Clinical trials: Implants
Implant
Soft and Hard Tissue Changes After Immediate Single-tooth Replacement
A recent systematic review (Lee et al, 2016) reported that placement of a soft tissue graft concurrent with immediate implantation may contribute to the stability of gingival level and the augmentation of soft tissue contour.
- Trial name
- NCT03784430
- Testing
- Immediate dental implant placement, Immediate dental implant placement with CTG
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Università Vita-Salute San Raffaele
Ridge Augmentation
Autogenous Bone Ring Versus Split Bone Block for Management of Posterior Atrophic Mandible
Teeth loss in the posterior mandible initiates residual ridge resorption especially in vertical direction, this causes difficulty in implant placement so ridge augmentation must be done either simultaneous with implant placement…
- Trial name
- NCT07140887
- Testing
- Bone Ring, Split Bone block
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Alexandria University
Jaw, Edentulous, Partially
Straumann Roxolid Multi-Center Study
The primary objective of this study is to demonstrate non-inferiority of the Straumann Bone Level Ø 3.3 mm NC SLActive Roxolid Implants compared to Straumann Bone Level Ø 4.1 mm RC SLActive Roxolid Implants based on mean crestal…
- Trial name
- NCT01842958
- Testing
- Straumann Bone Level Implants, 4.1 mm implant diameter, Straumann Bone Level Implants, 3.3 mm implant diameter
- Where
- 5 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Institut Straumann AG
Patients Implanted With Monofocal Intraocular Lens
Prospective Evaluation of Near and Intermediate Visual Outcomes With Monofocal Intraocular Lenses: The Mast Study
The purpose of this study is to evaluate the near and intermediate visual outcomes of patients who have undergone routine cataract surgery (removal of cloudy crystalline lens) with phacoemulsification (the break-up and removal of…
- Trial name
- NCT01191515
- Testing
- Monofocal Intraocular Lenses
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Innovative Medical
Dental Implants
Dynamic Navigation vs. the Freehand Method
The purpose of the study is to evaluate in novice surgeons the accuracy of the X-Guide® navigation system (X-Guide®, X-Nav Technologies®, Pennsylvania, USA) in implant placement compared to freehand implant placement.
- Trial name
- NCT06028750
- Testing
- Dynamic Computer Assisted Surgery, Freehand
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Barcelona
Atrial Fibrillation
Atrial Fibrillation After Catheter Versus Thoracoscopic Ablation Using Patient Activated Implantable Loop Recorders: The ACTUAL Study
Atrial fibrillation (AF) is a common but often distressing condition. It can be treated with medications, but these are not always effective or tolerated.
- Trial name
- ACTUAL (NCT01503268)
- Testing
- Implantation of implantable loop recorder, Percutaneous ablation of atrial fibrillation, Surgical ablation of atrial fibrillation
- Where
- 2 sites in United Kingdom
- Sponsor
- East Sussex Healthcare NHS Trust
Atrophy of Edentulous Alveolar Ridge
Evaluation of Dental Implant Placement in the Sloped Alveolar Ridge
The aim of this study was to investigate the therapeutic effect of sloped dental implants. It can reduce the need of osteoectomy, reduce discomfort of procedures, and is easier for maintenance.
- Trial name
- NCT03543618
- Testing
- Sloped, Control
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Taiwan University Hospital
Nasolabial Fold Wrinkles
DL6049 vs CosmoPlast in the Treatment of Nasolabial Fold Wrinkles
This study is being undertaken to: evaluate the degree of correction attainable with DL6049 (injectable poly-L-lactic acid)compared to a commercially available CosmoPlast™ Collagen Implant in the treatment of dermal nasolabial…
- Trial name
- NCT00444210
- Testing
- DL6049 (injectable poly-L-lactic acid)
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Bausch Health Americas, Inc.
Dental Implant Bone Loss
A Randomized Controlled Clinical Trial to Assess Crestal Bone Remodeling of Four Different Implant Designs
This randomized controlled trial aimed to assess the effect of the implant neck design (microthreaded vs. non-microthreaded) as well as the type of abutment connection (internal conical vs.
- Trial name
- NCT06821308
- Testing
- Implant placement
- Where
- Belgium
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University Ghent
Platelet-rich Fibrin, Simvastatin
Effect of Local Application of Platelet-rich Fibrin Scaffold Loaded With Simvastatin on Peri-implant Bone Changes
ACKGROUND: Simvastatin (SIM), a pharmacological drug used for hypercholesterolemia, has been found to have pleotropic effects on bones. Simvastatin together with the appropriate carrier may decrease bone loss around implants.
- Trial name
- NCT05008068
- Testing
- Simvastatin
- Where
- Egypt
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- British University In Egypt
Hip Replacement
A Multicenter, Post-Market Clinical Follow-up Study of Subjects With the REDAPT™ System Monolithic Sleeveless/Sleeved Stem and/or Fully Porous Acetabular Shell With XLPE Liner and/or Modular Shell Components Previously Implanted
The primary purpose of this study is to demonstrate cumulative revision rate of the REDAPT System Monolithic Sleeveless/Sleeved Stem, Fully Porous Acetabular Shell with XLPE liner, and Modular Shell Components (with or without…
- Trial name
- NCT03610789
- Testing
- REDAPT
- Where
- 4 sites in United States
- Volunteers
- 220 people
- Sponsor
- Smith & Nephew, Inc.
Syncope
Adenosine Testing to DEtermine the Need for Pacing Therapy
The purpose of this study is to determine whether or not the intravenous adenosine test readily identifies patients with unexplained syncope who would benefit from permanent pacemaker implantation.
- Trial name
- ADEPT-ILR (NCT01481168)
- Testing
- Pacemaker implantation (Medtronic), Implantable Loop Recorder (Medtronic)
- Where
- 2 sites in United Kingdom
- Volunteers
- 52 people
- Sponsor
- Newcastle-upon-Tyne Hospitals NHS Trust
Hallux Valgus
Safety, Tolerability and Efficacy of HAVAI, for Correction of Inter-metatarsal Angle
A non-inferiority study to demonstrate efficacy of the HAVAI minimally invasive device compared to standard of surgical care 1st metatarsal osteotomy (SSOC)
- Trial name
- NCT02831868
- Testing
- HAVAI
- Where
- 2 sites in Israel
- Volunteers
- 30 people
- Sponsor
- Rabin Medical Center
Peri-Implantitis, Peri-implant Mucositis
Peri-implant Conditions Mimic Periodontal Conditions
Except for patients with referred clinical bruxism and uncontrolled medical conditions, the study included 123 implants with implanted fixed prostheses that had lasted at least six months after functional prosthetic loading.
- Conditions
- Peri-Implantitis, Peri-implant Mucositis, Peri-implant Health, Periodontitis
- Trial name
- NCT06128850
- Testing
- disease
- Where
- Turkey (Türkiye)
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Diabetes Mellitus, Type 2, Implant Complication
Posterior Narrow Diameter Implants in Hyperglycemic and Normo-glycemic Patients
The aim of the present study was to compare the initial healing and long term performance of narrow diameter implants in patients with uncontrolled Diabetes mellitus type 2 (T2DM) and healthy individuals.
- Trial name
- NCT04630691
- Testing
- Implantation
- Volunteers
- 35 people
- Sponsor
- University of Witten/Herdecke
Prostheses and Implants
The Effects of Large Head MoM Hip Prosthesis on Soft Tissue: Study With 3 Tesla NMR
Symptomatic and asymptomatic patients wearing Metal on Metal hip prosthesis will be enrolled in the study and periimplant pseudotumors will be searched by means of NMR (Nuclear Magnetic Resonance).
- Trial name
- MoM_&_3Tesla (NCT02793726)
- Testing
- NMR
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Istituto Ortopedico Rizzoli
Heart Failure, Sudden Cardiac Death
Prospective Clinical Registry of Subcutaneous Implantable Cardioverter Defibrillator (S-ICD) (S-ICD Korea Registry)
S-ICD avoids the use intravascular leads and their associated risks, has been increasingly used for primary and secondary prevention of sudden death.
- Conditions
- Heart Failure, Sudden Cardiac Death, Ventricular Tachycardia
- Trial name
- NCT04127643
- Where
- South Korea
- Volunteers
- 300 people
- Sponsor
- Yonsei University
Dental Implant Macrodesign, Dental Implant Surface Treatment
Effect of Implant Macro-Design and Surface Treatment on Insertion Torque and Early Implant Stability Quotient (ISQ)
This prospective, randomized pilot clinical trial will evaluate the effect of dental implant macro-design and surface treatment on insertion torque values (ITV) and early implant stability quotient (ISQ) trajectories in healed…
- Conditions
- Dental Implant Macrodesign, Dental Implant Surface Treatment, Dental Implant Primary Stability, Dental Implant Secondary Stability
- Trial name
- NCT07744776
- Testing
- Chairside implant surface treatment with Plasma X Motion device, SLA implant surface, Straumann BLT implant macro design
- Where
- Lithuania
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Dantu implantologijos centras
Fecal Incontinence, Anal Incontinence
Comparison of the Efficacy of a Biological Implant to Reinforce Overlapping Sphincter Repair Versus Overlapping Sphincter Repair Alone
The aim of this study is to compare the efficacy of Biodesign™ Surgisis® Tissue Graft to reinforce an overlapping sphincter repair versus the standard overlapping sphincter repair in controlling episodes of incontinence in…
- Trial name
- NCT01044589
- Testing
- Biodesign Tissue Repair Graft, Overlapping Sphincter Repair
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Massarat Zutshi
Dental Implant Placement
Supracrestal Tissue Attachment Dimensions & Peri-implant Health
Decision making in regards to the 3D implant positioning in partially edentulous sites is a complex process particularly when there are adjacent teeth present.
- Trial name
- NCT05552768
- Testing
- Bone level-driven placement, Biological width-driven placement guidelines
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- MIS Implant Technologies, Ltd
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