Clinical trials: Improvement in Function
Worksite Health Promotion, Lifestyle Risk Reduction
Intervention to Increase Physical Activity and Wellbeing Among Staff and Residents in Assisted Living Facilities
The purpose of the study is to test a program that aims to help staff increase wellness behaviors and test the impact of this program on staff and work outcomes.
- Conditions
- Worksite Health Promotion, Lifestyle Risk Reduction, Occupational Burnout, Healthcare Workers
- Trial name
- WHHIP+FFC 2026 (NCT07785947)
- Testing
- WHHIP, FFC
- Where
- United States
- Volunteers
- 344 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Parkinson Disease
Strategy for Daily Activity Improvement in Patients With Parkinson's Disease
The symptoms and signs of patients with Parkinson's disease (PD) include bradykinesia, rigidity, tremor and poor sensory integration, which result in mobility disability.
- Trial name
- Parkinson (NCT03972241)
- Testing
- foot insole
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kwan-Hwa Lin
Sub-optimal Cognitive Function, Sub-optimal Immune Function
Evaluating Whole Foods Supplementation on Cognition
A six-month study which investigated the effect of Ginkgo Synergy® and Choline or OPC Synergy® and Catalyn® on cognitive and immune function markers and quality of life among healthy older adults with no history of significant…
- Trial name
- NCT01672359
- Testing
- Ginkgo Synergy® and Choline, OPC Synergy® and Catalyn
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- University of Miami
Intestinal Health
Research on the Improvement of Intestinal and Immune Functions by Probiotics
Evaluate the effectiveness and safety of Limosilactobacillus fermentum LF61 as a food supplement compared to a placebo in improving intestinal and immune functions in healthy adults.
- Trial name
- NCT06873425
- Testing
- Probiotic
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Wecare Probiotics Co., Ltd.
Infertility, Female, Perimenopausal Disorder
Autologous Platelet Rich Plasma (PRP) Intra Ovarian Infusion in Perimenopausal Women
Autologous PRP intra ovarian infusion may improve ovarian response and women's hormonal profile and may promote folliculogenesis in perimenopausal women.
- Conditions
- Infertility, Female, Perimenopausal Disorder, Menstrual Cycle Abnormal
- Trial name
- PRP (NCT03951194)
- Testing
- Autologous Platelet Rich Plasma (PRP) intra ovarian infusion
- Where
- Greece
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Genesis Athens Clinic
Aging
Phosphatidylserine Improves Cognitive Function in the Elderly
Cognitive decline is a common symptom of aging, and age-related cognitive impairments are considered normal or inevitable, especially in people over 60, whose memory is more likely to be affected by age.
- Trial name
- PICFITE (NCT04920305)
- Testing
- Phosphatidylserine, Bean powder
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Upper Extremity Dysfunction, Gait, Unsteady
The Effect of Improvement in Function on Foot Pressure, Balance and Gait in Children With Upper Extremity Affected
It has been shown that movements of the upper extremity during walking are associated with lower extremity mobility. For example, when walking at a slow pace, the swing frequency of the arms is 2: 1 compared to the legs, while…
- Conditions
- Upper Extremity Dysfunction, Gait, Unsteady, Juvenile Idiopathic Arthritis, Balance
- Trial name
- NCT04671524
- Testing
- Exercise protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Cardiovascular Diseases
Improvement of Endothelial Function by EGCG
Cardiovascular diseases are a major cause of morbidity and mortality worldwide. Impaired endothelial function (assessed as flow-mediated dilation) represents an early marker for later cardiovascular events.
- Trial name
- NCT01662232
- Testing
- Green tea beverage, Green tea extract, EGCG
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Adolescent Mental Health, Adolescent - Emotional Problem
A Validation Study of the Neuro-cognitive Emotion Monitoring-Intervention (NEMO-I) Application in Adolescents
This study aims to evaluate the validity and effectiveness of NEMO-I (Neuro-cognitive Emotion Monitoring-Intervention), a mobile application designed to help adolescents monitor and manage their cognitive and emotional…
- Conditions
- Adolescent Mental Health, Adolescent - Emotional Problem, Cognition Improvement
- Trial name
- NCT07700264
- Testing
- NEMO-I (Neuro-cognitive Emotion Monitoring-Intervention)
- Where
- South Korea
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Seoul Women's University
Asthma, Vitamin D Deficiency
A Study to Investigate the Effect of Vitamin D3 Supplementation on Asthma Symptoms in Adults With Asthma (VITDAS)
Asthma is a disease characterised by chronic inflammation of the airways leading to symptoms including periods of shortness of breath, wheezing and a tight chest due to airway narrowing in affected patients.
- Conditions
- Asthma, Vitamin D Deficiency, Nutritional Deficiency, Inflammation
- Trial name
- VITDAS (NCT04117581)
- Testing
- Vitamin D3
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Chester
Healthy Adults With Subjective Memory Complaints
Effects of Deer Bone Extract NS on Improvement in Cognitive-Bio-Markers of Cognitive Functions
This study aims to elucidate the effects of deer bone extract NS on cognitive function improvement and its safety in healthy adults aged 40 to 65 years who report decline in subjective cognitive functions using multimodal…
- Trial name
- NCT02379481
- Testing
- NS 550mg, NS 1100mg
- Where
- South Korea
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ewha Womans University
Mitochondrial Function, Bioenergetics, Muscle Function
Bioenergetics and Muscle Function Improvement With AMAZ-02 in Elderly Skeletal Muscle (ENERGIZE Trial)
This is a randomized, double-blind, single-center, placebo-controlled Phase 2 trial enrolling 66 healthy elderly subjects (33 placebo and 33 AMAZ-02 administration) who are ≥65 and ≤ 90 years of age with evidence of low…
- Conditions
- Mitochondrial Function, Bioenergetics, Muscle Function, Aging
- Trial name
- NCT03283462
- Testing
- Mitopure
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Amazentis SA
Ulcerative Colitis, Irritable Bowel Syndrome
Fecal Microbiota Transplantation for Health Improvement (TFM3)
Search for mechanisms of the effect of fecal transplantation on a healthy organism and various nosological forms.
- Conditions
- Ulcerative Colitis, Irritable Bowel Syndrome, Crohn Disease, Irritable Bowel
- Trial name
- TFM3 (NCT04011943)
- Testing
- Fecal Microbiota Transplantation
- Where
- Russia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Federal Research and Clinical Center of Physical-Chemical Medicine
Intestinal and Immune Function Improved
The Effect of Probiotics on the Improvement of Intestinal and Immune Function
Evaluate the effectiveness and safety of Lactobacillus delbrueckii subsp. bulgaricus LB42 as a food supplement compared to a placebo in improving intestinal and immune functions in healthy adults.
- Trial name
- NCT06873438
- Testing
- Probiotic group
- Where
- China
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Wecare Probiotics Co., Ltd.
Abnormal Mental State, Schizophrenia
Effects of 'Seroquel-XR' on the Improvement of Neurocognitive Function in People At-risk Mental States(ARMS)
The primary objective of this study is to assess the effects of 'Seroquel-XR' on the verbal learning ability in people with at-risk mental state (ARMS) over a 12 week period.
- Trial name
- ES-ARMS (NCT01250847)
- Testing
- Quetiapine(Seroquel-XR) 50~800mg a day
- Where
- 2 sites in South Korea
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Severance Hospital
Worksite Health Promotion, Lifestyle Risk Reduction
Worksite Wellness Within Long-term Care Facilities
The goal of this proposed study is to test the feasibility and preliminary efficacy of worksite wellness program designed to reduce worker stress (job and personal) and improve cardiovascular disease among long-term care workers.
- Conditions
- Worksite Health Promotion, Lifestyle Risk Reduction, Cardiovascular Diseases, Occupational Stress
- Trial name
- NCT04166643
- Testing
- WHHIP PLUS, Education only control
- Where
- United States
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Vision, Low
eSight Eyewear Quality of Life and Efficacy Study
The "eSight Quality of Life and Efficacy Study" (eQUEST) is a prospective cohort study intended to demonstrate the functional vision and Quality of Life (QoL) improvement provided by eSight Eyewear to persons with significant…
- Trial name
- eQUEST (NCT02616900)
- Testing
- eSight Eyewear
- Where
- 6 sites in United States, Canada
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- eSight Corporation
Osteoarthritis
Study of Effectiveness of Hand Exercises to Treat Symptoms of Hand Osteoarthritis
Participants in this study will do hand exercises once per day for 16 weeks. The purpose of the study is to determine if hand exercises designed to improve range of movement and strength are an effective way to decrease…
- Trial name
- NCT00375947
- Testing
- Hand Exercise
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- The Arthritis Research Institute of America
Improvement in Immune Cell Function in Healthy Humans
The Effect of Aged Garlic Extract Supplementation on Immune System
The purpose of this study is to determine whether consuming capsules of aged garlic extract is effective in enhancing function of NK and/or γδ T cell resulting in fewer cold and flu symptoms.
- Trial name
- NCT01390116
- Testing
- Aged garlic extract, AGE
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Florida
Overhead Athletes
Plyometric, Proprioceptive and Strength Exercises in Rugby Players.
Introduction. Shoulder injury is the pathology that causes the longest downtime in rugby players, representing 66% of upper limb injuries in this discipline.
- Trial name
- NCT04254055
- Testing
- exercises
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Investigación en Hemofilia y Fisioterapia