Clinical trials: Impaired Social Functioning
Mental Health (Depression), Mental Health and General Well-being
Thrive at Home: A Virtual Reality Social Intervention for Older Adults
The goal of this clinical trial is to evaluate whether a virtual reality (VR) based social platform can improve mental health and social connection for older adults who receive in-home care.
- Conditions
- Mental Health (Depression), Mental Health and General Well-being, Loneliness, Well Being
- Trial name
- Thrive at Home (NCT07835568)
- Testing
- Full Virtual Reality Social Intervention, Abbreviated Virtual Reality Social Intervention
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of California, Santa Barbara
Existential Suffering, Meaning of Life
Reminiscence-Based Life Review on Copying With Existential Suffering Among Older Cancer Survivors
Target Issue: Cognitive impairment in older cancer survivors is highly prevalent and the co-existing neuro-psychiatric symptoms, particularly depression, would further complicate the psychosocial consequence of existential…
- Conditions
- Existential Suffering, Meaning of Life, Cognitive Function, Psychological Distress
- Trial name
- NCT05525299
- Testing
- Reminiscence-Based Life Review
- Where
- Hong Kong
- Volunteers
- 116 people
- Sponsor
- The University of Hong Kong
Mild Cognitive Impairment
A Scalable Model for Promoting Functioning and Well-Being Among Older Adults With Mild Cognitive Impairment Via Meaningful Social Interactions: Project SPEAK!
The goal of this study is to refine and test a strategy for engaging older adults with symptoms of SCD/MCI (subjective cognitive decline/mild cognitive impairment) as volunteers to help English language learners (ELLs) who live…
- Trial name
- NCT04717479
- Testing
- Intervention (videoconferencing)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Attention Impaired, Risk-Taking
Effect of Air Pollution on the Cognitive Function of Adolescents
Previous observational studies have reported an association between higher air pollution exposure and lower attention in children.
- Conditions
- Attention Impaired, Risk-Taking, Risk Behavior, Social Preferences
- Trial name
- ATENC!Ó (NCT03762239)
- Testing
- Purifying the air with a Pure Airbox device (Zonair 3D)
- Where
- Spain
- Volunteers
- 2,123 people, healthy volunteers welcome
- Sponsor
- Barcelona Institute for Global Health
Adverse Childhood Experience, Endothelial Function (FMD)
Probing the Role of Mitochondrial Oxidative Stress in Impaired Vascular Function Among Young Adults With Early Life Adversity
Adverse childhood experiences (ACEs) represent highly stressful events in the first 18 years of life that include abuse, neglect, and household and community-level dysfunction.
- Conditions
- Adverse Childhood Experience, Endothelial Function (FMD), Endothelial Injury, Mitochondrial Function
- Trial name
- PROMISE (NCT07244809)
- Testing
- Mitoquinone mesylate (MitoQ)
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Social Anhedonia, Social Function Impairment
Clinical and Neurocomputational Effects of Behavioral Activation in Veterans With Impaired Social Functioning
Poor psychosocial functioning, including social disconnection, is common and disabling among Veterans, and often fails to improve following the best available evidence-based treatments, particularly if more severe pathology is…
- Trial name
- NCT07697001
- Testing
- Behavioral Activation (BA), Supportive Care Therapy (SCT)
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- VA Office of Research and Development
Autism Spectrum Disorder, Autism Spectrum Disorder (ASD)
Intranasal Insulin for Autism Spectrum Disorder in Children and Young Adults Aged 4 to 21 Years
This observational study evaluates the real-world use of intranasal insulin in children and young adults with autism spectrum disorder (ASD) utilizing the ViaNase™ device developed by Kurve Therapeutics.
- Conditions
- Autism Spectrum Disorder, Autism Spectrum Disorder (ASD), Autism Spectrum Disorder High-Functioning, Autism Spectrum Disorder With Absence of Functional Language
- Trial name
- IN-INS-AUT (NCT07521371)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Healing Hope International
Physical Functional Impairment, Cognitive Impairment
PICS-p Longitudinal Cohort Study
Children who survive critical illness may develop new or worsening problems with physical health, cognitive status, emotional well-being, and social functioning.
- Conditions
- Physical Functional Impairment, Cognitive Impairment, Psychological Distress, Impaired Social Functioning
- Trial name
- PICSpLCS (NCT07876271)
- Volunteers
- 200 people
- Sponsor
- Children's Hospital of Fudan University
Mild Cognitive Impairment (MCI)
Sensory Integration Training for Older Adults With Mild Cognitive Impairment
This study aims to investigate the effects of sensory integration training on cognitive functions, quality of life, and social participation in older adults with Mild Cognitive Impairment (MCI)
- Trial name
- NCT07466615
- Testing
- Aerobic Exercise, Sensory Integration Training
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Akdeniz University
Mild Cognitive Impairment (MCI)
Mild Cognitive Impairment and Psychopathology
Mild Cognitive Impairment (MCI) is a condition characterized by cognitive deterioration greater than what is expected from normal aging, representing an important risk factor for the development of dementia.
- Trial name
- MIND (NCT07358962)
- Where
- Italy
- Volunteers
- 118 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Social Isolation, SCD
The Effects of Social Isolation and Social Interaction on the Risk of Dementia Progression and Brain Function in SCD (Subjective Cognitive Decline, SCD)
The goal of this clinical trial is to learn about the effects of social isolation and social interaction on the risk of dementia progression and brain function in SCD 1.
- Conditions
- Social Isolation, SCD, Subjective Cognitive Decline, MCI
- Trial name
- NCT06335836
- Testing
- social isolation
- Where
- China
- Volunteers
- 209 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Emotional Distress, Functional Impairment
Evaluation of Three School-based Mental Health Preventive Interventions in France
To meet adolescents' needs regarding mental health vulnerability, this study aims to propose and evaluate three original school-based preventive interventions delivered to French 13y-adolescents, with respect to their effects on…
- Conditions
- Emotional Distress, Functional Impairment, Psychosocial Problem, Wellbeing
- Trial name
- NCT06059092
- Testing
- Adapt Module, Engage Module, Interact Module
- Where
- 2 sites in France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Nimes
Children and Adolescents With Neuromotor Impairment
A Story for Pepper & Nao
The aim of the present study is to improve cognitive processes that are frequently impaired in children characterised by neuromotor impairment, such as the skills of visual-perceptual analysis and selective attention, working…
- Trial name
- LbyT (NCT06797050)
- Testing
- Training in reordering figurative stories with a social robot through the Learning by Teaching approach
- Where
- 3 sites in Italy
- Volunteers
- 80 people
- Sponsor
- IRCCS Fondazione Stella Maris
COVID-19 Pandemic, Depression, Anxiety
Older Adults' Perceptions of the Impact COVID-19 Pandemic
This multicentre study will be conduct in several Portuguese institutions, which provide care and supporting services for older adults, with aim to assess the impact of COVID-19 pandemic on the cognitive, emotional and social…
- Conditions
- COVID-19 Pandemic, Depression, Anxiety, Cognitive Impairment, Quality of Life
- Trial name
- NCT05379426
- Testing
- Impact COVID-19 pandemic
- Where
- 58 sites in Portugal
- Volunteers
- 880 people
- Sponsor
- Rsocialform - Geriatria, Lda
Cognitive Impairment, Depression, Anxiety
intErnet-based iNterventions FOR Cardiac arrEst suRvivors
This randomized clinical trial will test whether an internet-based lifestyle intervention administered through a web app can foster Health Related Quality of Life in patients who survived an out-of-hospital cardiac arrest and…
- Conditions
- Cognitive Impairment, Depression, Anxiety, Cardiac Arrest, Quality of Life
- Trial name
- ENFORCER (NCT06395558)
- Testing
- Lifestyle intervention
- Where
- 2 sites in Italy
- Volunteers
- 106 people
- Sponsor
- Azienda Usl di Bologna
COPD
COPD and Socially Vulnerable Individuals
The trial investigates and describes the prevalence of COPD in patients who are in the social nurses' target group and investigates the effect of opportunistic screening for COPD in these vulnerable patients.
- Trial name
- NCT04754308
- Testing
- Spirometry
- Where
- 10 sites in Denmark
- Volunteers
- 513 people
- Sponsor
- Hvidovre University Hospital
Persistent Depressive Disorder
Behavioral Activation (BA) for Medication-responsive Chronically Depressed Patients With Impaired Social Functioning
The investigators aimed to assess the ability of a modified version of Behavioral Activation for occupational and social improvement to produce change in: 1. social adjustment, 2. work functioning, 3. avoidance behavior and 4.
- Trial name
- NCT01783080
- Testing
- Behavioral Activation for return to work
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- New York State Psychiatric Institute
Cognitive Impairment, Child Autism
Exercise and Cognition in Children With ASD
Physical exercise is widely reported to be beneficial to executive functions (EFs) in children with autism spectrum disorder (ASD).
- Trial name
- NCT05503459
- Testing
- Bicycle learning, Stationary cycling
- Where
- Hong Kong
- Volunteers
- 82 people
- Sponsor
- Education University of Hong Kong
Schizophrenia
Compensatory Strategies Applied to Cognitive Impairment in Schizophrenia
The purpose of this study is to determine whether Cognitive Adaptation Training are effective in comparison with conventional treatment, focusing on social functions, symptoms, relapse, re-hospitalisation, and quality of life in…
- Trial name
- CAT-Denmark (NCT01055509)
- Testing
- Cognitive Adaptation Training
- Where
- 3 sites in Denmark
- Volunteers
- 65 people
- Sponsor
- University of Southern Denmark
Hearing Loss, Stress
Clinical Trial of the "Living Well With Hearing Loss Workshop"
This study evaluates whether a 2 hour group session, "The Living Well with Hearing Loss Workshop," can successfully teach hard of hearing people how to best use hearing aids and a variety of personal skills to compensate for the…
- Trial name
- NCT00323427
- Testing
- The Living Well with Hearing Loss Workshop, hearing aid services
- Where
- 2 sites in United States
- Volunteers
- 135 people
- Sponsor
- US Department of Veterans Affairs