Clinical trials: Implants
Cochlear Prosthesis Implantation
Impact of Microphone Positioning on Auditory Performance in Cochlear Implant Users
The construction of our auditory space requires several prerequisites, including localization abilities in 3D (azimuth, elevation and distance).
- Trial name
- MICLO (NCT04677517)
- Testing
- Modification of active microphone positioning, SPHERE protocol, French Matrix Test
- Where
- France
- Sponsor
- Hospices Civils de Lyon
Implant Complication
Clinical and Radiographic Evaluation of Immediate Implant Placement Using Osseodensification Versus Traditional Drilling Protocol
For the purpose of the study, patients will be divided into two groups, i.e., Group A and Group B. In Group (A), 14 immediate implants will be placed using traditional drilling technique, while in Group (B), 14 immediate implants…
- Trial name
- NCT06307691
- Testing
- Conventional drilling, Osseodensification drilling
- Where
- Egypt
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cairo University
Mammaplasty, Radiotherapy; Complications
Adjuvant Radiotherapy's Effect on One and Two Stages Prosthetic Breast Reconstruction and on Autologous Reconstruction
For patients with breast cancer subject to a mastectomy, preserving the morphology of the breast with immediate reconstruction is a crucial aspect to preserve the quality of life.
- Conditions
- Mammaplasty, Radiotherapy; Complications, Breast Implant; Complications, Transplant Failure
- Trial name
- NCT04783818
- Testing
- Adjuvant Radiotherapy
- Where
- Italy
- Volunteers
- 3,200 people
- Sponsor
- Humanitas Clinical and Research Center
Total Hip Arthroplasty (THA)
A Safety Follow Up Study in Australian Subjects Implanted With the SMF Short Modular Femoral Stem Hip System
This is a prospective, single arm, sequential enrolment study to collect relevant clinical and radiological data in approximately 26 subjects, at one site in Australia, who have been implanted with the SMF Short Modular Femoral…
- Trial name
- NCT03646513
- Testing
- SMF Short Modular Femoral Hip System
- Where
- Australia
- Volunteers
- 4 people
- Sponsor
- Smith & Nephew, Inc.
Congenital Hearing Loss, Sensorineural Hearing Loss
Alpha-Tectorin, Interleukin-10 and Thiol-Disulfide Homeostasis in Children With Congenital Hearing Loss
Congenital hearing loss is one of the most common sensory disorders of childhood, and the structural, immunologic and oxidative mechanisms involved in its development are incompletely understood.
- Trial name
- NCT07860580
- Testing
- Blood sample collection
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Harran University
Osteoarthritis, Knee, Inflammation Knees
How TKA Implants Affect Muscle Quality and Activity During Daily Living and Immunological Response
This study compares two total knee replacement implants to asses muscle function and quality, and the immune response to the implants.
- Trial name
- NCT04105179
- Testing
- Zimmer NexGen LPS-Flex, Smith & Nephew Journey II
- Where
- Canada
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Echocardiography, Implantable Chamber
Evaluation of the Contribution of the Ultrasound Tracking and the Positioning of the Distal End During the Implantation of Implantable Chamber or Long-lasting Venous Catheter
Given the increase in the number of PAC implants or long-term catheters, and the ease of access to cardiac ultrasound in the operating theaters, the investigator thought to use ultrasound to PAC or long-term catheters.
- Trial name
- EchoPAC (NCT03133962)
- Testing
- Adult patients who are candidates for a CAP or long-term central catheter placement
- Where
- France
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Edentulous Jaw
T3 Certain Tapered With DCD vs T3 Certain Tapered Non-DCD
This will be a prospective, randomized multicenter study to determine the safety and efficacy of the T3 Certain Tapered with DCD as compared to T3 Certain Tapered without DCD.
- Trial name
- Apple (NCT04354688)
- Testing
- T3 Certain Tapered Implant
- Where
- 2 sites in Chile, Greece
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- ZimVie
Edentulous Alveolar Ridge, Bone Atrophy, Alveolar
Crestal vs Lateral Sinus Lift Augmentation
The aim of this randomised controlled trial (RCT) of split-mouth design was to compare patient preference and effectiveness of two different techniques for lifting the maxillary sinus: the crestal approach versus the lateral…
- Trial name
- NCT04111250
- Testing
- Maxillary sinus augmentation
- Where
- Albania
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Hospital San Pietro Fatebenefratelli
Edentulous Jaw
Comparison of Accuracy of Full-arch Implant Digital and Conventional Impressions.
The goal of this clinical trial is to determine whether the accuracy of digital impressions is comparable to conventional impressions. It will also learn about the clinical effect of different method.
- Trial name
- NCT07190820
- Testing
- digital impression, conventional impression
- Where
- China
- Volunteers
- 24 people
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Glaucoma, Open-Angle, Ocular Hypertension
Clinical Study Comparing Two Models of a Travoprost Intraocular Implant
Phase III study to compare the safety and efficacy of intraocular implants containing Travoprost at two different elution rates versus Timolol Maleate Ophthalmic Solution, 0.5% (Timolol) in reducing elevated intraocular pressure…
- Trial name
- NCT03868124
- Testing
- G2-TR intraocular implant containing travoprost
- Where
- United States
- Volunteers
- 560 people
- Sponsor
- Glaukos Corporation
Preparation of the Implant Site With Piezosurgery vs Drill
Observational Study on the Preparation of the Implant Site With Piezosurgery vs Drill: Comparison Between the Two Methods in Terms of Post-operative Pain, Surgical Times and Operational Advantages
Purpose: Recent advances showed that ultrasonic implant site osteotomy is related with a decreased trauma and a better post operative healing of the surgical site if compared to the traditional drilling techniques.
- Trial name
- NCT03978923
- Testing
- preparation of the implant site with Piezosurgery vs drill
- Where
- Italy
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Trieste
Papilla Reconstruction
Modified Pedicle Subepithelial Connective Tissue Graft for Interdental Papillary Reconstruction Around Delayed Implants in the Esthetic Zone: A Case Series Trail
This case series trial aims to evaluate the effect of a modified pedicle subepithelial connective tissue graft in creating anatomical papilla around one-stage delayed implant in the esthetic zone to establish better esthetics.
- Trial name
- delay implant (NCT04843826)
- Testing
- papilla reconstruction
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Ahmed Sadek Mohamed
Movement Disorders, Dystonia
Brain Sensing in Neurological and Psychiatric Disorders
High-frequency deep brain stimulation (DBS) is an effective treatment strategy for a variety of movement disorders including Parkinson's disease, dystonia and tremor1-5, as well as for other neurological and psychiatric disorders…
- Conditions
- Movement Disorders, Dystonia, Parkinson Disease, Tremor
- Trial name
- NCT04810325
- Volunteers
- 65 people
- Sponsor
- University College, London
Congestive Heart Failure
External Sensors for remoTe MoniToring of Heart Failure Patients With Implantable Defibrillators
This study has been designed to describe the use of Remote Patient Management (RPM) systems equipped with sensors for the measurement of weight and blood pressure in an Italian health care setting, verifying their efficacy and…
- Trial name
- ESTIMATE-HF (NCT02147340)
- Where
- Italy
- Volunteers
- 186 people
- Sponsor
- Maurizio Eugenio Landolina
Single-Sided Deafness
Anatomy Based Selection of CI Array for SSD Patients
The purpose of the study is to evaluate cochlear implant speech outcomes and subjective benefit for cochlear implant recipients with single-sided deafness using patient-specific, anatomy-based array selection versus standard of…
- Trial name
- NCT06189274
- Testing
- Anatomy-Based Electrode Array Selection, Standard of Care Electrode Array Selection
- Volunteers
- 10 people
- Sponsor
- Nova Scotia Health Authority
Breast Cancer
A Comparative Study of Delayed Endoscopic DTI and Latissimus Dorsi ±Impalnt Reconstruction Post-Mastectomy
Breast cancer is the most common malignancy in women. In 2022, China saw about 357,200 new cases and 75,000 deaths, accounting for 15.59% and 7.94% of all new cancer cases and cancer-related deaths, respectively.
- Trial name
- DELTI (NCT07757074)
- Testing
- Surgery options
- Where
- China
- Volunteers
- 268 people
- Sponsor
- Du Zhenggui
Bone Cancer, Bone Diseases
Massive Implants the Next Generation
The study will review the use of massive segmental replacements in the femur, which have a porous collar with and without HA, and autologous stem cell augment. This is a randomised controlled trial.
- Trial name
- MING (NCT03905174)
- Testing
- custom made device
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Iva Hauptmannova
Periodontitis, Periodontal Disease
Short Implants in Unitary Implant-supported Rehabilitations in the Posterior Maxilla and Mandible: 5 Years of Follow-up
Implant-supported rehabilitation of regions with severe bone resorption is a challenge for implant dentists. Structures such as the maxillary sinus and the inferior alveolar canal often make it impossible to use implants of…
- Trial name
- NCT07688408
- Testing
- bone loss
- Where
- Brazil
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Guarulhos
Edentulism
A Pilot Randomized Clinical Study Comparing Patient-Reported Outcomes and Complications for Mandibular Implant Overdentures Retained by Different Splinted Attachment Systems
This exploratory pilot randomized clinical study enrolled ten completely edentulous participants who experienced retention and stability problems with conventional mandibular complete dentures.
- Trial name
- M15011122 (NCT07373340)
- Testing
- overdentures with bar locator attachments, overdentures with bar ball attachments
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Mansoura University
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