Clinical trials: Implementation, open to volunteers
Diabetic Retinopathy
I-TRUST: Implementation of Teleophthalmology in Rural Health Systems Study
This pragmatic clinical trial is being conducted to test the effectiveness of I-SITE (Implementation for Sustained Impact in Teleophthalmology), an implementation program to sustain increased diabetic eye screening rates using…
- Trial name
- NCT05254535
- Testing
- I-SITE
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Wisconsin, Madison
Mental Health
Effectiveness and Implementation of a School-based Mental Well-being Intervention Among Adolescents of Bharatpur, Nepal
The goal of this study is to evaluate the effectiveness and assess the implementation of CROSS-MIND, a school-based mental well-being intervention for adolescents in Nepal. The study uses a Hybrid Type 1 mixed-methods design.
- Trial name
- CROSSMIND_NP (NCT07812168)
- Testing
- CROSS-MIND
- Where
- Nepal
- Volunteers
- 1,060 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Labor Induction, Cesarean Birth
Implementation of a Disparities in Labor Outcomes Dashboard
This proposal will determine if a Disparities in Labor Outcomes dashboard can be used as an implementation strategy to increase compliance to an evidence-based set of interventions for labor induction in a two-site…
- Trial name
- NCT07756424
- Testing
- Disparities in Labor Outcomes Dashboard
- Where
- United States
- Volunteers
- 2,300 people
- Sponsor
- University of Pennsylvania
Education, Medical
Implementation of Anal Cancer Screening and Treatment in Nigeria
The study is a feasibility pilot trial testing 2 types of training protocols on a single physician. The first training protocol is the current standard and was developed in high-income settings.
- Trial name
- IMPACT (NCT05817370)
- Testing
- Enhanced Training on screening and treatment of HSIL (e-STH)
- Where
- Nigeria
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Hematologic Cancer, Acute Myeloid Leukaemia (AML)
Home-based Intravenous Cytarabine Treatment for Acute Myeloid Leukemia: a National Danish Study of Feasibility, Costs, and Implementation
The goal of this observational multicenter feasibility and implementation study is to evaluate home-based treatment with intravenous Cytarabine for patients with acute myeloid leukemia in Denmark.
- Conditions
- Hematologic Cancer, Acute Myeloid Leukaemia (AML), Hospital At Home, Home-based Chemotherapy
- Trial name
- HOME-CALM (NCT07802015)
- Volunteers
- 80 people
- Sponsor
- Zealand University Hospital
Head and Neck Neoplasms, Emergency Department Presentation
Access to Care Pilot for ED-Presenting Head and Neck Cancer Patients (ENRICH-HNC)
Patients diagnosed with head and neck cancer (HNC) after presenting to an emergency department (ED) often face significant delays in diagnosis and treatment.
- Conditions
- Head and Neck Neoplasms, Emergency Department Presentation, Head and Neck Cancer (H&N)
- Trial name
- ENRICH-HNC (NCT07225725)
- Testing
- Community Health Support Specialist (CHSS) Navigation
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- University of Tennessee
Vascular Access Devices, Vascular Access
Impact of a Long Peripheral Venous Catheter Protocol in Pediatric and Neonatal Care
The purpose of this study is to evaluate the impact of a training intervention aimed at nursing personnel on the appropriateness of the indication of long peripheral venous catheters in candidate pediatric and neonatal patients…
- Conditions
- Vascular Access Devices, Vascular Access, Vascular Access Complication
- Trial name
- NCT07870876
- Testing
- Training program on long peripheral catheter insertion
- Volunteers
- 33 people
- Sponsor
- Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
Pelvic Bone Injury, Sacral Fracture
Impact of a Clinical Pathway for Pelvic Fragility Fractures
Patients with pelvic fragility fractures suffer from high morbidity and mortality rates. Despite the high incidence of these injuries, there is currently no regional or nationwide treatment protocol which results in a wide…
- Conditions
- Pelvic Bone Injury, Sacral Fracture, Pelvic Fracture, Fragility Fracture
- Trial name
- PELVIC (NCT06054165)
- Testing
- Clinical pathway
- Where
- 8 sites in Netherlands
- Volunteers
- 393 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Peritoneal Dialysis (PD), Large Language Models
Peritoneal Dialysis (PD) Specialized LLM for PD Management
This study conducted a randomized controlled trial using clinical vignettes to evaluate differences in the quality of PD management among two large language model-assisted workflows and a physician-only decision-making process…
- Trial name
- PIONEER-PD (NCT07539428)
- Testing
- Peritoneal dialysis-specialized large language model., Generalized LLM tools such as deepseek
- Where
- China
- Volunteers
- 150 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Fall
AI-assisted Fall Prevention Through Evidence
The goal of this multi-method study is to investigate how AI-assisted fall-prevention are implemented in routine hospital care what their effects are.
- Trial name
- SAFE (NCT07503665)
- Testing
- Not applicable- observational study
- Where
- Sweden
- Volunteers
- 23,425 people, healthy volunteers welcome
- Sponsor
- Halmstad University
Substance-Related Disorders, Adverse Childhood Experiences
Evaluating an Adverse Childhood Experience-Targeting Advocate Model of a Substance Use Prevention Program
Primary Objective: Conduct a rigorous evaluation of a prevention-based intervention designed to mitigate the harms of adverse childhood experiences (ACEs) exposure and prevent future ACEs, substance use, and overdose within 36…
- Trial name
- NCT06236100
- Testing
- Strengthening Families Program + Family Advocate, Strengthening Families Program
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- RTI International
Family Relationships, Child Mental Health
A Program Evaluation of the Brief Family Therapy Program in the York University Psychology Clinic
Background. Children are vulnerable to mental health challenges during development. Given that youth are reliant on their parents for support, understanding the child's symptoms within the family context is critical for promoting…
- Conditions
- Family Relationships, Child Mental Health, Coparenting
- Trial name
- NCT07161063
- Testing
- Brief Family Therapy Program
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- York University
Depression and Suicide Ideation, Anxiety
Culturally Adapted Psychological Support for Conflict-Affected Afghans: Study Protocol on Mental Health & Violence
This pilot study examines the feasibility and acceptability of a culturally adapted psychological intervention-Problem Management Plus with Emotional Processing (PM+ EP)-for young Afghans aged 16-30 experiencing high…
- Conditions
- Depression and Suicide Ideation, Anxiety, PTSD
- Trial name
- NCT06980441
- Testing
- Problem Management Plus with Emotional Processing module
- Where
- Afghanistan
- Volunteers
- 60 people
- Sponsor
- Peace of Mind Association (PoMA)
Mental Health
Evaluation of the Gambling Habits of Adolescents and Young Adults Post-COVID-19 and Implementation of a Digital Escape Room Intervention for Preventing Gambling in High School Students
Gambling behaviors among adolescents and young adults have been experiencing an upward trend in the last years, possibly because of new habits developed during the COVID-19 lockdown restrictions.
- Trial name
- NCT06904794
- Testing
- GAMBL-OUT program
- Where
- Spain
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Hospital Miguel Servet
Hospital-associated Deconditioning
Promoting Increased Physical Activity in Hospitalised Older Adults
The PIVOT study will explore the feasibility of training volunteers to deliver exercise to hospitalised older adults to improve the health of older people and prevent deconditioning while in hospital.
- Trial name
- PIVOT (NCT06017934)
- Testing
- Volunteer-led physical activity
- Where
- 2 sites in United Kingdom
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- University of Southampton
Organ Donation After Circulatory Death, Organ Donation
Improving Deceased Organ Donation and Transplantation Using the Donation Advisor Clinical Decision Support Tool
Every year, thousands of Canadians receive life-saving, cost-effective organ transplants, while thousands more still wait or die because not enough organs are available.
- Conditions
- Organ Donation After Circulatory Death, Organ Donation, Clinical Decision Support Tool
- Trial name
- DART (NCT07903428)
- Testing
- Donation Advisor clinical decision-support tool
- Volunteers
- 10 people
- Sponsor
- OBS Medical Ltd
Cancer, Lymphoma
A Study Of Remote Patient Monitoring (RPM) Program For Cancer Patients Initiating Cancer-directed Therapy
This clinical trial develops and studies whether using a new remote patient monitoring (RPM) program [Smart Health Integration for Early Life-saving Detection (SHIELD)] in cancer practices helps manage infectious complications…
- Trial name
- NCT07810400
- Testing
- Smart Phone Application-based Intervention - SHIELD, AION TempShield, Questionnaires
- Where
- United States
- Volunteers
- 470 people
- Sponsor
- Mayo Clinic
Post-traumatic Stress Disorder (PTSD), Post-traumatic Stress Symptoms
Developing and Testing Innovative Care Pathways for Screening and Treatment of OUD/PTSD in Jails
Opioid overdose is the leading cause of death among people recently released from incarceration. Recent evidence also shows a rise in stimulant use among justice-involved populations, as well as growing rates of concurrent opioid…
- Conditions
- Post-traumatic Stress Disorder (PTSD), Post-traumatic Stress Symptoms, Opioid Use Disorder (OUD), Stimulant Use Disorder
- Trial name
- HOPE (NCT07490717)
- Testing
- Cognitive Processing Therapy (CPT), Written Exposure Therapy (WET)
- Where
- 2 sites in United States
- Volunteers
- 338 people
- Sponsor
- University of Arkansas
Breast Cancer, Early Detection of Cancer
Strategies to Decentralize Breast Ultrasound in Rwanda
Diagnosing breast cancer early is critical to reduce preventable breast cancer deaths in sub-Saharan Africa. This can be done in part through increasing patients' access to breast ultrasound, which is essential for evaluating…
- Conditions
- Breast Cancer, Early Detection of Cancer, Ultrasonography
- Trial name
- NCT06812208
- Testing
- Teleultrasound with Philips Lumify ultrasound probes and Reacts software, Asynchronous virtual feedback
- Where
- Rwanda
- Volunteers
- 1,792 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Psychomotor Disadaptation Syndrome
The Benefits of Virtual Reality in the Care of Elderly People With Psychomotor Disadaptation Syndrome
Psychomotor Disadaptation Syndrome (PMDS) is characterised by a deterioration in postural function, gait and psychomotor automatisms in the elderly.
- Trial name
- VIR-AGE (NCT07026890)
- Testing
- Evaluation visits, Rehabilitation sessions, Virtual reality sessions
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
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