Clinical trials: Implementation, open to volunteers
Microalbuminuria, Microalbuminuria /Creatinine Ratios ACR
New Taipei City 888 Digital Medical AI Platform for Prevention and Care of the Three Highs and Cardio-Renal-Vascular Diseases
Non-communicable diseases (NCDs), or chronic diseases, are a major public health burden globally and in Taiwan, and control of the "three highs" (hypertension, dyslipidemia, and hyperglycemia) is a national priority.
- Conditions
- Microalbuminuria, Microalbuminuria /Creatinine Ratios ACR, Cardiovascular Disease Risk Factor, Cardiovascular Disease Prevention
- Trial name
- DIGICARE-DREAM (NCT07588256)
- Testing
- Interactive digital modules, Antihypertensive Medication Management
- Where
- Taiwan
- Volunteers
- 4,162 people
- Sponsor
- New Taipei City Medical Association
Breast Cancer
Strength After Breast Cancer
The goal of this study is to explore whether a group exercise program called Strength After Breast Cancer can be delivered in an outpatient physical therapy clinic to improve physical function among women after treatment for…
- Trial name
- SABC (NCT06052488)
- Testing
- Strength After Breast Cancer
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- MGH Institute of Health Professions
Mental Health Issue
Implementation Supports to Reduce Burnout in Therapists Delivering Child Trauma EBPs
The majority of children exposed to early adversity and trauma do not have access to sustainably delivered evidence-based mental health programs (EBPs), despite the growing prevalence of large-scale multiple-EBP implementation…
- Trial name
- SUPPORTS (NCT04712461)
- Testing
- SUPPORTS
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Atherosclerotic Cardiovascular Disease (ASCVD), Coronary Artery Calcification
Health Enhanced Artery Risk Tracking With Widespread Implementation and Screening Effort in ASCVD (HEARTWISE-ASCVD)
This multi-site study will test whether an opportunistic AI-based CAC screening and notification intervention can improve cholesterol treatment and lower cholesterol levels in adults.
- Trial name
- HEARTWISE (NCT07355894)
- Testing
- AI-Detected CAC Notification and Care Facilitation
- Where
- 6 sites in United States
- Volunteers
- 120,000 people
- Sponsor
- Stanford University
Sepsis, Antimicrobial Resistance (AMR)
Implementation of a Sepsis Chart and Its Effects on Mortality Rate in Indonesian Primary Referral Hospitals
The goal of this observational study is to evaluate the effectiveness of implementing Koran Sepsis, or sepsis chart, a paper-based order set designed to guide the implementation of the One-hour Sepsis Bundle, in improving…
- Trial name
- NCT07843277
- Testing
- Sepsis chart (koran sepsis), Usual care
- Where
- 2 sites in Indonesia
- Volunteers
- 304 people
- Sponsor
- Dr Cipto Mangunkusumo General Hospital
Gynaecologic Cancer
Improving Sexual Health in Gynecological Cancer Patients
The goal of this clinical trial is to test whether a nurse-led program can improve screening and referral rates for sexual dysfunction and improve sexual health care in individuals with gynecological cancer.
- Trial name
- NCT07144566
- Testing
- Nurse Led Sexual Health Clinical Program Intervention
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Cedars-Sinai Medical Center
Depression
Empower@Home: Hybrid Effectiveness-Implementation Randomized Controlled Trial (RCT)
This study is a randomized Type I hybrid effectiveness-implementation trial aimed at evaluating the effectiveness of Empower@Home, an internet-delivered cognitive-behavioral therapy (CBT) program supported by aging service…
- Trial name
- NCT06584422
- Testing
- Empower@Home: An online cognitive-behavioral therapy self-care program for geriatric depression, Telephone friendly visits
- Where
- United States
- Volunteers
- 256 people
- Sponsor
- University of Michigan
Neutropenic Fever
Antibiotic Stewardship in Suspected Neutropenic Fever (ASTERIC Trial)
Executive Summary Background: Neutropenic Fever (NF), or febrile neutropenia, occurs in patients with early stage and metastatic solid tumours, non-leukaemic haematological cancers and acute leukaemia.
- Trial name
- NCT06794320
- Testing
- NF Protocol, ASTERIC protocol
- Where
- Hong Kong
- Volunteers
- 648 people
- Sponsor
- The University of Hong Kong
Mental Health, Mental Well-being
Study of Self-Help and Support Services for Student Mental Health in Tertiary Institutions
This proposed study aims to evaluate the implementation of integrating the existing services in tertiary education institutions with the JCTH+ platform.
- Conditions
- Mental Health, Mental Well-being, Psychological Intervention, Self-care
- Trial name
- NCT06623682
- Testing
- Transdiagnostic cognitive behavioural therapy
- Where
- Hong Kong
- Volunteers
- 1,684 people
- Sponsor
- Chinese University of Hong Kong
Hiv
Resilient HIV Implementation Science With SGM Youths Using Evidence
The Resilient HIV Implementation Science with SGM Youths using Evidence (RISE) Clinical Research Center will use a Type 2 hybrid-effectiveness-implementation study to evaluate the effectiveness and implementation of HMP, a…
- Trial name
- RISE (NCT06350682)
- Testing
- HealthMPowerment (HMP)
- Where
- 3 sites in Nigeria, Zambia
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Sedentary, Suboptimal Health Status
Supporting Preventive Practices in Primary Care: Amplifying the Potential of Opportunistic Interventions
In France, as worldwide, the prevalence of chronic conditions is increasing, with high burden on populations and healthcare systems.
- Trial name
- APPRENDRE (NCT07391462)
- Testing
- Training for GPs to learn healthy conversation skills for supporting patients' health behavior change, No training for GP
- Where
- 4 sites in France
- Volunteers
- 882 people
- Sponsor
- Hospices Civils de Lyon
Surgery, Geriatric Assessment
Implementation Pilot of Preoperative CGA Before Major Surgery
The goal of this clinical trial is to test whether a new implementation package can help older adults prepare for major surgery.
- Conditions
- Surgery, Geriatric Assessment, Health Services Research, Implementation Science
- Trial name
- NCT06184724
- Testing
- Implementation Package for CGA, Routine Clinical Care
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
HIV, HIV Antiretroviral Therapy (ART) Adherence
Transitional Housing and HIV Health
The goal of this pilot study is to evaluate the implementation and outcomes of the Arms Around You (AAY) program, a supportive housing initiative launched by the Philadelphia Department of Public Health (PDPH) in 2024.
- Conditions
- HIV, HIV Antiretroviral Therapy (ART) Adherence, Housing Instability
- Trial name
- NCT06829394
- Testing
- Program Assignment
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- University of Pennsylvania
Breast Cancer
Clinical Breast Examination and Patient Navigation Intervention in Sub-Saharan Africa
Brief summery Prolonged presentation, along with diagnostic and treatment delays, remain significant problems for breast cancer care in sub-Saharan Africa , primarily due to low health-seeking behaviour, lack of access, long…
- Trial name
- NCT07023198
- Testing
- Clinical breast examination and Navigation
- Where
- Ethiopia
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- Addis Ababa University
HCC - Hepatocellular Carcinoma
Treatment Selection by 3D Bioprinting Liver Model to Prevent Liver Cancer Recurrence
This study is a feasibility study about a test on adjuvant therapy for patients in hepatocellular carcinoma (HCC) with a higher risk of tumour recurrence after liver resection or ablation.
- Trial name
- NCT07839767
- Testing
- Liver-in-cube testing
- Where
- Hong Kong
- Volunteers
- 20 people
- Sponsor
- The University of Hong Kong
Diabetes, Coronary Artery Disease
Electronic Real-Time Heart Team Decision-making vs. Usual Care in Patients With Triple-Vessel Coronary Artery Disease and Diabetes Mellitus
This is a multi-center randomized controlled trial involving patients with 3-vessel coronary artery disease and diabetes mellitus.
- Trial name
- EHEART-3VD (NCT07326514)
- Testing
- Real-Time Heart Team Decision-making
- Volunteers
- 1,350 people
- Sponsor
- China National Center for Cardiovascular Diseases
Intracerebral Haemorrhage
NICardipine for Fast Achievement of Systolic BP Targets in ICH
Quality improvement study with a quasi-randomized design. The study monitors the effect of a gradually implemented treatment algorithm prioritizing intravenous antihypertensives (e.g., nicardipine) over long-acting nitrate…
- Trial name
- NICFAST (NCT07044232)
- Testing
- Nicardipine, Glyceryl trinitrate
- Where
- Denmark
- Volunteers
- 88 people
- Sponsor
- Aarhus University Hospital
Dementia, Cognitive Dysfunction
Preventing Loss of Independence Through Exercise in Community Living Centers
Approximately 40,000 older Veterans with complex care needs receive long-term care in VA Community Living Centers (CLCs). Many CLC staff have limited specialized training to engage Veterans with dementia.
- Trial name
- PLIE-CLC (NCT06972004)
- Testing
- Preventing Loss of Independence through Exercise (PLIE)
- Where
- United States
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Suicide, Attempted, Suicide, Fatal
Implementation of Suicide Risk Models in Health Systems
The goal of this clinical trial is to evaluate a suicide risk model in patients receiving behavioral health care treatment. The main question it aims to answer is: Does the implementation of the suicide risk model reduce suicide…
- Trial name
- NCT06060535
- Testing
- Suicide Attempt Risk Model Care Pathway
- Where
- 3 sites in United States
- Volunteers
- 394,000 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Home Based Rehabilitation, Acute Coronary Syndromes
Development and Implementation Model of Home Based Cardiac Rehabilitation With Family Empowerment Approach in Patient With ACS (HBCR in ACS)
The aim of this clinical trial is to determine whether home-based cardiac rehabilitation with a family empowerment approach can help acute coronary syndrome patients recover.
- Trial name
- HBCR in ACS (NCT06625463)
- Testing
- Home based cardiac rehabilitation
- Where
- 2 sites in Indonesia
- Volunteers
- 90 people
- Sponsor
- Gadjah Mada University