Clinical trials: Implantation Failure
Recurrent Implantation Failure, T-Shaped Uterus
Effect of Hysteroscopic Metroplasty on Reproductive Outcome in Patients with RIF
In recent years with the continuous improvement of ART technology, it has brought new hope to infertile couples, however more than half of the patients still experience multiple transfer failures.
- Trial name
- NCT06847386
- Testing
- Hysterocopic metroplasty
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Shanghai First Maternity and Infant Hospital
Mitral Regurgitation
MitraClip in Patients With Heart Failure
Multicenter observational study. The study does not involve any interventions in routine clinical practice, the choice of treatment method (including the type of medical device used and the method of surgical intervention) and…
- Trial name
- MitraClip (NCT06633159)
- Testing
- MitraClip
- Where
- Russia
- Volunteers
- 196 people
- Sponsor
- The League of Clinical Research, Russia
Peri-Implantation Loss, Periodontal Bone Loss
The Rehabilitation of Atrophic Jaws Using Short Implants With Different Surface Characteristics
The aim of the research is to evaluate the clinical outcome of short dental implants, characterized by a new macro-structural design and inserted in the upper or lower jaw in patients with reduced bone volume.
- Conditions
- Peri-Implantation Loss, Periodontal Bone Loss, Periimplantitis, Gingival Inflammation
- Trial name
- NCT05766878
- Testing
- implants placement
- Where
- 3 sites in Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Foggia
Dental Prosthesis Failure
RCT: Titanium vs FCZ vs Zirconia Framework
In recent years, zirconia-based implant-supported bridge designs have begun to be used more and more as an alternative to metal ceramic bridges.
- Trial name
- NCT05296291
- Testing
- High-translucent monolithic zirconia Bridge, Zirconium oxide ceramics Framework, Metal-ceramic Framework
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Branemarkkliniken
Capsular Contracture, Implant, Pediatric Cataract
Capsular Outcomes of Pediatric Cataract Surgery With Primary Intraocular Lens Implantation
Lens capsular often changes after pediatric cataract surgery，causing complications such as anterior capsulerhexis shrinkage, visual axis opacification (VAO), zonular dehiscence and so on.
- Trial name
- capsular (NCT04803097)
- Where
- China
- Volunteers
- 62 people
- Sponsor
- Yune Zhao
Heart Failure, Resynchronization Therapy
Acute Feedback on Left ventrIcular Lead Implantation Location for Cardiac Resynchronization Therapy
Exploratory, prospective, interventional, non-randomized single-center research study to compare metrics derived from 2 or 3-D reconstructions of lead movement, bioimpedance and VCG to augmentation of left ventricular…
- Conditions
- Heart Failure, Resynchronization Therapy, Assessment of Acute CRT Response
- Trial name
- CCI impact (NCT01996397)
- Testing
- Cardiac resynchronization therapy device implantation
- Where
- Norway
- Volunteers
- 34 people
- Sponsor
- Oslo University Hospital
End Stage Renal Disease
Post Market Study for VasQ, an External Support Implant for Arteriovenous Fistula
VasQ is an external support implant for arteriovenous fistulas created for dialysis access. This is a postmarket surveillance, prospective, multi-center, randomized, controlled, open label trial enrolling 300 patients randomized…
- Trial name
- NCT06516653
- Testing
- VasQ, Arteriovenous fistula creation for dialysis vascular access
- Where
- 13 sites in United States
- Volunteers
- 300 people
- Sponsor
- Laminate Medical Technologies
Heart Block, Heart Failure
Right Apical Versus Septal Pacing Trial
The purpose of this study is to examine whether RV (right ventricular)septal pacing has any effect on LV ( left ventricular) function than RV apical pacing in patients who require ventricular pacing.
- Trial name
- RASP (NCT00199498)
- Testing
- Apical RV lead placement, Septal RV lead placement
- Where
- Canada
- Volunteers
- 160 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Congestive Heart Failure, Cardiorenal Syndrome
Nesiritide and Renal Function After the Total Artificial Heart
The prevalence of renal dysfunction after implantation of the artificial heart is high. The infusion of exogenous B-type natriuretic peptide (BNP) after implantation of the total artificial heart (TAH) improves renal function in…
- Trial name
- NCT01836809
- Testing
- nesiritide
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Virginia Commonwealth University
Heart Failure, Myocardial Infarction
A Multinational Trial To Evaluate The Parachute Implant System
The primary objective is to assess the safety of the CardioKinetix Parachute Implant and Delivery System in the partitioning of the left ventricle in patients with heart failure due to ischemic heart disease.
- Trial name
- PARACHUTE (NCT01286116)
- Testing
- Parachute Implant
- Where
- 13 sites in France, Germany and 6 more
- Volunteers
- 59 people
- Sponsor
- CardioKinetix, Inc
Coagulation
Left Ventricular Assist Device (LVAD) Specialized Centers of Clinically Orientated Research (SCCOR) Coagulation - Acute Intrinsic Pathway Antagonist (IPA)
The purpose of this study is to determine if post-operative administration of intrinsic pathway antagonist (TTP889) in patients on Left Ventricular Assist Device (LVAD) support will result in a 50% reduction of thrombin…
- Trial name
- NCT00909298
- Testing
- TTP889
- Where
- 3 sites in United States
- Volunteers
- 2 people
- Sponsor
- vTv Therapeutics
Infertility
Effect of Intrauterine Injection of HCG on Clinical Pregnancy Outcome in Repeated Implantation Failure Patients
Repeated implantation failure（RIF） is a insurmountable bottleneck in assisted reproductive technology, many studies have considered that the cause of two-thirds of implantation failure is the decreased endometrial receptivity.
- Trial name
- NCT03682614
- Testing
- HCG, culture medium
- Where
- China
- Volunteers
- 47 people
- Sponsor
- Reproductive & Genetic Hospital of CITIC-Xiangya
Ischemic Congestive Heart Failure
Safety and Efficacy of Adipose Derived Stem Cells for Congestive Heart Failure
The intent of this clinical study is to answer the questions: 1. Is the proposed treatment safe 2. Is treatment effective in improving the disease pathology of patients with Heart Disease as assessed by a series of measurements…
- Trial name
- NCT01502514
- Testing
- Fat Harvesting and Implantation of Adipose Derived Stem Cells
- Where
- Mexico
- Sponsor
- Ageless Regenerative Institute
Prosthesis Durability
Ultrasound Investigation of Tongue Movement for Implant Overdenture
This study aimed to examine the impact of mandibular implant overdentures on tongue movement during mastication.
- Trial name
- NCT06705114
- Testing
- complete denture, implant overdenture
- Where
- Egypt
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Heart Failure, Diabetes Mellitus, Type 2
BIO-2-HEART: Identification of Biomarkers in T2DM and Heart Failure
The primary aim of the current study is a better understanding of the role of Type 2 Diabetes Mellitus (T2DM) in heart failure and, in particular, changes in cardiac metabolism, which may contribute to heart failure.
- Trial name
- BIO-2-HEART (NCT03323216)
- Testing
- 6-minute walk test, Study specific questionnaire, Blood collection
- Where
- Germany
- Volunteers
- 400 people
- Sponsor
- RWTH Aachen University
Recurrent Implantation Failure
Preimplantation Genetic Testing for Aneuploidies in Patients With Recurrent Implantation Failure
Assessing whether Preimplantation Genetic Testing for Aneuploidy (PGT-A) can increase the ongoing pregnancy rate per transferred embryo and can decrease the time to pregnancy and miscarriage rate in patients with Recurrent…
- Trial name
- NCT03900780
- Testing
- PGT-A, Control
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Glaucoma
Express Implant Versus Trabeculectomy After Late Failure Trabeculectomy
To compare between outcome of Express implant and subscleral trabeculectomy (SST) in management of glaucoma after previous trabeculectomy with a fibrotic bleb.
- Trial name
- NCT04417920
- Testing
- Express implant device
- Where
- Egypt
- Volunteers
- 28 people
- Sponsor
- Menoufia University
Unexplained Recurrent Miscarriage and Recurrent Implantation Failure
A Preliminary Study About Unexplained Recurrent Miscarriage and Repeated Implantation Failure Patients Treated With Low-dose Lymphocyte Immunotherapy
Recurrent miscarriage(RM) and recurrent implantation failure (RIF) are clinical challenge for clinicians and patients who are desperate for a healthy child.The specific etiology contains chromosomal abnormalities, reproductive…
- Trial name
- immunotherapy (NCT03081325)
- Testing
- low-dose lymphocyte immunotherapy
- Where
- China
- Volunteers
- 292 people
- Sponsor
- Nanjing University
Heart Failure
Right Ventricular (RV) Pacing in Early Post-operative Continuous Flow Left Ventricular Assist Device (LVAD)
Continuous right ventricular (RV) pacing demonstrates harm in patients with normal left ventricular (LV) function as well as in patients with cardiomyopathy and clinical heart failure.
- Trial name
- NCT01446796
- Testing
- Implantable Cardioverter-Defibrillator (subject's pre-existing ICD)
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Duke University
Orthodontic Anchorage Procedures
Failure Rate of Infra-Zygomatic Orthodontic Mini-Screws
The goal of this randomized clinical study is to assess the factors associated with the failure rate of infra-zygomatic crest orthodontic mini-screws used for anchorage reinforcement during orthodontic treatment.
- Trial name
- NCT07661277
- Testing
- Immediate loading infra-zygomatic mini-screw, Delayed loading infra-zygomatic mini-screw
- Where
- Bangladesh
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tanzila Rafique