Clinical trials: Implants
Edentulism
Accuracy of Metal Sleeve-Free Fully Guided Implant Surgery
This clinical trial aims to evaluate the in vivo accuracy of fully guided dental implant surgery using 3D-printed surgical guides without metal sleeves.
- Trial name
- NCT07364006
- Testing
- Standard Drilling Channel Metal Sleeve-Free Surgical Guide, Reduced drilling channel Metal Sleeve-Free Surgical Guide
- Where
- Spain
- Volunteers
- 15 people
- Sponsor
- Universidad Complutense de Madrid
Zygomatic Implants
Transforming Channel Osteotomy Into Tunnel Osteotomy in Zygomatic Implant Preparation
The evolution of zygomatic implant techniques, from the original procedures to the Zygomatic Anatomy-Guided Approach (ZAGA), has significantly improved outcomes for patients with severe maxillary atrophy.
- Trial name
- NCT07394179
- Testing
- Group A, Group B
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Fayoum University
Evaluate the Immediate Loading Implants in All on 4 Cases Using Conversion Denture and OT Bridge System
Splinted and Unsplinted OT Bridge Systems in Screw Retained Implant Restoration
Evaluation of Bone level changes around dental implants in All on 4 cases with immediate loading using conversion denture and OT Bridge system either splinted or not
- Trial name
- OTBS (NCT05031156)
- Testing
- Splinting of OT Bridge system
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Cairo University
Implants
Analysis of Specimens From Patients With Orthopaedic Implants
The investigators aim to determine the cause of failure of orthopaedic implants using multi-disciplinary analysis of data from patients who have undergone revision.
- Trial name
- NCT02566694
- Testing
- Implant
- Where
- United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Royal National Orthopaedic Hospital NHS Trust
Transient Ischemic Attack, Atrial Fibrillation
Early Detection Of Atrial Fibrillation In Patients With Transient Ischemic Attack
The purpose of this study is to determine the frequency of atrial fibrillation in patients with transient ischemic attack (TIA).
- Trial name
- NOTICE (NCT02011256)
- Testing
- Implantable loop-recorder
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- University of Southern Denmark
Guided Bone Regeneration
A Phase I Study of SB Cell for the Enhanced Osseointegration of Guided Bone Regeneration in Implant Surgery
This is a Phase 1 study to evaluate the safety profile of autologous-derived SB cells to enhance osseointegration of GBR in patients undergoing dental implant surgery.
- Trial name
- NCT04451486
- Testing
- SB cells
- Where
- Taiwan
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Tooth Loss, Soft Tissue Deficiency
A Clinical Study to Investigate Collagen Matrix 10808 for Soft Tissue Volume Augmentation Around Single Implants
The objective of this study is to investigate the safety and the function of the collagen Matrix 10808 in humans and to compare it versus the standard therapy, the transplantation of the autologous connective tissue graft.
- Trial name
- NCT02356770
- Testing
- Collagen Matrix 10808, Connective tissue graft
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Geistlich Pharma AG
Alveolar Ridge Enlargement
Leukocyte-platelet Rich Fibrin for Alveolar Ridge Preservation
After tooth extraction, there is a subsequent bone loss as a part of the natural healing of the tissue. Up to 50% of bone loss occurs during the first three months after extraction, jeopardizing a possible implant treatment.
- Trial name
- L-PRF (NCT05572242)
- Testing
- Premolar extraction and socked preservation with L-PRF, Premolar extraction and socked preservation with Xenogenic bone and collagen membrane.
- Where
- Chile
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Universidad de los Andes, Chile
Hemiparesis
Feasibility Study for Enhancing Gait Following Stroke With Implanted Microstimulators
The purpose of this study is to test an innovative, advanced FNS microstimulator technology developed by the Alfred Mann Foundation (Santa Clarita, CA) called, the Radio Frequency Microstimulation (RFM) Gait System that promises…
- Trial name
- NCT01640041
- Testing
- Radio-frequency Microstiumulator
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- The Alfred E. Mann Foundation for Scientific Research
Surgical Complications From Local Anesthesia, Dental Implant Failed
Compare Subperiosteal and Loco-Regional Anesthesia in Posterior Mandible Dental Implant Installation
In patients that are going to receive a dental implant in the posterior mandible (distal from canine), does the subperiosteal anesthetic technique with Articaine 1:100.000 4 % Epinephrine compared to the loco-regional one…
- Conditions
- Surgical Complications From Local Anesthesia, Dental Implant Failed, Anesthesia Complications, Anesthesia Morbidity
- Trial name
- NCT01963754
- Testing
- Dental Implants in Posterior Mandible, Subperiosteal 1:100.000 Articaine 4% epinephrine, Loco-regional 1:100.000 Articaine 4% epinephrine
- Where
- Portugal
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Implantology Institute
Microtia
Long-Term Follow-Up Study of Unilateral Microtia Patients Implanted With AUR-201
Long-term follow-up of unilateral microtia patients implanted with AUR-201.
- Trial name
- AUR-201 (NCT06078566)
- Testing
- AUR-201
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Auregen Biotherapeutics, SA
Breast Cancer
Hypofractionated Radiation Fractionation in Breast Cancer Patients With Implant-Based Reconstruction
It is a randomized trial to assess the safety and efficacy between hypofractionation radiation and conventional radiation in women who have undergone mastectomy and immediate breast reconstruction.
- Trial name
- HFIBR (NCT06830083)
- Testing
- Hypofractionated Radiation Therapy, Conventional fraction radiotherapy
- Where
- China
- Volunteers
- 840 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Failed Back Surgery Syndrome
A Novel Approach in Spinal Cord Stimulation: a Combination of Burst and Tonic Waveforms.
Spinal Cord Stimulation (SCS) has been a well-established treatment for chronic neuropathic pain in Failed Back Surgery Syndrome with associated legs and/or low back pain.
- Trial name
- NCT03201705
- Testing
- Burst + Tonic
- Volunteers
- 10 people
- Sponsor
- Massimo Innamorato
Breast Cancer, Breast Implant; Complications
Association of Silicone Breast Implants With Overall Wellbeingand Auto-immune Diseases
Background: Implant-based breast reconstructions contribute considerably to the quality of life of breast cancer patients. A knowledge gap exists concerning the potential role of breast implants in the development of so called…
- Conditions
- Breast Cancer, Breast Implant; Complications, Autoimmune Diseases
- Trial name
- AREOLA-B (NCT05400954)
- Testing
- Breast reconstruction with silicone breast implant, Breast conserving surgery/Mastectomy/Autologous reconstruction, Breast Augmentation
- Where
- 7 sites in Netherlands
- Volunteers
- 15,000 people
- Sponsor
- The Netherlands Cancer Institute
Cancer
Prophylaxis of Thrombosis With Implantable Devices for Central Venous Access in Cancer Patients
This is a Phase III open-labed, multicenter, prospective, randomised study, and comparative 3-arms of 140 patients (i.e. 420 total patients).
- Trial name
- NCT00199602
- Testing
- warfarine - low molecular heparin
- Where
- France
- Volunteers
- 420 people
- Sponsor
- University Hospital, Limoges
Thin Labial Plate
Long-Term Bone Dimensional Changes Following Flapless Immediate Implant Placement
Nowadays, achieving long-term hard tissue stability is the definitive goal of a successful immediate implant placement and has become the optimal challenge for clinicians over the past few decades.
- Trial name
- NCT07813494
- Testing
- IIP+Bone graft + CHA, IIP +CHA only
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- International Dental Contiuing Education
Diabetic Macular Edema, Pars Plana Vitrectomy
Compare the Efficacy of VItrectomy Combined With DExamethasone Implant Versus With Aflibercept in DME Patients Diagnosed by Intraoperative OCT (the VIDEO Study): Study Protocol for a Randomized Controlled Trial
Diabetic macular edema (DME) is the main cause of severe vision loss in diabetic retinopathy. Intravitreal injection of anti-vascular endothelial growth factor (VEGF) and Ozurdex are two safe and effective ways to treat DME.
- Conditions
- Diabetic Macular Edema, Pars Plana Vitrectomy, Dexamethasone Intravitreal Implant, Intraoperative Optical Coherence Tomography
- Trial name
- NCT05990829
- Testing
- Ozurdex, Aflibercept
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Tianjin Medical University Eye Hospital
Atrophy of Edentulous Maxillary Alveolar Ridge, Alveolar Bone Atrophy
Morphological Characteristics of Anterior Maxillary Bone and Dynamic Navigation in Full-Arch Implant Placement
The goal of this clinical trial is to evaluate the effectiveness of dynamic navigation in full-arch dental implant placement in patients with complete maxillary edentulism.
- Trial name
- NCT06974253
- Testing
- Nasopalatine Implants, Trans-Sinus Implants, and Trans-Nasal Implants for Full-Arch Rehabilitation
- Where
- Vietnam
- Volunteers
- 20 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Peri-implant Soft Tissue Healing
Soft Tissue Response and IL-1β Levels Around CAD/CAM-Milled vs 3D-Printed PMMA Healing Abutments
This study looked at how the gums and tissues around dental implants heal when using two different types of temporary healing caps made of PMMA (a common dental material).
- Trial name
- NCT07287722
- Testing
- CAD/CAM-Milled PMMA Healing Abutment, 3D-Printed PMMA Healing Abutment
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Ali Hassan Eid Toto
Otolaryngological Diseases Requiring Mastoidectomy, Middle Ear Surgery, Endolymphatic Sac Surgery, Cochlear Implant, Labyrinthectomy, Petrous Apex Lesions, Facial Nerve Surgery, and Lateral Skull Base Tumors
AI Recognition of Important Structures in Otolaryngological Surgery
Developing a system for artificial intelligence to recognize anatomical landmarks in otolaryngological surgery, enabling real-time tracking of critical temporal bone structures during surgery.
- Trial name
- NCT06726551
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
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