Clinical trials: Implantable Cardiac Defibrillator
Ventricular Arrhythmias
A PRospective, rAndomizEd Comparison of subcuTaneOous and tRansvenous ImplANtable Cardioverter Defibrillator Therapy
This randomized controlled trial will outline the advantages and disadvantages of the subcutaneous implantable cardioverter defibrillator (ICD) compared to the transvenous ICD.
- Trial name
- PRAETORIAN (NCT01296022)
- Testing
- Implantation of subcutaneous ICD, Implantation of transvenous ICD
- Where
- 39 sites in United States, Czechia and 4 more
- Volunteers
- 850 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Arrhythmias, Cardiac
Study to Monitor Patients With Pacemakers or ICDs Who Undergo MRI Scans
This study is a prospective, non-randomized, unblinded case series of patients with permanent pacemakers and implantable cardioverter-defibrillators undergoing medically-required magnetic resonance imaging (MRI) scanning, at St.
- Trial name
- NCT01999751
- Testing
- MRI Scan
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- Essentia Health
Implantable Cardioverter-Defibrillators, Ventricular Fibrillation
Benefits of Implantable Cardioverter Defibrillator Follow-up Using Remote Monitoring
In many aspects of every-day life, modern communication systems bring about a remarkable increase in comfort and safety by transmitting data and information in an easy and reliable manner.
- Conditions
- Implantable Cardioverter-Defibrillators, Ventricular Fibrillation, Tachycardia, Ventricular
- Trial name
- ECOST (NCT00989417)
- Testing
- ACTIVATION of HOME MONITORING
- Where
- France
- Volunteers
- 473 people
- Sponsor
- Biotronik SE & Co. KG
Anxiety, Depression
REmote Web Assisted Care for Heart Failure Patients With Implantable Cardioverter Defibrillators
Aim and Background: Although implantable cardioverter defibrillators (ICD) save lives, many ICD-patients experience psychosocial complications such as anxiety disorders, depression and reduced quality of life after…
- Conditions
- Anxiety, Depression, Quality of Life
- Trial name
- REACH-ICD (NCT01589913)
- Testing
- ICD-Forum
- Where
- 7 sites in Germany
- Volunteers
- 118 people
- Sponsor
- Wuerzburg University Hospital
Heart Failure, Death, Sudden, Cardiac
Sympathetic Nerve Activity and an Implantable Cardioverter Defibrillator in Heart Failure Patients
The aim of this study is to analyze whether the sympathetic tone, measured indirectly and directly by muscle sympathetic nerve activity recording, is elevated in patients with heart failure receiving an appropriate shock from…
- Trial name
- NCT00439790
- Testing
- Microneurography
- Where
- France
- Volunteers
- 109 people
- Sponsor
- University Hospital, Toulouse
Sudden Cardiac Death, Cardiac Arrest
Experience From the Italian S-ICD Registry
The purpose of this registry is to collect data on implant parameters, early, mid and long-term clinical effectiveness of Subcutaneous Implantable Cardioverter Defibrillator (S-ICD) therapies in order to better understand how to…
- Conditions
- Sudden Cardiac Death, Cardiac Arrest, Ventricular Arrythmia, Implantable Cardiac Defibrillator
- Trial name
- ELISIR (NCT04373876)
- Testing
- Subcutaneous Implantable Cardioverter Defibrillator
- Where
- 18 sites in France, Germany and 2 more
- Volunteers
- 500 people
- Sponsor
- Luigi Sacco University Hospital
Heart Failure, Primary Prevention of Sudden Cardiac Death
Cardioverter DefIbriIlator PlacEMent for priMary Prevention of Sudden cArdiac Death in Patients Older Than 70 Years
The primary objective of DILEMMA study is to assess whether the "heart failure optimal therapy alone (HFOT)" strategy is non inferior to the "HFOT+ICD" strategy in terms of overall survival 48 months after randomization, in…
- Conditions
- Heart Failure, Primary Prevention of Sudden Cardiac Death, Implantable Cardioverter Defibrillator
- Trial name
- DILEMMA (NCT05373940)
- Testing
- ICD implantation, No ICD implantation
- Where
- 19 sites in France
- Volunteers
- 730 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Sudden Cardiac Death
Dilated Cardiomyopathy - Unknown Therapeutic Risk Reduction by Contempary Medication and Implantable Cardioverter-Defibrillators (DUTCH-ICD)
Research questions: The value of primary prevention implantable cardioverter-defibrillator implantation (ICD) therapy in patients with non-ischemic cardiomyopathy (NICM) is under debate.
- Trial name
- DUTCH-ICD (NCT07415642)
- Testing
- ICD implantation
- Where
- 2 sites in Netherlands
- Volunteers
- 720 people
- Sponsor
- University Medical Center Groningen
Myocardial Infarction, Ventricular Tachyarrhythmia
Medical ANtiarrhythmic Treatment or Radiofrequency Ablation in Ischemic Ventricular Tachyarrhythmias
The study evaluates whether catheter based radiofrequency ablation is superior to optimized antiarrhythmic medical therapy in preventing ventricular tachyarrhythmia relapses in patients with ischemic heart disease and implantable…
- Trial name
- MANTRA-VT (NCT02303639)
- Testing
- Radiofrequency catheter ablation, Antiarrhythmic drug therapy
- Where
- 2 sites in Finland
- Volunteers
- 120 people
- Sponsor
- Central Finland Hospital District
Congestive Heart Failure
Does Lung Impedance Correlate With Changes in BNP in Stable and Acutely Decompensated Heart Failure Patients?
The purpose of this study is to determine whether there is a relationship between serial B-natriuretic peptide (BNP) and implantable device measured intrathoracic impedance in symptomatic and asymptomatic heart failure patients…
- Trial name
- IMPEDE-HF (NCT00560339)
- Where
- 6 sites in United States
- Volunteers
- 100 people
- Sponsor
- Southern New Jersey Cardiac Specialists
Ventricular Tachycardia, Coronary Artery Disease
Substrate Modification in Stable Ventricular Tachycardia in Addition to Implantable Cardioverter Defibrillator (ICD) Therapy
The main objective of this study is to compare the time from randomization to the first recurrence of any ventricular tachycardia (VT) in patients undergoing VT ablation (for stable VTs) and substrate ablation (for unstable VTs)…
- Conditions
- Ventricular Tachycardia, Coronary Artery Disease, Left Ventricular Dysfunction
- Trial name
- VTACH (NCT00919373)
- Testing
- Substrate modification, VT ablation, ICD Implantation
- Where
- 16 sites in Czechia, Denmark and 2 more
- Volunteers
- 110 people
- Sponsor
- Abbott Medical Devices
Ischemic Heart Disease
AnalyST Treadmill Study
The objective of the study is to collect information on the naturally occurring variations in ST deviations at different heart rates, as detected by the AnalyST and AnalyST Accel Implantable Cardioverter Defibrillators (ICD).
- Trial name
- NCT00949000
- Testing
- ICD Implantation
- Where
- 5 sites in Germany
- Volunteers
- 50 people
- Sponsor
- Abbott Medical Devices
Heart Failure With Reduced Ejection Fraction
The Effect of Combined Upper and Lower Extremity Endurance Training in Patients With ICD
It was aimed to examine whether the arm endurance exercise training is effective in addition to the lower cycling training program in order to alleviate the negative functional results in heart failure patients with ICD.
- Trial name
- ICD (NCT04803968)
- Testing
- bicycle ergometer and arm ergometer exercise, bicycle ergometer exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Hitit University
Anxiety, Pain
Impact of Virtual Reality on Anxiety and Pain During Implantation of Cardiac Implantable Electronic Devices (CIED)
Purpose: This study aimed to evaluate whether virtual reality technology positively affects patients' pain and anxiety throughout the entire procedure of implantation of cardiac pacemakers, defibrillators, or cardiac…
- Trial name
- CIED (NCT07250282)
- Testing
- Virtual reality headset
- Where
- Germany
- Volunteers
- 111 people
- Sponsor
- Muhammed Kurt
Tachycardia, Ventricular, Ventricular Fibrillation
A Randomized Trial of Remote Monitoring of Implantable Cardioverter Defibrillators Versus Quarterly Device Interrogations in Clinic
The purpose of this study is to determine if remote monitoring of implantable cardioverter defibrillators (ICD), compared with quarterly device interrogations in clinic, will improve patients' outcomes and satisfaction and will…
- Trial name
- Medusa SAK (NCT00606567)
- Testing
- Methods for monitoring patients with ICD's
- Where
- United States
- Volunteers
- 151 people
- Sponsor
- Duke University
Syncope, Bradycardia
Registry of Device Implantation
The implantable device therapy for cardiac arrhythmias has been an established therapy, and one of the common standard procedures in cardiac clinical practice.
- Conditions
- Syncope, Bradycardia, Tachycardia, Sudden Cardiac Death
- Trial name
- NCT03360227
- Testing
- implantation of cardiac devices
- Where
- Germany
- Volunteers
- 2,000 people
- Sponsor
- Klinik für Kardiologie, Pneumologie und Angiologie
ICD, Sudden Cardiac Death
Ability of Home Monitoring® to Detect and Manage the Inappropriate Diagnoses in Implantable Cardioverter Defibrillators.
The purpose of the THORN registry is to show the ability of Home-Monitoring® to early identify and manage the inappropriate diagnoses of ventricular arrhythmia in ICD patients (i.e.
- Conditions
- ICD, Sudden Cardiac Death, Ventricular Fibrillation, Atrial Fibrillation
- Trial name
- THORN (NCT01594112)
- Where
- 55 sites in France
- Volunteers
- 512 people
- Sponsor
- Biotronik SE & Co. KG
Congestive Heart Failure
Prospective Study on Prognosis of Cardiac Resynchronized Therapy (CRT), Implantable Cardioverter Defibrillator (ICD) Implantation in Patients With Congestive Heart Failure (CHF)
CRT and ICD has known as decreasing cardiac mortality in patient with heart failure. Especially, it has reported that CRT improved cardiac systolic function, quality of life of patients with heart failure.
- Trial name
- NCT02139449
- Testing
- ICD/CRT
- Where
- South Korea
- Volunteers
- 1,000 people
- Sponsor
- Yonsei University
Heart Failure, Implantable Cardioverter Defibrillator (ICD)
Upper Extremity Function in Patients With Reduced Ejection Fraction Heart Failure and Cardiac Implantable Electronic Devices
The aim of this study is to evaluate in detail the factors that determine upper extremity function, determine its effect on prognosis, hospital admission, hospitalization, and mortality, and examine the results according to the…
- Conditions
- Heart Failure, Implantable Cardioverter Defibrillator (ICD), Cardiac Resynchronisation Therapy (CRT), Reduced Ejection Fraction Heart Failure
- Trial name
- NCT07253909
- Testing
- Not applicable- observational study
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Hacettepe University
Primary Prevention, Tachycardia, Ventricular
Survival of Patients With Primary Prophylactic ICD Indication
The MADIT-II trial has shown that patients with severely reduced left ventricular ejection fraction (LVEF) post myocardial infarction benefit from the implantable cardioverter-defibrillator (ICD).
- Conditions
- Primary Prevention, Tachycardia, Ventricular, Sudden Cardiac Death
- Trial name
- SPIRIT-ICD (NCT00619593)
- Testing
- Intensified diagnostic and treatment measures following 1st appropriate ICD therapy, Standard follow-up
- Where
- 37 sites in Austria, Czechia and 9 more
- Volunteers
- 504 people
- Sponsor
- Biotronik SE & Co. KG