Clinical trials: In Utero Nicotine
Asthma, Pulmonary Function
VCSIP Follow-up Study
The overall aims of this protocol are to determine whether prenatal supplementation with vitamin C to pregnant smokers can improve pulmonary function and decrease wheeze at 5 years of age in their offspring.
- Conditions
- Asthma, Pulmonary Function, Wheezing, In Utero Nicotine
- Trial name
- VCSIPRenewal (NCT03203603)
- Testing
- No active intervention
- Where
- 2 sites in United States
- Volunteers
- 242 people
- Sponsor
- Oregon Health and Science University
Asthma, Wheezing
Vitamin C Supplementation to Pregnant Smokers: Follow-up of 2 Randomized Trials Plus Changes in DNA Methylation
In a randomized clinical trial (RCT) published in JAMA, the investigators have provided evidence that vitamin C supplementation (500 mg daily during pregnancy) ameliorates the effects of maternal smoking during pregnancy on…
- Conditions
- Asthma, Wheezing, In Utero Nicotine, Pulmonary Function
- Trial name
- VCSIP-ECHO (NCT03206710)
- Testing
- No current intervention
- Where
- 2 sites in United States
- Volunteers
- 395 people
- Sponsor
- Oregon Health and Science University
Asthma, Pulmonary Function
Vitamin C to Decrease Effects of Smoking in Pregnancy on Infant Lung Function (VCSIP) Longer Term Follow Up
The overall aims of this protocol are to determine whether prenatal supplementation with vitamin C to pregnant smokers can improve pulmonary function at 10 years of age in their offspring.
- Conditions
- Asthma, Pulmonary Function, Wheezing, In Utero Nicotine
- Trial name
- VCSIP (NCT06106646)
- Testing
- No active intervention in this protocol (previously randomized to Vitamin C)
- Where
- 2 sites in United States
- Volunteers
- 225 people
- Sponsor
- Oregon Health and Science University
Pulmonary Function; Newborn, Abnormal, Infant Wheeze
Vitamin C to Decrease Effects of Smoking in Pregnancy on Infant Lung Function
Vitamin C supplementation (500 mg per day) given to pregnant women who can not quit smoking will improve the pulmonary function tests in their offspring measured at 3 months of age.
- Conditions
- Pulmonary Function; Newborn, Abnormal, Infant Wheeze, In-utero Nicotine, Second Hand Smoke
- Trial name
- VCSIP (NCT01723696)
- Testing
- Vitamin C +prenatal vitamin
- Where
- 2 sites in United States
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University