Clinical trials: Implant Osseointegration
Immediate Implantation of Two-piece Zirconia Dental Implants
Clinical Outcome of Two-piece Zirconia Implants in Immediate Implant Placement
The purpose of the study is to test whether a two-piece zirconia implant is as reliable in the indication of immediate implant placement as a standard titanium implant.
- Trial name
- NCT05369299
- Testing
- Implant Straumann® Pure Ceramic Two Piece Implant, two-piece titanium implant Neoss® ProActive Tapered Implant
- Where
- Austria
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Tooth Loss, Edentulous Jaw
Molecular Content of Peri-implant Sulcus During Wound Healing and Osseointegration Following Drilling and Piezosurgery
This study aims to evaluate the levels of cytokines, chemokines and growth factors in peri-implant sulcular fluid (PISF) during healing and osseointegration at osteotomy sites prepared either with piezosurgery (PS) or drills (D).
- Trial name
- NCT03538184
- Testing
- Piezosurgery, Drill
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Ege University
Jaw, Edentulous, Dental Implant
An Implant With an Acid-etched Fixture Surface and Internal-hex Collar May Achieve Greater Osseointegration.
Brånemark System® dental implant osseointegration was introduced clinically in 1965 as a novel approach to the replacement of missing teeth.
- Trial name
- NCT01641198
- Testing
- Configuration 1, Configuration 2, Configuration 3
- Where
- Canada
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Université de Montréal
Post-osseointegration Biological Failure of Dental Implant, Alveolar Bone Loss
The Influence of Mucosal Tissue Thickness on Soft and Hard Tissue Changes Around Implants
Crestal bone and soft tissue stability around implants is an important issue in implant dentistry. Initial vertical mucosal tissue thickness was shown to be one of the factors having impact on bone stability.
- Trial name
- NCT02580721
- Testing
- Dentsply Astra Tech Implant System EV
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Evaluating the Clinical Efficacy of Applying Ultraviolet Photofunctionalization (UV phF) to Standard Titanium Implants Immediately Before Surgery, Monitoring Early Implant Stability and Osseointegration During the Critical Initial Healing Phase
Clinical Assessment of UV Photofunctionalization on Stability and Osseointegration of Early Loaded Implants
The goal of this clinical trial is to learn if UV light treatment (photo functionalization) works to help dental implants heal faster and become stable enough for early use in adults missing teeth in the lower back jaw.
- Conditions
- Evaluating the Clinical Efficacy of Applying Ultraviolet Photofunctionalization (UV phF) to Standard Titanium Implants Immediately Before Surgery, Monitoring Early Implant Stability and Osseointegration During the Critical Initial Healing Phase, Determining the Feasibility and Success Rate of an Accelerated "Early Loading" Protocol, Assessing the Survival Rate of the Implants, Along With the Peri-implant Soft Tissue Response and Marginal Bone Preservation
- Trial name
- UV (NCT07868744)
- Testing
- UV-photofunctionalized titanium dental implants
- Where
- Egypt
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Jaw, Edentulous
Release of Osteogenic Markers in Immediately and Non-loaded Dental Implants
The aim of this study was to compare the release of the osteoprotegerin (OPG), transforming growth factors (TGF-α), osteocalcin (OCN), osteopontin (OPN), and parathyroid hormone (PTH) during osseointegration of dental implants…
- Trial name
- NCT01909999
- Testing
- Osteogenic markers Evaluation, Clinical parameters evaluation, Implant instalation
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Renato Correa Viana Casarin
Implant Site Reaction
Assessment of Osseointegration Properties of Nano-Hydroxy Apatite Coated Titanium Implant
the purpose of this trial is to evaluate the osseointegration properties of nano-hydroxy apatite coated titanium implants in posterior maxilla.
- Trial name
- NCT05936775
- Testing
- nano-hydroxy apatite coated titanium implants, sandblasted large acid itched coated titanium implant
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- October University for Modern Sciences and Arts
Platelet-Rich Fibrin, Dental Implantation
Influence of Human Platelet Derivatives on Dental Implant
The goal of this randomized controlled trial is to evaluate the benefit of PRF membrane on bone around dental implant in patients who need treatment with dental implant.
- Conditions
- Platelet-Rich Fibrin, Dental Implantation, Bone Substitute
- Trial name
- NCT06044246
- Testing
- PRF membrane
- Where
- Iraq
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Al-Mustansiriyah University
Edentulous Alveolar Ridge
Effect on Allogenic Mesenchymal Stem Cells on Osseointegration of Dental Implants
As Regenerative Medicine is the next level in medicinal sciences, the use of mesenchymal cells have become prevalent, Similarly now stem cells are being used in dental research as well in various clinical applications.This study…
- Trial name
- MSC&IMPLANTS (NCT02731586)
- Testing
- Allogenic Mesenchymal stem cells
- Where
- India
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Sri Sai College of Dental Surgery and Research Centre
Dental Implants, Hyaluronic Acid
Assessment of Rapid Osseointegration of Dental Implants with Different Coatings
The study will assess early osseointegration of dental implant with three different coating materials through secondary implant stability
- Trial name
- NCT06650280
- Testing
- Hyaluronic Acid (HA), nano-hydroxyapatite, sandblasted acid etched
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- October University for Modern Sciences and Arts
Dental Implant
Impact of Biological Factors on Dental Implant
The goal of this randomized controlled trial is to compare the response of different bone densities to treatment with Platelet Rich Fibrin (PRF) in patients who need treatment with dental implant.
- Trial name
- NCT06037070
- Testing
- Platelet Rich Fibrin
- Where
- Iraq
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Al-Mustansiriyah University
Bone Loss, Alveolar, Resorption, Bone
The Effect of Growth Factor on Implant Osseointegration
In this study, concentrated growth factor obtained by centrifuging the patient's own blood and advanced platelet-rich fibrin liquids were applied to the implant cavity and surface.
- Conditions
- Bone Loss, Alveolar, Resorption, Bone, Osseointegration Failure of Dental Implant
- Trial name
- NCT04879446
- Testing
- Concentrated growth factor(CGF), Advanced platelet rich fibrin (A-PRF), Control side of concentrated growth factor study group
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Uğur Can ÜNLÜGENÇ
Tooth Loss, Edentulism
PMCF Study on the Effectiveness and Safety of BIODENTOSS® and DWC® Dental Implants and Superstructures
This prospective, single-center, interventional post-market clinical follow-up (PMCF) study aims to evaluate the early-term (24 months post-implantation) safety and efficacy of CE-marked BIODENTOSS® and DWC ® Dental Implants and…
- Trial name
- NCT07633665
- Testing
- BIODENTOSS Bone-Level Dental Implant and Superstructures, DWC Bone-Level Dental Implant and Superstructures
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Değirmenci Otomotiv ve Metal Endüstri A.Ş.
Tooth Loss in the Anterior Maxilla, Alveolar Bone Loss* / Therapy
Beta-Tricalcium Phosphate Grafting of Peri-implant Jumping Gaps Greater Than 2 mm in Immediate Implants
This randomized controlled trial evaluated whether grafting the peri-implant "jumping gap" with injectable β-tricalcium phosphate (β-TCP) improves outcomes after immediate implant placement in sites where the horizontal gap…
- Trial name
- NCT07709676
- Testing
- Experimental: Test: beta-tricalcium phosphate grafting
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Minia University
Amputation
Magnetic Bead Tracking System and eOPRA Implant System With Bionic Prosthesis for Transtibial Amputees
The e-OPRA Implant System, is a further development of the OPRA (Osseointegrated Prostheses for the Rehabilitation of Amputees) Implant System.
- Trial name
- TTeOPRA+MB (NCT06391697)
- Testing
- eOPRA Implant System for Transtibial Amputees and Magnetic Bead Tracking System
- Where
- 2 sites in United States
- Volunteers
- 7 people
- Sponsor
- Brigham and Women's Hospital
Cold Atmospheric Plasma, Dental Implants
Cold Plasma Effects on Dental Implant Stability
Cold plasma-mediated implant surface activation may reverse the biological aging of titanium by enhancing hydrophilicity and cellular response.
- Trial name
- NCT07348770
- Testing
- Dental implant placement, Dental implant placement and vacuum plasma application, Dental implant placement and argon jet plasma application
- Where
- Turkey (Türkiye)
- Volunteers
- 11 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Dental Implant, Surgical Dental Prostheses
Low Intensity Pulsed Ultrasound Versus Low Level Laser Therapy Post Dental Implant
The purpose of the study is to investigate the significance difference between low intensity pulsed ultrasound (LIPUS) versus low-level laser therapy (LLLT) on osseointegration, soft tissue healing, pain pressure threshold and…
- Conditions
- Dental Implant, Surgical Dental Prostheses, Dental Implantation
- Trial name
- NCT05938868
- Testing
- Low intensity pulsed ultrasound (LIPUS), low level diode laser therapy, Standard Care
- Where
- Egypt
- Volunteers
- 63 people
- Sponsor
- Ahram Canadian University
Dental Implant Placement, Ozone Therapy
Ozone Versus Conventional Socket Disinfection for Primary Dental Implant Stability
This randomized split-mouth controlled clinical trial aims to compare the effects of ozone and conventional implant site disinfection on primary and early secondary implant stability.
- Trial name
- NCT07687680
- Testing
- Ozone Implant Site Disinfection, Conventional Socket Disinfection
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- Zeliha Başak Çakır Erdil
Alveolar Bone Loss, Dental Implant
Magnetic Mallet Vs Conventional Drilling in D4 Posterior Maxilla
The goal of this clinical trial is to evaluate whether the magnetic mallet technique improves primary implant stability and clinical outcomes compared with conventional drilling during dental implant placement in the posterior…
- Conditions
- Alveolar Bone Loss, Dental Implant, Osseodensification Drilling Technique
- Trial name
- NCT07424820
- Testing
- Conventional drilling osteotomy, Magnetic mallet osteotomy
- Where
- Iraq
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Mosul
Prosthesis, Lower Limb Amputation Knee
Clinical and Functional Assessment of Patients With Transfemoral Amputation Treated With Osteointegrated Implant
Limb amputation is a traumatic event that significantly reduces the ability to perform daily activities, impairs mobility, and lowers quality of life.
- Conditions
- Prosthesis, Lower Limb Amputation Knee, Amputation; Traumatic, Leg, Lower
- Trial name
- OSTEO-OUTCOME (NCT06737770)
- Testing
- osseointegrated surgery for transfemoral amputation
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- Istituto Ortopedico Rizzoli