Clinical trials: Impacted Third Molar
Dental Pain
Phase 2 Study of Indomethacin Capsules to Treat Dental Pain
The purpose of this study is to determine whether Indomethacin Test Formulation Capsules are safe and effective for the treatment of dental pain.
- Trial name
- NCT00964431
- Testing
- Celecoxib 400 mg, Indomethacin Test (lower dose), Indomethacin Test (upper dose)
- Where
- United States
- Volunteers
- 203 people
- Sponsor
- Iroko Pharmaceuticals, LLC
Impacted Lower Third Molars Roots
Verification of the Root Form Classification of Impacted Lower Third Molars
A clinical study will be conducted to verify the reliability of the root form classification of impacted lower third molars that was put by Abu-Mostafa N (2023) The root forms of partially or fully impacted lower third molars…
- Trial name
- NCT06044766
- Testing
- Surgical exatrction of impacted lower third molars
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Riyadh Colleges of Dentistry and Pharmacy
Impacted Mandibular Third Molar Extraction, Post Operative Complications
A Comparison of Recovery After Impacted Wisdom Tooth Removal
Justification of the Study There is a high prevalence of impacted third molars, often accompanied by a range of postoperative complications.
- Trial name
- CESE-3M (NCT07304882)
- Testing
- serratiopeptidase, Escin, Conventional drugs
- Where
- Yemen
- Volunteers
- 24 people
- Sponsor
- University of Science and Technology, Yemen
Alveolar Osteitis
NBF Gingival Gel Application After Impacted Lower Third Molar Surgery
Background: Alveolar osteitis is one of the most frequent complications after lower third molar extraction, and is usually accompanied by inflammation, pain and poor wound healing.
- Trial name
- NCT03641482
- Testing
- NBF
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Impacted Mandibular Third Molar
Efficacy of Er:YAG Laser in Removing Impacted Mandibular Third Molars
This randomized controlled clinical trial aims to evaluate the efficacy of the Er:YAG laser in the removal of impacted mandibular third molars compared to the conventional surgical technique.
- Trial name
- NCT07297043
- Testing
- Er:YAG laser, Conventional Rotary Instruments Surgery
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Alexandria University
Pain, Edema
Leukocyte- and Platelet Rich Fibrin (L-PRF) Application in Impacted Mandibular Third Molar Removal Surgery
The purpose of this study was to evaluate the influence of leukocyte- and platelet-rich fibrin (L-PRF) on impacted mandibular third molar (IMTM) extraction wound healing, patient postoperative discomfort, and incidence of…
- Conditions
- Pain, Edema, Wound Heal
- Trial name
- NCT03357484
- Testing
- Leukocyte- and platelet rich fibrin, Blood clot
- Where
- Lithuania
- Volunteers
- 30 people
- Sponsor
- Lithuanian University of Health Sciences
Dental Pain
Evaluation of the Efficacy and Safety of Diclofenac HPBCD 75mg/ml in Treatment of Pain Following Dental Surgery
The present study is aimed at demonstrating the therapeutic equivalence of diclofenac HPBCD 75mg/1ml s.c. with the marketed reference product, Voltarol® 75mg/3ml i.m.
- Trial name
- NCT00943098
- Testing
- Diclofenac HPBCD s.c. 75mg/ml, Voltarol 75mg/3ml i.m.
- Where
- 3 sites in United Kingdom
- Volunteers
- 142 people
- Sponsor
- IBSA Institut Biochimique SA
Impacted Lower Third Molar
Antibiotic Therapy in Impacted Mandibular Third Molar Surgery
This study compared three antibiotic approaches in healthy young adults undergoing surgical removal of impacted lower wisdom teeth: a single dose of antibiotics before surgery, antibiotic treatment after surgery, and no…
- Trial name
- NCT07817940
- Testing
- Amoxicillin-Clavulanate 875 Mg-125 Mg Oral Tablet
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Complications of Extraction of Impacted Teeth
Effect of LLLT and Ozone to Reduce Complications After Extraction of Impacted Lower Molar
Many factors cause third molars to stay impacted in the jaws, hence the extraction of impacted wisdom teeth occurs often in dental clinics.
- Trial name
- NCT05922150
- Testing
- low level laser therapy, ozone gel
- Where
- Iraq
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Operation Site Inflammation, Pain, Postoperative
Efficacy of Ibuprofen Chronotherapy in Healing After Surgical Extraction of the Mandibular Third Molar
Clinical and preclinical studies have demonstrated encouraging results of non-steroidal anti-inflammatory drug (NSAID) chronotherapy in the management and treatment of inflammatory diseases such as rheumatoid arthritis.
- Conditions
- Operation Site Inflammation, Pain, Postoperative, Teeth, Impacted
- Trial name
- NCT03789058
- Testing
- Ibuprofen 400 mg
- Where
- Jordan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Impacted Third Molar Tooth, Impacted Tooth
Comparing OHRQoL: One or Two Sessions for Wisdom Teeth Removal
This single-center prospective cohort study includes patients aged 18-30 years aimed to compare the effects of bilateral extraction of wisdom teeth at a single appointment (Group A) versus two separate appointments (Group B) on…
- Trial name
- NCT05820867
- Testing
- Single-Session Bilateral Mandibular Third Molar Extraction, Two-Session Bilateral Mandibular Third Molar Extraction
- Where
- Turkey (Türkiye)
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Marmara University
Pain, Edema
Evaluation of Two Pharmacological Protocols for Pre-emptive Analgesia in Impacted Third Molar Surgery
The main aim of the study is to investigate the pre-emptive effect of dexamethasone and diclofenac associated to codeine to prevent the pain, edema and limited mouth opening at the extraction of third molar.
- Conditions
- Pain, Edema, Trismus
- Trial name
- NCT02665533
- Testing
- Dexamethasone, Diclofenac Sodium associated with Codeine
- Where
- Brazil
- Volunteers
- 18 people
- Sponsor
- Federal University of the Valleys of Jequitinhonha and Mucuri
Bone Loss, Regenerative Inflammation
Osteogenic Action of a Medical Device Based on Beta-tricalcium Phosphate (BTCP)
The general objective of this split-mouth study is to analyze the osteogenic action of BTCP during the bone regeneration process following the extraction of impacted mandibular third molars.
- Conditions
- Bone Loss, Regenerative Inflammation, Third Molars Extraction
- Trial name
- BTCP (NCT06935747)
- Testing
- Medical device: beta-tricalcium phosphate, Bovine Hydroxyapatite
- Where
- 2 sites in Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mario Pérez Sayáns
Dental Anxiety, Dental Fear
The Effect of Conscious Sedation on Acute Stress
The specific aims of the present study were to evaluate sAA responses to impacted third molar extractions at different time points in the patients under conscious sedation with local anesthesia and to examine the relationship…
- Conditions
- Dental Anxiety, Dental Fear, Tooth Extraction Status Nos
- Trial name
- NCT04207515
- Testing
- Procedures of wisdom tooth removal surgery under conscious sedation, Procedures of wisdom tooth removal surgery under local anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Beykent
Impacted Third Molar Tooth
Topical Hydrocortisone for Pain and Edema Control After Third Molar Surgery
The investigators set out to develop a clinical trial in order to test the topical use of hydrocortisone as a intraoperative irrigant solution.
- Trial name
- NCT03179813
- Testing
- Hydrocortisone, Control
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Impacted Third Molar Tooth
Investigation of the Effects of H-PRF on the Period After Impacted Third Molar Tooth Extraction
After wisdom teeth are extracted, the patient may have some complaints in the post-operative period. Pain, swelling and edema are some of them.
- Trial name
- NCT06244797
- Testing
- L-PRF and H-PRF, Impacted Tooth Removal
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- esengul sen
Impacted Wisdom Tooth, Pain
Investigation of Effectiveness of Local Antibiotic With Platelet Rich Fibrin on Third Molar Surgery Outcomes In Vivo
The aim of this study was investigate the effectiveness of Local Antibiotic Applications With Platelet Rich Fibrin on Third Molar Surgery Outcomes In Vivo and In Vitro.
- Conditions
- Impacted Wisdom Tooth, Pain, Staphylococcus Aureus
- Trial name
- NCT05678296
- Testing
- Diagnosis, Analgesic, traditional osteotomies
- Where
- Cyprus
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ceren Melahat Donmezer
Impacted Third Molar Tooth
Comparison of the Use of Dexamethasone and Diclofenac Sodium in Immediate Post-Operative Care in Third Molar Surgery
The investigators will select 30 patients with symmetrical impaction of third molars, according to Pell and Gregory dental impaction classification, who would be submitted to two surgical procedures, right and left, and in both…
- Trial name
- NCT02698306
- Testing
- Dexamethasone, Diclofenac Sodium
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hospital Geral de Vila Penteado
Impacted Wisdom Teeth
Evaluation of the Effect of Watching Surgery Videos on Social Media on Anxiety Before Impacted Wisdom Tooth Extraction
Surgical extraction of impacted wisdom teeth creates a high level of anxiety on patients. Anxiety in patients can affect the difficulty of tooth extraction, prolong the duration of surgery and increase post-operative pain.
- Trial name
- NCT05890040
- Testing
- questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Tooth Diseases, Piezoelectric Technique
A New Piezoelectric Technique in Third Molar Surgery
The present study aims to analyze the effect of the piezoelectric technique in third molar surgery in terms of facial swelling, trismus and pain in a split-mouth randomized controlled clinical trial
- Conditions
- Tooth Diseases, Piezoelectric Technique, Tooth, Impacted, Tooth Extraction Status Nos
- Trial name
- NCT06212232
- Testing
- Piezoelectric surgery
- Where
- Italy
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Amerigo Giudice