Clinical trials: In-Hospital Cardiac Arrest
Echocardiography, Transesophageal, In-hospital Cardiac Arrest
RescueTEE for In-hospital Cardiac Arrest (ReTEECA Trial)
ReTEECA Trial. Rescue TransEsophageal Echocardiography for In-Hospital Cardiac Arrest. This trial is aimed at studying the utility and interventional outcomes of rescue transesophageal echocardiography (RescueTEE) to aid in…
- Conditions
- Echocardiography, Transesophageal, In-hospital Cardiac Arrest, Cardiac Arrest, Cardiopulmonary Arrest With Successful Resuscitation
- Trial name
- ReTEECA (NCT04220619)
- Testing
- Tranesophageal Echocardiography
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Heart Arrest, Out-Of-Hospital
Calcium for Out-of-Hospital Cardiac Arrest
This is an investigator-initiated, multicenter, randomized, placebo-controlled, parallel group, double-blind, superiority trial of calcium during adult out-of-hospital cardiac arrest.
- Trial name
- COCA (NCT04153435)
- Testing
- Calcium Chloride, Sodium chloride 0.9%
- Where
- Denmark
- Volunteers
- 397 people
- Sponsor
- Lars Wiuff Andersen
Out-of-hospital Cardiac Arrest
Epidemiological Study on the Management of Out-of-hospital Cardiac Arrest Survivors in Champagne ArDEnnes
Out-of-hospital cardiac arrest (OHCA) is a public health problem, affecting 50,000 people per year in France. Intervention time (initiation of cardiopulmonary resuscitation (CPR) and advanced CPR) are associated with a better…
- Trial name
- CASCADE (NCT04993716)
- Testing
- observational
- Where
- France
- Volunteers
- 294 people
- Sponsor
- Stephane Sanchez
Out-Of-Hospital Cardiac Arrest
The Impact of Aortic Valve Compression During Cardio-pulmonary Resuscitation on Patients With Out-of-hospital Cardiac Arrest
Purpose: This study aims to find out if the current way of performing chest compressions during resuscitation for patients who have suffered a cardiac arrest outside of the hospital is affecting their chances of recovery.
- Trial name
- AVC in OHCA (NCT05932784)
- Testing
- transesophageal echocardiography
- Where
- Taiwan
- Volunteers
- 76 people
- Sponsor
- Far Eastern Memorial Hospital
Heart Arrest
BC ECPR Trial for Out-of-Hospital Cardiac Arrest
The addition of an Extracorporeal-Cardiopulmonary Resuscitation (ECPR) service to a region may improve the survival of young patients with sudden unexpected cardiac arrest.The primary aim of this study is to determine the benefit…
- Trial name
- NCT02832752
- Testing
- ECPR Protocol
- Where
- 3 sites in Canada
- Volunteers
- 308 people
- Sponsor
- University of British Columbia
Cardiac Arrest, Resuscitation
Mechanical Versus Manual Cardiopulmonary Resuscitation
In this study, the investigators compared mechanical and manual chest compressions in in-hospital cardiac arrest cases.
- Trial name
- NCT04422938
- Testing
- Manuel chest compressions handled by clinicians, LUCAS™ 2 Chest Compression System
- Where
- Turkey (Türkiye)
- Volunteers
- 303 people
- Sponsor
- Ankara City Hospital Bilkent
Cardiac Arrest, Pulseless Electrical Activity
Surviving PEA in Roanoke (SPEAR) Study
The Carilion Clinic and Virginia Tech Carilion School of Medicine, in conjunction with Roanoke Fire-EMS, Botetourt County Department of Fire \& EMS and Salem Fire-EMS, are studying the outcomes of patients experiencing Pulseless…
- Trial name
- SPEAR (NCT05283850)
- Testing
- High Calcium, Low Sodium (HCLS) Crystalloid Therapy, High Calcium, High Sodium (HCHS) Crystalloid Therapy
- Where
- United States
- Volunteers
- 342 people
- Sponsor
- Carol Bernier
Out-Of-Hospital Cardiac Arrest
Enhanced Community First Responder System Evaluation in Singapore
The rise in out-of-hospital cardiac arrest (OHCA) cases in Singapore highlights the need for effective bystander cardiopulmonary resuscitation (BCPR).
- Trial name
- TCPR-Link (NCT06530433)
- Testing
- CPRCard + TCPR Link App and Web, CPRCard Only
- Where
- Singapore
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Singapore General Hospital
Cardiac Arrest, Out-Of-Hospital
Gathering Evidence on Best Practices for Lay Rescuer CPR Training
The goal of this prospective trial is to compare CPR skill and attitudes in lay rescuers. The main question[s] it aims to answer are: What is the optimal training timing, duration, and frequency for lay rescuers that leads to CPR…
- Trial name
- NCT05908500
- Testing
- CPR Training, CPR Manikin Type
- Where
- United States
- Volunteers
- 2,100 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Reno
Cardiac Arrest
Comparison on the Efficacy of a Monophasic
The central purpose of this study is to compare the clinical outcomes of patients who suffered a cardiac arrest while hospitalized at the VA and were resuscitated after biphasic defibrillators were implemented in 2001 to clinical…
- Trial name
- AED (NCT00472498)
- Volunteers
- 95 people
- Sponsor
- Emory University
Cardiac Arrest, Out-Of-Hospital Cardiac Arrest
The Effect of Prehospital Combination of Epinephrine, Vasopressin, and Steroid in OHCA
This project is a randomized controlled clinical research design, The hypothesis P-I-C-O of the study is: For adult patients in the Taipei City and New Taipei City communities who have suffered sudden non-traumatic death and have…
- Conditions
- Cardiac Arrest, Out-Of-Hospital Cardiac Arrest, Emergency Medical Services
- Trial name
- REVIVES (NCT06203847)
- Testing
- Combination group, Standard group
- Where
- Taiwan
- Volunteers
- 1,344 people
- Sponsor
- National Taiwan University Hospital
Cardiac Arrest
Head-up Position and High Quality Cardiopulmonary Resuscitation in OHCA
Elevation of the head and thorax, also known as Head-up cardiopulmonary resuscitation (HUP CPR), has been studied extensively in pigs in ventricular fibrillation (VF).
- Trial name
- GRAVITY (NCT03996616)
- Testing
- Head UP Position, Impedance Threshold Device, New Automated CPR
- Where
- 2 sites in France
- Volunteers
- 126 people
- Sponsor
- University Hospital, Grenoble
Cardiac Arrest
Code Blue Outcomes & Process Improvement Through Leadership Optimization Using Teleintensivists-Simulation
This multicenter randomized trial will employ in-situ cardiac arrest simulations ("mock codes") to test whether using telemedicine technology to add an intensive care physician as the "copilot" for cardiac arrest resuscitation…
- Trial name
- COPILOT-Sim (NCT03000829)
- Testing
- Tele-intensivist consultation, Simulated "observation" by ICU physician
- Where
- 7 sites in United States
- Volunteers
- 1,001 people
- Sponsor
- Intermountain Health Care, Inc.
Out-Of-Hospital Cardiac Arrest, Post Cardiac Arrest Syndrome
Pre-hospital Post ROSC Care: Are we Achieving Our Targets?
Rational: Out of hospital cardiac arrest is a devastating event with a high mortality. Survival rates have increased over the last years, with the availability of AED's and public BLS.
- Conditions
- Out-Of-Hospital Cardiac Arrest, Post Cardiac Arrest Syndrome, Emergency Medical Services
- Trial name
- POP-ROC (NCT04339257)
- Volunteers
- 175 people
- Sponsor
- University Medical Center Groningen
Out-of-hospital Cardiac Arrest (OHCA), ECMO Treatment
Hypothermia Versus Normothermia After Extracorporeal Cardiopulmonary Resuscitation for Out-of-hospital Cardiac Arrest
The SAVE-J NEUROTHERM trial is a cluster randomized trial that evaluated and compared the mortality risk, neurological outcomes, and adverse events between patients who underwent hypothermia and those who underwent normothermia…
- Conditions
- Out-of-hospital Cardiac Arrest (OHCA), ECMO Treatment, Temperature, Post Cardiac Arrest Syndrome
- Trial name
- J-NEURO (NCT06776549)
- Testing
- Temperature control
- Where
- 29 sites in Japan
- Volunteers
- 468 people
- Sponsor
- Kagawa University
Cardiac Arrest, Neurological Injury
Lactate in Cardiac Arrest
Blood lactate levels will be measured using a simple handheld device at time of return of spontaneous circulation (ROSC) following out of hospital cardiac arrest (OHCA).
- Trial name
- NCT02352350
- Testing
- Blood Lactate Levels, Neurological Outcomes
- Sponsor
- University of Florida
Cardiac Arrest, Out-Of-Hospital, Ventricular Fibrillation
Ventricular Fibrillation Following Out-of-hospital Cardiac Arrest
The majority of survivors suffering an out-of-hospital cardiac arrest (OHCA) are those who initially present with a shockable rhythm, which is usually ventricular fibrillation (VF).
- Trial name
- NCT05325385
- Testing
- There are no interventions - this is a database study only
- Where
- United Kingdom
- Volunteers
- 15,000 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Out-of-hospital Cardiac Arrest (OHCA)
Resuscitation Enhancement to Avoid Rearrest Through Evidence-based Strategies in Prehospital Post-resuscitation Care
Out-of-hospital cardiac arrest (OHCA) remains a leading global emergency condition with low survival to hospital discharge despite advances in cardiopulmonary resuscitation.
- Trial name
- RE-ARREST (NCT07239908)
- Testing
- Prehospital post cardiac arrest care protocol
- Where
- Thailand
- Volunteers
- 318 people
- Sponsor
- Siriraj Hospital
Out-Of-Hospital Cardiac Arrest
EXecution of Trans-Esophagus Echo Cardiogram in CardioPulmonary Resuscitation for Patients With Out-of-hospital Cardiac Arrest
The purpose of this single center, randomized clinical control trial is to determine that changing chest compression site during cardiopulmonary resuscitation according to the examination of the TEE could increase the level of…
- Trial name
- EXECT_CPR (NCT05907460)
- Testing
- transesophageal echocardiography examination during cardiopulmonary resuscitation
- Where
- Taiwan
- Volunteers
- 132 people
- Sponsor
- Far Eastern Memorial Hospital
Cardiac Arrest
Prehospital Cerebral Oxygenation During Cardiopulmonary Resuscitation (CPR)
Near infrared spectroscopy (NIRS) is a technique that measures regional cerebral oxygenation in a non-invasive manner. Through the use of near infrared light, the difference between oxygenated and deoxygenated hemoglobin can be…
- Trial name
- NCT01806844
- Where
- 5 sites in Belgium
- Volunteers
- 200 people
- Sponsor
- Hasselt University