVID-19
At the "Métropole Savoie" hospital, to deal with the daily influx of severe patients during the second wave of COVID-19, 23 patients had to be transferred away from their home city and far from their families as part of a medical…
- Trial name
- IPES-CoV (NCT05421182)
- Testing
- Revised Impact of Event Scale, Hospital Anxiety and Depression scale, 36-Item Short Form Survey
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Metropole Savoie
Dental Anxiety, Impacted Mandibular Third Molar
Effects of Virtual Reality Content on Anxiety During Third Molar Surgery
This randomized controlled study evaluated whether the content of an immersive virtual reality environment influenced anxiety in adults undergoing surgical removal of an impacted mandibular third molar.
- Trial name
- NCT07819123
- Testing
- Nature-Based Virtual Reality, Art-Gallery Virtual Reality
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Recep Tayyip Erdogan University
Edentulism
The Impact of Palatal Rugae Addition to Complete Dentures on Patients' Satisfaction and Oral Health Related Quality of Life
In conventional maxillary complete dentures, the palatal surface is typically smooth and polished, lacking the natural anatomy of the palatal rugae.
- Trial name
- Palatal rugae (NCT07034079)
- Testing
- complete dentures
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Type 2 Diabetes, Type 2 Diabetes Treated With Insulin
Anxiety Reduction in Type 2 Diabetes Through Breathing ExercisesPatients With Type 2 Diabetes
Injection-related anxiety is a significant barrier to the management of type 2 diabetes, adversely affecting treatment adherence and glycemic control.
- Trial name
- NCT06519903
- Testing
- BREATH technique
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people
- Sponsor
- Goztepe Prof Dr Suleyman Yalcın City Hospital
Obesity
INSPIRE Turkey :A Research Study Looking at the Clinical Parameters Associated With Use and Discontinuation of Saxenda® in Local Clinical Practice in Turkey by Analysing Past Patient Medical Records
The study is investigating the use of Saxenda (liragltuide 3.0 milligrams (mg) once daily) for weight management. The primary objective is to investigate the change in body weight after initiation and use of Saxenda ® according…
- Trial name
- INSPIRE Turkey (NCT05438186)
- Testing
- Liraglutide
- Where
- Turkey (Türkiye)
- Sponsor
- Novo Nordisk A/S
Bleeding Reduction
Low vs. Very Low Dose of Prophylactic Tranexamic Acid for Bleeding Reduction During Rhinoplasty
The purpose of this study is to determine whether very low dose of preoperative tranexamic acid (5mg/kg) is as effective as low dose (10mg/kg) for intraoperational bleeding reduction in patients undergoing elective rhinoplasty…
- Trial name
- NCT03070847
- Testing
- Tranexamic Acid, Sodium Chloride
- Where
- Poland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Bartłomiej Wódarski
Mitral Insufficiency
Assessing the Relationship Between Symptoms and Mitral Regurgitnant. Severity
The current American College of Cardiology/American Heart Association (ACC/AHA) guidelines recommend surgery in patient with mitral regurgitation (MR) based on 1) the severity of MR and 2) the presence or absence of symptoms.
- Trial name
- NCT06738615
- Testing
- Pressure volume loop evaluation, cardiovascular magnetic resonance imaging, Cardiopulmonary exercise testing (CPET)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Atlantic Health System
NSCLC, Non Small Cell Lung Cancer
Impact of Concomitant Use of Steroids and Immune-Checkpoint Inhibitors on Survival Outcomes in NSCLC Patients
The goal of this observational study is to assess the effects of systemic corticosteroid use during immune checkpoint inhibitor (ICI) therapy in patients with non-small cell lung cancer (NSCLC).
- Trial name
- NCT06751108
- Testing
- Corticosteroids (CS), Immune Checkpoint Inhibitors
- Where
- South Korea
- Volunteers
- 2,000 people
- Sponsor
- Seoul National University
Disorder of Consciousness
Neurorehabilitation in Patients With Disorders of Consciousness: Multidimensional Ambispective Study on the Impact of Single and Combined Approaches
Disorders of consciousness (DOC), such as the vegetative state/unresponsive wakefulness syndrome (VS/UWS) and the minimally conscious state (MCS), represent severe clinical conditions arising from acquired brain injury (ABI)…
- Trial name
- NCT07385508
- Testing
- Multidisciplinary neurorehabilitation
- Where
- Italy
- Volunteers
- 140 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo