Clinical trials: In-Hospital Cardiac Arrest
Cardiac Arrest
Packed Red Blood Cell Transfusion During Cardiac Arrest
The purpose of this pilot interventional study is to collect preliminary data on administering packed red blood cell (PRBC) during cardiac arrest (CA).
- Trial name
- NCT06462027
- Testing
- Packed Red Blood Cells (1 unit), Packed Red Blood Cells (2 units), Saline
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- NYU Langone Health
Ventricular Arrhythmias and Cardiac Arrest
Prophylactic Anti-aRrhythmic Therapy With Amiodarone in Critically Ill Patients Admitted for an Out-of-hospital Cardiac Arrest With Initial Shockable Rhythm
To determine if prophylactic administration of amiodarone for 72 hours in critically ill patients admitted after an OHCA with shockable rhythm, with a confirmed or a presumed cardiac cause, decreases the incidence of a composite…
- Trial name
- PARACA (NCT06835491)
- Testing
- Amiodarone
- Where
- 29 sites in France
- Volunteers
- 674 people
- Sponsor
- Versailles Hospital
Heart Arrest
Clinical Validation of Vital-PICASO for Predicting Cardiac Arrest Within 24 Hours
The purpose of this retrospective study is to evaluate the clinical performance of Vital-PICASO, an artificial intelligence-based biological signal analysis software designed to predict the risk of in-hospital cardiac arrest…
- Trial name
- NCT07742943
- Where
- South Korea
- Volunteers
- 387 people
- Sponsor
- Huinno AIM
Out-of-Hospital Cardiac Arrest, Post Cardiac Arrest Syndrome
The Complement Lectin Pathway After Cardiac Arrest
This study includes comatose survivors of out-of-hospital cardiac arrest treated with 24 hours or 48 hours of targeted temperature management.
- Trial name
- NCT02826057
- Testing
- Targeted temperature management (33 degree Celsius)
- Where
- 3 sites in Denmark
- Volunteers
- 82 people
- Sponsor
- University of Aarhus
Heart Arrest, Out-Of-Hospital, Hypoxia-Ischemia, Brain
Neuropsychological Outcome After Cardiac Arrest
This study is a sub-study to the large pragmatic Target Temperature Management 2 Trial (TTM2-trial, ClinicalTrials.gov Identifier: NCT02908308), assessing effectiveness of controlled hypothermia after out-of-hospital cardiac…
- Conditions
- Heart Arrest, Out-Of-Hospital, Hypoxia-Ischemia, Brain, Cognition Disorders, Psychological Distress
- Trial name
- NCT03543371
- Testing
- Neuropsychological assessment
- Where
- 8 sites in Denmark, Sweden and 1 more
- Volunteers
- 200 people
- Sponsor
- Region Skane
Inhospital Cardiac Arrest
Neurological Outcomes After In-Hospital Cardiac Arrest
Little is known about the long-term neurological outcomes after in-hospital cardiac arrest (IHCA). It is also not known whether withdrawal of life-sustaining measures will influence rates of survivors with poor neurological…
- Trial name
- NO-IHCA (NCT03006484)
- Testing
- No intervention
- Where
- South Korea
- Volunteers
- 322 people
- Sponsor
- Asan Medical Center
Out of Hospital Cardiac Arrest
Initiation of Cooling by EMS to Promote Adoption of In-hospital Hypothermia in Cardiac Arrest Survivors
This is a large pragmatic, randomized controlled trial comparing pre-hospital initiation of therapeutic hypothermia by Emergency Medical Services (EMS) providers to conventional post-resuscitation care.
- Trial name
- NCT01528475
- Testing
- Pre-hospital cooling
- Where
- 3 sites in Canada
- Volunteers
- 585 people
- Sponsor
- Sunnybrook Health Sciences Centre
Out of Hospital Cardiac Arrest
Cardiac Catheterization in Cardiac Arrest
This is a pilot study that will lead to a large randomized control trial (RCT), to assess whether early versus late or no cardiac catheterization is associated with improved outcomes in out-of-hospital cardiac arrest (OHCA)…
- Trial name
- NCT02587494
- Testing
- Cardiac catheterization
- Where
- Canada
- Volunteers
- 75 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Bystander, Chest Compression
REsuscitation Survey of Police Officers in New Taipei City for Duty
Out-of-hospital cardiac arrest (OHCA) remains a time-critical emergency where early cardiopulmonary resuscitation (CPR) and timely defibrillation using an automated external defibrillator (AED) are key to improving survival and…
- Conditions
- Bystander, Chest Compression, Out of Hospital Cardiac Arrest, AED
- Trial name
- RESPOND (NCT06955351)
- Testing
- Survey by Questionnaire
- Where
- Taiwan
- Volunteers
- 4,867 people, healthy volunteers welcome
- Sponsor
- Far Eastern Memorial Hospital
In-Hospital Cardiac Arrest
Derivation of An In-Hospital Cardiac Arrest Prediction Model for Patients in Intensive Care Unit
Current studies have shown that hospitalized ICU patients have a high risk of IHCA, with an incidence of about 0.6-7.8%. Early prediction of the occurrence of IHCA in severe patients can provide early intervention, prevent the…
- Trial name
- NCT04670458
- Testing
- no intervention
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Qilu Hospital of Shandong University
Brain Injuries, Traumatic, Brain Injuries, Acute
Critical Hyperacute Assessment Research On Neurobiomarker Kinetics in Acute Brain Injury
Traumatic brain injury (TBI) and other conditions that reduce blood flow to the brain - such as cardiac arrest (CA) - are life-threatening medical emergencies.
- Conditions
- Brain Injuries, Traumatic, Brain Injuries, Acute, Hypoxia, Brain, Cardiac Arrest (CA)
- Trial name
- CHARON (NCT07782216)
- Where
- 4 sites in Hungary
- Volunteers
- 477 people
- Sponsor
- University of Pecs
Out-Of-Hospital Cardiac Arrest, Advanced Cardiac Life Support
Cardiac Arrest and Ventilation Method
Comparison of Manual Ventilation and Automatic Mechanical Ventilation during CPR, Pilot \& Feasibility Study (CAVE-I trial)
- Conditions
- Out-Of-Hospital Cardiac Arrest, Advanced Cardiac Life Support, Ventilation
- Trial name
- NCT05550454
- Testing
- Automatic Mechanical Ventilation, Manual Ventilation
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Seoul National University Hospital
Out of Hospital Cardiac Arrest, Computed Tomography
Timing for Computed Tomography and Post-Resuscitation Care on Short-Term Outcomes in Out-of-Hospital Cardiac Arrest
This retrospective multicenter study investigates the association between the timing of computed tomography (CT) scans and short-term outcomes in adult non-traumatic out-of-hospital cardiac arrest (OHCA) patients who achieved…
- Trial name
- NCT06936917
- Volunteers
- 5,000 people
- Sponsor
- National Taiwan University Hospital
Out-Of-Hospital Cardiac Arrest, Myocardial Infarction
Factors Associated With CPC 1-2 in 110 Patients Admitted in French ICU for a Myocardial Infarction Complicated by an OHCA.
This study evaluate the association of some in-ICU factors with the neurological prognosis of patients admitted for an out-of-hospital cardiac arrest due to a myocardial infarction.
- Conditions
- Out-Of-Hospital Cardiac Arrest, Myocardial Infarction, Coma, Outcome, Fatal
- Trial name
- ACR-MI (NCT04584463)
- Volunteers
- 110 people
- Sponsor
- Central Hospital, Nancy, France
Cardiac Arrest
Respiratory Parameters Using Advanced Airways During In-hospital Cardiac Arrest
The investigators aim to investigate the real life volumes of air delivered to the lungs when rescuers deliver these breaths by hand as part of resuscitation attempts during cardiac arrest.
- Trial name
- NCT06580652
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Royal United Hospitals Bath NHS Foundation Trust
Out of Hospital Cardiac Arrest
Pre-hospital ECMO or Conventional Resuscitation for Refractory Cardiac Arrest
This pilot study aims to determine feasibility of randomising patients to receive pre-hospital Extracorporeal Cardiopulmonary Resuscitation (ECPR) compared to conventional cardiac arrest care for refractory out of hospital…
- Trial name
- PACER (NCT06177730)
- Testing
- Pre-Hospital ECPR
- Volunteers
- 10 people
- Sponsor
- Australian and New Zealand Intensive Care Research Centre
Heart Arrest, Out-Of-Hospital, Physical Activity
Physical Activity After Cardiac Arrest; a Sub-study in the Target Temperature Management Trial 2
The Target Temperature Management trial 2 (TTM2) is an international multi-center study, that randomize patients with OHCA of a presumed cardiac or unknown cause to target temperature management at 33°C or normothermia but…
- Trial name
- NCT03543332
- Testing
- Measures of physical activity and kinesiophobia
- Where
- 8 sites in Denmark, Sweden and 1 more
- Volunteers
- 109 people
- Sponsor
- Region Skane
Heart Arrest, Out-of-hospital Cardiac Arrest
Cognitive Impairment Following Cardiac Arrest and Target Temperature Management
This is a steering group approved substudy to the Target Temperature Management trial (TTM, ClinicalTrials.gov Identifier: NCT01020916).
- Conditions
- Heart Arrest, Out-of-hospital Cardiac Arrest, Cognition Disorders, Brain Injury
- Trial name
- NCT01946932
- Testing
- Temperature treatment
- Where
- 20 sites in Denmark, Italy and 3 more
- Volunteers
- 287 people
- Sponsor
- Region Skane
Acute Coronary Syndrome Without ST Elevation on Electrocardiogram, Acute Coronary Syndromes (ACS)
Occurrence of Severe Cardiac Rhythm and Conduction Disturbances in Emergency Department Patients With Non-ST Elevation Acute Coronary Syndrome
Cardiovascular diseases are the leading cause of death worldwide. Among them, coronary artery disease-especially in its acute form, known as acute coronary syndrome (ACS)-is the most frequent cause of cardiovascular death.
- Conditions
- Acute Coronary Syndrome Without ST Elevation on Electrocardiogram, Acute Coronary Syndromes (ACS), Myocardial Infarction, Unstable Angina Pectoris, Sudden Cardiac Death, Stroke, Peripheral Artery Disease
- Trial name
- SurvSCA (NCT07112547)
- Where
- 10 sites in France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Strasbourg, France
Cardiopulmonary Arrest, Cardiopulmonary Resuscitation
Compression Feedback for Patients With In-hospital Cardiac Arrest
A prospective, randomized, controlled, parallel study was conducted in patients undergoing resuscitation with chest compression for in-hospital cardiac arrest (IHCA) in the mixed medical-surgical ICU's of 8 academic tertiary care…
- Trial name
- CFA (NCT02845011)
- Testing
- Audiovisual compression feedback, Standard Manual Chest Compression
- Volunteers
- 900 people
- Sponsor
- Baqiyatallah Medical Sciences University