Clinical trials: Implementation, open to volunteers
Venothromboembolism
AI-driven Clinical Decision Support to Reduce Hospital-Acquired Venous Thromboembolism: Study Protocol for the VTE-AI Randomized Trial.
Hospital-acquired blood clots (HA-VTE) are the leading cause of death in hospitalized patients in the US. Each year, about 900,000 people get blood clots, costing between $7 and $10 billion in medical expenses.
- Trial name
- VTE-AI RCT (NCT06939803)
- Testing
- Risk model-driven CDS
- Where
- United States
- Volunteers
- 2,236 people
- Sponsor
- Vanderbilt University Medical Center
Stroke, Stroke Rehabilitation
Enhancing Resilience Among Patients With Stroke: Implementation of High Intensity Home-based Rehabilitation
The goal of this observational study is to test whether a model of high-intensity home-based rehabilitation (HIHR) helps patients get good outcomes after treatment for a stroke at Duke University Hospital.
- Trial name
- HIHR (NCT07098286)
- Testing
- high intensity home-based rehabilitation
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Duke University
Age-Related Cognitive Decline
EMBRACE - From Vulnerable to Empowered: Implementation and Evaluation of a Multicomponent Program to Tackling Age-related Decline
EMBRACE is a randomized, controlled, multi-domain, blinded clinical trial involving 120 community-dwelling older adults at risk of cognitive decline, lasting 12 months.
- Trial name
- EMBRACE (NCT07628686)
- Testing
- EMBRACE Intervention
- Where
- Portugal
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Fernando Pessoa
Heart Failure
Improving TRansitions ANd OutcomeS for Heart FailurE Patients in Home Health CaRe (I-TRANSFER-HF)
This study is trying to improve the hospital-to-home transition for people with heart failure who receive home care services. The study will test an intervention called I-TRANSFER-HF, which differs from usual care by combining…
- Trial name
- NCT06118983
- Testing
- I-TRANSFER-HF
- Where
- 2 sites in United States
- Volunteers
- 1,094 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Colorectal Cancer, Colorectal Neoplasms
PRIORITY-CONNECT 2 Trial
Objectives: The primary aim of this project is to establish the effectiveness of an individualised stepped, multidisciplinary intervention, including education and peer support group, delivered via a virtual multimodal…
- Trial name
- PC2 (NCT06976710)
- Testing
- Preoperative Exercise, Postoperative Exercise, Preoperative Nutrition
- Where
- 31 sites in Australia
- Volunteers
- 564 people
- Sponsor
- Surgical Outcomes Research Centre (SOuRCe)
Infection, Rickettsia Infections
Implementation of an RT-PCR Assay for the Diagnosis of Rickettsia Spp. Infection
Rickettsia2024 is a multicenter, tissue observational, retrospective and prospective cohort study. Enrollment will take place within the outpatient clinics of the Infectious Diseases and Dermatology Unit of the IRCCS AOUBO and…
- Trial name
- NCT07307651
- Where
- 2 sites in Italy
- Volunteers
- 800 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Substance Use Disorder, Opioid Use Disorder
Testing the CrOss Systems Technical Assistance for Retaining Staff (COSTARS) Model for Improving Staff Retention Among Child Welfare Workers and Peer Supporters, and Implementation of Evidence Based Interventions.
The goal of this study is to test whether the CrOss System Technical Assistance for Retaining Staff (COSTARS) supervision leadership institute can promote workforce stability and improved implementation outcomes within the Ohio…
- Conditions
- Substance Use Disorder, Opioid Use Disorder, Child Maltreatment, Implementation
- Trial name
- COSTARS (NCT07439783)
- Testing
- COSTARS, Implementation As Usual
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Alicia Bunger
Heart Failure With Reduced Ejection Fraction
Digital Support Program for Patients With Heart Failure - a Cluster-Randomized Hybrid Type 2 Study
The overall aim of this project is to evaluate the effects of a digital support program for patients with heart failure through a cluster-randomized controlled trial, and to investigate the outcomes of different implementation…
- Trial name
- NCT07275931
- Testing
- Tailored implementation support
- Where
- Sweden
- Volunteers
- 240 people
- Sponsor
- Linkoeping University
Psychiatric Problem, Child Neglect
Implementing Dyadic Developmental Psychotherapy (DDP) - Evaluation Research
The objective of this study is to evaluate the implementation and use of Dyadic Developmental Psychotherapy (DDP) in three centra, with particular focus on its potential effects on the quality of the observable caregiver-child…
- Conditions
- Psychiatric Problem, Child Neglect, Maltreatment, Child Behavior Problem
- Trial name
- NCT04763720
- Testing
- Dyadic Developmental Psychotherapy
- Where
- Norway
- Volunteers
- 100 people
- Sponsor
- Sykehuset Telemark
Hypertension
Implementation of a Beauty Salon-Based Strategy for Blood Pressure Management Among Women
CROWN is a two-arm, cluster-randomized pilot trial testing the feasibility and preliminary efficacy of a salon-based cardiovascular intervention - training stylists as Heart Health Stylists to conduct in-salon blood pressure…
- Trial name
- CROWN (NCT07042386)
- Testing
- CROWN Intervention, Enhanced Usual Care
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Stroke
Effects of Group Leisure Activities and Musical Training on Hospital Stroke Rehabilitation.
The goal of this clinical trial is to learn whether adding group leisure activities and musical training can help people recover better after a stroke during their hospital rehabilitation.
- Trial name
- RehArt (NCT07541560)
- Testing
- Standard Intensive Stroke Rehabilitation Program, Music-supported Therapy, Enriched Intervention
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- Escola Universitària d'Infermeria i Teràpia Ocupacional de Terrassa
Alcohol Use Disorder
The Connect Trial: Connecting Hospital Patients to Alcohol Care
The main objective of this pilot study is to assess feasibility of conducting a definitive RCT with concealed allocation, blinded outcome assessment and a 1:1 parallel group design of A) an invitation to meet an AUD therapist for…
- Trial name
- NCT07482150
- Testing
- AUD treatment sessions with an outreach alcohol therapist at the hospital, Guidance and leaflet on AUD treatment facilities outside the hospital
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Zealand University Hospital
Rare Diseases, Albinism
Implementation of Long-read Sequencing for the Diagnosis of Rare Diseases.
Following on from the third national plan for rare diseases (PNMR3), the main objectives of the PNMR4 are to reduce diagnostic uncertainty and dead ends and to strengthen translational research to promote diagnosis and the…
- Conditions
- Rare Diseases, Albinism, Intellectual Disability
- Trial name
- LongEpi (NCT07400913)
- Testing
- Long-read sequencing
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Bordeaux
Loneliness, Sleep Quality
Mindfulness for Lonely Older Adults With Emigrant Children
This study is to examine the feasibility of a proposed mindfulness-based intervention (MBI) and study methodology for future main study.
- Conditions
- Loneliness, Sleep Quality, Quality of Life, Stress
- Trial name
- NCT07711860
- Testing
- Intervention, Active Control
- Where
- Hong Kong
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Hong Kong Metropolitan University
Knowledge, Attitudes, Practice
Core Competency Model for Corrections
The overall goal of this project is to design, implement, and revise the Core Competency Model for Corrections (CCM-C), an evidence-based Self-Directed Violence (SDV) prevention training program for correctional mental health…
- Trial name
- CCM-C (NCT06359574)
- Testing
- Core Competency Model for Corrections (CCM-C) Self-Directed Violence Prevention Training
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of North Carolina, Charlotte
Hiv, Alcohol Use, Unspecified
Practice Facilitation as a Strategy to Improve Alcohol Treatment Adoption and Implementation in HIV Care
Despite availability of evidence-based alcohol reduction interventions (EBI), unhealthy alcohol use remains a barrier to HIV medication adherence, viral suppression and retention in HIV care and consequently HIV treatment as…
- Trial name
- NCT05241990
- Testing
- Practice Facilitation, Alcohol Stepped Care
- Where
- 3 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Hypertension
Implementation of a Person-Centered and Integrated Care Pathway for Hypertension
The aim is to investigate whether information and educational initiatives on the Swedish national care pathway for hypertension, directed at primary care centers, lead to an increase in the proportion of patients achieving target…
- Trial name
- IMPLEMENT-HT (NCT07914283)
- Testing
- Educational intervention for doctors and nurses
- Volunteers
- 120,000 people
- Sponsor
- Region Stockholm
Stroke, Hypertension
BRIDGE: Blood Pressure Reduction and Intervention Delivery Via Group Engagement
The investigators want to improve care for people who have had a stroke. High blood pressure is the leading cause for having a second stroke and can lead to poor brain health.
- Conditions
- Stroke, Hypertension, Home Blood Pressure Monitoring, Implementation Research
- Trial name
- BRIDGE (NCT07091851)
- Testing
- Group medical visits and home blood pressure monitoring
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Massachusetts General Hospital
Human Papillomavirus Infection
Investigating Facilitator-driven, Multi-level Implementation Strategies in Federally Qualified Health Centers to Improve Provider Recommendation and HPV Vaccination Rates Among Latino/a Adolescents
The purpose of this study is to determine the provider- and practice-level characteristics that influence the impact of implementation strategies guided by practice facilitation in each clinical practice, to test whether the…
- Trial name
- NCT06598475
- Testing
- Facilitator-driven provider- and practice-level implementation strategies for influencing provider recommendations and practice-level HPV vaccination rates
- Where
- United States
- Volunteers
- 225 people
- Sponsor
- The University of Texas Health Science Center, Houston
Substance Use Disorders, Pregnancy Related
Implementation of a Patient-centered, Reproductive Planning Decision Support Tool (MyPath) Among Women With Substance Use Disorder in the Immediate Postpartum Period
This is a study to determine the effect of a novel patient-centered, reproductive planning decision support tool developed by the research team called MyPath on postpartum contraceptive decision-making among women with SUDs.
- Conditions
- Substance Use Disorders, Pregnancy Related, Contraception
- Trial name
- IMPACT (NCT04939012)
- Testing
- MyPath Intervention, Usual care
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- University of Pittsburgh
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