Clinical trials: Impairment Upper Limb
Stroke
Influence of Handedness on Upper Limb Recovery
This prospective, single-center observational study evaluates whether handedness is associated with upper-limb motor recovery after a recent unilateral stroke.
- Trial name
- HANDISTROKE (NCT07357181)
- Testing
- evaluation
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Stroke
Motor Recovery of the Severely Impaired Paretic Upper Limb After Mirror Therapy in Sub-acute Stroke
Our study aims at investigating the effect of intensive mirror therapy on the motor recovery of severely impaired paretic arm at subacute stroke.
- Trial name
- NCT02942875
- Testing
- mirror therapy, control therapy
- Where
- Hong Kong
- Volunteers
- 35 people
- Sponsor
- The Hong Kong Polytechnic University
Cervical Disc Herniation
Sensory and Functional Impairments in Cervical Disc Herniation
The aim of the study was to evaluate the levels of somatosensory perception, pain threshold and kinesiophobia in individuals with SDH, to examine their relationship with upper extremity functional skills and to compare them with…
- Trial name
- NCT07282522
- Testing
- Somatosensory Perception Tests, The Visual Analog Scale, Pain Threshold and Tolerance Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Inonu University
Shoulder Posterior Instability, Shoulder Anterior Instability
Evaluating Upper Limb Movement Precision With AuReha in People With One-Sided Motor Impairment
The clinical investigation is designed as a controlled, two-arm, intra-patient, non-randomized interventional study aimed at assessing the capabilities of the AuReha system in detecting upper limb movement precision in patients…
- Conditions
- Shoulder Posterior Instability, Shoulder Anterior Instability, Shoulder Anterior Latarjet Instability, Adhesive Capsulitis, Shoulder
- Trial name
- NCT07133100
- Testing
- Upper limb rehabilitation wearable device
- Where
- Italy
- Volunteers
- 52 people
- Sponsor
- DigitalRehab
Acute Respiratory Failure, Encephalopathy
Novel Arm Restraint For Critically Ill Patients To Reduce Immobility, Sedation, Agitation and Cognitive Impairment
This study evaluates a novel arm restraint compared with traditional soft wrist restraints in older critically ill patients. The primary outcome is upper extremity mobility measured by actigraphy, and secondary outcomes include…
- Conditions
- Acute Respiratory Failure, Encephalopathy, ARDS, Sepsis
- Trial name
- NCT04067622
- Testing
- Exersides
- Where
- 3 sites in United States
- Volunteers
- 58 people
- Sponsor
- University of Vermont
Neoplasms
Qigong for Breast Cancer Survivors
Objectives: (1) To investigate the effects of Qigong training on upper limb oedema, circulatory status, shoulder flexibility and muscular strength, body balance, and quality of life (QOL) in community-dwelling breast cancer…
- Trial name
- NCT02420249
- Testing
- Qigong training
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- The University of Hong Kong
Diabetic Macular Edema
To Compare Brolucizumab to Aflibercept in Chinese Patients With Visual Impairment Due to Diabetic Macular Edema
The purpose of this study was to evaluate the efficacy and safety of brolucizumab in treatment of Chinese patients with visual impairment due to Diabetic Macular Edema.
- Trial name
- KINGLET (NCT04058067)
- Testing
- Brolucizumab, Aflibercept
- Where
- 24 sites in China
- Volunteers
- 266 people
- Sponsor
- Novartis Pharmaceuticals
Chronic Stroke
CompARing Long terM Outcomes in Chronic Stroke Survivors Across Investigational Assessments Following a Prescribed Upper Extremity Exercise Program
The purpose of the study is to compare assessments of arm function following a standard exercise program in chronic stroke patients.
- Trial name
- NCT05659875
- Testing
- Standard Occupational Therapy Arm Exercise Program
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- The University of Texas Health Science Center, Houston
Type 2 Diabetes Mellitus, Chronic Kidney Disease Stage 3
Safety and Efficacy Study of Sotagliflozin on Glucose Control in Participants With Type 2 Diabetes, Moderate Impairment of Kidney Function, and Inadequate Blood Sugar Control
Primary Objective: To demonstrate the superiority of Sotagliflozin 200 milligrams (mg) and Sotagliflozin 400 mg versus placebo on HbA1c reduction at 26 Weeks in participants with Type 2 diabetes who have inadequate glycemic…
- Trial name
- SOTA-CKD3 (NCT03242252)
- Testing
- Sotagliflozin
- Where
- 170 sites in United States, Argentina and 14 more
- Volunteers
- 787 people
- Sponsor
- Lexicon Pharmaceuticals
COPD, Upper Extremity
Cognitive Impairment and Upper Extremity Performance in COPD
Within the scope of this study, COPD patients will be divided into two groups according to cognitive dysfunction. Pulmonary function test, COPD assessment scale, Mini-Mental State Examination and Montreal Cognitive Assessment…
- Conditions
- COPD, Upper Extremity, Upper Limb Function, Cognitive Impairment
- Trial name
- COPD (NCT05137483)
- Testing
- Functional tests
- Volunteers
- 80 people
- Sponsor
- Izmir Katip Celebi University
Learning Disorders, Specific, Learning Disabilities
Examining the Effect of a Digital Medical Device for Cognitive and Musical Training in Children With Reading Disabilities
The goal of this clinical trial is to assess the effect on reading skills of the digital medical device Poppins Clinical for cognitive and musical training in pediatric participants (ages 7-11) with a specific learning disability…
- Conditions
- Learning Disorders, Specific, Learning Disabilities, Specific Learning Disorder, With Impairment in Reading, Dyslexia
- Trial name
- POPPINS-CE (NCT06596980)
- Testing
- Poppins Clinical
- Where
- France
- Volunteers
- 38 people
- Sponsor
- Poppins
Multiple Sclerosis
Robot-based Rehabilitation of Upper Limb Impairment in Multiple Sclerosis
Robot-assisted therapy has proven effective in the neuromotor rehabilitation of eg stroke survivors. Robots can be programmed to interact with patients by guiding their movements, by monitoring their performance and by…
- Trial name
- MS-ROBOT (NCT02711566)
- Testing
- Physioassistant: Haptic training, Physioassistant: Sensorimotor training
- Volunteers
- 41 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Cervical Radiculopathy, Cervical Radicular Pain
Investigation of the Effects of Interlaminar Epidural Steroid Injection on Upper Extremity Proprioception in Patients With Chronic Cervical Radiculopathy
Cervical radiculopathy is a common condition caused by irritation or compression of cervical nerve roots, often leading to unilateral neuropathic pain and functional impairment.
- Conditions
- Cervical Radiculopathy, Cervical Radicular Pain, Proprioception
- Trial name
- NCT07307846
- Testing
- Interlaminar Epidural Steroid Injection (ILESI)
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Marmara University
Stroke, Arm Weakness as a Consequence of Stroke
Low Intensity Focused Ultrasound Stimulation in Stroke Patients - Parameter Optimization
The goal of this research study is to optimize the parameter of Low-Intensity Focused Ultrasound Stimulation (LIFUS) that is most effective in changing cortical excitability and motor learning skills in patients who suffered a…
- Conditions
- Stroke, Arm Weakness as a Consequence of Stroke, Upper Extremity Hemiparesis, Upper Extremity Impairments
- Trial name
- LIFUS-OPTIMIZE (NCT07220005)
- Testing
- Low intensity focused ultrasound stimulation
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Duke University
Stroke
Evaluation of a Haptic Glove for Assessing Tactile Perception in Post-Stroke Patients
The aim of the SCORES Haptic Glove Study is to assess the technical features, safety, and reliability of a sensor-equipped glove designed to evaluate tactile perception.
- Trial name
- SCORES-glove (NCT06643273)
- Testing
- Robotic rehabilitation, Conventional rehabilitation
- Where
- 3 sites in Italy
- Volunteers
- 126 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Musculoskeletal Pain, Overuse Syndrome
Use Of Orthotics To Reduce Pain In Musicians
This interventional clinical study investigates the effectiveness of applying a forearm strap orthosis in 30 individuals experiencing forearm pain due to playing a musical instrument. Participants used the orthosis for 4 weeks.
- Conditions
- Musculoskeletal Pain, Overuse Syndrome, Tendinopathy, Elbow, Musculoskeletal Pain and Functional Impairment in Musicians
- Trial name
- NCT07274540
- Testing
- Foream Band Orthosis
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Medipol University
Stroke
SaeboGlove Therapy for Severe Upper Limb Disability and Severe Hand Impairment After Stroke
The study will aim to determine whether 6-weeks of using a SaeboGlove independently (with or without help from a carer) improves upper limb function (measured using the Action Research Arm Test score) in comparison to usual care…
- Trial name
- SUSHI (NCT04007315)
- Testing
- SaeboGlove therapy, Usual care
- Where
- 3 sites in United Kingdom
- Volunteers
- 110 people
- Sponsor
- NHS Greater Glasgow and Clyde
Hunter Syndrome
Study of Intrathecal Idursulfase-IT Administered in Conjunction With Elaprase® in Pediatric Patients With Hunter Syndrome and Early Cognitive Impairment
Study HGT-HIT-094 is a multicenter study designed to determine the effect on clinical parameters of neurodevelopmental status of monthly IT administration of idursulfase-IT 10 mg for 12 months in pediatric patients with Hunter…
- Trial name
- AIM-IT (NCT02055118)
- Testing
- idursulfase-IT, No IT treatment
- Where
- 9 sites in United States, Australia and 5 more
- Volunteers
- 58 people
- Sponsor
- Shire
Memory Loss
Efficacy of Cognitive Training in Subjective Memory Impairment
This study evaluates the efficacy of cognitive training in subjects with subjective memory impairment. The first group will receive cognitive training and lifestyle modification in combination, the second group will receive only…
- Trial name
- NCT02555774
- Testing
- cognitive training, lifestyle modification
- Where
- South Korea
- Volunteers
- 65 people
- Sponsor
- Asan Medical Center
Post Traumatic Stress Disorder
MDMA-Assisted Therapy for Veterans With Moderate to Severe Post Traumatic Stress Disorder
This randomized, double-blind, single-site phase II 2-arm study will investigate the safety and preliminary efficacy of MDMA-assisted therapy compared with low dose d-amphetamine-assisted therapy on the severity of PTSD symptoms…
- Trial name
- NCT05790239
- Testing
- 3,4-methylenedioxymethamphetamine, d-amphetamine, Therapy
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Stephen Robert Marder