Clinical trials: In-Hospital Cardiac Arrest
Cardiac Arrest
Effect of Vasopressin, Steroid, and Epinephrine Treatment in Patients With Out-of-hospital Cardiac Arrest
Steroid use could be considered for patients with weaker adrenal function among those with post-cardiac arrest (CA) return of spontaneous circulation (ROSC), according to the former study.
- Trial name
- NCT03317197
- Testing
- Control Group, Experimental Group 1, Experimental Group 2
- Where
- South Korea
- Volunteers
- 834 people
- Sponsor
- Korea University Guro Hospital
Cardiac Arrest, Out-Of-Hospital
The REVIVE-PEEP Trial: Positive End-expiratory Pressure Versus Sham Valve/Zero End-expiratory Pressure in Cardiopulmonary Resuscitation During Manual Ventilation to Improve Neurological Outcomes at Discharge in Adult Patients Suffering an Out-of-hospital Cardiac Arrest
The goal of this clinical trial is to learn if applying positive end-expiratory pressure (PEEP) during cardiopulmonary resuscitation (CPR) improves neurological outcome in adults with out-of-hospital cardiac arrest who receive an…
- Trial name
- REVIVE-PEEP (NCT07905482)
- Testing
- Fixed PEEP Valve
- Where
- 3 sites in Netherlands
- Volunteers
- 3,200 people
- Sponsor
- Jeroen van Eijk
Out-Of-Hospital Cardiac Arrest, Neurological Injury
NFL Dynamics as a Predictor Factor in Patients With Out of Hospital Cardiac Arrest
To investigate the pharmacodynamics of light chain of NFL in patients with out-of hospital cardiac arrest after successful resuscitation and determine the difference in the serum levels of NFL in patients with favorable…
- Trial name
- NCT05218278
- Where
- Slovenia
- Volunteers
- 60 people
- Sponsor
- University Medical Centre Maribor
Out-Of-Hospital Cardiac Arrest
AED-delivery Using Drones in Suspected OHCA
Time to defibrillation is the most important predictor of survival in cardiac arrest. Traditional emergency medical system response is often to slow.
- Trial name
- NCT04723368
- Testing
- Automated flying Drone carrying an Automated external defibrillator (AED)
- Where
- Sweden
- Volunteers
- 59 people
- Sponsor
- Karolinska Institutet
BLS, Out-Of-Hospital Cardiac Arrest
Geographical Association Between Basic Life Support Courses, Bystander Cardiopulmonary Resuscitation and Survival
Background Since 2001 when the Danish Cardiac Arrest Registry was first established several large-scale interventions aimed at the entire Danish population from all ages have been initiated.
- Trial name
- Geodata-BLS (NCT04353089)
- Testing
- Basic life support courses
- Where
- Denmark
- Volunteers
- 900,000 people, healthy volunteers welcome
- Sponsor
- Emergency Medical Services, Capital Region, Denmark
Cardiac Arrest, Resuscitation
Mechanical Versus Manual Cardiopulmonary Resuscitation
In this study, the investigators compared mechanical and manual chest compressions in in-hospital cardiac arrest cases.
- Trial name
- NCT04422938
- Testing
- Manuel chest compressions handled by clinicians, LUCAS™ 2 Chest Compression System
- Where
- Turkey (Türkiye)
- Volunteers
- 303 people
- Sponsor
- Ankara City Hospital Bilkent
In-hospital Cardiac Arrest
Poor Theoretical Knowledge and Self-assessed Ability of Cardiopulmonary Resuscitation Among In-hospital Healthcare Professionals: a Cross Sectional Study With Questionnaires.
Theoretical knowledge of cardiopulmonary resuscitation (CPR) is the foundation of being able to perform CPR in a cardiac arrest situation.
- Trial name
- NCT03498508
- Where
- 4 sites in Sweden
- Volunteers
- 3,044 people
- Sponsor
- Dalarna County Council, Sweden
Cardiac Arrest
Washington Study of Hemofiltration After Out-of-Hospital Cardiac Arrest
The purpose of this study is to assess the feasibility of hemofiltration in patients resuscitated from cardiac arrest. Cardiac arrest is the loss of mechanical activity of the heart including the loss of detectable pulse, or…
- Trial name
- NCT01509040
- Testing
- Standard Care, Low Volume Hemofiltration, High Volume Hemofiltration
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Washington
Cardiac Arrest, Out-Of-Hospital Cardiac Arrest
Early Neurological Assessment With Pupillometry in Cardiac Arrest During Resuscitation
Easy Care study wants to demonstrate a correlation between intra-CPR infrared quantitative pupillometry and return of spontaneous circulation (ROSC).
- Trial name
- EASY-CARE (NCT05192772)
- Testing
- NPi200
- Where
- Italy
- Volunteers
- 214 people
- Sponsor
- Societa Italiana Anestesia Analgesia Rianimazione e Terapia Intensiva
Heart Arrest
Oxidative Stress and Cardiac Arrest
Cardiac arrest is a major health problem reaching 375000 cases in Europe each year. Only 5 to 31 % survive after an out of hospital cardiac arrest (OHCA). The main complication after OHCA is the anoxic encephalopathy.
- Trial name
- NCT00888966
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Institut d'Anesthesiologie des Alpes Maritimes
Out-Of-Hospital Cardiac Arrest, Acute Coronary Syndrome
Cangrelor in Comatose Survivors of OHCA Undergoing Primary PCI
The main objective of the trial is to find out if 4-hour continuous infusion of parenteral P2Y12 inhibitor cangrelor at the start of primary percutaneous coronary intervention (PCI) immediately and effectively suppresses platelet…
- Trial name
- Cangrelor OHCA (NCT04005729)
- Testing
- Cangrelor 50 MG
- Where
- Slovenia
- Volunteers
- 30 people
- Sponsor
- University Medical Centre Ljubljana
Escalation of Care, Cardiopulmonary Arrest
Early Warning System for Clinical Deterioration on General Hospital Wards
The goal is to develop a two-tiered monitoring system to improve the care of patients at risk for clinical deterioration on general hospital wards (GHWs) at Barnes-Jewish Hospital (BJH).
- Conditions
- Escalation of Care, Cardiopulmonary Arrest, Respiratory Arrest, Severe Sepsis
- Trial name
- NCT01280942
- Testing
- EWS Nursing Alerts, Wireless Remote Sensor
- Where
- United States
- Volunteers
- 20,031 people
- Sponsor
- Washington University School of Medicine
Out-of-Hospital Cardiac Arrest
A Prospective, Multicenter Registry With Targeted Temperature Management After Out-of-hospital Cardiac Arrest in Korea
Therapeutic hypothermia after out-of-hospital cardiac arrest is considered as a standard care. However, optimal candidates, optimal dose, duration, timing of initiation and rate of rewarming is still unknown.
- Trial name
- NCT02827422
- Testing
- not provided
- Where
- South Korea
- Volunteers
- 1,800 people
- Sponsor
- Kyu Nam Park
Heart Arrest, Out-Of-Hospital, Wounds and Injuries
Pediatric Prehospital Airway Resuscitation Trial
This study is a Phase 3, multi-center, Bayesian Adaptive Sequential Platform Trial testing the effectiveness of different prehospital airway management strategies in the care of critically ill children.
- Conditions
- Heart Arrest, Out-Of-Hospital, Wounds and Injuries, Respiratory Insufficiency in Children, Child, Only
- Trial name
- Pedi-PART (NCT06364280)
- Testing
- BVM, SGA, ETI
- Where
- 10 sites in United States
- Volunteers
- 3,000 people
- Sponsor
- Ohio State University
Assess the Quality Ofmanagement of Children With Cardiorespiratory Arrest in Assuit University Children Hospital According to the( A H A)Guidelines
Managment of Cardiorespiratory Arrest
CPR will be done based on American Heart Association Guidelines for Cardiopulmonary Resuscitation (2015) and Emergency Cardiovascular Care of Pediatric and Neonatal Patients.
- Trial name
- clinicalaudit (NCT03131310)
- Testing
- clinical audit
- Volunteers
- 100 people
- Sponsor
- Assiut University
Cardiac Arrest
Basic Life Support Termination of Resuscitation Implementation Study
In Ontario, most people who experience a cardiac arrest at home (when their heart stops beating) only receive basic life support from Primary Care Paramedics (PCPs) and all are transported to the hospital.
- Trial name
- NCT00370461
- Where
- 7 sites in Canada
- Volunteers
- 350 people
- Sponsor
- Sunnybrook Health Sciences Centre
Medical Education, Simulation-based Training
Effects of High-Frequency In Situ Simulation-based Team Training on Clinical Performance During Pediatric Cardiac Arrest
Cardiac arrest in hospitalized children is a rare occurrence in general and for each healthcare professional in particular, making lack of routine in performing cardiopulmonary resuscitation a challenge.
- Conditions
- Medical Education, Simulation-based Training, In-hospital Cardiac Arrest, Pediatrics
- Trial name
- NCT06542861
- Testing
- High-frequency simulation-based team training
- Where
- Denmark
- Volunteers
- 1,200 people
- Sponsor
- University of Aarhus
Out-of-Hospital Cardiac Arrest
Transitions Between Clinical Circulatory States After Out-of-hospital Cardiac Arrest
Extensive research exists for cardio-pulmonary resuscitation (CPR) and the chance of successful return of spontaneous circulation (ROSC) is improved.
- Trial name
- NCT02648061
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- Norwegian University of Science and Technology
Out-Of-Hospital Cardiac Arrest
Medical Dispatchers' Perception of Visual Information in Real Out-of-hospital Cardiac Arrest
Dispatcher-assisted cardiopulmonary resuscitation is a complex, nonvisual procedure that is challenging for the dispatcher. The aim was to explore the medical dispatchers' perception of bystanders' responses and dispatchers'…
- Trial name
- NCT03721666
- Testing
- CCTV footage to the medical dispatcher in OHCA
- Volunteers
- 10 people
- Sponsor
- Emergency Medical Services, Capital Region, Denmark
Out-Of-Hospital Cardiac Arrest, Pediatric Disorder
Etiology, Incidence and Survival of Pediatric Out-of-hospital Cardiac Arrests: a Four-year Danish Analysis
Background: OHCA is a rare condition for children and young adults. Overall incidence rates are reported as 3.3-5.97 per 100.000 inhabitants.
- Conditions
- Out-Of-Hospital Cardiac Arrest, Pediatric Disorder, Cardiopulmonary Arrest
- Trial name
- Child-OHCA (NCT04275856)
- Where
- Denmark
- Volunteers
- 300 people
- Sponsor
- Emergency Medical Services, Capital Region, Denmark