Clinical trials: Impacted Third Molar
Impacted Third Molar Tooth, Impacted Tooth
Comparing OHRQoL: One or Two Sessions for Wisdom Teeth Removal
This single-center prospective cohort study includes patients aged 18-30 years aimed to compare the effects of bilateral extraction of wisdom teeth at a single appointment (Group A) versus two separate appointments (Group B) on…
- Trial name
- NCT05820867
- Testing
- Single-Session Bilateral Mandibular Third Molar Extraction, Two-Session Bilateral Mandibular Third Molar Extraction
- Where
- Turkey (Türkiye)
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Marmara University
Postoperative Pain, Trismus
Effect of CGF on Short Term Clinical Outcomes After Partially Impacted Mandibular Third Molar Surgery
The aim of this study was to evaluate the effectiveness of concentrated growth factor (CGF) on soft tissue healing and postoperative side effects following third molar surgery.
- Conditions
- Postoperative Pain, Trismus, Edema
- Trial name
- CGF (NCT03913884)
- Testing
- Concentrated growth factor, Non-Concentrated growth factor Group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ege University
Impacted Wisdom Teeth
Evaluation of the Effect of Watching Surgery Videos on Social Media on Anxiety Before Impacted Wisdom Tooth Extraction
Surgical extraction of impacted wisdom teeth creates a high level of anxiety on patients. Anxiety in patients can affect the difficulty of tooth extraction, prolong the duration of surgery and increase post-operative pain.
- Trial name
- NCT05890040
- Testing
- questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Impacted Mandibular Third Molar Extraction, Impacted Lower Third Molar
Comparison of PRF and Corticosteroids in Impacted Third Molar Surgery
This prospective, randomized interventional study aims to compare the postoperative effects of standard treatment (control), platelet-rich fibrin (PRF), and PRF combined with corticosteroid treatment in patients undergoing…
- Conditions
- Impacted Mandibular Third Molar Extraction, Impacted Lower Third Molar, Impacted Wisdom Tooth
- Trial name
- NCT07742826
- Testing
- Platelet-rich fibrin (PRF), Dexamethasone, Amoxicillin/Clavulanic Acid
- Where
- Cyprus
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Final International University
Impacted Wisdom Tooth
Comparison The Postoperative Effects of Local and Systemic Antibiotics Applied With Platelets Rich Fibrin
The aim of this study was investigate the comparison of postoperative effects of local antibiotics mixed with platelet-rich fibrin and postoperative systemic antibiotic applications prescribed for mandibular impacted third molar…
- Trial name
- NCT04989127
- Testing
- Diagnosis, traditional osteotomies, Platelet Rich Fibrin
- Where
- Cyprus
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ceren Melahat Donmezer
Impacted Mandibular Third Molar Extraction, Post Operative Complications
A Comparison of Recovery After Impacted Wisdom Tooth Removal
Justification of the Study There is a high prevalence of impacted third molars, often accompanied by a range of postoperative complications.
- Trial name
- CESE-3M (NCT07304882)
- Testing
- serratiopeptidase, Escin, Conventional drugs
- Where
- Yemen
- Volunteers
- 24 people
- Sponsor
- University of Science and Technology, Yemen
Impacted Third Molar Tooth
Post-Surgical Morbidity and Bone Healing of Impacted Lower Third Molars: Piezosurgery vs. Conventional Instruments
The aim of this study is to compare piezosurgery and conventional surgery in impacted third molar surgery and to determine its effect on postoperative outcomes and quality of life.
- Trial name
- NCT06262841
- Testing
- Piezosurgery, Conventional burs
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Ankara University
Bone Loss, Regenerative Inflammation
Osteogenic Action of a Biphasic Bioceramic With Statin in a Third Molar Extraction Model
The clinical study aims to assess the osteogenic effects of Galibone+ in bone regeneration post-extraction of impacted mandibular third molars.
- Trial name
- Galibone (NCT06338241)
- Testing
- Biphasic bioceramic of tricalcium phosphate and hydroxyapatite with simvastatin, Bovine Hydroxyapatite
- Where
- 2 sites in Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mario Pérez Sayáns
Molar, Fourth, Extracting Own Teeth
Effects of the Application of a Hyper-oxygenated Gel After Oral Surgery
The goal of this clinical trial is to evaluate whether the topical application of Novox® Drop on surgical wounds after the extraction of lower third molars can have a clinical advantage.
- Conditions
- Molar, Fourth, Extracting Own Teeth, Edema Face, Pain
- Trial name
- NCT06458478
- Testing
- Hyper-oxygenated gel, glycerin based gel
- Where
- Italy
- Volunteers
- 72 people
- Sponsor
- Azienda Ospedaliera di Perugia
Acute Pain
Nefopam/Paracetamol Fixed Dose Combination in Acute Pain After Impacted Third Molar Extraction
This study aims to evaluate the analgesic efficacy of single and multiple doses of a new fixed dose combination of nefopam hydrochloride 30 mg and paracetamol 500mg taken orally in comparison to each single component.
- Trial name
- NCT04622735
- Testing
- nefopam hydrochloride 30mg / paracetamol 500mg X2, Paracetamol 500 Mg Oral Tablet X2, Nefopam HCl 30 MG Oral Tablet X2
- Where
- 19 sites in Belgium, France and 3 more
- Volunteers
- 321 people
- Sponsor
- Unither Pharmaceuticals, France
Impacted Mandibular Third Molar, Pain
Ultrasonic vs Rotary Instruments in Impacted Mandibular Third Molar Surgery: Clinical and Salivary CRP Outcomes
In the surgical removal of impacted mandibular third molars, ultrasonic surgical devices (piezosurgery) have been introduced with the expectation of reducing postoperative complications such as swelling, pain, and trismus…
- Conditions
- Impacted Mandibular Third Molar, Pain, Swelling, Trismus
- Trial name
- PiezoCRP (NCT07196904)
- Testing
- Ultrasonic Device (Piezosurgery), Conventional rotary instruments
- Where
- Vietnam
- Volunteers
- 22 people
- Sponsor
- Le Huynh Thien An
Teeth, Impacted, Tooth-loss
The Influence of Sedation and General Anesthesia to Patients' Psycho-emotional State Undergoing Wisdom Teeth Extraction
The aim of the study is to evaluate, wheather the sedation or general anesthesia in third molar extractions influence the patient's psycho-emotional status.
- Conditions
- Teeth, Impacted, Tooth-loss, Anxiety, Fear
- Trial name
- NCT04259463
- Testing
- Third molars extraction
- Where
- Lithuania
- Volunteers
- 53 people
- Sponsor
- Inesa Astramskaitė
Dental Anxiety, Impacted Third Molar Tooth
Three Anxiolytic Drugs Used in Third Molar Surgery
This study was to compare the effectiveness of three drugs (Passiflora incarnata, Erythrina mulungum, Midazolam) in controlling anxiety in patients undergoing bilateral extraction of asymptomatic, impacted mandibular third molars.
- Trial name
- NCT02065843
- Testing
- Mulungu, Passiflora incarnata, midazolam
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Sergipe
Impacted Third Molar Tooth
Accuracy of Variables for Impacted Mandibular Third Molar Surgery
Accuracy of the variables used in Wharfe assessment and Pederson difficulty index for impacted mandibular third molar surgery. The lower 3rd molar tooth is one of the most frequently impacted teeth.
- Trial name
- NCT05143359
- Testing
- Wharfe and Pederson difficulty index, Winters difficulty index
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Pain, Teeth, Impacted
Evaluation of Articaine 4% Versus Mepivacaine 2% for Surgery of Molars Thirds: Clinical Trial.
The extraction of third molars, a frequent treatment in clinical dental practice, can lead patients to painful symptoms during and after surgery.
- Trial name
- NCT03384160
- Testing
- Group 1 -Pain monitor, Group 2 -Pain monitor
- Where
- Brazil
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Tooth, Impacted, Tooth Diseases
Ibuprofen Liquid Capsules 2 x 200 mg Efficacy and PK/PD Study in Surgical Removal of Impacted Third Molars
This is a single centre, three-arm randomised, double-blind, double-dummy, parallel group, single-dose, active and placebo-controlled efficacy and pharmacokinetics/ pharmacodynamics study to evaluate the efficacy and safety of 2…
- Conditions
- Tooth, Impacted, Tooth Diseases, Stomatognathic Diseases
- Trial name
- NCT05484401
- Testing
- Ibuprofen 200Mg Oral Cap, Ibuprofen 200Mg Oral Tablet
- Where
- United States
- Volunteers
- 294 people
- Sponsor
- Reckitt Benckiser Healthcare (UK) Limited
Molar, Impacted Teeth
Analgesic Effects of Extraoral Ultrasound Block of Mandibular Nerve for the Extraction of Lower Third Molars
This is a study about the dynamics and effects of different types of blocks (intraoral conduction anesthesia of the alveolar nerve and extraoral US block of the mandibular nerve) for extraction of lower third molars.
- Trial name
- NCT06009302
- Testing
- US guided block of mandibular nerve, Intraoral block of lower alveolar nerve
- Where
- Croatia
- Volunteers
- 36 people
- Sponsor
- Varazdin General Hospital
Tooth Impaction | {Tooth} | Dental, Corticosteroid
Comparison of the Effects of Protocols Applied After Surgical Extraction of Impacted Mandibular Third Molars
Following the surgical extraction of the most commonly impacted mandibular third molars, the first group was planned to receive methylprednisolone, the second group hyaluronic acid, the third group ozone therapy, the fourth group…
- Conditions
- Tooth Impaction | {Tooth} | Dental, Corticosteroid, Hyaluronic Acid, Ozone
- Trial name
- NCT06900907
- Testing
- Diode laser, Hyaluronic acid, Ozone
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Batman University
Third Molar Surgery
Is Therapeutic Elastic Bandage As Effective As Corticosteroids Following Third Molar Surgery?
In this study; Among the patients randomized because of severe postoperative sequelae expected as a result of radiological and clinical examinations; nonsteroid antiinflammatory drug prescribed group compared with preoperative…
- Trial name
- NCT04200885
- Testing
- Dexketoprofen Trometamol, Dexamethasone 21-Phosphate, Therapeutic Elastic Bandage
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Periodontal Defect
Effect of Collagen Membranes on Distal Periodontal Healing of Second Molars After Impacted Mandibular Third Molar Surgery.
Impacted mandibular third molars can cause various complications to the adjacent second molars, such as dental caries, periodontitis, or root resorption. These complications often progress silently and asymptomatically.
- Trial name
- NCT07114523
- Testing
- collagen membrane, third molar surgery
- Where
- Vietnam
- Volunteers
- 20 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City