Clinical trials: Implants
Defibrillators, Implantable, Cardiac Arrest
Electrical Safety of Implantable Cardioverter Defibrillators
Patients at risk of developing life-threatening heart rhythms may require the implantation of a small device called a cardioverter-defibrillator (ICD), which constantly monitors the heart rhythm and delivers an electrical shock…
- Trial name
- NCT03271619
- Testing
- Surface current measurement
- Where
- United Kingdom
- Volunteers
- 25 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Dermatitis, Allergic Contact
Cutaneous and Systemic Reactions to Metal Implants
The purpose of this study is to evaluate if metal patch testing in metal allergic patients is useful for predicting the development of allergic skin disease or systemic symptoms in patients who recieve a metal orthopedic implant.
- Trial name
- NCT02483728
- Testing
- Patch Test
- Where
- 2 sites in United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Sleep-Disordered Breathing, Heart Failure
Validation of the ApneaScan Algorithm in Sleep Disordered Breathing
Sleep disordered breathing, in which patients my breath deeply, shallowly or stop breathing for periods whilst asleep, is common in heart failure and associated with a poor prognosis.
- Trial name
- ApneaScan (NCT02204865)
- Testing
- Pacemaker/ICD
- Where
- United Kingdom
- Volunteers
- 180 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Glaucoma
XEN Glaucoma Implant for the Management of Operated Uncontrolled Glaucoma: Results and Complications During a Long-Term Follow-Up
XEN Glaucoma Implant for the Management of Operated Uncontrolled Glaucoma: Results and Complications During a Long-Term Follow-Up
- Trial name
- NCT07350200
- Testing
- XEN implantation
- Where
- Poland
- Volunteers
- 150 people
- Sponsor
- Military Institute od Medicine National Research Institute
Osseointegrated Dental Implantation, Pain, Acute
OTC Naproxen and Acetaminophen Anti-Inflammatory Action in Dental Implant Patients
This double-blind pilot study will evaluate the anti-inflammatory and analgesic effects of an over-the-counter (OTC) regimen of naproxen sodium versus acetaminophen in patients receiving one or two (adjacent) dental implants.
- Trial name
- NCT04694300
- Testing
- Naproxen, Acetaminophen, Tramadol
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Hersh, Elliot V., DMD, MS, PhD
Tooth Extraction, Tooth Replacement
Comparison of Two Collagen Membranes for Bone Augmentation Around Dental Implants Restored with Monolithic Zirconia Single Crowns
The goal of this randomized controlled clinical trial is to compare the use of two covering collagen membranes in a bone augmentation procedure around single implants and to assess three different veneering approaches on crowns…
- Trial name
- BioGide-Compr (NCT06724783)
- Testing
- Collagen membrane
- Where
- Switzerland
- Volunteers
- 68 people
- Sponsor
- Dr. med. dent. Malin Strasding
Myopic Astigmatism
STAAR Visian Toric ICL Post-Approval Study
The objective of this study is to evaluate the long term (i.e. 24 months) clinical performance of the Visian® Toric Implantable Collamer® Lens (ICL).
- Trial name
- TICL-PAS (NCT04516772)
- Testing
- Visian TICL
- Where
- 8 sites in United States
- Volunteers
- 125 people
- Sponsor
- Staar Surgical Company
Immediate Dental Implant Placement, Immediate Dental Implant Loading
Influence of the Primary Stability and Temporary Prosthetics
The goal of this clinical trial is to to determine how different primary implant stability and loading management affect implant osseointegration and further function after one year.
- Conditions
- Immediate Dental Implant Placement, Immediate Dental Implant Loading, Marginal Bone Levels
- Trial name
- NCT07585539
- Testing
- Implant placement, Healing abutment, Temporary crown
- Volunteers
- 90 people
- Sponsor
- Tomas Linkevicius
Sleep Disorder, Cardiac Arrythmias
DEvice-Detected CArdiac Tachyarrhythmic Events and Sleep-disordered Breathing (DEDiCATES)
This prospective multicenter registry study aims to determine whether device-detected sleep-disordered breathing events are associated increased risk of cardiac arrhythmias or other cardiovascular outcomes.
- Conditions
- Sleep Disorder, Cardiac Arrythmias, Cardiac Event, Cardiac Implantable Electronic Device
- Trial name
- DEDiCATES (NCT03614377)
- Testing
- Device interrogation
- Where
- 15 sites in South Korea
- Volunteers
- 600 people
- Sponsor
- Samsung Medical Center
Alveolar Ridge Augmentation, Sinus Floor Augmentation
Evaluation of Two Different Techniques for Sinus Elevation, Open Versus Closed .
A clinical Trial, comparing two different techniques to elevate the maxillary sinus floor membrane to allow for simultaneous dental implant placement in the severely atrophied maxillary ridges.Both using allogenic bone substitute…
- Conditions
- Alveolar Ridge Augmentation, Sinus Floor Augmentation, Maxillary Sinus
- Trial name
- NCT06265467
- Testing
- Closed Sinus Elevation, Open Sinus Elevation
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Misr International University
Bone Loss
Using of Injectable Platelet Rich Fibrin on Filling the Gap of Immediate Dental Implant
The effect of using of i-PRF (injectable platelet rich fibrin) on filling the gap of immediate dental implant in the esthetic zone
- Trial name
- NCT04298294
- Testing
- injectable platelet rich fibrin
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Bone Resorption, Tooth Loss
Hyaluronic Acid Effect on Xenogenic Bone Healing
The aim of this study is to test the hyaluronic acid hydrogel impact on the healing acceleration of xenogenic bone substitutes used in ridge preservation.
- Trial name
- NCT04377256
- Testing
- Ridge preservation: Tooth extration and immediat bone grafting in the socket
- Where
- 2 sites in Lebanon
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Saint-Joseph University
Hearing Loss in Children With Unilateral or Bilateral Cochlear Implants
Feasibility and Reliability of Integrating Electrically Evoked Stapedius Reflex Threshold (eSRT) Measurement in a Pediatric Cochlear Implant Programming Center
In children aged 0 to 7 years, behavioral evaluation during cochlear implant programming is often difficult or unreliable. Objective, reproducible, and rapid markers are therefore essential.
- Trial name
- eSRT2 (NCT07417956)
- Testing
- Electrically Evoked Stapedius Reflex Threshold (eSRT) Measurement
- Where
- France
- Volunteers
- 48 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Chest Wall Tumor
Clinical Trial on the Efficacy and Safety of Biodegradable 3D-Printed Implants in Chest Wall Reconstruction Surgery
This project focuses on patients with chest wall tumors who are expected to have a maximum intraoperative anterolateral chest wall defect diameter of 5-10 cm and require chest wall reconstruction with rib implants.
- Trial name
- NCT06977022
- Testing
- Chest wall reconstruction
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Tang-Du Hospital
Soft Tissue Augmentation
Clinical Evaluation of Soft Tissue Augmentation Using CTG and PRF Around Immediately Placed Dental Implants Versus Immediate Implant Alone in Esthetic Zone .
The main hypothesis to be certified is that the addition of Subepithelial Connective Tissue Graft (SCTG) and Platelet rich Fibrin (PRF) to immediately placed implants will not significantly differ from immediately placed implant…
- Trial name
- NCT03413553
- Testing
- immediate implant, connective tissue graft, platelet rich fibrin
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Abeer hassan sharafuddin
Bilateral Vestibular Loss
VertiGO! - Get up and GO! With the Vestibular Implant
In the VertiGO! trial 13 participants with bilateral vestibulopathy (BV) and severe sensory neural hearing loss in the ear to be implanted will receive a combined cochlear (CI) and vestibular implant (VI), capable of stimulating…
- Trial name
- NCT04918745
- Testing
- Cochlear Vestibular Implant (CVI) - in-hosptial, Cochlear Vestibular Implant (CVI) - home-use (preference)
- Where
- Netherlands
- Volunteers
- 13 people
- Sponsor
- Maastricht University Medical Center
Atrial Fibrillation
The Efficacy of Single Coil Defibrillation Leads for Internal Cardioversion of Atrial Fibrillation
This study seeks to determine the efficacy of single coil defibrillation leads for cardioversion of persistent atrial fibrillation.
- Trial name
- NCT03164395
- Testing
- Internal Cardioversion, External Cardioversion
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Kentucky
Femoral Neck Fracture, Infection
Early Periprosthetic Joint Infection and Outcome Debridement, Antibiotics and Implant Retention
Introduction Periprosthetic joint infection (PJI) is a severe complication to hip arthroplasty for femoral neck fractures (FNF).
- Trial name
- DAIR (NCT02771639)
- Testing
- Hip arthroplasty
- Volunteers
- 736 people
- Sponsor
- Sundsvall Hospital
Patient Reported Outcome Measures, Patient Satisfaction
Patient-reported Outcomes and Esthetics With Single Dental Implants
The goal of this observational study is to investigate patient-reported long-term outcomes of single dental implants. Therefore, the aim of the study is to describe patient-reported functional and esthetic outcomes of single…
- Conditions
- Patient Reported Outcome Measures, Patient Satisfaction, Implant Complication
- Trial name
- NCT06571201
- Where
- Sweden
- Volunteers
- 45 people
- Sponsor
- Kristianstad University
GERD
Evaluation of Safety and Effectiveness of the RefluxStop Device in the Management of GERD
Prospective, open-label, multi-centre, single arm treatment only trial to evaluate the safety and effectiveness of RefluxStop for the treatment of GERD.
- Trial name
- NCT02759094
- Testing
- Treatment with RefluxStop
- Where
- 4 sites in Hungary, Serbia
- Volunteers
- 50 people
- Sponsor
- Implantica CE Reflux Ltd.
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