Clinical trials: In-Hospital Cardiac Arrest
Out-of-hospital Cardiac Arrest
Digestive ENdoscopy afTeR Out-of-hospitAl Cardiac arresT
Post-cardiac arrest ischemia/reperfusion phenomenon led to organs injury and failure. Among the different organs, gastro-intestinal tract injury could contribute to post-cardiac arrest shock.
- Trial name
- ENTRACT (NCT02349074)
- Testing
- Digestive endoscopy
- Where
- 9 sites in Belgium, France
- Volunteers
- 221 people
- Sponsor
- Versailles Hospital
Acute Coronary Syndromes (ACS), Ventricular Tachycardia (VT)
Analysis of Life-threatening ARrhythMias After Acute Coronary Syndrome
Patients admitted with an acute coronary syndrome (ACS) are at increased risk of malignant cardiac arrhythmias (MA), such as sustained ventricular tachycardia and ventricular fibrillation.
- Conditions
- Acute Coronary Syndromes (ACS), Ventricular Tachycardia (VT), Ventricular Fibrillation, Pulseless Electrical Activity
- Trial name
- ALARM-ACS (NCT07824050)
- Where
- Netherlands
- Volunteers
- 2,775 people
- Sponsor
- Catharina Ziekenhuis Eindhoven
Out of Hospital Cardiac Arrest
Ambulance Clinicians' Experiences of Attending OHCA in Children
This research will explore ambulance clinicians' experiences of attending out of hospital cardiac arrest (OHCA) incidents involving children. OHCA occurs when the heart stops beating.
- Trial name
- NCT06922019
- Where
- United Kingdom
- Volunteers
- 2,137 people, healthy volunteers welcome
- Sponsor
- University of Warwick
Out-of-hospital Cardiac Arrest
Prophylactic Antibiotics in Comatose Survivors of Out-of-hospital Cardiac Arrest
The purpose of this study is to determine whether there is potential benefits of prophylactic antibiotic treatment in comatose survivors of out-of-hospital cardiac arrest (OHCA) treated in intensive care unit with therapeutic…
- Trial name
- NCT02899507
- Testing
- Amoxicillin-Clavulanic acid
- Where
- Slovenia
- Volunteers
- 60 people
- Sponsor
- University Medical Centre Ljubljana
Cardiac Arrest
Epidemiology and Cost-effectiveness of Out-Of-Hospital Cardiac Arrest in Finland
Observational study of all out-of-hospital cardiac arrest during 6 months in regional areas of Helsinki University Hospital and Kuopio University Hospital from activation of EMS system until follow up to 6 months of…
- Trial name
- FINNRESUSCI (NCT01295424)
- Testing
- No intervention
- Where
- Finland
- Volunteers
- 2,600 people
- Sponsor
- Kuopio University Hospital
Out of Hospital Cardiac Arrest, Stent Thrombosis
Definite Stent Thrombosis in Comatose Out of Hospital Cardiac Arrest Survivors
Reliable data on stent thrombosis (ST) in comatose out of hospital cardiac arrest (OHCA) survivors is lacking. In comatose OHCA survivors suspicion of ST can be made with precise clinical monitoring of the patient with definite…
- Conditions
- Out of Hospital Cardiac Arrest, Stent Thrombosis, Drug Eluting Stent, Therapeutic Hypothermia
- Trial name
- ST OHCA (NCT03312296)
- Where
- Slovenia
- Volunteers
- 151 people
- Sponsor
- University Medical Centre Ljubljana
Out-Of-Hospital Cardiac Arrest
Feasibility and Safety of Delivering a Ketone Drink to Comatose Survivors of Out-of-hospital Cardiac Arrest
Every year, efforts are made to resuscitate about 30,000 people when their hearts stop outside of the hospital environment ('out-of-hospital cardiac arrest').
- Trial name
- NCT03226197
- Testing
- Ketone ester drink
- Where
- United Kingdom
- Volunteers
- 5 people
- Sponsor
- Barts & The London NHS Trust
Cardiac Arrest
RACE-CARS - RAndomized Cluster Evaluation of Cardiac ARrest Systems
RACE-CARS is a real-world cluster-randomized trial designed to evaluate a multifaceted community and health systems intervention aimed to improve outcomes of out-of-hospital cardiac arrest.
- Trial name
- NCT04660526
- Testing
- Rapid cardiac arrest recognition that triggers immediate priority EMS/first responder dispatch by 911 operators, Systematic bystander resuscitation instruction by 911 operators, Comprehensive community training of lay people in CPR and AED use.
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- Duke University
Cardiac Arrest
Comparison on the Efficacy of a Monophasic
The central purpose of this study is to compare the clinical outcomes of patients who suffered a cardiac arrest while hospitalized at the VA and were resuscitated after biphasic defibrillators were implemented in 2001 to clinical…
- Trial name
- AED (NCT00472498)
- Volunteers
- 95 people
- Sponsor
- Emory University
Ventricular Fibrillation, Cardiac Arrest
SmartCPR Trial: An Analysis of a Waveform-Based Automated External Defibrillation (AED) Algorithm on Survival From Out-of-Hospital Ventricular Fibrillation
This study is designed to examine the impact of an available technology within an automated external defibrillator (AEDs) to improve survival following out-of-hospital cardiac arrest for patients presenting in ventricular…
- Trial name
- SmartCPR (NCT00535106)
- Testing
- Automated external defibrillator (Philips FR2+ AED), SmartCPR, Delayed defibrillation
- Where
- 2 sites in United States, United Kingdom
- Volunteers
- 900 people
- Sponsor
- New York City Fire Department
Out-Of-Hospital Cardiac Arrest, Emergencies
Livestreaming From Smartphones as a Supplement to Emergency Calls
The aim of the study is to analyse if live video as a supplement to emergency calls can improve medical dispatchers' situation awareness and enhance the assistance they provide including provision of pre-hospital resources.
- Conditions
- Out-Of-Hospital Cardiac Arrest, Emergencies, Unconscious
- Trial name
- NCT04061187
- Where
- Denmark
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Emergency Medical Services, Capital Region, Denmark
Out-Of-Hospital Cardiac Arrest
International Termination of Resuscitation Practices
Neither the international nor the interregional variation in survival following OHCA is fully understood, but may rely on multiple factors such as: organization of the Emergency Medical Service (EMS) system bystander…
- Trial name
- NCT05029180
- Testing
- Termination of resuscitation
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Sars-CoV2, Covid-19
Cardiac Arrest Incidence and Outcome Among Patients With COVID-19 in French ICUs
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the novel coronavirus disease 2019 (COVID-19) pandemic.
- Trial name
- ACICOVID (NCT04373759)
- Testing
- Cardiopulmonary resuscitation, Modified Rankin score
- Where
- 36 sites in France, Martinique
- Volunteers
- 186 people
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Out-of-hospital Cardiac Arrest
Application of Mechanical Cardiopulmonary Resuscitation Devices and Their Value in Out-of-hospital Cardiac Arrest: A Retrospective Analysis of the German Resuscitation Registry
The aim of this study was to analyse a large CPR database, the German Resuscitation Registry, to evaluate potential benefits of mechanical CPR devices over manual CPR in adult cardiac arrest victims.
- Trial name
- NCT02932124
- Testing
- mechanical chest compression device
- Volunteers
- 19,609 people
- Sponsor
- German Resuscitation Registry
Out-Of-Hospital Cardiac Arrest
Automatic Ventilation in Prehospital Resuscitation on OHCA
The goal of this randomized controlled trial is to compare prehospital ventilation strategies in out-of-hospital cardiac arrest. The intervention group is automatic ventilation and the control group is manual ventilation.
- Trial name
- NCT06067204
- Testing
- Automatic ventilation, Manual ventilation
- Where
- Taiwan
- Volunteers
- 522 people
- Sponsor
- National Taiwan University Hospital
Cardiogenic Shock, Malignant Arrhythmias
The Caribbean Registry of Extracorporeal Membrane Oxygenation (ECMO) From the University Hospital in Martinique
The project's main goal is to collect baseline clinical and procedural data as well as to assess clinical outcomes for all patients undergoing VV, VA or VAV ECMO implantation in the French West Indies and Guiana.
- Conditions
- Cardiogenic Shock, Malignant Arrhythmias, Ischemic or Valvular Heart Failure, Drepanocytosis and Thoracic Syndrome
- Trial name
- NCT07351435
- Volunteers
- 1,200 people
- Sponsor
- University of Genova
Cardiac Arrest, Cardiopulmonary Resuscitation
Quantitative Measurement of Cardiopulmonary Resuscitation (CPR) During In Hospital Cardiac Arrest
The design of this protocol is a prospective observational study to objectively measure the rate, depth and quality of chest compressions and ventilations delivered during cardiac arrest in the Pediatric Intensive Care Unit…
- Trial name
- Q-CPR (NCT00628693)
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- Children's Hospital of Philadelphia
Cardiac Arrest
Assessing CPR Quality During In-Hospital Cardiac Arrest
Using an investigational monitor/defibrillator that passively records CPR quality parameters, including chest compression rate and depth and ventilation rate and volume, we are prospectively recording CPR quality during…
- Trial name
- NCT00228293
- Testing
- investigational monitor/defibrillator with CPR feedback
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Chicago
Out-Of-Hospital Cardiac Arrest, In-hospital Cardiac Arrest
RIAC - Registro Italiano Arresti Cardiaci (Italian Registry of Cardiac Arrest)
RIAC - An Observational, Prospective, Multi-centre, Study of Epidemiology, Treatment, and Outcome of Cardiac Arrest in Italy.
- Trial name
- RIAC (NCT03220269)
- Testing
- Out-of-hospital cardiac arrest (OHCA), In-hospital cardiac arrest (IHCA)
- Where
- Italy
- Volunteers
- 8,000 people
- Sponsor
- Italian Resuscitation Council
Cardiac Arrest
Multifaceted Intervention for Increasing Performance of CPR by Laypersons in Out-of-hospital Cardiac Arrest
Cardiac arrest (CA) early recognition is essential in order to rapidly activate emergency services and for bystanders to begin cardiopulmonary resuscitation (CPR).
- Trial name
- DISPATCH (NCT03633370)
- Testing
- Multifaceted intervention including 3 components
- Where
- 15 sites in France
- Volunteers
- 2,481 people
- Sponsor
- University Hospital, Grenoble