Clinical trials: Implementation Research
Program Effectiveness, Program Implementation
Implementation Study With Embedded RCT of a Digital System of Parenting Support Within Government Services in South Africa
ParentText, a WhatsApp-based parenting support programme, is designed as a universal intervention to improve parent-child relationships (module 1) and promote child safety (module 2).
- Conditions
- Program Effectiveness, Program Implementation, Parent Child Relationship, Caregiver Child Relationship
- Trial name
- SWIFT (NCT07814261)
- Testing
- Module 1 - Improve My Relationship with My Teen/Child, Module 2 - Keep My Child/Teen Safe and Healthy
- Where
- South Africa
- Volunteers
- 4,961 people, healthy volunteers welcome
- Sponsor
- University of Cape Town
Mental Health
Bundled Intervention Integrating Mental Health Services in Nepal
Globally, access to mental healthcare is often non-existent in rural, resource-deprived communities despite the pervasive need for services, particularly in post-conflict and post-disaster settings.
- Trial name
- NCT02376062
- Testing
- Bundled Intervention
- Where
- 2 sites in Nepal
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Possible
Colorectal Carcinoma
Implementation of a ColoRectal Cancer Screening Tool in US Primary Care Practices - Usual Quality Improvement (10 Clinics) vs Normalization Process Theory-Participatory Learning in Action (10 Clinics)
Although implementation intentions (I2)-based tools enhance colorectal cancer (CRC) screening uptake, prior studies have not tested their implementation into routine primary care delivery.
- Trial name
- (PB-iCRC) (NCT06682650)
- Testing
- NPT-PLA, Usual Quality Improvement
- Where
- United States
- Volunteers
- 2,200 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Children with Undergoing Rehabilitation
Virtual Reality Implantation in Paediatric Rehabilitation (IMPLANT-VR4 CHILD)
Virtual Reality Implementation in Paediatric Rehabilitation (IMPLANT-VR 4 CHILD) Virtual Reality (VR) and Active Video Games (AVG) are promising devices for children in need of rehabilitation.
- Trial name
- IMPLANT-VR4 (NCT06627049)
- Testing
- Focus group, Implementing facilitating strategies, Interviews
- Where
- 2 sites in France
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Fondation Ildys
Malaria
Factors Influencing Adoption of a Novel Malaria Treatment in Côte d'Ivoire, Ghana, and Rwanda
This non-interventional qualitative study will examine factors that influence the adoption of a novel malaria treatment in Côte d'Ivoire, Ghana, and Rwanda.
- Trial name
- NCT07896746
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Novartis Pharmaceuticals
Maternal and Child Health, Health Service Utilization
Integrated Community Based Health Systems Strengthening in Northern Togo
The general objective of this study is to optimize implementation and assess effectiveness of the integrated facility and community-based health systems strengthening (ICBHSS) model in four Northern Togo districts, using the…
- Trial name
- ICBHSS-Togo (NCT03694366)
- Testing
- ICBHSS model
- Where
- Togo
- Volunteers
- 7,600 people, healthy volunteers welcome
- Sponsor
- Integrate Health
Domestic Violence Against Women, Community-based Prevention
Community Based Intervention to Prevent Domestic Violence Against Women in Ethiopia; a Protocol for Quasi-Experimental Implementation Research
Violence against women is a well understood devastating global pandemic, and human right violation. One in three women experienced intimate partner violence worldwide.
- Conditions
- Domestic Violence Against Women, Community-based Prevention, Interevntion Implementation
- Trial name
- NCT03265626
- Testing
- Intervention 1: Comprehensive preventive intervention, Intervention 2: Awareness creation and community mobilization, available standard care
- Where
- Ethiopia
- Volunteers
- 1,217 people, healthy volunteers welcome
- Sponsor
- Haramaya Unversity
Fruit and Vegetable Consumption
Effectiveness and Implementation of a Research Tested Mobile Produce Market
Investigators will test the effectiveness of the Veggie Van model across multiple organizations and sites using a cluster-randomized design and will document the implementation process to understand what factors are associated…
- Trial name
- NCT04246593
- Testing
- Mobile Market program implementation
- Where
- United States
- Volunteers
- 759 people, healthy volunteers welcome
- Sponsor
- University at Buffalo
Tuberculosis Infection, Latent, Tuberculosis Active
SCAF-TB - Saving Children and Their Families From Tuberculosis: Implementation Research to Improve TB Preventive Treatment Initiation and Completion Rates Among Contact Persons in Tajikistan and Tanzania
The SCAF-TB study aims to evaluate how the WHO-endorsed SIILTIBCY skin test can be best implemented to test close contacts for tuberculosis infection (TBI) in Tajikistan and Tanzania, either facility-based or home-based delivered…
- Conditions
- Tuberculosis Infection, Latent, Tuberculosis Active, TPT
- Trial name
- SCAF-TB (NCT07714707)
- Testing
- CY-TB Patch, Audiblehealth DX
- Where
- 2 sites in Tajikistan, Tanzania
- Volunteers
- 880 people, healthy volunteers welcome
- Sponsor
- KNCV Tuberculosis Foundation
Communication
Evaluation of a Communication Skills Training for Nurses
The KOMPAT study aims to evaluate the effectiveness and feasibility of a needs-based communication skills training for nursing professionals in Germany and to derive recommendations for future long-term implementation.
- Trial name
- KOMPAT (NCT05700929)
- Testing
- Communication skills training for nurses
- Where
- Germany
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
ADHD - Attention Deficit Disorder With Hyperactivity, ADHD
Research on the Development, Implementation Effect and Neural Mechanism of a Physical Intervention Program for College Students With ADHD Based on the Characteristics of Balance Dysfunction
Background: Attention deficit/hyperactivity disorder is a common neurodevelopmental disorder. Its core symptoms and related executive function, emotional and motor coordination problems often persist into adulthood, significantly…
- Conditions
- ADHD - Attention Deficit Disorder With Hyperactivity, ADHD, ADHD - Combined Type, ADHD - Inattentive Type
- Trial name
- NCT07499427
- Testing
- Aerobic Treadmill Training, Progressive Balance Training, Cognitive-Balance Dual-Task Training
- Where
- China
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Wuhan Sports University
Evidence-Based Practice, Nurse's Role
Feasibility and Effectiveness of the Advancing Research and Clinical Practice Through Close Collaboration (ARCC)
The Institute of Medicine's (IOM) ambitious goal for at least 90% of clinical decisions to be evidence-based includes nursing interventions and practice.
- Trial name
- ARCC (NCT03269331)
- Testing
- CTEP EBP Immersion
- Where
- United States
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- David Grant U.S. Air Force Medical Center
Child Mortality
REACH2: Implementation Research on Bi-Annual Mass Distribution of Azithromycin to Children 1-11 Months in Côte d'Ivoire
REACH2 is a three-year implementation research study designed to examine the implementation through a mass drug administration platform of bi-annual single-dose azithromycin to reduce child mortality among children ages 1 to 11…
- Trial name
- REACH (NCT05016895)
- Testing
- Single-dose azithromycin
- Where
- Côte d’Ivoire
- Volunteers
- 767,535 people, healthy volunteers welcome
- Sponsor
- FHI 360
Covid-19 Vaccination
Effect of Messaging on Pragmatic Outcomes Within an Integrated Healthcare System
COVID-19 vaccination among patients at high risk for severe disease has declined in the United States since 2022. Prior research, including discrete choice experiments (DCEs), has demonstrated that vaccine preferences are…
- Trial name
- EMPOWeR (NCT07838038)
- Testing
- Vaccine choice message, Vaccine choice + platform-framed message, Vaccine choice + HCP trust-framed message
- Where
- United States
- Volunteers
- 1,300,000 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente