Clinical trials: In the Perinatal Period
HIV Infections
Effects of Maternal Anti-HIV Treatment on Infants Born to HIV-Infected Women
In clinical trials being conducted throughout the world, pregnant HIV-infected women are given anti-HIV drugs before, during, and after they give birth to prevent mother-to-child transmission of HIV.
- Trial name
- NCT00100867
- Where
- 23 sites in Botswana, Brazil and 6 more
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
Grief, Depressive Symptoms
Impact of a Neonatal-Bereavement-Support DVD on Grief
Experts agree that neonatal death has long-term impact on parents. Many parents experience sadness, pain, anger, bouts of crying, and a depressed mood after the death of a child.
- Trial name
- NCT01926080
- Testing
- DVD Intervention Arm
- Where
- United States
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
HIV Infections
Safety & Immunogenicity of 426c.Mod.Core-C4b Vaccine With 3M-052-AF+Alum in Infants Perinatally Exposed to HIV But Uninfected
The purpose of this study is to evaluate the safety and immunogenicity of 426c.Mod.Core-C4b vaccine adjuvanted with 3M-052-AF + Alum in infants with perinatal HIV exposure who are without HIV at birth
- Trial name
- HVTN316 (NCT06613789)
- Testing
- 426c.Mod.Core-C4b, 3M-052-AF, Aluminum hydroxide suspension (Alum)
- Where
- South Africa
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- HIV Vaccine Trials Network
28 Weeks of Gestation, 18 Years and Over
The Effect of Mindfulness-Based Stress Reduction Programme on Stress, Anxiety, Self-Compassion and Prenatal Attachment
This research will be conducted to examine the effects of a mindfulness-based stress reduction (MBSR) programme on stress, anxiety, self-compassion and prenatal attachment in pregnant women with perinatal loss.
- Trial name
- MBSRASPA (NCT06850701)
- Testing
- mbsr
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Perinatal Depression, Perinatal Anxiety
Cognitive Behavioral Couple Therapy for Perinatal Distress
The hypotheses of the study are There will be differences in perceived perinatal distress, dyadic coping strategies, social support, domains of quality of life, and well-being in couples at Pre- and Post-Test levels during the…
- Trial name
- NCT06001021
- Testing
- Psychopharmacological Intervention, Cognitive Behavioral Couple Therapy, Combination of Psychopharmacological Intervention and CBCT
- Where
- Pakistan
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Sameera Shafiq
Liver Fibrosis
Improved Prevention of Perinatal Hepatitis B Transmission
Impaired activity of Natural Killer (NK) cells has been proposed as a mechanism contributing to viral persistence in Hepatitis C Virus (HCV) infection.
- Trial name
- NCT01133184
- Testing
- Sci B vac
- Where
- Israel
- Volunteers
- 6,343 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Asthma, Dermatitis, Atopic
Impact in Off-spring of Mothers After Perinatal Daily Intake of a Probiotic
A probiotic (Lactobacillus rhamnosus GG) supplement to pregnant women the last four weeks of pregnancy and three months after birth is expected to give a 40% reduction in risk of atopic sensitisation and allergic disease at two…
- Conditions
- Asthma, Dermatitis, Atopic, Rhinitis, Allergic, Perennial
- Trial name
- NCT00159523
- Testing
- Probiotic
- Where
- Norway
- Volunteers
- 416 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Perinatal Depression
A Chinese Version of the Thinking Health Program for East Asian Pregnant Immigrant People in Canada
The goal of this study is to determine the feasibility of using a psychosocial intervention culturally adapted in China to support perinatal mental well-being of Chinese immigrant pregnant women in Canada.
- Trial name
- NCT06446089
- Testing
- THP: cognitive behavior therapy and behavioral activation
- Where
- Canada
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Shahirose Sadrudin Premji
Pregnancy, Birth Weight
Prenatal Multi-micronutrient Supplementation and Pregnancy Outcome
Prenatal maternal micronutrient supplementation has been suggested as a means to reduce the proportion of low birth weight babies in low-income countries.
- Trial name
- NCT00168688
- Testing
- multi micronutrient supplement, MN1, MN2
- Where
- Guinea-Bissau
- Volunteers
- 2,100 people, healthy volunteers welcome
- Sponsor
- Bandim Health Project
Recurrent Miscarriage
Obstetrics , Prenatal Outcomes in Recurrent Miscarriage
The effect of recurrent miscarriage on the outcome of the current pregnancy and if there's a relation between it and adverse out come
- Trial name
- OBPORPL (NCT06356792)
- Where
- Egypt
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Assiut University
Perinatal Depression, PostPartum Depression
Comparing the Effectiveness of Clinicians and Paraprofessionals to Reduce Disparities in Perinatal Depression
There is considerable evidence that most perinatal women at risk for postpartum depression do not engage in mental health services, even when referred by home visiting (HV) programs, primary care physicians, obstetricians, or…
- Trial name
- NCT02979444
- Testing
- Mothers and Babies Groups
- Where
- United States
- Volunteers
- 874 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Maternal Death, Neonatal Death
Evaluating the Effects of SMS Text Messaging Support System Among Frontline Health Workers in Ghana
Introduction Maternal and neonatal mortality continue to be to be prominent public health issues in sub Saharan Africa including Ghana, with slow progress made towards attainment of Millennium Development Goals (MDG) 4 \& 5.
- Conditions
- Maternal Death, Neonatal Death, Postpartum Haemorrhage, Pre-eclampsia
- Trial name
- Accelerate (NCT02468310)
- Testing
- Maternal and neonatal emergency protocols
- Where
- Ghana
- Volunteers
- 65,831 people, healthy volunteers welcome
- Sponsor
- Hannah Brown Amoakoh
Parents, COVID-19 Pandemic
Becoming a Parent During the COVID-19 Pandemic in Austria and Germany
This is an online survey in Austria and Germany directed at parents with children born since the start of the first lockdown of the COVID-19 pandemic (birthdate beginning with 16.03.2020).
- Trial name
- NCT05487105
- Where
- Austria
- Volunteers
- 2,226 people, healthy volunteers welcome
- Sponsor
- University of Salzburg
Depression and Suicide, Mood Disorders
Biological Triggers of Depression in Pregnancy
The goal of the study is to define and measure biological processes that contribute to the underlying pathophysiologic process of peri-partum depression to be used for identifying those at risk for developing it.
- Conditions
- Depression and Suicide, Mood Disorders, Other Perinatal Conditions
- Trial name
- NCT02566980
- Where
- 3 sites in United States
- Volunteers
- 209 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Preterm Pregnancy, Antenatal Corticosteroid
The Effect Of Antenatal Corticosteroids On Early And Late Perinatal Outcomes
In this study, the investigators aims to evaluate whether antenatal corticosteroid administration to women likely to give birth in the late preterm period will reduce early and late neonatal complications and contribute to the…
- Conditions
- Preterm Pregnancy, Antenatal Corticosteroid, Perinatal Problems
- Trial name
- NCT06164080
- Testing
- participants receiving Corticosteroid
- Where
- Turkey (Türkiye)
- Volunteers
- 459 people, healthy volunteers welcome
- Sponsor
- Sanliurfa Mehmet Akif Inan Education and Research Hospital
Perinatal Mental Health, Gestational Weight Gain
Healthy Adaptation to Pregnancy, Postpartum and Parenthood
Healthy Adaptation to Pregnancy, Postpartum and Parenthood (HAP3) The HAP3 study is evaluating a new digital support program for pregnant women and their partners.
- Conditions
- Perinatal Mental Health, Gestational Weight Gain, Postpartum Weight Retention, Child Development
- Trial name
- HAP3 (NCT07837193)
- Testing
- HAP3 Family App
- Where
- Belgium
- Volunteers
- 572 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Fetal Distress
The SBAR Effect on Safety Attitudes in the Perinatal Department
The aim of this study is to analyze the impact of SBAR by the SAQ questionnaire in the perinatal department.
- Trial name
- NCT01570335
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Far Eastern Memorial Hospital
Perinatal Mortality, Cause of Neonatal Death
Verbal Autopsy to Assess Early Neonatal Death and Stillbirth
The NICHD Global Network (GN) for Women's and Children's Health Research, a multi-site, international research network, provides a unique infrastructure to implement an expanded perinatal verbal autopsy study using the FIRST…
- Conditions
- Perinatal Mortality, Cause of Neonatal Death, Cause of Stilbirth
- Trial name
- VA (NCT00640055)
- Testing
- Coordinator, Physician-assigned cause of death
- Where
- 4 sites in Guatemala, Pakistan and 2 more
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- NICHD Global Network for Women's and Children's Health
Maternal Death, Newborn Death
Impact of the Safe Childbirth Checklist in Luapula Province of Zambia Province of Zambia
This study would like to determine if the introduction of the Safe Childbirth Checklist and associated mentorship can improve the adherence of skilled birth attendants (SBAs) to the essential practices of childbirth delivery.
- Trial name
- NCT03263182
- Testing
- Introduction of the Safe Childbirth Checklist
- Where
- 4 sites in Zambia
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Clinton Health Access Initiative Inc.
Perinatal Depression, Parents
Effect of 'Parentbot - a Digital Healthcare Assistant (PDA)' in Improving Parenting Outcomes During the Perinatal Period
The Parentbot - a Digital healthcare Assistant (PDA) is a mobile application-based psychosocial parenting intervention with integrated chatbot features, intended for couples to use during the perinatal period.
- Conditions
- Perinatal Depression, Parents, Self Efficacy, Anxiety
- Trial name
- PDA (NCT05463926)
- Testing
- PDA mobile application
- Where
- Singapore
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- National University of Singapore