Clinical trials: In the Perinatal Period
Hypothermia, Morbidity
Perinatal Hypothermia, Risk Factors and Long-Term Consequences in Guinea-Bissau, Westafrica
Low body temperature (hypothermia (HT)) at birth contributes to infant mortality in low-income countries. A study from Guinéa-Bissau indicates that HT results in an increased mortality rate, which persist at least two months…
- Conditions
- Hypothermia, Morbidity, Mortality
- Trial name
- NCT00429000
- Testing
- thermospot
- Where
- Guinea-Bissau
- Volunteers
- 788 people, healthy volunteers welcome
- Sponsor
- Bandim Health Project
Development, Infant, Perinatal Disorder
Early Childhood : Action Research in the Lunévillois Area (PERL)
The PERL project is a research in prevention in perinatality. The objective of this research is to offer preventive and regular care at familie's home in the Lunévillois area, while integrating it into the existing practices of…
- Trial name
- PERL (NCT03506971)
- Testing
- Psychologist's evaluation, Pediatric Nurse's interventions, Joint home visits
- Where
- France
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Centre Psychothérapique de Nancy
Mental Health, Perinatal Depression
Study of the Intervention Effect of Self-help Training Camps in Promoting Mental Health Among Perinatal Women
This study was a multi-center randomized controlled trial of an Internet-based self-help mental fitness training camp intervention that included women in early, mid, and late pregnancy with or without psychological distress.
- Trial name
- NCT06405932
- Testing
- Mental Fitness Training Camp
- Where
- China
- Volunteers
- 1,691 people, healthy volunteers welcome
- Sponsor
- Fangbiao Tao
Infant, Newborn, Diseases, Sepsis
Prevention of Perinatal Sepsis (PoPS): Evaluation of Chlorhexidine Wipes of Birth Canal and Newborn
The purpose of this study is to evaluate whether use of the disinfectant chlorhexidine administered to the birth canal during labour and newborn at delivery can protect a woman and her baby from bacterial infections after birth.
- Conditions
- Infant, Newborn, Diseases, Sepsis, Puerperal Infection
- Trial name
- NCT00136370
- Testing
- Chlorhexidine, Birth canal wipe, sterile water external genital wipe
- Where
- South Africa
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Perinatal Mental Health Care Practices During the COVID-19 Pandemic
Best Practices in Perinatal Mental Health During COVID-19
The COVID-19 pandemic has caused changes in health care during pregnancy, childbirth and postpartum. Although adverse effects of COVID-19 on perinatal mental health have been documented, changes in the perinatal mental health…
- Trial name
- NCT04779775
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Minho
Perinatal Depression, Postpartum Depression
Integrating Text Messages Into the Mothers and Babies Course
This project is aimed at enhancing the effectiveness and scalability of the Mothers and Babies 1-on-1 Course (MB) among home visiting programs.
- Trial name
- NCT03420755
- Testing
- Mothers and Babies 1-on-1, Mothers and Babies Plus Text
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Postpartum Depression, Perinatal Depression
Maternal Mental Health Access - MaMa
This hybrid effectiveness-implementation project will allow the team to evaluate and refine implementation in preparation for future multisite trials to ultimately move the Evidence-Based Intervention (EBI) to scale among diverse…
- Trial name
- MaMa (NCT06049433)
- Testing
- Maternal Mental Health Access for Postpartum Depression- Prevention and UPLIFT- intervention, On-Demand + Discussion board (DB), Arm 2
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Utah
Maternal and Child Health Outcomes
Moms and Babies Health and Well-being
The goal of this clinical trial is to see how giving direct cash support affects the health of pregnant women and their babies in the U.S.
- Trial name
- MBHW (NCT06923371)
- Testing
- Direct Cash Support for Maternal and Infant Health (High fee), Behavioral: Direct Cash Support for Maternal and Infant Health (Low fee)
- Where
- United States
- Volunteers
- 1,250 people, healthy volunteers welcome
- Sponsor
- Columbia University
Depression, Postpartum, Puerperal Disorders
Screening for Depression and Anxiety in Pregnant and Postpartum Women: Evaluating Prevalence, Risk Factors, and the Stepped Screening Protocol in a Care Pathway
Having a baby is a major life event, and for some women, it can increase the risk of developing mental health issues. A recent survey in the UK found that one in five women experience mental health problems during pregnancy or…
- Conditions
- Depression, Postpartum, Puerperal Disorders, Depression During Pregnancy, Anxiety
- Trial name
- NCT06664593
- Testing
- integrated perinatal mental health pathway
- Where
- Belgium
- Volunteers
- 378 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Abortion, Spontaneous, Abortion, Habitual
RPL: Interval to Live Birth and Adverse Perinatal Outcomes
This will be a retrospective observational cohort study utilizing the data from the British Columbia Perinatal Data Registry (BCPDR).
- Conditions
- Abortion, Spontaneous, Abortion, Habitual, Birth Intervals, Pregnancy Loss
- Trial name
- NCT04360564
- Testing
- Recurrent pregnancy loss
- Where
- Canada
- Volunteers
- 140,000 people, healthy volunteers welcome
- Sponsor
- Children's & Women's Health Centre of British Columbia
Depression, Depression, Postpartum
TrueBlue Clinical Study - Investigating the Use of a Mobile Phone App TrueBlue for Monitoring Depression and Anxiety
This trial will assess the safety, feasibility, acceptability, usability and agreement with validated scales of an automated mood monitoring App (TrueBlue), in adult, perinatal participants (recruited between 12 weeks of…
- Conditions
- Depression, Depression, Postpartum, Anxiety in Pregnancy, Anxiety
- Trial name
- NCT06364488
- Testing
- TrueBlue App
- Where
- 2 sites in United Kingdom
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- BlueSkeye AI
Psychological Well-being, Childbirth
The Effect of Trauma Informed Care in Childbirth
The aim of this study is to determine the effect of supportive care based on trauma informed care during childbirth on perinatal mental health outcomes.
- Conditions
- Psychological Well-being, Childbirth, Care Pattern, Maternal
- Trial name
- NCT05662176
- Testing
- Experimental: Supportive Care based on trauma informed care, Standart care
- Where
- Turkey (Türkiye)
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Mersin University
Pain
The Maternal and Perinatal Outcomes Associated With the Use of Non-pharmacological in Labor
Although there are studies that investigated the use of non-pharmacological pain relief and correction of dystocia during labor, there are few randomized controlled trials, especially related to combined protocols that use such…
- Trial name
- NCT01601860
- Testing
- Use of non-pharmacological, Other: Routine care
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Infant, Premature, Erythropoietin
High-Dose Erythropoietin in Extremely Premature Infants to Prevent/Attenuate Brain Injury: A Phase II Study
The highest risk for perinatal brain injury occurs among extremely premature infants who weigh less than 1250 grams at birth. Such perinatal brain injury is currently irreversible, associated with neurodevelopmental disability…
- Conditions
- Infant, Premature, Erythropoietin, Brain Injury, Intraventricular Hemorrhage
- Trial name
- NCT00589953
- Testing
- Erythropoietin
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Atlantic Health System
Preterm Birth
Cerclage for the Reduction of Extreme Preterm Birth in Twin Pregnancies With a Short Cervix or Dilatation
The goal of this clinical trial is to assess the effectiveness of a cerclage in women with a twin pregnancy with a midpregnancy short cervix or cervical dilatation compared to standard treatment (no cerclage) in the prevention of…
- Trial name
- TWIN Cerclage (NCT05968794)
- Testing
- Vaginal cerclage
- Where
- 13 sites in Belgium, Netherlands
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Fetal Growth Restriction, Perinatal Outcome
Relationship of DV Doppler Parameters to Perinatal Outcomes in IUGR vs Non-IUGR
This observational study investigates whether blood flow in the ductus venosus, a small fetal vein measured by Doppler ultrasound, is related to pregnancy outcomes.
- Conditions
- Fetal Growth Restriction, Perinatal Outcome, Pregnancy, High Risk
- Trial name
- DV-FGR (NCT07190157)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Izmir City Hospital
Simulation-based Learning, Communication Skills
Therapeutic Communication Training in Perinatal Loss: Simulation-Based Approaches
This study aims to evaluate the effect of simulation-based education on nursing students' therapeutic communication skills in managing perinatal loss.
- Conditions
- Simulation-based Learning, Communication Skills, Paper-Pencil Simulation, High-fidelity Simulation
- Trial name
- NCT06959875
- Testing
- High-Fidelity Simulation-Based Therapeutic Communication Training, Paper-Pencil Simulation-Based Therapeutic Communication Training
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Perinatal Depression, Chronic Pain
CSF/Serum Biomarkers in Predicting PND/Persistent Pain After Cesarean
The aim is to investigate if inflammatory biomarkers in the blood and cerebrospinal fluid (CSF) are associated with the development of perinatal depression and/or persistent pain after cesarean delivery.
- Trial name
- NCT04271072
- Testing
- No intervention
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Duke University
Cicatrix
Perinatal Tissue Mesenchyme Stem Cells in the Treatment for Caesarean Section Scars
The study is to investigate the efficacy and safety of perinatal tissue mesenchyme stem cells treatment on the appearance of a caesarean scar as compared to a similar untreated scar.
- Trial name
- NCT02772289
- Testing
- Mesenchyme Stem Cells low-dose group, Mesenchyme Stem Cells high-dose group
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Maternal and Child Health Hospital of Foshan
Intimate Partner Violence
Domestic Violence Enhanced Perinatal Care Program in China
The proposed project addresses intimate partner violence (IPV) against pregnant women, which is a serious social and health issue.
- Trial name
- NCT05388565
- Testing
- Domestic Violence Enhanced Perinatal Care Program, Standard of Care
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin