Clinical trials: Implant Osseointegration
Alveolar Bone Loss
Effect of Topical Melatonin Application on Dental Implant Osseointegration and Marginal Bone Level
Background: Melatonin (N-acetyl-5-methoxy-tryptamine) is an indoleamine synthesized and secreted by the pineal gland and other organs, such as the retina, bone marrow, and intestines in a circadian pattern.
- Trial name
- NCT04229719
- Testing
- N-acetyl-5-methoxytryptamine
- Where
- Iraq
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Guided Bone Regeneration
A Phase I Study of SB Cell for the Enhanced Osseointegration of Guided Bone Regeneration in Implant Surgery
This is a Phase 1 study to evaluate the safety profile of autologous-derived SB cells to enhance osseointegration of GBR in patients undergoing dental implant surgery.
- Trial name
- NCT04451486
- Testing
- SB cells
- Where
- Taiwan
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Bone Density, Low
Comparing the Hydrodynamic Piezoelectric Technique With Osseodensification for the Assessment of Internal Sinus Iift-ing
Successful osseointegration considered the cornerstone in implant stability which predict the highest implants success outcomes.
- Trial name
- RCT (NCT06285903)
- Testing
- internal sinus lift surgery
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Bone Loss, Alveolar, Resorption, Bone
The Effect of Growth Factor on Implant Osseointegration
In this study, concentrated growth factor obtained by centrifuging the patient's own blood and advanced platelet-rich fibrin liquids were applied to the implant cavity and surface.
- Conditions
- Bone Loss, Alveolar, Resorption, Bone, Osseointegration Failure of Dental Implant
- Trial name
- NCT04879446
- Testing
- Concentrated growth factor(CGF), Advanced platelet rich fibrin (A-PRF), Control side of concentrated growth factor study group
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Uğur Can ÜNLÜGENÇ
Osseointegration Failure of Dental Implant, Bone Density Increased
Emdogain Implementation With Transcrestal Sinus Lifting and Dental Implant Placement
The aim of this study is to evaluate the clinical and radiographic results of implants placed using osteotome sinus floor elevation (OSFE) with and without simultaneous enamel matrix derivative (EMD) application.
- Trial name
- NCT05507047
- Testing
- Enamel Matrix Protein
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- T.C. Dumlupınar Üniversitesi
Osseointegration Failure of Dental Implant
Immediate Loading and Fully Guided Surgery: Single Implants
To evaluate the overall treatment outcome of single implants installed with the assistance of fully guided-surgery, submitted to immediate loading with restorations fabricated with the help of intraoral scanning, during a 1-year…
- Trial name
- NCT04061694
- Testing
- Immediate loading, fully guided surgery and 3D printed restoration, Immediate loading
- Where
- Sweden
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Folktandvården Skåne AB
Dental Implant, Osseointegration
Assessment of Early Healing Period of Dental Implants
This prospective cohort study aimed to evaluate, clinically, radiographically, and digitally, the volumetric changes occurring during the early healing period after implant treatment in patients with tooth loss in the posterior…
- Conditions
- Dental Implant, Osseointegration, Biological Width
- Trial name
- NCT06554444
- Testing
- Dental Implant Surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Dental Implantation, Dental Implants
The Application of Root Analogy Implant in Immediate Implantation
The current clinical implant techniques used include immediate implantation, early implantation, and delayed implantation. With the acceleration of the current pace of life, immediate implantation is increasingly favored by…
- Conditions
- Dental Implantation, Dental Implants, Osseointegration
- Trial name
- RAI (NCT06449391)
- Testing
- RAI
- Where
- China
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- The Dental Hospital of Zhejiang University School of Medicine
Atrophic Maxilla, Partial Edentulism
Prospective Study of Bone Augmentation With Lateral Sinus Lift and Osseointegration of Dental Implants
By using a split-mouth model in the maxilla, lateral sinus lift procedures will be performed using xenograft on one side vs autologous bone augmentation and PRF membranes on the other side.
- Trial name
- NCT07014085
- Testing
- "Histomorphometric Evaluation of Bone Augmentation Using Xenografts Versus Autologous Bone Grafts in Dental Implant Patients: A Comparative Clinical Study
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Maria H. Pham
L-PRF, Dental Implants
Evaluation of the Effect of Leucocyte Platelet-Rich Fibrin (L-PRF) Technique Applied in Post-extraction Sockets Before Placement of Dental Implants
Aim of study: The application of L-PRF membrane in post-extraction sockets outmatches the use of a) allograft covered with a collagen fleece b) allograft combined with L-PRF membrane c) natural healing, with reference to bone…
- Conditions
- L-PRF, Dental Implants, Osseointegration, Alveolar Bone Grafting
- Trial name
- NCT07387913
- Testing
- Allograft and collagen membrane, Allograft and L-PRF membrane, L-PRF
- Where
- Greece
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Osseointegration, Osseodensification
Osseodensification and Dental Implant Stability
Osseointegration refers to the formation of a structural and functional bone-to-implant interface, without the interposition of soft tissue. Successful osseointegration will provide long term success for the dental implant.
- Trial name
- NCT05376020
- Testing
- Densah Burs, Conventional Burs
- Where
- Ireland
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Dublin, Trinity College
Dental Implant Stability
Osseointegration With a New Hydrophilic Surface
This study was conducted to compare implant stability of Hiossen ET III implants with its new hydrophilic surface (NH) and Hiossen ET III implants with the SA surface.
- Trial name
- NCT03649100
- Testing
- Implant placement
- Where
- 3 sites in Italy
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Osstem AIC
Implant Geometry, Osseointegration, Soft Tissue Volume, Marginal Bone Levels, Soft Tissue Recession, Volumetric Analysis
The Influence of a New Implant Neck Configuration on Hard and Soft Tissue Healing
Title: Randomized Controlled Clinical Trial comparing two dental implants with different neck configurations. Objective: To evaluate the changes in peri-implant soft tissues and marginal bone level when using a one-piece implant…
- Trial name
- NCT04308083
- Testing
- dental implant placement
- Where
- Spain
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- PerioCentrum Research
Dental Implants
Marginal Bone Level Around Titanium Implants Produced by Additive Manufacture
The aim of this study will be to evaluate the non-inferiority of implants produced by additive manufacture loaded in 30 days when compared with those loaded in 90 days, in relation to marginal bone loss, after 01 (one) year of…
- Trial name
- NCT05627037
- Testing
- Dental implant produced by additive manufacture
- Where
- Brazil
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Vitamin D Deficiency, Osseointegration Failure of Dental Implant
Vitamin-D Insufficiency and Implants
Vitamin D is important for bone health, immune function, and inflammation, along with dental implant success. The study aimed to assess bone markers and cytokine levels in patients with and without vitamin D insufficiency to…
- Conditions
- Vitamin D Deficiency, Osseointegration Failure of Dental Implant, Peri-Implantitis
- Trial name
- NCT06452251
- Testing
- OPG, OC, RANKL, IL-10, IL-1β, Ca, TNF-α and Caspase-1 ELISA, Resonance Frequency Analysis, Periodontal clinical examination
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Vesile Elif Toy
Immediate Dental Implant, Implant Osseointegration
Clinical and Radiographic Evaluation of Topical Vitamin D on Immediate Dental Implants
This study evaluates the clinical and radiographic outcomes of topical vitamin D application on immediate dental implants in patients undergoing single-rooted tooth extraction in the anterior mandibular region.
- Conditions
- Immediate Dental Implant, Implant Osseointegration, Vitamin D, Tooth Extraction
- Trial name
- NCT06806423
- Testing
- Immediate Dental Implant Placement without Adjunctive Treatments, Immediate Dental Implant Placement with Topical Vitamin D Gel Application
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Suez Canal University
Missing Tooth, Osseointegration Failure of Dental Implant
X-space Implants in Post-extraction Sites.
Several recent systematic reviews have highlighted how the macrodesign of dental implants can influence stress distribution and biomechanical and biological behavior in implants immediately inserted in post-extraction sites.
- Trial name
- NCT04492111
- Testing
- post-extraction dental implant
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Bari
Deficiency, Vitamin D
Effect of Vitamin D Replacement on Bone Healing in Mini-dental Implants
1. Title 2. Executive team 3. Research line 4. Summary 5. Research problem 6. Justification 7. Literature review 8. Objectives 9. Materials and methods 10. Dissemination of knowledge generated 11. Schedule of activities 12.
- Trial name
- NCT03356730
- Testing
- Vitamin D
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidade de Passo Fundo
Peri-Implantation Loss, Periodontal Bone Loss
The Rehabilitation of Atrophic Jaws Using Short Implants With Different Surface Characteristics
The aim of the research is to evaluate the clinical outcome of short dental implants, characterized by a new macro-structural design and inserted in the upper or lower jaw in patients with reduced bone volume.
- Conditions
- Peri-Implantation Loss, Periodontal Bone Loss, Periimplantitis, Gingival Inflammation
- Trial name
- NCT05766878
- Testing
- implants placement
- Where
- 3 sites in Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Foggia
Dental Implant
Investigating Implant Surface Effect on Osseointegration: NGA vs. ModSLA
This study aims to characterise the stability of crestal bone levels one year after loading, the associated aesthetic outcomes, immunological response, prosthodontic outcomes as well as overall patient reported outcome measures…
- Trial name
- NCT06086873
- Testing
- Implant Type
- Where
- United Kingdom
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Barts & The London NHS Trust